Homo sapiens

0 known processes

GTF2B

general transcription factor IIB

(Aliases: TF2B,TFIIB)

GTF2B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.992
Yeast
dna templated transcription initiation GO:0006352 35 0.839
Yeast Fly
protein dna complex subunit organization GO:0071824 80 0.687
Yeast
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.630
Yeast Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.412
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.343
Yeast
protein dna complex assembly GO:0065004 64 0.286
Yeast
protein acetylation GO:0006473 116 0.276
internal protein amino acid acetylation GO:0006475 101 0.184
determination of adult lifespan GO:0008340 2 0.179
histone modification GO:0016570 251 0.165
dna integration GO:0015074 3 0.160
oogenesis GO:0048477 2 0.158
cellular macromolecular complex assembly GO:0034622 324 0.145
Yeast
mrna metabolic process GO:0016071 175 0.126
covalent chromatin modification GO:0016569 254 0.124
post embryonic development GO:0009791 2 0.118
organophosphate biosynthetic process GO:0090407 163 0.106
internal peptidyl lysine acetylation GO:0018393 97 0.101
embryo development GO:0009790 123 0.099
Worm
response to external biotic stimulus GO:0043207 261 0.097
cellular amine metabolic process GO:0044106 41 0.084
mitotic cell cycle process GO:1903047 286 0.079
histone acetylation GO:0016573 93 0.079
cell development GO:0048468 328 0.079
female gamete generation GO:0007292 2 0.078
negative regulation of protein metabolic process GO:0051248 391 0.067
nucleoside phosphate biosynthetic process GO:1901293 109 0.067
lipid metabolic process GO:0006629 381 0.065
proteasomal protein catabolic process GO:0010498 176 0.063
peptidyl lysine modification GO:0018205 144 0.062
regulation of protein processing GO:0070613 150 0.059
chromatin organization GO:0006325 351 0.058
response to other organism GO:0051707 261 0.057
protein acylation GO:0043543 138 0.057
negative regulation of chromosome organization GO:2001251 48 0.056
carbohydrate derivative biosynthetic process GO:1901137 207 0.055
organonitrogen compound biosynthetic process GO:1901566 200 0.054
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.054
regulation of interferon beta biosynthetic process GO:0045357 4 0.052
mitotic cell cycle GO:0000278 326 0.052
purine nucleoside catabolic process GO:0006152 398 0.052
chromatin modification GO:0016568 298 0.050
rna processing GO:0006396 255 0.050
endocytosis GO:0006897 159 0.050
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.050
purine nucleoside triphosphate catabolic process GO:0009146 392 0.049
nucleoside triphosphate metabolic process GO:0009141 422 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.048
nucleotide biosynthetic process GO:0009165 109 0.047
defense response to bacterium GO:0042742 63 0.047
purine nucleotide catabolic process GO:0006195 405 0.047
transcription from rna polymerase iii promoter GO:0006383 19 0.046
organophosphate catabolic process GO:0046434 430 0.046
negative regulation of apoptotic process GO:0043066 316 0.046
reactive oxygen species metabolic process GO:0072593 75 0.045
ribonucleotide catabolic process GO:0009261 405 0.045
regulation of cellular component biogenesis GO:0044087 281 0.044
regulation of cellular ketone metabolic process GO:0010565 50 0.044
negative regulation of programmed cell death GO:0043069 321 0.043
response to biotic stimulus GO:0009607 276 0.043
immune response GO:0006955 307 0.042
neurogenesis GO:0022008 169 0.042
glycosyl compound catabolic process GO:1901658 413 0.041
glycoprotein metabolic process GO:0009100 110 0.040
neuron projection development GO:0031175 106 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.040
positive regulation of programmed cell death GO:0043068 249 0.038
microtubule cytoskeleton organization GO:0000226 176 0.038
cyclic purine nucleotide metabolic process GO:0052652 60 0.038
negative regulation of transferase activity GO:0051348 124 0.037
response to bacterium GO:0009617 144 0.036
amine metabolic process GO:0009308 44 0.036
rna splicing GO:0008380 131 0.036
blastocyst development GO:0001824 3 0.035
establishment of protein localization to organelle GO:0072594 172 0.034
multicellular organismal aging GO:0010259 3 0.034
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
lipid biosynthetic process GO:0008610 177 0.032
regulation of cytokine production GO:0001817 232 0.031
microtubule based process GO:0007017 210 0.030
dna templated transcription elongation GO:0006354 25 0.030
nucleoside catabolic process GO:0009164 408 0.030
negative regulation of cell cycle GO:0045786 193 0.029
protein catabolic process GO:0030163 325 0.029
response to cytokine GO:0034097 232 0.028
purine containing compound catabolic process GO:0072523 411 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
glycosylation GO:0070085 71 0.027
positive regulation of cell death GO:0010942 263 0.027
