|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
1.000
|
Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
1.000
|
|
|
|
bleb assembly
|
GO:0032060 |
6 |
1.000
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.999
|
Yeast |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.999
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.999
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.999
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.998
|
Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.997
|
Yeast Mouse Worm Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.996
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.996
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.996
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.995
|
Yeast Mouse Worm Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.995
|
Fly |
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.995
|
Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.992
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.992
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.991
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.991
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.990
|
Yeast Mouse Worm Fly |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.989
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.988
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.988
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.988
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.987
|
Yeast Mouse Worm Fly |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.987
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.980
|
Mouse Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.979
|
Yeast Mouse Worm Fly |
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.979
|
Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.978
|
Mouse Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.978
|
Yeast Mouse Worm Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.977
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.977
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.977
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.976
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.974
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.974
|
Worm Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.970
|
Yeast Mouse Worm Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.969
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.965
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.964
|
Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.963
|
Fly |
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.959
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.958
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.958
|
Yeast Mouse Worm Fly |
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.957
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.951
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.951
|
|
|
|
mechanosensory behavior
|
GO:0007638 |
4 |
0.951
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.950
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.949
|
Yeast Mouse Worm Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.943
|
Yeast Mouse Worm Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.942
|
Yeast Mouse Worm Fly |
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
22 |
0.942
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.939
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.937
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.931
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.926
|
Fly |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.922
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.920
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.919
|
Yeast Mouse Worm Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.919
|
Yeast Mouse Worm Fly |
|
|
determination of left right symmetry
|
GO:0007368 |
11 |
0.918
|
Fly |
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.915
|
Fly |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.915
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.912
|
Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.911
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.910
|
Yeast Mouse Worm Fly |
|
|
cellular response to histamine
|
GO:0071420 |
3 |
0.910
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.910
|
Yeast |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.910
|
Mouse |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.904
|
Worm |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.901
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.901
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.898
|
Yeast Mouse Worm Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.893
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.892
|
Yeast Mouse Worm Fly |
|
|
cytokinetic process
|
GO:0032506 |
12 |
0.892
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.892
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.889
|
Yeast Mouse Worm Fly |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.888
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.884
|
Mouse Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.883
|
Yeast Mouse Worm Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.881
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.879
|
Yeast Mouse Worm Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.876
|
Worm Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.869
|
Yeast |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.867
|
Mouse Worm Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.866
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.864
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.860
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.859
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.857
|
Yeast Mouse Worm Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.848
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.837
|
Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.831
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.827
|
Yeast Mouse Worm Fly |
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.827
|
Fly |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.823
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.819
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.818
|
Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.816
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.816
|
Yeast Mouse Worm Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.808
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.807
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.807
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.802
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.801
|
Fly |
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.798
|
Yeast |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.796
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.792
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.790
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.786
|
Yeast |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.784
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.784
|
Worm |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.780
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.775
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.773
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.768
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.761
|
Fly |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.757
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.751
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.750
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.747
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.747
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.746
|
Yeast |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.745
|
Fly |
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.740
|
Fly |
|
|
membrane to membrane docking
|
GO:0022614 |
5 |
0.736
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.733
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.727
|
Yeast |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.727
|
Fly |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.722
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.717
|
Fly |
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.710
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.706
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.692
|
Worm Fly |
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.692
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.679
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.673
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.665
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.660
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.659
|
Fly |
|
|
assembly of actomyosin apparatus involved in cytokinesis
|
GO:0000912 |
1 |
0.656
|
Worm Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.650
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.650
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.649
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.648
|
Worm Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.645
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.643
|
Fly |
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.639
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.632
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.621
|
Mouse |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.620
|
Worm |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.619
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.618
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.617
|
Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.616
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.611
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.609
|
Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.600
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.587
|
Yeast Mouse Worm Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.583
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.581
|
Yeast Mouse Worm Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.573
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.567
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.564
|
Human |
|
|
myoblast migration
|
GO:0051451 |
1 |
0.560
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.556
|
Mouse |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.554
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.545
|
Fly |
|
|
receptor internalization
|
GO:0031623 |
43 |
0.545
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.545
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.540
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.537
|
Fly |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.536
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.530
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.529
|
Fly |
|
|
nuclear division
|
GO:0000280 |
128 |
0.523
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.518
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.507
|
|
|
|
cortical actin cytoskeleton organization
|
GO:0030866 |
9 |
0.506
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.502
|
Fly |
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.492
|
Yeast Fly |
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.491
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.486
|
Yeast Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.479
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.477
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.458
|
Worm |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.450
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.442
|
|
|
|
secondary metabolic process
|
GO:0019748 |
17 |
0.442
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.437
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.427
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.425
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.418
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.417
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.416
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.413
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.413
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.412
|
|
|
|
mitotic cytokinetic process
|
GO:1902410 |
2 |
0.411
|
Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.409
|
Fly |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.396
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.393
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.387
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.373
|
Fly |
|
|
axis elongation
|
GO:0003401 |
4 |
0.371
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.366
|
Yeast |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.362
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.362
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.361
|
Human |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.360
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.356
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.350
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.347
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.340
|
Fly |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.334
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.331
|
Mouse |
|
|
regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000095 |
2 |
0.324
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.322
|
Yeast Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.322
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.317
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.311
|
Yeast Mouse Worm Fly |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.311
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.306
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.306
|
Fly |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.306
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.305
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.305
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.298
|
Human |
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.297
|
Fly |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.293
|
Worm Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.291
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.290
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.282
|
Fly |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.280
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.279
