Homo sapiens

155 known processes

SMC5

structural maintenance of chromosomes 5

(Aliases: KIAA0594,SMC5L1)

SMC5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 6 0.117
mitotic cell cycle phase transition GO:0044772 162 0.115
protein deubiquitination GO:0016579 79 0.114
cellular protein catabolic process GO:0044257 261 0.111
regulation of cellular ketone metabolic process GO:0010565 50 0.108
amine metabolic process GO:0009308 44 0.088
cellular macromolecule catabolic process GO:0044265 380 0.088
cellular ketone metabolic process GO:0042180 80 0.087
cellular amino acid metabolic process GO:0006520 116 0.087
vesicle mediated transport GO:0016192 371 0.085
response to organic cyclic compound GO:0014070 204 0.085
posttranscriptional regulation of gene expression GO:0010608 213 0.084
recombinational repair GO:0000725 50 0.081
dna conformation change GO:0071103 113 0.080
negative regulation of protein metabolic process GO:0051248 391 0.076
post embryonic development GO:0009791 2 0.074
negative regulation of cell death GO:0060548 345 0.072
female gamete generation GO:0007292 2 0.072
regulation of cell cycle GO:0051726 393 0.070
regulation of protein transport GO:0051223 213 0.066
regulation of cellular amine metabolic process GO:0033238 11 0.064
protein maturation GO:0051604 233 0.063
response to nitrogen compound GO:1901698 184 0.055
cellular response to dna damage stimulus GO:0006974 379 0.055
positive regulation of cellular component organization GO:0051130 376 0.054
cell division GO:0051301 168 0.054
organophosphate catabolic process GO:0046434 430 0.053
Yeast
cellular amine metabolic process GO:0044106 41 0.052
negative regulation of cellular amine metabolic process GO:0033239 3 0.052
regulation of mitotic cell cycle GO:0007346 189 0.052
cell projection organization GO:0030030 252 0.051
rna processing GO:0006396 255 0.051
negative regulation of phosphate metabolic process GO:0045936 267 0.047
response to abiotic stimulus GO:0009628 336 0.047
cellular macromolecular complex assembly GO:0034622 324 0.046
regulation of protein localization GO:0032880 296 0.044
dna packaging GO:0006323 77 0.044
mitotic cell cycle GO:0000278 326 0.043
positive regulation of cell cycle process GO:0090068 106 0.042
negative regulation of apoptotic process GO:0043066 316 0.041
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.040
regulation of proteolysis GO:0030162 293 0.038
anatomical structure homeostasis GO:0060249 100 0.038
protein dna complex subunit organization GO:0071824 80 0.037
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
regulation of cell cycle phase transition GO:1901987 126 0.036
nerve development GO:0021675 4 0.036
oogenesis GO:0048477 2 0.034
head development GO:0060322 108 0.034
metal ion transport GO:0030001 272 0.034
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
Yeast
glycosyl compound catabolic process GO:1901658 413 0.033
Yeast
regulation of translational initiation GO:0006446 24 0.032
nervous system development GO:0007399 293 0.032
protein modification by small protein removal GO:0070646 92 0.031
double strand break repair via homologous recombination GO:0000724 50 0.031
purine nucleotide catabolic process GO:0006195 405 0.031
Yeast
cell development GO:0048468 328 0.031
apoptotic signaling pathway GO:0097190 268 0.031
chromatin remodeling GO:0006338 55 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
cation transport GO:0006812 331 0.030
cell morphogenesis GO:0000902 296 0.030
cilium morphogenesis GO:0060271 75 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
regulation of gtp catabolic process GO:0033124 180 0.029
regulation of translation GO:0006417 89 0.029
cytoplasmic transport GO:0016482 379 0.029
regulation of cell cycle process GO:0010564 266 0.028
positive regulation of cell cycle GO:0045787 140 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
nucleotide catabolic process GO:0009166 408 0.027
Yeast
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
protein modification by small protein conjugation GO:0032446 342 0.027
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.026
mitotic cell cycle process GO:1903047 286 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
single organism cellular localization GO:1902580 332 0.026
meiotic chromosome segregation GO:0045132 4 0.025
negative regulation of protein modification process GO:0031400 200 0.025
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.025
response to caffeine GO:0031000 3 0.025
ion homeostasis GO:0050801 230 0.025
brain development GO:0007420 97 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.024
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
Yeast
chromatin modification GO:0016568 298 0.024
oocyte development GO:0048599 1 0.024
chromatin organization GO:0006325 351 0.024
positive regulation of programmed cell death GO:0043068 249 0.024
