Homo sapiens

54 known processes

COMMD6

COMM domain containing 6

(Aliases: Acrg)

COMMD6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
hypoxia inducible factor 1alpha signaling pathway GO:0097411 3 0.136
modification dependent protein catabolic process GO:0019941 209 0.085
cation homeostasis GO:0055080 189 0.084
chemical homeostasis GO:0048878 306 0.083
post embryonic development GO:0009791 2 0.075
regulation of cellular response to stress GO:0080135 244 0.072
response to abiotic stimulus GO:0009628 336 0.061
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.061
metal ion homeostasis GO:0055065 169 0.059
copper ion homeostasis GO:0055070 3 0.058
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.056
transition metal ion homeostasis GO:0055076 31 0.055
protein catabolic process GO:0030163 325 0.055
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.053
protein modification by small protein conjugation GO:0032446 342 0.051
cellular macromolecule catabolic process GO:0044265 380 0.049
proteasomal protein catabolic process GO:0010498 176 0.049
cellular protein catabolic process GO:0044257 261 0.048
modification dependent macromolecule catabolic process GO:0043632 212 0.047
intracellular protein transport GO:0006886 270 0.044
ion homeostasis GO:0050801 230 0.044
response to decreased oxygen levels GO:0036293 96 0.044
cellular amino acid metabolic process GO:0006520 116 0.043
amine metabolic process GO:0009308 44 0.037
ubiquitin dependent protein catabolic process GO:0006511 206 0.036
response to cytokine GO:0034097 232 0.036
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.034
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
cellular response to cytokine stimulus GO:0071345 181 0.034
regulation of proteasomal protein catabolic process GO:0061136 87 0.033
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.032
posttranscriptional regulation of gene expression GO:0010608 213 0.032
negative regulation of protein metabolic process GO:0051248 391 0.032
female gamete generation GO:0007292 2 0.031
cellular amine metabolic process GO:0044106 41 0.031
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.030
segmentation GO:0035282 4 0.030
regulation of cell cycle GO:0051726 393 0.029
small gtpase mediated signal transduction GO:0007264 78 0.028
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.028
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.028
single organism membrane organization GO:0044802 268 0.027
neuromuscular junction development GO:0007528 3 0.027
regulation of protein catabolic process GO:0042176 155 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
response to oxygen containing compound GO:1901700 369 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
cytoplasmic transport GO:0016482 379 0.026
innate immune response GO:0045087 178 0.026
carbohydrate metabolic process GO:0005975 207 0.026
cell cycle phase transition GO:0044770 173 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.025
response to oxygen levels GO:0070482 100 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
negative regulation of intracellular signal transduction GO:1902532 183 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of protein stability GO:0031647 87 0.024
mitotic cell cycle GO:0000278 326 0.024
anterior posterior axis specification GO:0009948 2 0.024
cation transmembrane transport GO:0098655 238 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
protein ubiquitination GO:0016567 314 0.023
ras protein signal transduction GO:0007265 73 0.023
determination of adult lifespan GO:0008340 2 0.023
transmembrane transport GO:0055085 399 0.023
cation transport GO:0006812 331 0.023
regulation of endopeptidase activity GO:0052548 170 0.022
organonitrogen compound biosynthetic process GO:1901566 200 0.022
small molecule biosynthetic process GO:0044283 157 0.022
purine ribonucleotide catabolic process GO:0009154 404 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
organophosphate catabolic process GO:0046434 430 0.022
ion transmembrane transport GO:0034220 338 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
cellular response to oxygen containing compound GO:1901701 276 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
cellular response to decreased oxygen levels GO:0036294 51 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
rho protein signal transduction GO:0007266 26 0.020
response to external biotic stimulus GO:0043207 261 0.020
oogenesis GO:0048477 2 0.020
maintenance of location GO:0051235 112 0.020
cellular response to hypoxia GO:0071456 51 0.020
purine containing compound catabolic process GO:0072523 411 0.020
defense response GO:0006952 315 0.020
metal ion transport GO:0030001 272 0.020
memory GO:0007613 3 0.019
regeneration GO:0031099 4 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
cellular ketone metabolic process GO:0042180 80 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
response to tumor necrosis factor GO:0034612 76 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
regulation of cellular protein catabolic process GO:1903362 96 0.019
nucleotide catabolic process GO:0009166 408 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
locomotory behavior GO:0007626 1 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
cellular response to oxygen levels GO:0071453 55 0.018
regulation of meiotic cell cycle GO:0051445 4 0.018
immune response GO:0006955 307 0.018
nervous system development GO:0007399 293 0.018
nucleoside triphosphate catabolic process GO:0009143 394 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
positive regulation of protein ubiquitination GO:0031398 53 0.018
regulation of transferase activity GO:0051338 355 0.018
cytokine production GO:0001816 247 0.017
regulation of kinase activity GO:0043549 314 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.017
mating GO:0007618 1 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
purine nucleotide catabolic process GO:0006195 405 0.017
cell morphogenesis GO:0000902 296 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
cytokine mediated signaling pathway GO:0019221 109 0.017
membrane organization GO:0061024 292 0.017
gtp catabolic process GO:0006184 237 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
blastoderm segmentation GO:0007350 2 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
positive regulation of catabolic process GO:0009896 310 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
mitotic nuclear division GO:0007067 119 0.016
regulation of protein ubiquitination GO:0031396 95 0.016
positive regulation of cell death GO:0010942 263 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
regulation of cell cycle process GO:0010564 266 0.015
microtubule based process GO:0007017 210 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
lipid metabolic process GO:0006629 381 0.015
vesicle mediated transport GO:0016192 371 0.015
