Homo sapiens

96 known processes

TRAF4

TNF receptor-associated factor 4

(Aliases: RNF83,CART1,MLN62)

TRAF4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein ubiquitination GO:0016567 314 0.707
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.645
cellular amine metabolic process GO:0044106 41 0.499
amine metabolic process GO:0009308 44 0.479
cellular ketone metabolic process GO:0042180 80 0.441
protein modification by small protein conjugation GO:0032446 342 0.388
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.382
Human
ribosomal large subunit export from nucleus GO:0000055 3 0.342
cellular amino acid metabolic process GO:0006520 116 0.321
regulation of cellular amine metabolic process GO:0033238 11 0.312
enzyme linked receptor protein signaling pathway GO:0007167 303 0.298
cellular macromolecule catabolic process GO:0044265 380 0.296
regulation of cellular amino acid metabolic process GO:0006521 6 0.246
apoptotic signaling pathway GO:0097190 268 0.240
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.239
chromatin organization GO:0006325 351 0.237
ubiquitin dependent protein catabolic process GO:0006511 206 0.216
positive regulation of programmed cell death GO:0043068 249 0.214
Human
trna transport GO:0051031 1 0.213
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.199
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.199
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.197
negative regulation of apoptotic process GO:0043066 316 0.194
cell development GO:0048468 328 0.192
cellular protein catabolic process GO:0044257 261 0.179
modification dependent macromolecule catabolic process GO:0043632 212 0.178
modification dependent protein catabolic process GO:0019941 209 0.177
negative regulation of cell death GO:0060548 345 0.175
negative regulation of multicellular organismal process GO:0051241 317 0.172
regulation of mrna export from nucleus GO:0010793 3 0.167
common partner smad protein phosphorylation GO:0007182 3 0.163
purine containing compound catabolic process GO:0072523 411 0.159
response to oxygen containing compound GO:1901700 369 0.158
Human
mapk cascade GO:0000165 288 0.157
cellular response to endogenous stimulus GO:0071495 336 0.152
negative regulation of sodium ion transport GO:0010766 3 0.148
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.131
Human
covalent chromatin modification GO:0016569 254 0.126
regulation of map kinase activity GO:0043405 108 0.124
Human
negative regulation of programmed cell death GO:0043069 321 0.121
nervous system development GO:0007399 293 0.120
regulation of protein serine threonine kinase activity GO:0071900 179 0.119
Human
negative regulation of sodium ion transmembrane transport GO:1902306 2 0.117
cell adhesion GO:0007155 325 0.116
negative regulation of protein metabolic process GO:0051248 391 0.115
negative regulation of developmental process GO:0051093 247 0.115
interspecies interaction between organisms GO:0044419 156 0.114
negative regulation of cell proliferation GO:0008285 228 0.114
protein catabolic process GO:0030163 325 0.114
endodermal cell fate commitment GO:0001711 4 0.110
canonical wnt signaling pathway GO:0060070 116 0.109
negative regulation of sodium ion transmembrane transporter activity GO:2000650 2 0.108
peptidyl tyrosine phosphorylation GO:0018108 170 0.106
negative regulation of protein modification process GO:0031400 200 0.103
protein localization to organelle GO:0033365 280 0.101
regulation of canonical wnt signaling pathway GO:0060828 88 0.100
cell junction organization GO:0034330 79 0.099
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.097
Human
response to lipid GO:0033993 206 0.097
Human
single organism cell adhesion GO:0098602 179 0.095
smad protein complex assembly GO:0007183 12 0.095
positive regulation of cell death GO:0010942 263 0.094
Human
regulation of protein kinase activity GO:0045859 289 0.093
cofactor metabolic process GO:0051186 87 0.092
regulation of transferase activity GO:0051338 355 0.091
defense response GO:0006952 315 0.090
response to abiotic stimulus GO:0009628 336 0.089
wnt signaling pathway GO:0016055 156 0.087
positive regulation of catabolic process GO:0009896 310 0.086
i kappab kinase nf kappab signaling GO:0007249 166 0.086
Human
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 2 0.085
response to other organism GO:0051707 261 0.084
Human
regulation of proteolysis GO:0030162 293 0.084
Human
rho protein signal transduction GO:0007266 26 0.083
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.083
