|
|
trail activated apoptotic signaling pathway
|
GO:0036462 |
4 |
0.988
|
|
|
|
b cell homeostasis
|
GO:0001782 |
1 |
0.854
|
|
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
7 |
0.775
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.764
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.716
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.705
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.683
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.665
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.664
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.647
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.641
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.624
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.617
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.610
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.607
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.601
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.589
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.585
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.582
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
15 |
0.574
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.554
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.554
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.526
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.513
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.484
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.473
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
1 |
0.464
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.455
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.448
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.444
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.443
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.441
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.438
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.436
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.432
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.422
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.419
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.415
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.403
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.399
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.399
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
7 |
0.398
|
Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.385
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.380
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.373
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.368
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.362
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.359
|
Fly |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.353
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.352
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.351
|
|
|
|
renal system process
|
GO:0003014 |
25 |
0.350
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.349
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.348
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.344
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.343
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.343
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.339
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.337
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.337
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.331
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.329
|
Fly |
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.327
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.324
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.324
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.319
|
Mouse Fly |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.319
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.318
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.317
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.317
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.316
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.316
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.314
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.313
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.312
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.312
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.310
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.306
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
5 |
0.305
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.304
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.301
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.301
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.300
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.298
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.298
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.297
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.297
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.294
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.293
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.292
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.289
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.287
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.286
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.281
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.279
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.278
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.276
|
Fly |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.273
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.270
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.270
|
Mouse Fly |
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.268
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.268
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.268
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.266
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.266
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.265
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.264
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.262
|
Mouse |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.262
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.260
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.254
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.253
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.249
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.247
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.246
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.244
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.242
|
Fly |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.241
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.241
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.239
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.232
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.229
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.225
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.224
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.224
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.221
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.220
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.209
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.208
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.207
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.206
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.205
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.205
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.203
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.201
|
|
|
|
response to cobalt ion
|
GO:0032025 |
1 |
0.199
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.198
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.196
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.193
|
|
|
|
response to dexamethasone
|
GO:0071548 |
1 |
0.189
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.189
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
29 |
0.185
|
|
|
|
cellular response to antibiotic
|
GO:0071236 |
1 |
0.183
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.182
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.177
|
|
|
|
system process
|
GO:0003008 |
349 |
0.175
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.173
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.172
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.171
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.171
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.169
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.168
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.168
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.166
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.166
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.166
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.166
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.165
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.163
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.163
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.160
|
Mouse |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.158
|
|
|
|
cellular response to xenobiotic stimulus
|
GO:0071466 |
29 |
0.156
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.150
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.149
|
|
|
|
response to antibiotic
|
GO:0046677 |
15 |
0.148
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.148
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.148
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.144
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.144
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.143
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.141
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.139
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.139
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.137
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.135
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.133
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.132
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.131
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.131
|
Fly |
|
|
head development
|
GO:0060322 |
108 |
0.129
|
Mouse |
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.128
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.128
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.128
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.126
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.124
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.124
|
Mouse |
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
11 |
0.123
|
Mouse |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.123
|
Mouse Fly |
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.122
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.122
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.117
|
Mouse |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.117
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.115
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.115
|
|
|
|
macrophage differentiation
|
GO:0030225 |
11 |
0.115
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.114
|
|
|
|
response to nicotine
|
GO:0035094 |
12 |
0.113
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.113
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.113
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.112
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.109
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.109
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.108
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.107
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.105
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.105
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.101
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.100
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.100
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.099
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.099
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.098
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.095
|
Mouse |
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.089
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.085
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
8 |
0.084
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.084
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.084
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.083
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.081
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.081
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.078
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.077
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.076
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.076
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.074
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.073
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.073
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.071
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.071
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.071
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.071
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.070
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.070
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.069
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.068
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.066
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.066
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.063
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.063
|
Mouse |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.063
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.062
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.060
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.058
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.058
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.058
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.058
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.057
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.055
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.054
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.053
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.053
|
Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.052
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.052
|
|
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.052
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.051
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.050
|
Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.048
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.047
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.046
|
Mouse |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.046
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.046
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.046
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.045
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.045
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.044
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.044
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.044
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.043
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.043
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.043
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.042
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.042
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.041
|
Fly |
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
12 |
0.041
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.040
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
6 |
0.039
|
Mouse |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.039
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.038
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.037
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.037
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.036
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.036
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.036
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.035
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.035
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.035
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.034
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.034
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.034
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.034
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.033
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.033
|
Mouse |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.033
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.033
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.032
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.032
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.032
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.031
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.031
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.031
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.031
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.030
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.030
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.030
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.030
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.030
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.029
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.029
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.029
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.029
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.029
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.028
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.028
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.028
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.028
|
Fly |
|
|
compound eye development
|
GO:0048749 |
1 |
0.028
|
Fly |
|
|
innate immune response
|
GO:0045087 |
178 |
0.028
|
Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.028
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.027
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.027
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.027
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.027
|
|
|
|
memory
|
GO:0007613 |
3 |
0.027
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.027
|
|
|
|
positive regulation of protein polyubiquitination
|
GO:1902916 |
3 |
0.026
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.026
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.026
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.026
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.025
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.025
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.025
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.025
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.025
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.025
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.025
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.025
|
Fly |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.025
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.025
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.024
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.024
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.024
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.024
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.024
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.024
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.024
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.024
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.024
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.024
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.024
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.024
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.024
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.024
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.023
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.023
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.023
|
|
|
|
positive regulation of protein monoubiquitination
|
GO:1902527 |
1 |
0.023
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.023
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
15 |
0.023
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.023
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.023
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.023
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.023
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.023
|
Fly |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.023
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.022
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.022
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.022
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.022
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.022
|
|
|
|
response to hexose
|
GO:0009746 |
20 |
0.022
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.022
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.022
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.022
|
|
|
|
cellular response to ketone
|
GO:1901655 |
9 |
0.021
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.021
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.021
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.021
|
Mouse Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.021
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.021
|
Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.021
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.021
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.021
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.021
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.021
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.021
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.021
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.021
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.021
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.021
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.020
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.020
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.020
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.020
|
Fly |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.020
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.020
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.020
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.020
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.020
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.020
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.020
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.020
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.020
|
|
|
|
positive regulation of protein k48 linked ubiquitination
|
GO:1902524 |
1 |
0.019
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.019
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
24 |
0.019
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.019
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.019
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.019
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.019
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.019
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.019
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
5 |
0.019
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.019
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.019
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.019
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.019
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.019
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.019
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.018
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.018
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.018
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.018
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.018
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.018
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.018
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.018
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.018
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.018
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.018
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.017
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.017
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.017
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.017
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.017
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.017
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.017
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.017
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.017
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.017
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.017
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.017
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.017
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.017
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.017
|
|
|
|
luteolysis
|
GO:0001554 |
3 |
0.017
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.017
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.017
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.017
|
|
|
|
protein autoprocessing
|
GO:0016540 |
4 |
0.016
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.016
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.016
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.016
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.016
|
|
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.016
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.016
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.016
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
Fly |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.016
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.016
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.016
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.016
|
Mouse |
|
|
dna repair
|
GO:0006281 |
198 |
0.016
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.016
|
Fly |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.016
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.016
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.015
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.015
|
Fly |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.015
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.015
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.015
|
Fly |
|
|
histone modification
|
GO:0016570 |
251 |
0.015
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.015
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.015
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.015
|
Fly |
|
|
nuclear import
|
GO:0051170 |
106 |
0.015
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.015
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.015
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.015
|
|
