Homo sapiens

7 known processes

WDR45

WD repeat domain 45

(Aliases: WIPI-4,WDRX1,WIPI4)

WDR45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 50 0.164
cellular ketone metabolic process GO:0042180 80 0.134
cellular amine metabolic process GO:0044106 41 0.125
oxidation reduction process GO:0055114 396 0.108
amine metabolic process GO:0009308 44 0.104
regulation of cellular amino acid metabolic process GO:0006521 6 0.103
regulation of cellular amine metabolic process GO:0033238 11 0.083
cellular macromolecule catabolic process GO:0044265 380 0.080
modification dependent macromolecule catabolic process GO:0043632 212 0.072
autophagy GO:0006914 88 0.069
cellular amino acid metabolic process GO:0006520 116 0.069
modification dependent protein catabolic process GO:0019941 209 0.067
cellular protein catabolic process GO:0044257 261 0.062
positive regulation of cellular amine metabolic process GO:0033240 7 0.061
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.052
protein ubiquitination GO:0016567 314 0.051
multicellular organismal aging GO:0010259 3 0.050
vacuole organization GO:0007033 44 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.045
cellular lipid metabolic process GO:0044255 303 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.043
lipid metabolic process GO:0006629 381 0.041
maintenance of location GO:0051235 112 0.037
response to external biotic stimulus GO:0043207 261 0.035
endosomal transport GO:0016197 129 0.035
positive regulation of synaptic transmission GO:0050806 4 0.034
regulation of transferase activity GO:0051338 355 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
negative regulation of cellular amine metabolic process GO:0033239 3 0.029
response to oxygen containing compound GO:1901700 369 0.027
apoptotic signaling pathway GO:0097190 268 0.027
post embryonic development GO:0009791 2 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
positive regulation of transport GO:0051050 336 0.026
protein modification by small protein conjugation GO:0032446 342 0.025
positive regulation of organelle organization GO:0010638 195 0.024
positive regulation of catabolic process GO:0009896 310 0.024
negative regulation of protein metabolic process GO:0051248 391 0.023
system process GO:0003008 349 0.023
single organism cellular localization GO:1902580 332 0.022
regulation of protein kinase activity GO:0045859 289 0.022
cilium morphogenesis GO:0060271 75 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.021
protein catabolic process GO:0030163 325 0.021
organelle assembly GO:0070925 176 0.021
positive regulation of immune system process GO:0002684 283 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
cellular homeostasis GO:0019725 196 0.020
determination of adult lifespan GO:0008340 2 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
protein localization to organelle GO:0033365 280 0.020
response to oxidative stress GO:0006979 121 0.020
response to biotic stimulus GO:0009607 276 0.020
positive regulation of phosphorylation GO:0042327 394 0.019
divalent inorganic cation transport GO:0072511 158 0.019
negative regulation of cell death GO:0060548 345 0.019
compound eye development GO:0048749 1 0.018
small molecule catabolic process GO:0044282 92 0.018
purine containing compound catabolic process GO:0072523 411 0.018
response to abiotic stimulus GO:0009628 336 0.018
defense response GO:0006952 315 0.018
cation transport GO:0006812 331 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
response to other organism GO:0051707 261 0.017
oogenesis GO:0048477 2 0.017
regulation of homeostatic process GO:0032844 121 0.017
peptidyl serine modification GO:0018209 106 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
regeneration GO:0031099 4 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
membrane organization GO:0061024 292 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
positive regulation of developmental process GO:0051094 314 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
negative regulation of organelle organization GO:0010639 126 0.016
locomotory behavior GO:0007626 1 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
cellular chemical homeostasis GO:0055082 180 0.016
regulation of lipid metabolic process GO:0019216 96 0.016
single organism membrane organization GO:0044802 268 0.015
regulation of proteolysis GO:0030162 293 0.015
cellular response to oxidative stress GO:0034599 85 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
regulation of kinase activity GO:0043549 314 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
regulation of cellular response to stress GO:0080135 244 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.015
developmental programmed cell death GO:0010623 3 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
immune response GO:0006955 307 0.015
positive regulation of cell death GO:0010942 263 0.015
negative regulation of protein modification process GO:0031400 200 0.015
regulation of protein processing GO:0070613 150 0.015
segmentation GO:0035282 4 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
regulation of protein localization GO:0032880 296 0.014
dephosphorylation GO:0016311 209 0.014
response to lipid GO:0033993 206 0.014
chemical homeostasis GO:0048878 306 0.014
head development GO:0060322 108 0.014
