Homo sapiens

0 known processes

SHFM1

split hand/foot malformation (ectrodactyly) type 1

(Aliases: ECD,SHFD1,SHSF1,Shfdg1,SEM1,DSS1)

SHFM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 212 0.607
cellular macromolecule catabolic process GO:0044265 380 0.590
oocyte differentiation GO:0009994 2 0.573
determination of adult lifespan GO:0008340 2 0.497
female gamete generation GO:0007292 2 0.429
Worm
post embryonic development GO:0009791 2 0.424
Worm
oocyte development GO:0048599 1 0.302
cell development GO:0048468 328 0.289
Worm
regulation of meiotic cell cycle GO:0051445 4 0.244
dna repair GO:0006281 198 0.240
Mouse
oogenesis GO:0048477 2 0.223
Worm
multicellular organismal aging GO:0010259 3 0.217
spermatid development GO:0007286 4 0.204
nuclear division GO:0000280 128 0.201
mitochondrion organization GO:0007005 156 0.199
regulation of cell cycle GO:0051726 393 0.192
proteasomal protein catabolic process GO:0010498 176 0.173
cellular protein catabolic process GO:0044257 261 0.158
spermatid differentiation GO:0048515 4 0.149
modification dependent protein catabolic process GO:0019941 209 0.148
meiotic chromosome segregation GO:0045132 4 0.144
ubiquitin dependent protein catabolic process GO:0006511 206 0.140
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.139
ribonucleoside catabolic process GO:0042454 406 0.136
purine ribonucleoside catabolic process GO:0046130 398 0.135
regulation of meiosis GO:0040020 3 0.120
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.118
purine ribonucleoside metabolic process GO:0046128 437 0.118
cellular macromolecular complex assembly GO:0034622 324 0.111
organelle fission GO:0048285 149 0.107
protein catabolic process GO:0030163 325 0.104
negative regulation of cellular catabolic process GO:0031330 83 0.103
purine nucleoside monophosphate catabolic process GO:0009128 158 0.101
cellular protein complex assembly GO:0043623 188 0.098
mitotic nuclear division GO:0007067 119 0.096
regulation of proteasomal protein catabolic process GO:0061136 87 0.093
regulation of mitotic cell cycle GO:0007346 189 0.093
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.089
rna interference GO:0016246 4 0.087
blastocyst development GO:0001824 3 0.086
single organism cellular localization GO:1902580 332 0.082
regulation of endopeptidase activity GO:0052548 170 0.077
ribonucleoside triphosphate catabolic process GO:0009203 391 0.076
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.074
cellular response to dna damage stimulus GO:0006974 379 0.074
Mouse
dna recombination GO:0006310 77 0.074
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.073
mitotic sister chromatid segregation GO:0000070 53 0.070
reproduction GO:0000003 63 0.069
Worm
purine nucleoside triphosphate catabolic process GO:0009146 392 0.068
regulation of cell cycle process GO:0010564 266 0.067
regulation of proteolysis GO:0030162 293 0.064
positive regulation of catabolic process GO:0009896 310 0.063
regulation of cell division GO:0051302 116 0.062
single fertilization GO:0007338 11 0.058
nuclear migration GO:0007097 1 0.058
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.057
protein processing GO:0016485 226 0.055
organophosphate catabolic process GO:0046434 430 0.055
neurogenesis GO:0022008 169 0.054
Fly
negative regulation of peptidase activity GO:0010466 91 0.052
regulation of nuclear division GO:0051783 65 0.049
mitotic cell cycle process GO:1903047 286 0.047
ras protein signal transduction GO:0007265 73 0.046
nuclear transcribed mrna catabolic process GO:0000956 48 0.046
cell division GO:0051301 168 0.045
rho protein signal transduction GO:0007266 26 0.044
nucleotide catabolic process GO:0009166 408 0.043
small gtpase mediated signal transduction GO:0007264 78 0.043
ribonucleotide catabolic process GO:0009261 405 0.043
autophagy GO:0006914 88 0.042
positive regulation of cell death GO:0010942 263 0.042
anterior posterior axis specification GO:0009948 2 0.041
chromosome segregation GO:0007059 114 0.041
nucleotide excision repair GO:0006289 31 0.040
mitotic cell cycle GO:0000278 326 0.040
circulatory system process GO:0003013 113 0.040
positive regulation of proteolysis GO:0045862 142 0.039
nucleus localization GO:0051647 1 0.039
aging GO:0007568 66 0.037
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.037
male meiosis GO:0007140 1 0.036
tripartite regional subdivision GO:0007351 2 0.036