negative regulation of phosphorus metabolic process GO:0010563 267 0.080
regulation of cell differentiation GO:0045595 393 0.079
Human
positive regulation of cell development GO:0010720 92 0.079
viral process GO:0016032 146 0.078
negative regulation of pathway restricted smad protein phosphorylation GO:0060394 11 0.078
negative regulation of catalytic activity GO:0043086 335 0.077
regulation of mapk cascade GO:0043408 262 0.077
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.076
lateral mesoderm development GO:0048368 1 0.076
hard palate development GO:0060022 1 0.075
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.075
cellular response to abiotic stimulus GO:0071214 117 0.074
regulation of anatomical structure morphogenesis GO:0022603 286 0.073
negative regulation of cellular protein metabolic process GO:0032269 353 0.073
regulation of kinase activity GO:0043549 314 0.073
regulation of proteasomal protein catabolic process GO:0061136 87 0.072
regulation of cellular component biogenesis GO:0044087 281 0.072
response to biotic stimulus GO:0009607 276 0.071
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.070
mitotic cell cycle GO:0000278 326 0.070
cellular response to oxygen containing compound GO:1901701 276 0.069
Human
immune response GO:0006955 307 0.068
Human
response to transforming growth factor beta GO:0071559 94 0.068
regulation of protein catabolic process GO:0042176 155 0.066
histone modification GO:0016570 251 0.066
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.066
determination of left right asymmetry in lateral mesoderm GO:0003140 1 0.065
hemopoiesis GO:0030097 180 0.065
Human
carboxylic acid biosynthetic process GO:0046394 97 0.065
negative regulation of phosphorylation GO:0042326 174 0.064
regulation of apoptotic signaling pathway GO:2001233 175 0.064
Human
regulation of cell cell adhesion GO:0022407 57 0.064
innate immune response GO:0045087 178 0.064
female gamete generation GO:0007292 2 0.064
cell cycle phase transition GO:0044770 173 0.064
positive regulation of developmental process GO:0051094 314 0.063
Human
positive regulation of proteolysis GO:0045862 142 0.063
regulation of cell cycle GO:0051726 393 0.063
nucleoside catabolic process GO:0009164 408 0.063
endodermal cell fate specification GO:0001714 4 0.062
proteasomal protein catabolic process GO:0010498 176 0.061
lipid metabolic process GO:0006629 381 0.061
signal transduction by phosphorylation GO:0023014 297 0.061
quinone metabolic process GO:1901661 18 0.060
chemotaxis GO:0006935 157 0.060
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.058
extrinsic apoptotic signaling pathway GO:0097191 119 0.058
Human
cytoplasmic transport GO:0016482 379 0.057
positive regulation of cell differentiation GO:0045597 211 0.057
Human
generation of neurons GO:0048699 152 0.057
peptidyl tyrosine modification GO:0018212 170 0.056
zygotic specification of dorsal ventral axis GO:0007352 2 0.056
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.056
monocarboxylic acid metabolic process GO:0032787 185 0.056
regulation of cellular response to growth factor stimulus GO:0090287 76 0.056
response to host defenses GO:0052200 2 0.056
tube development GO:0035295 125 0.055
Mouse
regulation of membrane potential GO:0042391 95 0.055
regulation of cytokine production GO:0001817 232 0.055
Human
positive regulation of protein kinase activity GO:0045860 190 0.054
ubiquitin dependent endocytosis GO:0070086 1 0.054
ribonucleoside triphosphate catabolic process GO:0009203 391 0.054
biological adhesion GO:0022610 331 0.053
positive regulation of protein catabolic process GO:0045732 75 0.053
cell type specific apoptotic process GO:0097285 125 0.053
oogenesis GO:0048477 2 0.052
cell morphogenesis involved in differentiation GO:0000904 144 0.052
cytokine production GO:0001816 247 0.052
Human
protein processing GO:0016485 226 0.051
purine nucleotide catabolic process GO:0006195 405 0.051
retinal ganglion cell axon guidance GO:0031290 2 0.050
negative regulation of intracellular signal transduction GO:1902532 183 0.050
response to growth factor GO:0070848 205 0.050
ras protein signal transduction GO:0007265 73 0.050
positive regulation of ras gtpase activity GO:0032320 117 0.050
negative regulation of cell cycle GO:0045786 193 0.050
quinone biosynthetic process GO:1901663 6 0.050
regulation of mesoderm development GO:2000380 4 0.049
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.049
glycosyl compound catabolic process GO:1901658 413 0.049