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.272
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.266
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.265
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.265
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.263
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.261
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.259
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.259
|
Fly |
|
|
stem cell division
|
GO:0017145 |
2 |
0.258
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.257
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.253
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.252
|
Human |
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.239
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.234
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.233
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.232
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.231
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.229
|
Human |
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.229
|
Yeast |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.229
|
|
|
|
lymphocyte aggregation
|
GO:0071593 |
1 |
0.227
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.226
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.224
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.223
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.223
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.223
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.220
|
|
|
|
actomyosin contractile ring organization
|
GO:0044837 |
1 |
0.220
|
Worm Fly |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.219
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.218
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.218
|
Worm |
|
|
system process
|
GO:0003008 |
349 |
0.217
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.217
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.215
|
Fly |
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.215
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.214
|
Worm Fly |
|
|
spindle organization
|
GO:0007051 |
53 |
0.213
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.212
|
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
5 |
0.209
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.209
|
Fly |
|
|
epidermis development
|
GO:0008544 |
59 |
0.207
|
Fly |
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.202
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.200
|
Mouse Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.199
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.199
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.198
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.196
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.195
|
Fly |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.192
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.190
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.190
|
Mouse Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.189
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.189
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
3 |
0.189
|
Worm |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.188
|
|
|
|
aging
|
GO:0007568 |
66 |
0.187
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.186
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.185
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.185
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.184
|
|
|
|
regulation of amine transport
|
GO:0051952 |
5 |
0.182
|
Worm |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.180
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.178
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.177
|
|
|
|
protein localization to adherens junction
|
GO:0071896 |
2 |
0.176
|
Fly |
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.174
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.174
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.173
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
12 |
0.172
|
Fly |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.170
|
Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.168
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.167
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.165
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.162
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.160
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.159
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.159
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.158
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.157
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.155
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.155
|
Fly |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.155
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.155
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.154
|
Yeast |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.153
|
Human |
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.152
|
Worm Fly |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.151
|
|
|
|
growth
|
GO:0040007 |
202 |
0.151
|
Yeast Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.150
|
Human |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.148
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.148
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.144
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.142
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.141
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.141
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.140
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.140
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.140
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.137
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.137
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.135
|
|
|
|
negative regulation of actin filament bundle assembly
|
GO:0032232 |
9 |
0.134
|
|
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.134
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.133
|
Worm Fly |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.132
|
Fly |
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.132
|
Worm |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.130
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.129
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.128
|
|
|
|
positive regulation of amine transport
|
GO:0051954 |
2 |
0.127
|
Worm |
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.127
|
|
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.127
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.126
|
Fly |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.126
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.125
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.125
|
Fly |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.123
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.122
|
Fly |
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.121
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.120
|
Fly |
|
|
ribonucleoprotein complex export from nucleus
|
GO:0071426 |
4 |
0.120
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.119
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.118
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.118
|
Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.117
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.117
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.115
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.115
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.115
|
Human |
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.115
|
Worm |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.114
|
Worm Fly |
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.114
|
|
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.113
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.113
|
Yeast Worm Fly |
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.113
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.111
|
|
|
|
apical junction assembly
|
GO:0043297 |
19 |
0.111
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.111
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.111
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.111
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.111
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.110
|
Fly |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.109
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.108
|
|
|
|
regulation of respiratory burst
|
GO:0060263 |
8 |
0.108
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.108
|
Worm |
|
|
behavior
|
GO:0007610 |
112 |
0.107
|
Worm |
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.106
|
Worm Fly |
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.106
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.106
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.105
|
Worm Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.105
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.104
|
Human |
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.103
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.102
|
|
|
|
trna transport
|
GO:0051031 |
1 |
0.102
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.101
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.100
|
Fly |
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.099
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.098
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.098
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.097
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.097
|
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.097
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.097
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.097
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.096
|
|
|
|
regulation of rrna processing
|
GO:2000232 |
1 |
0.096
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.096
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.095
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.094
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.093
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.093
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.093
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.091
|
|
|
|
ubiquitin dependent endocytosis
|
GO:0070086 |
1 |
0.091
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.090
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.090
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.089
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.089
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.089
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.089
|
|
|
|
membrane docking
|
GO:0022406 |
13 |
0.088
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.087
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.087
|
Mouse |
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.084
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.084
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.084
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.083
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.082
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.081
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.081
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.081
|
|
|
|
acetylcholine transport
|
GO:0015870 |
1 |
0.081
|
Worm |
|
|
cytokine production
|
GO:0001816 |
247 |
0.080
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.079
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.077
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.077
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.076
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.075
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.075
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.075
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.073
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.073
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.073
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.073
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.072
|
Worm |
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.071
|
|
|
|
positive regulation of synapse assembly
|
GO:0051965 |
5 |
0.071
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.071
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.071
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.069
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.069
|
Worm |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.069
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.069
|
Fly |
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.068
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.067
|
|
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.067
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.067
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.066
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.066
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.066
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.065
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.065
|
Mouse |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.065
|
|
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.064
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.064
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.064
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.064
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.063
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.063
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.063
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.062
|
Fly |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.062
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.062
|
Yeast |
|
|
membrane fusion
|
GO:0061025 |
43 |
0.062
|
Yeast |
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.061
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.061
|
|
|
|
snare complex assembly
|
GO:0035493 |
3 |
0.061
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.060
|
Fly |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.060
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.060
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.060
|
Fly |
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.059
|
|
|
|
regulation of coenzyme metabolic process
|
GO:0051196 |
3 |
0.059
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.058
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.058
|
|
