|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.974
|
Human |
|
rhythmic behavior
|
GO:0007622 |
2 |
0.895
|
|
|
negative regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress
|
GO:1990441 |
1 |
0.884
|
Human |
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.875
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.803
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.802
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.744
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.735
|
Human |
|
circadian behavior
|
GO:0048512 |
2 |
0.724
|
|
|
histone modification
|
GO:0016570 |
251 |
0.544
|
Human |
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.512
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.470
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.445
|
|
|
sleep
|
GO:0030431 |
2 |
0.418
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.383
|
Human |
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.363
|
Fly |
|
compound eye development
|
GO:0048749 |
1 |
0.361
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.335
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.316
|
Fly |
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.277
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.274
|
Human |
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.272
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.264
|
Human |
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.256
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.256
|
|
|
cellular response to calcium ion
|
GO:0071277 |
19 |
0.245
|
Mouse |
|
viral gene expression
|
GO:0019080 |
35 |
0.245
|
Human |
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.244
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.244
|
Human |
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.239
|
Human |
|
response to calcium ion
|
GO:0051592 |
46 |
0.232
|
Mouse |
|
histone acetylation
|
GO:0016573 |
93 |
0.231
|
Human |
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.223
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.223
|
Fly |
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.219
|
Human |
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.208
|
Human |
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.207
|
Human |
|
negative regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0097201 |
5 |
0.196
|
Human |
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.194
|
Human |
|
wound healing
|
GO:0042060 |
115 |
0.181
|
Fly |
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.181
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.177
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.175
|
Human |
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.175
|
Human |
|
associative learning
|
GO:0008306 |
1 |
0.170
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.168
|
Fly |
|
negative regulation by host of viral transcription
|
GO:0043922 |
12 |
0.167
|
Human |
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.165
|
Human |
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.156
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.156
|
Human |
|
chromatin modification
|
GO:0016568 |
298 |
0.155
|
Human |
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.155
|
Human |
|
gtp catabolic process
|
GO:0006184 |
237 |
0.152
|
Human |
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.151
|
Human |
|
post embryonic development
|
GO:0009791 |
2 |
0.149
|
Worm Fly |
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.149
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.146
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
6 |
0.146
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.144
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.137
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.133
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.132
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.129
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.128
|
Human |
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.128
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.127
|
Human |
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.126
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.124
|
Human |
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.123
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.123
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.121
|
Human |
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.121
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.120
|
Human |
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.119
|
Human |
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.116
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.115
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.111
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.110
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.109
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.108
|
Human |
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.107
|
Human |
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.106
|
Human |
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.105
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.105
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.104
|
Fly |
|
response to growth factor
|
GO:0070848 |
205 |
0.104
|
Human |
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.103
|
|
|
immune response
|
GO:0006955 |
307 |
0.103
|
Fly |
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.102
|
Human |
|
single organism membrane organization
|
GO:0044802 |
268 |
0.100
|
Human |
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.100
|
Human |
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.100
|
Human |
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.099
|
Human |
|
protein acetylation
|
GO:0006473 |
116 |
0.098
|
Human |
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.098
|
Human |
|
hemopoiesis
|
GO:0030097 |
180 |
0.097
|
|
|
negative regulation of humoral immune response
|
GO:0002921 |
7 |
0.096
|
Fly |
|
protein acylation
|
GO:0043543 |
138 |
0.096
|
Human |
|
nervous system development
|
GO:0007399 |
293 |
0.095
|
Fly |
|
membrane organization
|
GO:0061024 |
292 |
0.095
|
Human |
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.092
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.091
|
Human |
|
blastocyst formation
|
GO:0001825 |
3 |
0.091
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.090
|
Human |
|
blastocyst development
|
GO:0001824 |
3 |
0.090
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.089
|
Human |
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.089
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.088
|
Human |
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.088
|
Mouse |
|
response to wounding
|
GO:0009611 |
168 |
0.087
|
Fly |
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.087
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
12 |
0.084
|
Fly |
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.084
|
Human |
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.084
|
Human |
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.084
|
Human |
|
blood vessel development
|
GO:0001568 |
172 |
0.083
|
|
|
response to camp
|
GO:0051591 |
25 |
0.082