isoprenoid biosynthetic process GO:0008299 9 0.049
ribonucleotide catabolic process GO:0009261 405 0.048
stem cell division GO:0017145 2 0.048
regulation of purine nucleotide catabolic process GO:0033121 205 0.048
positive regulation of dna templated transcription elongation GO:0032786 18 0.047
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.047
single organismal cell cell adhesion GO:0016337 148 0.047
positive regulation of cellular catabolic process GO:0031331 284 0.047
photoreceptor cell differentiation GO:0046530 2 0.047
cell cell junction organization GO:0045216 69 0.047
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.047
negative regulation of potassium ion transmembrane transport GO:1901380 5 0.046
cellular component morphogenesis GO:0032989 314 0.046
ribonucleoside triphosphate metabolic process GO:0009199 412 0.046
neurogenesis GO:0022008 169 0.045
small gtpase mediated signal transduction GO:0007264 78 0.045
positive regulation of rho gtpase activity GO:0032321 56 0.044
phosphatidylinositol mediated signaling GO:0048015 55 0.044
regulation of cell development GO:0060284 161 0.044
protein maturation GO:0051604 233 0.044
regulation of defense response GO:0031347 154 0.044
regulation of cell cycle process GO:0010564 266 0.044
positive regulation of protein ubiquitination GO:0031398 53 0.044
evasion or tolerance of defenses of other organism involved in symbiotic interaction GO:0051834 2 0.044
negative regulation of transferase activity GO:0051348 124 0.043
positive regulation of mapk cascade GO:0043410 190 0.043
purine nucleoside catabolic process GO:0006152 398 0.043
peptidyl lysine acetylation GO:0018394 101 0.043
purine ribonucleoside catabolic process GO:0046130 398 0.042
regulation of ras gtpase activity GO:0032318 128 0.042
single organism membrane organization GO:0044802 268 0.042
positive regulation of apoptotic process GO:0043065 246 0.042
Human
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.042
cell projection organization GO:0030030 252 0.042
negative regulation of chromatin silencing GO:0031936 4 0.042
inorganic ion transmembrane transport GO:0098660 231 0.042
regulation of cytoskeleton organization GO:0051493 177 0.041
response to external biotic stimulus GO:0043207 261 0.041
Human
positive regulation of wnt signaling pathway GO:0030177 54 0.041
epithelium development GO:0060429 227 0.041
regulation of stress activated mapk cascade GO:0032872 84 0.041
hindbrain development GO:0030902 3 0.041
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.041
regulation of protein localization GO:0032880 296 0.041
response to wounding GO:0009611 168 0.040
nucleoside phosphate catabolic process GO:1901292 412 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.039
chromatin modification GO:0016568 298 0.039
regulation of rho protein signal transduction GO:0035023 79 0.039
single organism cellular localization GO:1902580 332 0.039
protein acylation GO:0043543 138 0.039
vesicle mediated transport GO:0016192 371 0.039
regulation of epithelial to mesenchymal transition GO:0010717 37 0.038
positive regulation of dendrite morphogenesis GO:0050775 3 0.038
hematopoietic or lymphoid organ development GO:0048534 186 0.038
Human
spermatid development GO:0007286 4 0.038
regulation of erk1 and erk2 cascade GO:0070372 99 0.038
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.038
negative regulation of bmp signaling pathway GO:0030514 17 0.038
response to organic cyclic compound GO:0014070 204 0.037
regulation of intracellular transport GO:0032386 195 0.037
regulation of cell adhesion GO:0030155 166 0.037
somatic stem cell maintenance GO:0035019 4 0.037
late endosome to vacuole transport GO:0045324 2 0.037
progesterone receptor signaling pathway GO:0050847 3 0.037
evasion or tolerance of host defenses by virus GO:0019049 2 0.036
cell fate determination GO:0001709 3 0.036
multi organism cellular process GO:0044764 156 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
guanosine containing compound catabolic process GO:1901069 239 0.036
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.036
sodium ion transport GO:0006814 61 0.036
protein localization to nucleus GO:0034504 136 0.036
interaction with host GO:0051701 42 0.036
purine nucleoside triphosphate metabolic process GO:0009144 412 0.036
regulation of protein complex assembly GO:0043254 147 0.035
response to light stimulus GO:0009416 87 0.035
cell morphogenesis GO:0000902 296 0.035
isoprenoid metabolic process GO:0006720 39 0.035