protein processing GO:0016485 226 0.023
receptor mediated endocytosis GO:0006898 84 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
morphogenesis of an epithelium GO:0002009 60 0.023
organelle assembly GO:0070925 176 0.023
rna splicing via transesterification reactions GO:0000375 90 0.023
translation GO:0006412 132 0.023
response to radiation GO:0009314 151 0.023
dna replication GO:0006260 116 0.023
actin cytoskeleton organization GO:0030036 207 0.022
modification dependent macromolecule catabolic process GO:0043632 212 0.022
neuromuscular junction development GO:0007528 3 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
forelimb morphogenesis GO:0035136 4 0.022
positive regulation of transport GO:0051050 336 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
regulation of transferase activity GO:0051338 355 0.021
chromosome segregation GO:0007059 114 0.021
negative regulation of mitotic cell cycle GO:0045930 102 0.021
endocytosis GO:0006897 159 0.021
intrinsic apoptotic signaling pathway GO:0097193 127 0.020
protein ubiquitination GO:0016567 314 0.020
dephosphorylation GO:0016311 209 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
nuclear division GO:0000280 128 0.020
rna splicing GO:0008380 131 0.020
cytokinesis GO:0000910 96 0.020
negative regulation of developmental process GO:0051093 247 0.020
central nervous system development GO:0007417 123 0.020
cell projection assembly GO:0030031 126 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
oocyte differentiation GO:0009994 2 0.019
response to growth factor GO:0070848 205 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
rna interference GO:0016246 4 0.019
cell projection morphogenesis GO:0048858 129 0.019
intracellular protein transport GO:0006886 270 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
single organism membrane organization GO:0044802 268 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
regulation of cell division GO:0051302 116 0.018
nitrogen compound transport GO:0071705 191 0.018
purine containing compound catabolic process GO:0072523 411 0.018
Yeast
regulation of dna metabolic process GO:0051052 153 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
Yeast
hindbrain development GO:0030902 3 0.018
interspecies interaction between organisms GO:0044419 156 0.018
dna dependent dna replication GO:0006261 44 0.018
regulation of dna replication GO:0006275 68 0.018
sister chromatid cohesion GO:0007062 24 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
Yeast
positive regulation of cell death GO:0010942 263 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
Yeast
organelle fission GO:0048285 149 0.017
response to organonitrogen compound GO:0010243 156 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
Yeast
negative regulation of phosphorylation GO:0042326 174 0.017
regulation of membrane potential GO:0042391 95 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
actin filament based process GO:0030029 224 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
Yeast
multicellular organismal aging GO:0010259 3 0.017
chemotaxis GO:0006935 157 0.017
dna recombination GO:0006310 77 0.017
cell part morphogenesis GO:0032990 137 0.017
ossification GO:0001503 121 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
system process GO:0003008 349 0.016
regulation of hormone levels GO:0010817 125 0.016
posttranscriptional gene silencing GO:0016441 25 0.016
viral process GO:0016032 146 0.016
determination of adult lifespan GO:0008340 2 0.016
mrna splicing via spliceosome GO:0000398 89 0.016
nucleosome positioning GO:0016584 3 0.016
cilium assembly GO:0042384 63 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
Yeast
positive regulation of gtpase activity GO:0043547 166 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
Yeast
embryo development GO:0009790 123 0.016
cellular component morphogenesis GO:0032989 314 0.016
transmembrane transport GO:0055085 399 0.015
nucleoside catabolic process GO:0009164 408 0.015
Yeast
negative regulation of hydrolase activity GO:0051346 182 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
Yeast
negative regulation of multicellular organismal process GO:0051241 317 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
dna repair GO:0006281 198 0.015
defense response GO:0006952 315 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
blastoderm segmentation GO:0007350 2 0.015
chromosome separation GO:0051304 23 0.015
response to light stimulus GO:0009416 87 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
response to uv GO:0009411 73 0.015
regulation of intracellular transport GO:0032386 195 0.015
response to lipid GO:0033993 206 0.015
membrane organization GO:0061024 292 0.014
immune effector process GO:0002252 159 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.014