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.081
|
Human |
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.079
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
0.079
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.079
|
|
|
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay
|
GO:1900151 |
8 |
0.078
|
|
|
positive regulation of mitochondrial membrane permeability
|
GO:0035794 |
17 |
0.078
|
Human |
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.077
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.077
|
Human |
|
embryonic placenta development
|
GO:0001892 |
1 |
0.075
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.074
|
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.074
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.074
|
Human |
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.074
|
Human |
|
circulatory system development
|
GO:0072359 |
262 |
0.074
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.073
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.073
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.072
|
Human |
|
viral process
|
GO:0016032 |
146 |
0.072
|
Human |
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.072
|
|
|
regeneration
|
GO:0031099 |
4 |
0.071
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.071
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.070
|
Human |
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.069
|
Human |
|
protein import
|
GO:0017038 |
130 |
0.069
|
Human |
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.068
|
Human |
|
gtp metabolic process
|
GO:0046039 |
239 |
0.068
|
Human |
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.067
|
Human |
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.065
|
|
|
embryo development
|
GO:0009790 |
123 |
0.065
|
Worm Fly |
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.064
|
Human |
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.063
|
Human |
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.062
|
|
|
positive regulation of mrna catabolic process
|
GO:0061014 |
10 |
0.061
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.061
|
Human |
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.061
|
Human |
|
mrna metabolic process
|
GO:0016071 |
175 |
0.061
|
|
|
growth
|
GO:0040007 |
202 |
0.060
|
Fly |
|
positive regulation of viral transcription
|
GO:0050434 |
13 |
0.059
|
Human |
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.059
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.058
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.058
|
Mouse |
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.058
|
Human |
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.057
|
Human |
|
regulation of immune response
|
GO:0050776 |
201 |
0.057
|
Fly |
|
endocytosis
|
GO:0006897 |
159 |
0.057
|
Fly |
|
epithelial cell migration
|
GO:0010631 |
119 |
0.057
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.056
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.056
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.055
|
|
|
gene silencing by mirna
|
GO:0035195 |
23 |
0.055
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.054
|
Fly |
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.054
|
Human |
|
histone h3 k27 demethylation
|
GO:0071557 |
3 |
0.053
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.053
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.053
|
Human |
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.053
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.053
|
|
|
regulation of mrna catabolic process
|
GO:0061013 |
13 |
0.053
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.052
|
Human |
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.052
|
Mouse |
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.052
|
|
|
cell development
|
GO:0048468 |
328 |
0.052
|
Mouse Fly |
|
protein localization to organelle
|
GO:0033365 |
280 |
0.052
|
Human |
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.051
|
Human |
|
cell activation
|
GO:0001775 |
213 |
0.051
|
|
|
translation
|
GO:0006412 |
132 |
0.051
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.050
|
|
|
cell growth
|
GO:0016049 |
160 |
0.050
|
|
|
immune system development
|
GO:0002520 |
195 |
0.050
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.049
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.048
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.048
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.047
|
Human |
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.047
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.047
|
Human |
|
negative regulation of dna binding
|
GO:0043392 |
18 |
0.047
|
Human |
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.047
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.046
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.046
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.046
|
Fly |
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.045
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.045
|
Fly |
|
generation of neurons
|
GO:0048699 |
152 |
0.045
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
9 |
0.044
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.044
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.044
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.044
|
Human |
|
nuclear import
|
GO:0051170 |
106 |
0.044
|
Human |
|
rhythmic process
|
GO:0048511 |
31 |
0.044
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.043
|
Human |
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.043
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.043
|
Mouse |
|
post embryonic hemopoiesis
|
GO:0035166 |
1 |
0.043
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.043
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.042
|
Fly |
|
muscle organ development
|
GO:0007517 |
56 |
0.042
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.042
|
Human |
|
behavior
|
GO:0007610 |
112 |
0.041
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.040
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.040
|
Human |
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.040
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.039
|
Fly |
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.039
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.039
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.039
|
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.038
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.038
|
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.038
|
Human |
|
cell morphogenesis
|
GO:0000902 |
296 |
0.038
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.038
|
Fly |
|
mrna processing
|
GO:0006397 |
133 |
0.037
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.037
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.037
|
Human |
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.037
|
|
|
positive regulation of mrna metabolic process
|
GO:1903313 |
19 |
0.037
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.036
|
Human |
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.036
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.036
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.036
|
Human |
|
reproductive process
|
GO:0022414 |
106 |
0.035
|
Fly |