fatty acid metabolic process GO:0006631 115 0.035
negative regulation of protein phosphorylation GO:0001933 140 0.035
positive regulation of gtp catabolic process GO:0033126 166 0.035
positive regulation of transport GO:0051050 336 0.035
formation of primary germ layer GO:0001704 42 0.034
endocytosis GO:0006897 159 0.034
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
bmp signaling pathway GO:0030509 49 0.034
cell part morphogenesis GO:0032990 137 0.034
cell junction assembly GO:0034329 67 0.034
actin filament based process GO:0030029 224 0.034
regulation of ribosome biogenesis GO:0090069 1 0.034
eye photoreceptor cell differentiation GO:0001754 2 0.034
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.034
positive regulation of cell cycle GO:0045787 140 0.033
ribonucleoside catabolic process GO:0042454 406 0.033
dissemination or transmission of organism from other organism involved in symbiotic interaction GO:0051821 1 0.033
establishment of protein localization to organelle GO:0072594 172 0.033
regulation of protein ubiquitination GO:0031396 95 0.033
regulation of cofactor metabolic process GO:0051193 3 0.033
spermatid differentiation GO:0048515 4 0.033
inorganic cation transmembrane transport GO:0098662 194 0.033
negative regulation of apoptotic signaling pathway GO:2001234 97 0.033
negative regulation of cell differentiation GO:0045596 171 0.032
regulation of response to external stimulus GO:0032101 222 0.032
cell division GO:0051301 168 0.032
tissue morphogenesis GO:0048729 96 0.032
ossification GO:0001503 121 0.032
regulation of protein transport GO:0051223 213 0.031
digestive tract morphogenesis GO:0048546 56 0.031
regulation of cellular protein catabolic process GO:1903362 96 0.031
polyprenol biosynthetic process GO:0016094 1 0.031
stress activated mapk cascade GO:0051403 93 0.031
cellular response to dna damage stimulus GO:0006974 379 0.031
cellular protein complex assembly GO:0043623 188 0.031
oxidoreduction coenzyme metabolic process GO:0006733 19 0.031
ribonucleoprotein complex localization GO:0071166 4 0.031
regulation of establishment of protein localization GO:0070201 242 0.031
regulation of cell migration GO:0030334 289 0.031
myeloid cell differentiation GO:0030099 117 0.030
Human
positive regulation of hydrolase activity GO:0051345 331 0.030
gtp catabolic process GO:0006184 237 0.030
internal protein amino acid acetylation GO:0006475 101 0.030
small molecule biosynthetic process GO:0044283 157 0.030
polyprenol metabolic process GO:0016093 3 0.029
regulation of multivesicular body size GO:0010796 1 0.029
response to virus GO:0009615 126 0.029
cell substrate adhesion GO:0031589 132 0.029
positive regulation of locomotion GO:0040017 186 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
digestive system development GO:0055123 75 0.029
organophosphate catabolic process GO:0046434 430 0.029
mesodermal cell fate commitment GO:0001710 2 0.029
rna processing GO:0006396 255 0.029
regulation of neurotransmitter secretion GO:0046928 3 0.029
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.029
Human
regulation of cell morphogenesis GO:0022604 153 0.029
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.029
Human
trna export from nucleus GO:0006409 1 0.028
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.028
blastoderm segmentation GO:0007350 2 0.028
hormone metabolic process GO:0042445 61 0.028
positive regulation of gtpase activity GO:0043547 166 0.028
tube morphogenesis GO:0035239 95 0.028
positive regulation of cell adhesion GO:0045785 84 0.028
neuromuscular junction development GO:0007528 3 0.028
fatty acid biosynthetic process GO:0006633 46 0.027
regulation of hormone levels GO:0010817 125 0.027
carbohydrate metabolic process GO:0005975 207 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
pattern specification process GO:0007389 43 0.027
avoidance of defenses of other organism involved in symbiotic interaction GO:0051832 2 0.027
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.027
internal peptidyl lysine acetylation GO:0018393 97 0.027
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.027
cellular response to nitrogen compound GO:1901699 144 0.027
establishment of ribosome localization GO:0033753 4 0.027
regulation of peptidase activity GO:0052547 180 0.027
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.027
protein k29 linked ubiquitination GO:0035519 4 0.027
immune effector process GO:0002252 159 0.026
Human
chemical homeostasis GO:0048878 306 0.026