regulation of angiogenesis GO:0045765 92 0.014
neuron differentiation GO:0030182 138 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
protein localization to organelle GO:0033365 280 0.014
biological adhesion GO:0022610 331 0.014
tissue migration GO:0090130 119 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
protein acetylation GO:0006473 116 0.013
regulation of mrna processing GO:0050684 48 0.013
regulation of locomotion GO:0040012 329 0.013
epithelium development GO:0060429 227 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
Yeast
eye development GO:0001654 42 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
response to fungus GO:0009620 4 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
Yeast
regulation of protein complex assembly GO:0043254 147 0.013
positive regulation of organelle organization GO:0010638 195 0.013
epidermis morphogenesis GO:0048730 3 0.013
neurogenesis GO:0022008 169 0.013
regulation of proteasomal protein catabolic process GO:0061136 87 0.013
macromolecule methylation GO:0043414 97 0.013
mitotic nuclear division GO:0007067 119 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
Yeast
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
Yeast
meiosis i GO:0007127 4 0.012
regulation of response to external stimulus GO:0032101 222 0.012
protein localization to membrane GO:0072657 160 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
cellular response to organic cyclic compound GO:0071407 127 0.012
urogenital system development GO:0001655 65 0.012
regulation of protein catabolic process GO:0042176 155 0.012
neuron development GO:0048666 113 0.012
regulation of gtpase activity GO:0043087 180 0.012
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
regulation of canonical wnt signaling pathway GO:0060828 88 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
taxis GO:0042330 157 0.012
regulation of cell motility GO:2000145 299 0.012
cell cycle phase transition GO:0044770 173 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
ribosomal protein import into nucleus GO:0006610 2 0.012
angiogenesis GO:0001525 147 0.011
protein sumoylation GO:0016925 25 0.011
mrna metabolic process GO:0016071 175 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
cilium organization GO:0044782 68 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
generation of neurons GO:0048699 152 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
double strand break repair GO:0006302 101 0.011
peptidyl serine modification GO:0018209 106 0.011
cell activation GO:0001775 213 0.011
forebrain neuron differentiation GO:0021879 3 0.011
response to oxidative stress GO:0006979 121 0.011
mrna processing GO:0006397 133 0.011
negative regulation of catabolic process GO:0009895 104 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
Yeast
cellular response to oxidative stress GO:0034599 85 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
Yeast
response to hormone GO:0009725 175 0.011
zymogen activation GO:0031638 70 0.011
cytokine production GO:0001816 247 0.011
epithelial cell migration GO:0010631 119 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
reproductive system development GO:0061458 56 0.011
negative regulation of transferase activity GO:0051348 124 0.011
lymphocyte activation GO:0046649 133 0.011
ribonucleoprotein complex subunit organization GO:0071826 81 0.011
regulation of mrna metabolic process GO:1903311 53 0.011
epithelial cell proliferation GO:0050673 128 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
negative regulation of protein processing GO:0010955 142 0.011
regulation of cellular response to stress GO:0080135 244 0.011
regulation of system process GO:0044057 101 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
histone exchange GO:0043486 3 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
microtubule based process GO:0007017 210 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
positive regulation of immune system process GO:0002684 283 0.010
regulation of cellular component movement GO:0051270 334 0.010
mapk cascade GO:0000165 288 0.010
secretion by cell GO:0032940 226 0.010
vasculature development GO:0001944 181 0.010
synaptic transmission cholinergic GO:0007271 2 0.010
sensory perception GO:0007600 103 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
cardiovascular system development GO:0072358 262 0.010
multi organism cellular process GO:0044764 156 0.010
sensory organ development GO:0007423 52 0.010
negative regulation of organelle organization GO:0010639 126 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
histone modification GO:0016570 251 0.010

SMC5 disease predictions

Disease DO term ID Size Probability Func Analog Org
joubert syndrome DOID:0050777 18 0.059
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
musculoskeletal system disease DOID:17 223 0.012