regulation of ion transport GO:0043269 189 0.014
regulation of secretion GO:0051046 194 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
vesicle mediated transport GO:0016192 371 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
actin filament based process GO:0030029 224 0.014
regulation of protein transport GO:0051223 213 0.014
myeloid cell differentiation GO:0030099 117 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
regulation of dephosphorylation GO:0035303 96 0.014
neurological system process GO:0050877 163 0.014
peptidyl serine phosphorylation GO:0018105 101 0.014
ion transmembrane transport GO:0034220 338 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
rho protein signal transduction GO:0007266 26 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
cell morphogenesis GO:0000902 296 0.013
erythrocyte development GO:0048821 3 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
cellular component morphogenesis GO:0032989 314 0.013
nucleotide catabolic process GO:0009166 408 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
fatty acid metabolic process GO:0006631 115 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
fatty acid biosynthetic process GO:0006633 46 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
small molecule biosynthetic process GO:0044283 157 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
response to bacterium GO:0009617 144 0.013
monocarboxylic acid biosynthetic process GO:0072330 67 0.013
protein maturation GO:0051604 233 0.013
female gamete generation GO:0007292 2 0.013
nervous system development GO:0007399 293 0.013
mapk cascade GO:0000165 288 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
regulation of peptidyl serine phosphorylation GO:0033135 50 0.013
calcium ion transport GO:0006816 147 0.012
regulation of cytokine production GO:0001817 232 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
positive regulation of kinase activity GO:0033674 204 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
regulation of dna metabolic process GO:0051052 153 0.012
cell growth GO:0016049 160 0.012
regulation of protein complex assembly GO:0043254 147 0.012
regulation of protein catabolic process GO:0042176 155 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
energy derivation by oxidation of organic compounds GO:0015980 43 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
blastoderm segmentation GO:0007350 2 0.012
adult locomotory behavior GO:0008344 1 0.012
cellular response to hormone stimulus GO:0032870 125 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
metal ion transport GO:0030001 272 0.012
alcohol metabolic process GO:0006066 114 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
negative regulation of transferase activity GO:0051348 124 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
somatic muscle development GO:0007525 1 0.012
microtubule based process GO:0007017 210 0.012
negative regulation of cell cycle GO:0045786 193 0.012
protein dephosphorylation GO:0006470 81 0.012
defense response to other organism GO:0098542 129 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
renal water homeostasis GO:0003091 4 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
cellular response to oxygen levels GO:0071453 55 0.011
positive regulation of digestive system process GO:0060456 2 0.011
regulation of system process GO:0044057 101 0.011
response to organic cyclic compound GO:0014070 204 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
protein oligomerization GO:0051259 173 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
cofactor metabolic process GO:0051186 87 0.011
cell projection organization GO:0030030 252 0.011
protein autophosphorylation GO:0046777 123 0.011
macroautophagy GO:0016236 39 0.011
sensory perception of pain GO:0019233 4 0.011
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.011
growth GO:0040007 202 0.011
gtp catabolic process GO:0006184 237 0.011
response to hormone GO:0009725 175 0.011
positive regulation of transferase activity GO:0051347 227 0.011
protein processing GO:0016485 226 0.011
generation of precursor metabolites and energy GO:0006091 68 0.011
cytoplasmic transport GO:0016482 379 0.011
transmembrane transport GO:0055085 399 0.010
secretion GO:0046903 254 0.010
coenzyme metabolic process GO:0006732 65 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.010
cellular ion homeostasis GO:0006873 168 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
nucleoside phosphate catabolic process GO:1901292 412 0.010
purine nucleoside catabolic process GO:0006152 398 0.010
positive regulation of mapk cascade GO:0043410 190 0.010
purine ribonucleotide catabolic process GO:0009154 404 0.010

WDR45 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.055
sensory system disease DOID:0050155 203 0.022
eye and adnexa disease DOID:1492 150 0.022
nervous system disease DOID:863 431 0.022
eye disease DOID:5614 149 0.022
inherited metabolic disorder DOID:655 242 0.020
musculoskeletal system disease DOID:17 223 0.017
central nervous system disease DOID:331 186 0.014
neurodegenerative disease DOID:1289 102 0.014
cancer DOID:162 167 0.011
disease of cellular proliferation DOID:14566 174 0.011
organ system cancer DOID:0050686 164 0.011
lysosomal storage disease DOID:3211 47 0.011
retinal disease DOID:5679 118 0.010