response to other organism GO:0051707 261 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
regulation of cytokine secretion GO:0050707 57 0.015
protein maturation GO:0051604 233 0.015
oocyte development GO:0048599 1 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
nucleoside catabolic process GO:0009164 408 0.015
protein secretion GO:0009306 98 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
protein targeting GO:0006605 187 0.014
regulation of feeding behavior GO:0060259 3 0.014
peripheral nervous system development GO:0007422 2 0.014
regulation of multi organism process GO:0043900 157 0.014
negative regulation of kinase activity GO:0033673 106 0.014
wnt signaling pathway GO:0016055 156 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
regulation of activation of jak2 kinase activity GO:0010534 5 0.014
spindle elongation GO:0051231 4 0.014
actin filament based process GO:0030029 224 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
cell projection organization GO:0030030 252 0.014
regulation of chromosome organization GO:0033044 103 0.014
biological adhesion GO:0022610 331 0.014
negative regulation of cell cycle GO:0045786 193 0.014
cellular homeostasis GO:0019725 196 0.014
stem cell division GO:0017145 2 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
circulatory system development GO:0072359 262 0.013
sensory perception of smell GO:0007608 2 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
cell projection morphogenesis GO:0048858 129 0.013
multicellular organismal aging GO:0010259 3 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
negative regulation of protein modification process GO:0031400 200 0.013
protein localization to organelle GO:0033365 280 0.013
protein import GO:0017038 130 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
mitotic cell cycle process GO:1903047 286 0.013
rna processing GO:0006396 255 0.013
regulation of protein kinase activity GO:0045859 289 0.013
regulation of cytokine production GO:0001817 232 0.013
regulation of protein maturation GO:1903317 150 0.013
protein localization to membrane GO:0072657 160 0.013
neuron development GO:0048666 113 0.013
regulation of innate immune response GO:0045088 97 0.013
regulation of peptidase activity GO:0052547 180 0.013
regulation of response to external stimulus GO:0032101 222 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
sensory perception of pain GO:0019233 4 0.013
positive regulation of organelle organization GO:0010638 195 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.012
meiotic chromosome segregation GO:0045132 4 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
response to bacterium GO:0009617 144 0.012
single organism cellular localization GO:1902580 332 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of protein processing GO:0070613 150 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
regulation of gtpase activity GO:0043087 180 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
dna repair GO:0006281 198 0.012
regulation of cellular component movement GO:0051270 334 0.012
response to inorganic substance GO:0010035 127 0.012
gtp metabolic process GO:0046039 239 0.012
response to acid chemical GO:0001101 66 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
response to organic cyclic compound GO:0014070 204 0.012
cell part morphogenesis GO:0032990 137 0.012
positive regulation of transport GO:0051050 336 0.012
response to fungus GO:0009620 4 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
positive regulation of kinase activity GO:0033674 204 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
negative regulation of cell death GO:0060548 345 0.012
covalent chromatin modification GO:0016569 254 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
spermatid differentiation GO:0048515 4 0.012
positive regulation of cytokine production GO:0001819 167 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
negative regulation of transport GO:0051051 176 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
endomembrane system organization GO:0010256 196 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
lipid localization GO:0010876 106 0.011
negative regulation of proteolysis GO:0045861 132 0.011
system process GO:0003008 349 0.011
positive regulation of proteolysis GO:0045862 142 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
positive regulation of cell cycle GO:0045787 140 0.011
regulation of protein transport GO:0051223 213 0.011
negative regulation of protein processing GO:0010955 142 0.011
defense response to fungus GO:0050832 4 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
regulation of protein localization GO:0032880 296 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
mitochondrion organization GO:0007005 156 0.011
spermatid development GO:0007286 4 0.011
response to biotic stimulus GO:0009607 276 0.011
response to lipid GO:0033993 206 0.011
regulation of cell motility GO:2000145 299 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
tripartite regional subdivision GO:0007351 2 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.011
response to nitrogen compound GO:1901698 184 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
negative regulation of response to cytokine stimulus GO:0060761 25 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
response to drug GO:0042493 81 0.011
response to interferon gamma GO:0034341 39 0.011
endosomal transport GO:0016197 129 0.010
divalent inorganic cation transport GO:0072511 158 0.010
immune system development GO:0002520 195 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
anatomical structure formation involved in morphogenesis GO:0048646 284 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
response to organonitrogen compound GO:0010243 156 0.010
regulation of cell differentiation GO:0045595 393 0.010
endocytosis GO:0006897 159 0.010
response to wounding GO:0009611 168 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
positive regulation of developmental process GO:0051094 314 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
protein processing GO:0016485 226 0.010
neurotransmitter secretion GO:0007269 4 0.010
chromosome segregation GO:0007059 114 0.010
interspecies interaction between organisms GO:0044419 156 0.010
translation GO:0006412 132 0.010
nucleoside monophosphate metabolic process GO:0009123 191 0.010
organelle assembly GO:0070925 176 0.010
activation of immune response GO:0002253 114 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010

COMMD6 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
disease of metabolism DOID:0014667 295 0.019
sensory system disease DOID:0050155 203 0.014
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
inherited metabolic disorder DOID:655 242 0.013
musculoskeletal system disease DOID:17 223 0.013
neurodegenerative disease DOID:1289 102 0.011