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.035
|
Human |
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.035
|
Fly |
|
neurogenesis
|
GO:0022008 |
169 |
0.034
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.034
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.034
|
Human |
|
nuclear transport
|
GO:0051169 |
179 |
0.034
|
Human |
|
myoblast differentiation
|
GO:0045445 |
21 |
0.034
|
|
|
rna processing
|
GO:0006396 |
255 |
0.033
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.033
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.033
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.033
|
Human |
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.032
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.032
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.032
|
Human |
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.032
|
Fly |
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.031
|
Human |
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.031
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.031
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.031
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.031
|
Human |
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.031
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.030
|
Human |
|
cardiovascular system development
|
GO:0072358 |
262 |
0.030
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.030
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.030
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.030
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.030
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.030
|
|
|
response to virus
|
GO:0009615 |
126 |
0.030
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.030
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
24 |
0.029
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.029
|
Mouse |
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.029
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.029
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.029
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.029
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.028
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.028
|
Human |
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.028
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.028
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.028
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.027
|
Human Fly |
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
3 |
0.027
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.027
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.027
|
|
|
histone lysine demethylation
|
GO:0070076 |
14 |
0.026
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.026
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.026
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.026
|
Human |
|
synapse assembly
|
GO:0007416 |
8 |
0.026
|
Fly |
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.026
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.026
|
Human |
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.026
|
Human |
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.025
|
|
|
aging
|
GO:0007568 |
66 |
0.025
|
Fly |
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.025
|
|
|
microglial cell activation
|
GO:0001774 |
2 |
0.025
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.025
|
Fly |
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.025
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.025
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.025
|
|
|
segmentation
|
GO:0035282 |
4 |
0.025
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.025
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.025
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.025
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.024
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.024
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.024
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.023
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.023
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.023
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.023
|
|
|
positive regulation of heart contraction
|
GO:0045823 |
5 |
0.023
|
Fly |
|
histone demethylation
|
GO:0016577 |
15 |
0.023
|
|
|
decidualization
|
GO:0046697 |
4 |
0.023
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.023
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.023
|
Fly |
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.022
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.022
|
Human |
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.022
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.022
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.022
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.022
|
Fly |
|
hemoglobin metabolic process
|
GO:0020027 |
3 |
0.022
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.022
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.022
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.022
|
Fly |
|
oocyte differentiation
|
GO:0009994 |
2 |
0.022
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.022
|
Human |
|
gene silencing
|
GO:0016458 |
49 |
0.022
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.022
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.022
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.022
|
Human |
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.022
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.022
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.021
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.021
|
|
|
positive regulation of hemoglobin biosynthetic process
|
GO:0046985 |
1 |
0.021
|
|
|
system process
|
GO:0003008 |
349 |
0.020
|
Fly |
|
neuron differentiation
|
GO:0030182 |
138 |
0.020
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.020
|
Human |
|
regulation of cell division
|
GO:0051302 |
116 |
0.020
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.020
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.020
|
Human Fly |
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.020
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.020
|
Human |
|
hippocampus development
|
GO:0021766 |
1 |
0.020
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.020
|
|
|
neuron development
|
GO:0048666 |
113 |
0.019
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.019
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.019
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.019
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.019
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.019
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.019
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.019
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.019
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.019
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.019
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.019
|
Human |
|
response to lipid
|
GO:0033993 |
206 |
0.019
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.019
|
Human |
|
response to unfolded protein
|
GO:0006986 |
24 |
0.019
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.019