positive regulation of hydrolase activity GO:0051345 331 0.036
endocytosis GO:0006897 159 0.035
purine nucleoside catabolic process GO:0006152 398 0.033
negative regulation of protein processing GO:0010955 142 0.033
negative regulation of endopeptidase activity GO:0010951 84 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
hindbrain development GO:0030902 3 0.032
regulation of autophagy GO:0010506 52 0.032
organic hydroxy compound metabolic process GO:1901615 147 0.032
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.031
glycosyl compound catabolic process GO:1901658 413 0.031
sexual reproduction GO:0019953 37 0.031
Worm
negative regulation of catabolic process GO:0009895 104 0.031
regulation of cellular response to stress GO:0080135 244 0.031
regulation of peptidase activity GO:0052547 180 0.031
meiosis i GO:0007127 4 0.030
protein maturation GO:0051604 233 0.029
central nervous system development GO:0007417 123 0.029
single organism reproductive process GO:0044702 98 0.028
Worm
multicellular organism reproduction GO:0032504 42 0.028
Worm
regulation of protein catabolic process GO:0042176 155 0.028
developmental process involved in reproduction GO:0003006 66 0.028
Worm
growth GO:0040007 202 0.028
Worm
regulation of apoptotic signaling pathway GO:2001233 175 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.027
interspecies interaction between organisms GO:0044419 156 0.027
nitrogen compound transport GO:0071705 191 0.027
multi organism cellular process GO:0044764 156 0.027
negative regulation of hydrolase activity GO:0051346 182 0.027
guanosine containing compound catabolic process GO:1901069 239 0.026
blastoderm segmentation GO:0007350 2 0.026
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.026
purine containing compound catabolic process GO:0072523 411 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
microtubule cytoskeleton organization GO:0000226 176 0.025
mrna processing GO:0006397 133 0.025
regulation of protein processing GO:0070613 150 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
protein deubiquitination GO:0016579 79 0.024
positive regulation of programmed cell death GO:0043068 249 0.024
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
negative regulation of proteolysis GO:0045861 132 0.024
protein localization to organelle GO:0033365 280 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
reproductive process GO:0022414 106 0.023
Worm
cell aging GO:0007569 52 0.023
mrna metabolic process GO:0016071 175 0.023
nucleocytoplasmic transport GO:0006913 176 0.022
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.022
regulation of protein maturation GO:1903317 150 0.022
meiotic cell cycle GO:0051321 13 0.022
atp metabolic process GO:0046034 176 0.021
nuclear transport GO:0051169 179 0.021
immune system development GO:0002520 195 0.021
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.021
regulation of intracellular transport GO:0032386 195 0.021
rna catabolic process GO:0006401 71 0.021
secretion by cell GO:0032940 226 0.020
negative regulation of cytoplasmic transport GO:1903650 46 0.020
regulation of rho gtpase activity GO:0032319 66 0.020
locomotory behavior GO:0007626 1 0.020
negative regulation of cell death GO:0060548 345 0.020
anterior posterior axis specification embryo GO:0008595 2 0.019
cell growth GO:0016049 160 0.019
cytokinesis GO:0000910 96 0.019
alcohol metabolic process GO:0006066 114 0.019
regulation of kinase activity GO:0043549 314 0.019
nucleoside catabolic process GO:0009164 408 0.019
meiotic nuclear division GO:0007126 10 0.019
rna splicing GO:0008380 131 0.019
regulation of nucleocytoplasmic transport GO:0046822 98 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
release of cytochrome c from mitochondria GO:0001836 35 0.018
metaphase anaphase transition of cell cycle GO:0044784 21 0.018
viral process GO:0016032 146 0.018
cellular amine metabolic process GO:0044106 41 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.018
regulation of transferase activity GO:0051338 355 0.018
viral life cycle GO:0019058 132 0.018
engulfment of apoptotic cell GO:0043652 2 0.017
negative regulation of protein maturation GO:1903318 142 0.017
posttranscriptional gene silencing GO:0016441 25 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.017
Worm
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
neuromuscular junction development GO:0007528 3 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