alcohol metabolic process GO:0006066 114 0.026
regulation of ubiquitin protein transferase activity GO:0051438 28 0.026
guanosine containing compound metabolic process GO:1901068 244 0.026
response to inorganic substance GO:0010035 127 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
regulation of meiotic cell cycle GO:0051445 4 0.026
positive regulation of endopeptidase activity GO:0010950 84 0.026
neuron differentiation GO:0030182 138 0.026
regulation of endosome size GO:0051036 3 0.026
regulation of bmp signaling pathway GO:0030510 27 0.026
regulation of growth GO:0040008 165 0.026
ion transmembrane transport GO:0034220 338 0.026
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.026
nucleoside triphosphate catabolic process GO:0009143 394 0.025
protein targeting GO:0006605 187 0.025
protein localization to lysosome GO:0061462 11 0.025
intracellular protein transport GO:0006886 270 0.025
regulation of ras protein signal transduction GO:0046578 155 0.025
immune system development GO:0002520 195 0.025
Human
nitrogen compound transport GO:0071705 191 0.025
negative regulation of cell fate specification GO:0009996 3 0.025
response to host GO:0075136 2 0.025
regulation of epithelial cell proliferation GO:0050678 113 0.025
peripheral nervous system development GO:0007422 2 0.025
coenzyme metabolic process GO:0006732 65 0.025
growth GO:0040007 202 0.024
regulation of ligase activity GO:0051340 29 0.024
mitotic cell cycle process GO:1903047 286 0.024
transmission of virus GO:0019089 1 0.024
neurotransmitter secretion GO:0007269 4 0.024
peptidyl lysine modification GO:0018205 144 0.024
regulation of nervous system development GO:0051960 88 0.024
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.024
segmentation GO:0035282 4 0.024
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.024
negative regulation of growth GO:0045926 97 0.024
regulation of secretion GO:0051046 194 0.024
cdc42 protein signal transduction GO:0032488 4 0.024
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.024
regulation of actin cytoskeleton organization GO:0032956 116 0.023
positive regulation of transferase activity GO:0051347 227 0.023
response to cytokine GO:0034097 232 0.023
Human
adherens junction organization GO:0034332 36 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
ribosomal subunit export from nucleus GO:0000054 4 0.023
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.023
outflow tract septum morphogenesis GO:0003148 4 0.023
epidermis morphogenesis GO:0048730 3 0.023
ribonucleoprotein complex export from nucleus GO:0071426 4 0.023
transmembrane transport GO:0055085 399 0.023
organic acid biosynthetic process GO:0016053 97 0.023
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
dolichol metabolic process GO:0019348 3 0.022
establishment of planar polarity GO:0001736 3 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
steroid metabolic process GO:0008202 94 0.022
inositol lipid mediated signaling GO:0048017 55 0.022
meiosis i GO:0007127 4 0.022
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 1 0.022
trna processing GO:0008033 23 0.022
regulation of lipid biosynthetic process GO:0046890 47 0.022
positive regulation of lipid biosynthetic process GO:0046889 22 0.022
regulation of neurogenesis GO:0050767 82 0.022
secretion by cell GO:0032940 226 0.022
regulation of gtpase activity GO:0043087 180 0.022
negative regulation of cell cycle process GO:0010948 121 0.022
mitochondrion organization GO:0007005 156 0.022
post embryonic development GO:0009791 2 0.022
regulation of actin filament based process GO:0032970 141 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
dephosphorylation GO:0016311 209 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
protein monoubiquitination GO:0006513 39 0.021
regulation of rho gtpase activity GO:0032319 66 0.021
regulation of cysteine type endopeptidase activity GO:2000116 127 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
anterior posterior axis specification GO:0009948 2 0.021
regulation of carbohydrate metabolic process GO:0006109 54 0.021
regulation of binding GO:0051098 111 0.021
circulatory system development GO:0072359 262 0.021
motor neuron axon guidance GO:0008045 2 0.021
regulation of secretion by cell GO:1903530 177 0.021
peptidyl threonine modification GO:0018210 45 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.021
nuclear transport GO:0051169 179 0.021
lipid biosynthetic process GO:0008610 177 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.021