innate immune response GO:0045087 178 0.027
regulation of kinase activity GO:0043549 314 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
gtp metabolic process GO:0046039 239 0.026
rna capping GO:0036260 10 0.026
positive regulation of apoptotic process GO:0043065 246 0.026
macromolecule glycosylation GO:0043413 63 0.026
peptidyl lysine acetylation GO:0018394 101 0.026
negative regulation of protein kinase activity GO:0006469 98 0.025
nervous system development GO:0007399 293 0.025
neuroblast proliferation GO:0007405 4 0.025
protein glycosylation GO:0006486 62 0.025
regulation of transferase activity GO:0051338 355 0.025
positive regulation of transport GO:0051050 336 0.025
negative regulation of phosphorylation GO:0042326 174 0.025
mrna splicing via spliceosome GO:0000398 89 0.025
neuron remodeling GO:0016322 2 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.024
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.023
negative regulation of cell death GO:0060548 345 0.023
transmembrane transport GO:0055085 399 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
regulation of chromatin organization GO:1902275 56 0.023
methylation GO:0032259 106 0.023
intracellular protein transport GO:0006886 270 0.022
single organism cellular localization GO:1902580 332 0.022
positive regulation of cell proliferation GO:0008284 301 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
mrna processing GO:0006397 133 0.022
nucleotide catabolic process GO:0009166 408 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
receptor mediated endocytosis GO:0006898 84 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
single organism reproductive process GO:0044702 98 0.021
interspecies interaction between organisms GO:0044419 156 0.021
regulation of cell cycle GO:0051726 393 0.020
chromatin assembly GO:0031497 61 0.020
vesicle mediated transport GO:0016192 371 0.020
regulation of reactive oxygen species metabolic process GO:2000377 41 0.020
growth GO:0040007 202 0.020
cilium organization GO:0044782 68 0.020
reproduction GO:0000003 63 0.020
carbohydrate metabolic process GO:0005975 207 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.019
regulation of cell growth GO:0001558 135 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
nuclear division GO:0000280 128 0.019
guanosine containing compound metabolic process GO:1901068 244 0.019
maintenance of location GO:0051235 112 0.018
negative regulation of protein phosphorylation GO:0001933 140 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
epithelium development GO:0060429 227 0.018
response to radiation GO:0009314 151 0.018
inner ear morphogenesis GO:0042472 4 0.018
de novo protein folding GO:0006458 2 0.018
negative regulation of catalytic activity GO:0043086 335 0.017
response to glucagon GO:0033762 1 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
regulation of protein maturation GO:1903317 150 0.017
cellular protein catabolic process GO:0044257 261 0.017
single organism membrane organization GO:0044802 268 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
response to tumor necrosis factor GO:0034612 76 0.017
regulation of rna splicing GO:0043484 62 0.017
regulation of protein stability GO:0031647 87 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
gtp catabolic process GO:0006184 237 0.017
glycerolipid metabolic process GO:0046486 107 0.017
myoblast fusion GO:0007520 1 0.017
neuron differentiation GO:0030182 138 0.017
lipid localization GO:0010876 106 0.017
spermatid differentiation GO:0048515 4 0.016
dna packaging GO:0006323 77 0.016
apoptotic signaling pathway GO:0097190 268 0.016
meiotic chromosome segregation GO:0045132 4 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
cellular lipid metabolic process GO:0044255 303 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
regulation of chromatin modification GO:1903308 51 0.016
reproductive process GO:0022414 106 0.016
organic hydroxy compound metabolic process GO:1901615 147 0.016
chemical homeostasis GO:0048878 306 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.015
regulation of immune response GO:0050776 201 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.015
cytoplasmic transport GO:0016482 379 0.015
positive regulation of immune response GO:0050778 159 0.015
protein processing GO:0016485 226 0.015
blood vessel development GO:0001568 172 0.015
response to drug GO:0042493 81 0.015
phospholipid metabolic process GO:0006644 99 0.015
positive regulation of immune system process GO:0002684 283 0.015
negative regulation of growth GO:0045926 97 0.015
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.015
small molecule biosynthetic process GO:0044283 157 0.015
regulation of intracellular transport GO:0032386 195 0.015
mitochondrial transport GO:0006839 60 0.014
purine containing compound biosynthetic process GO:0072522 88 0.014
regulation of gtpase activity GO:0043087 180 0.014