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.019
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.019
|
Fly |
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.019
|
Human |
|
muscle cell development
|
GO:0055001 |
29 |
0.019
|
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.018
|
Human |
|
macromolecule methylation
|
GO:0043414 |
97 |
0.018
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.018
|
Human |
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.018
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.018
|
|
|
demethylation
|
GO:0070988 |
37 |
0.018
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.018
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.018
|
|
|
nuclear transcribed mrna catabolic process
|
GO:0000956 |
48 |
0.018
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.018
|
Human |
|
regionalization
|
GO:0003002 |
29 |
0.018
|
|
|
mrna 3 end processing
|
GO:0031124 |
24 |
0.018
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.017
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.017
|
|
|
cellular response to fluid shear stress
|
GO:0071498 |
7 |
0.017
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.017
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.017
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.017
|
Human |
|
mapk cascade
|
GO:0000165 |
288 |
0.017
|
Fly |
|
developmental growth
|
GO:0048589 |
48 |
0.017
|
Fly |
|
head development
|
GO:0060322 |
108 |
0.017
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.017
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.017
|
Human |
|
cellular homeostasis
|
GO:0019725 |
196 |
0.017
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.017
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.017
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.017
|
Fly |
|
regulation of histone modification
|
GO:0031056 |
47 |
0.017
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.016
|
Human |
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.016
|
Human |
|
protein import into nucleus
|
GO:0006606 |
104 |
0.016
|
Human |
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.016
|
|
|
positive regulation of anoikis
|
GO:2000210 |
4 |
0.016
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.016
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.016
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.016
|
|
|
brain development
|
GO:0007420 |
97 |
0.016
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.016
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.016
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.016
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.016
|
Human |
|
rna 3 end processing
|
GO:0031123 |
35 |
0.016
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.016
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.015
|
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
26 |
0.015
|
Human |
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.015
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.015
|
|
|
dna replication
|
GO:0006260 |
116 |
0.015
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.015
|
Human |
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.015
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.015
|
Fly |
|
hexose metabolic process
|
GO:0019318 |
55 |
0.015
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.015
|
Fly |
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.015
|
Fly |
|
response to progesterone
|
GO:0032570 |
5 |
0.015
|
|
|
heart formation
|
GO:0060914 |
2 |
0.015
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.015
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.015
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.015
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.015
|
Human |
|
response to toxic substance
|
GO:0009636 |
37 |
0.015
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.015
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.015
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.015
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.015
|
Human |
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.015
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.014
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.014
|
Human |
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.014
|
Human |
|
reproduction
|
GO:0000003 |
63 |
0.014
|
Worm Fly |
|
endothelium development
|
GO:0003158 |
33 |
0.014
|
|
|
positive regulation of mrna 3 end processing
|
GO:0031442 |
12 |
0.014
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.014
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.014
|
Human |
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.014
|
|
|
spleen development
|
GO:0048536 |
1 |
0.014
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.014
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
16 |
0.014
|
Human |
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.014
|
|
|
female pregnancy
|
GO:0007565 |
17 |
0.014
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.014
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.014
|
Human |
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.014
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.014
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
23 |
0.014
|
Human |
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.014
|
Human |
|
regulation of mrna 3 end processing
|
GO:0031440 |
12 |
0.014
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.013
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.013
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.013
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.013
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.013
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.013
|
|
|
response to drug
|
GO:0042493 |
81 |
0.013
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.013
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.013
|
|
|
methylation
|
GO:0032259 |
106 |
0.013
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.013
|
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.013
|
|
|
protein dealkylation
|
GO:0008214 |
17 |
0.013
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.013
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.012
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.012
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.012
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.012
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.012
|
Human |
|
protein ubiquitination
|
GO:0016567 |
314 |
0.012
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.012
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.012
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.012
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.012
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.012
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.012
|
|
|
nuclear transcribed mrna poly a tail shortening
|
GO:0000289 |
8 |
0.012
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.012
|
Human |
|
maintenance of location
|
GO:0051235 |
112 |
0.012
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.012
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.012
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.012
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.012
|
|