salivary gland morphogenesis GO:0007435 4 0.020
regulation of jnk cascade GO:0046328 73 0.020
negative regulation of peptidyl serine phosphorylation GO:0033137 8 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
dorsal ventral axis specification GO:0009950 7 0.020
peptidyl threonine phosphorylation GO:0018107 41 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
development involved in symbiotic interaction GO:0044111 1 0.020
establishment of tissue polarity GO:0007164 3 0.020
peptidyl serine phosphorylation GO:0018105 101 0.020
positive regulation of intracellular transport GO:0032388 104 0.020
morphogenesis of a polarized epithelium GO:0001738 3 0.020
lysosomal transport GO:0007041 33 0.020
negative regulation of kinase activity GO:0033673 106 0.020
ion homeostasis GO:0050801 230 0.020
negative regulation of mitotic cell cycle GO:0045930 102 0.020
regulation of neuron differentiation GO:0045664 70 0.020
cation transmembrane transport GO:0098655 238 0.020
positive regulation of peptidase activity GO:0010952 88 0.020
regulation of peptidyl serine phosphorylation GO:0033135 50 0.020
regulation of immune effector process GO:0002697 91 0.020
Human
protein import into nucleus GO:0006606 104 0.019
response to nitrogen compound GO:1901698 184 0.019
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.019
organ morphogenesis GO:0009887 147 0.019
regulation of protein localization to cell surface GO:2000008 15 0.019
epithelial to mesenchymal transition GO:0001837 48 0.019
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.019
neuron development GO:0048666 113 0.019
otic vesicle development GO:0071599 1 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
sodium ion transmembrane transport GO:0035725 59 0.019
negative regulation of protein localization to cell surface GO:2000009 5 0.019
activation of cysteine type endopeptidase activity GO:0097202 57 0.019
morphogenesis of embryonic epithelium GO:0016331 4 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
jnk cascade GO:0007254 80 0.019
protein k63 linked ubiquitination GO:0070534 31 0.019
Human
cation transport GO:0006812 331 0.019
protein acetylation GO:0006473 116 0.019
erk1 and erk2 cascade GO:0070371 104 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
regulation of cell growth GO:0001558 135 0.018
dna replication GO:0006260 116 0.018
membrane organization GO:0061024 292 0.018
asymmetric stem cell division GO:0098722 1 0.018
positive regulation of cell migration GO:0030335 172 0.018
stem cell development GO:0048864 69 0.018
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.018
secretion GO:0046903 254 0.018
dolichol biosynthetic process GO:0019408 1 0.018
ectodermal placode development GO:0071696 1 0.018
locomotory behavior GO:0007626 1 0.018
leukocyte differentiation GO:0002521 98 0.018
Human
regulation of transmembrane transporter activity GO:0022898 74 0.018
regulation of cellular component movement GO:0051270 334 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
embryo development GO:0009790 123 0.018
oocyte differentiation GO:0009994 2 0.018
regulation of rrna processing GO:2000232 1 0.018
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage GO:0010767 1 0.018
nucleotide catabolic process GO:0009166 408 0.018
modulation by virus of host morphology or physiology GO:0019048 10 0.018
negative regulation of transmembrane transport GO:0034763 29 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
epithelial cell proliferation GO:0050673 128 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
intracellular receptor signaling pathway GO:0030522 104 0.017
ribosome localization GO:0033750 4 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.017
actin cytoskeleton organization GO:0030036 207 0.017
regulation of fatty acid metabolic process GO:0019217 24 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.017
Human
regulation of protein processing GO:0070613 150 0.017
sensory organ development GO:0007423 52 0.017
cellular response to organic cyclic compound GO:0071407 127 0.017
compound eye development GO:0048749 1 0.017
cardiovascular system development GO:0072358 262 0.017
response to bacterium GO:0009617 144 0.017
Human
protein homooligomerization GO:0051260 100 0.017
Human
cell fate commitment involved in pattern specification GO:0060581 1 0.017

TRAF4 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.044
disease of cellular proliferation DOID:14566 174 0.044
organ system cancer DOID:0050686 164 0.035
immune system disease DOID:2914 155 0.020