regulation of response to external stimulus GO:0032101 222 0.016
rna splicing via transesterification reactions GO:0000375 90 0.016
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
mitotic sister chromatid separation GO:0051306 18 0.016
intracellular protein transport GO:0006886 270 0.016
regulation of mitosis GO:0007088 63 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
embryo development GO:0009790 123 0.016
Worm
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
fertilization GO:0009566 12 0.016
regulation of membrane potential GO:0042391 95 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.015
Worm
regulation of mitotic sister chromatid separation GO:0010965 27 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.015
regulation of viral process GO:0050792 103 0.015
regulation of multi organism process GO:0043900 157 0.015
cellular component morphogenesis GO:0032989 314 0.015
regulation of cell differentiation GO:0045595 393 0.014
response to inorganic substance GO:0010035 127 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
chromosome separation GO:0051304 23 0.014
amine metabolic process GO:0009308 44 0.014
double strand break repair GO:0006302 101 0.014
Mouse
proteasome assembly GO:0043248 7 0.014
vesicle mediated transport GO:0016192 371 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
rna processing GO:0006396 255 0.014
protein dna complex subunit organization GO:0071824 80 0.014
cell part morphogenesis GO:0032990 137 0.014
gonad development GO:0008406 34 0.014
developmental maturation GO:0021700 28 0.013
cytoplasmic transport GO:0016482 379 0.013
regulation of chromosome organization GO:0033044 103 0.013
chromatin modification GO:0016568 298 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
inflammatory response to antigenic stimulus GO:0002437 4 0.013
nucleosome organization GO:0034728 66 0.013
muscle contraction GO:0006936 73 0.013
nervous system development GO:0007399 293 0.013
Fly
establishment of protein localization to organelle GO:0072594 172 0.013
dna packaging GO:0006323 77 0.013
mitotic spindle elongation GO:0000022 4 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
cell cycle checkpoint GO:0000075 117 0.012
recombinational repair GO:0000725 50 0.012
Mouse
male gamete generation GO:0048232 22 0.012
triglyceride metabolic process GO:0006641 23 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
regulation of cell development GO:0060284 161 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
Worm
regulation of nucleotide metabolic process GO:0006140 269 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
spindle organization GO:0007051 53 0.012
replicative cell aging GO:0001302 3 0.012
microtubule based process GO:0007017 210 0.012
maintenance of location GO:0051235 112 0.012
chromatin organization GO:0006325 351 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
Worm
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
dna conformation change GO:0071103 113 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
brain development GO:0007420 97 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.012
dna catabolic process GO:0006308 49 0.011
response to xenobiotic stimulus GO:0009410 30 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
regulation of mitotic sister chromatid segregation GO:0033047 27 0.011
oocyte maturation GO:0001556 1 0.011
multicellular organismal reproductive process GO:0048609 40 0.011
Worm
apoptotic signaling pathway GO:0097190 268 0.011
molting cycle GO:0042303 28 0.011
regulation of cytokine production GO:0001817 232 0.011
gamete generation GO:0007276 25 0.011
Worm
epithelium development GO:0060429 227 0.011
Worm
head development GO:0060322 108 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
lipid biosynthetic process GO:0008610 177 0.011
regulation of binding GO:0051098 111 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
lipid metabolic process GO:0006629 381 0.010
gene silencing by rna GO:0031047 26 0.010
neurological system process GO:0050877 163 0.010
negative regulation of immune system process GO:0002683 136 0.010
chromatin remodeling GO:0006338 55 0.010
regulation of immune response GO:0050776 201 0.010
regulation of peptide transport GO:0090087 62 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010

SHFM1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.056
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013