transcription from rna polymerase i promoter GO:0006360 11 0.014
jak stat cascade GO:0007259 46 0.014
positive regulation of catabolic process GO:0009896 310 0.014
cell projection organization GO:0030030 252 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
cell growth GO:0016049 160 0.014
regulation of cellular response to stress GO:0080135 244 0.014
segmentation GO:0035282 4 0.014
response to abiotic stimulus GO:0009628 336 0.014
regulation of protein kinase activity GO:0045859 289 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
secretory granule organization GO:0033363 2 0.014
protein stabilization GO:0050821 64 0.014
alcohol metabolic process GO:0006066 114 0.014
positive regulation of organelle organization GO:0010638 195 0.014
histone h3 acetylation GO:0043966 45 0.014
lipid transport GO:0006869 90 0.013
cell morphogenesis GO:0000902 296 0.013
glycerolipid biosynthetic process GO:0045017 51 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
response to acid chemical GO:0001101 66 0.013
defense response GO:0006952 315 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
regulation of mrna processing GO:0050684 48 0.013
epithelial cell differentiation GO:0030855 141 0.013
embryo development ending in birth or egg hatching GO:0009792 34 0.013
Worm
retrograde transport endosome to golgi GO:0042147 45 0.013
endomembrane system organization GO:0010256 196 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
signal transduction by p53 class mediator GO:0072331 72 0.013
aging GO:0007568 66 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
phosphatidic acid biosynthetic process GO:0006654 4 0.013
spermatid development GO:0007286 4 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
regulation of neurogenesis GO:0050767 82 0.012
positive regulation of dendrite morphogenesis GO:0050775 3 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
dna damage response detection of dna damage GO:0042769 3 0.012
nucleosome organization GO:0034728 66 0.012
negative regulation of organelle organization GO:0010639 126 0.012
response to nitrogen compound GO:1901698 184 0.012
steroid metabolic process GO:0008202 94 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
spindle elongation GO:0051231 4 0.012
regulation of autophagy GO:0010506 52 0.012
protein import GO:0017038 130 0.012
positive regulation of developmental process GO:0051094 314 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
protein localization to organelle GO:0033365 280 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
cellular response to external stimulus GO:0071496 111 0.011
regulation of mrna splicing via spliceosome GO:0048024 32 0.011
regulation of protein localization GO:0032880 296 0.011
cell projection morphogenesis GO:0048858 129 0.011
dna replication dependent nucleosome assembly GO:0006335 32 0.011
negative regulation of protein modification process GO:0031400 200 0.011
generation of neurons GO:0048699 152 0.011
vasculature development GO:0001944 181 0.011
tripartite regional subdivision GO:0007351 2 0.011
toxin transport GO:1901998 4 0.011
dna repair GO:0006281 198 0.011
vasodilation GO:0042311 4 0.011
regulation of body fluid levels GO:0050878 99 0.011
chromatin assembly or disassembly GO:0006333 78 0.011
positive regulation of cytokine production GO:0001819 167 0.011
cellular ketone metabolic process GO:0042180 80 0.011
positive regulation of exocytosis GO:0045921 35 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
anterior posterior axis specification GO:0009948 2 0.011
regulation of cytokine biosynthetic process GO:0042035 35 0.011
translation GO:0006412 132 0.011
somatic muscle development GO:0007525 1 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.010
peptide transport GO:0015833 74 0.010
ribonucleoprotein complex assembly GO:0022618 78 0.010
cerebellum development GO:0021549 2 0.010
cyclic nucleotide biosynthetic process GO:0009190 61 0.010
neuron development GO:0048666 113 0.010
establishment of protein localization to mitochondrion GO:0072655 22 0.010
negative regulation of kinase activity GO:0033673 106 0.010
cell part morphogenesis GO:0032990 137 0.010
protein modification by small protein conjugation GO:0032446 342 0.010
axon cargo transport GO:0008088 2 0.010
negative regulation of cell differentiation GO:0045596 171 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
response to oxygen containing compound GO:1901700 369 0.010
anion transport GO:0006820 161 0.010
negative regulation of cell growth GO:0030308 83 0.010
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010

GTF2B disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.040
disease of cellular proliferation DOID:14566 174 0.040
disease of metabolism DOID:0014667 295 0.027
organ system cancer DOID:0050686 164 0.024
amino acid metabolic disorder DOID:9252 50 0.019
inherited metabolic disorder DOID:655 242 0.019