Homo sapiens

22 known processes

TMEM66

transmembrane protein 66

(Aliases: FOAP-7,FLJ22274,MGC8721,XTP3)

TMEM66 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
putrescine metabolic process GO:0009445 2 0.467
polyamine metabolic process GO:0006595 4 0.324
cellular macromolecule catabolic process GO:0044265 380 0.159
cellular amine metabolic process GO:0044106 41 0.145
amine metabolic process GO:0009308 44 0.066
cellular biogenic amine metabolic process GO:0006576 34 0.062
protein modification by small protein conjugation GO:0032446 342 0.052
negative regulation of cell proliferation GO:0008285 228 0.045
protein catabolic process GO:0030163 325 0.042
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.041
cellular protein catabolic process GO:0044257 261 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.040
protein ubiquitination GO:0016567 314 0.035
post embryonic development GO:0009791 2 0.034
multicellular organismal aging GO:0010259 3 0.033
modification dependent protein catabolic process GO:0019941 209 0.033
modification dependent macromolecule catabolic process GO:0043632 212 0.032
intracellular protein transport GO:0006886 270 0.031
proteasomal protein catabolic process GO:0010498 176 0.031
defense response GO:0006952 315 0.027
membrane organization GO:0061024 292 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
cellular amino acid metabolic process GO:0006520 116 0.025
response to endoplasmic reticulum stress GO:0034976 49 0.024
cellular chemical homeostasis GO:0055082 180 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
immune response GO:0006955 307 0.023
ubiquitin dependent protein catabolic process GO:0006511 206 0.023
chemical homeostasis GO:0048878 306 0.023
positive regulation of catabolic process GO:0009896 310 0.023
signal transduction by phosphorylation GO:0023014 297 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
spermine metabolic process GO:0008215 3 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
glycoprotein metabolic process GO:0009100 110 0.022
apoptotic signaling pathway GO:0097190 268 0.021
ras protein signal transduction GO:0007265 73 0.020
vesicle mediated transport GO:0016192 371 0.020
protein localization to membrane GO:0072657 160 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
cation homeostasis GO:0055080 189 0.020
cellular ion homeostasis GO:0006873 168 0.020
negative regulation of immune system process GO:0002683 136 0.018
ion homeostasis GO:0050801 230 0.018
glycosylation GO:0070085 71 0.018
protein glycosylation GO:0006486 62 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.017
single organism cellular localization GO:1902580 332 0.017
single organism membrane organization GO:0044802 268 0.017
determination of adult lifespan GO:0008340 2 0.017
mapk cascade GO:0000165 288 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
monovalent inorganic cation transport GO:0015672 128 0.016
regulation of cellular response to stress GO:0080135 244 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
negative regulation of protein modification process GO:0031400 200 0.016
protein maturation GO:0051604 233 0.016
circulatory system development GO:0072359 262 0.016
response to external biotic stimulus GO:0043207 261 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
innate immune response GO:0045087 178 0.016
negative regulation of catalytic activity GO:0043086 335 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
carbohydrate metabolic process GO:0005975 207 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
blood vessel morphogenesis GO:0048514 162 0.015
macromolecule glycosylation GO:0043413 63 0.015
metal ion transport GO:0030001 272 0.015
regulation of protein maturation GO:1903317 150 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
protein localization to organelle GO:0033365 280 0.015
memory GO:0007613 3 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
negative regulation of developmental process GO:0051093 247 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
dephosphorylation GO:0016311 209 0.014
cellular ketone metabolic process GO:0042180 80 0.014
regulation of secretion GO:0051046 194 0.014
regulation of cell differentiation GO:0045595 393 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
mitochondrion organization GO:0007005 156 0.014
rna processing GO:0006396 255 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
system process GO:0003008 349 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
positive regulation of cell death GO:0010942 263 0.013
cell projection organization GO:0030030 252 0.013
cation transport GO:0006812 331 0.013
nervous system development GO:0007399 293 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
metal ion homeostasis GO:0055065 169 0.013
nucleoside catabolic process GO:0009164 408 0.013
small molecule biosynthetic process GO:0044283 157 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
angiogenesis GO:0001525 147 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
regulation of protein localization GO:0032880 296 0.012
cell morphogenesis GO:0000902 296 0.012
organophosphate catabolic process GO:0046434 430 0.012
segmentation GO:0035282 4 0.012
inner ear morphogenesis GO:0042472 4 0.012
regulation of response to external stimulus GO:0032101 222 0.012
secretion GO:0046903 254 0.012
lipid metabolic process GO:0006629 381 0.012
plasma membrane organization GO:0007009 115 0.012
cell adhesion GO:0007155 325 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
regulation of leukocyte activation GO:0002694 115 0.012
positive regulation of immune system process GO:0002684 283 0.012
nitrogen compound transport GO:0071705 191 0.012
positive regulation of transport GO:0051050 336 0.012
cellular homeostasis GO:0019725 196 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
cytokine production GO:0001816 247 0.012
hindbrain development GO:0030902 3 0.012
mitochondrial membrane organization GO:0007006 40 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
mitotic cell cycle GO:0000278 326 0.012
cellular cation homeostasis GO:0030003 163 0.012
cellular response to dna damage stimulus GO:0006974 379 0.011
negative regulation of protein maturation GO:1903318 142 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
translation GO:0006412 132 0.011
regulation of gtpase activity GO:0043087 180 0.011
mitochondrial transport GO:0006839 60 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
response to abiotic stimulus GO:0009628 336 0.011
negative regulation of cell death GO:0060548 345 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
cytoplasmic transport GO:0016482 379 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
golgi vesicle transport GO:0048193 80 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
transmembrane transport GO:0055085 399 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
regulation of transferase activity GO:0051338 355 0.011
negative regulation of glycoprotein metabolic process GO:1903019 8 0.011
interspecies interaction between organisms GO:0044419 156 0.011
epithelium development GO:0060429 227 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
cation transmembrane transport GO:0098655 238 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
regulation of binding GO:0051098 111 0.011
biological adhesion GO:0022610 331 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
cellular lipid metabolic process GO:0044255 303 0.011
microtubule based process GO:0007017 210 0.010
regulation of intracellular transport GO:0032386 195 0.010
purine nucleotide catabolic process GO:0006195 405 0.010
chromatin organization GO:0006325 351 0.010
primary neural tube formation GO:0014020 3 0.010
endomembrane system organization GO:0010256 196 0.010
regulation of glycoprotein metabolic process GO:1903018 19 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
wnt signaling pathway GO:0016055 156 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.010
blood vessel development GO:0001568 172 0.010
regulation of ion transport GO:0043269 189 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
neuromuscular junction development GO:0007528 3 0.010
positive regulation of phosphorylation GO:0042327 394 0.010

TMEM66 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.039
inherited metabolic disorder DOID:655 242 0.015
sensory system disease DOID:0050155 203 0.015
nervous system disease DOID:863 431 0.015
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
musculoskeletal system disease DOID:17 223 0.012
central nervous system disease DOID:331 186 0.011
muscular disease DOID:0080000 114 0.010
muscle tissue disease DOID:66 113 0.010