|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
1.000
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.999
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.988
|
Mouse Rat |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.985
|
|
|
|
regulation of interleukin 6 mediated signaling pathway
|
GO:0070103 |
3 |
0.979
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.978
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
3 |
0.973
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.968
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.965
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.959
|
Mouse Rat |
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.955
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.952
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.947
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.946
|
Mouse |
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.944
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.929
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.927
|
Mouse Rat |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.923
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.912
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.911
|
Mouse Rat |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.911
|
Mouse Rat Fly |
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.910
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.907
|
Rat |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.907
|
Rat |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.906
|
Mouse |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.905
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.896
|
Rat |
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.896
|
Mouse |
|
|
ciliary neurotrophic factor mediated signaling pathway
|
GO:0070120 |
5 |
0.894
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.889
|
Rat |
|
|
innate immune response
|
GO:0045087 |
178 |
0.884
|
Rat |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.881
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.876
|
Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.858
|
Rat |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.844
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.840
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.805
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.800
|
Mouse Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.795
|
Mouse Rat |
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
3 |
0.789
|
Human |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.788
|
Rat |
|
|
leukemia inhibitory factor signaling pathway
|
GO:0048861 |
3 |
0.779
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.777
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.768
|
Mouse Fly |
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
2 |
0.767
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
11 |
0.752
|
Rat |
|
|
immune effector process
|
GO:0002252 |
159 |
0.751
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.750
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.739
|
Rat |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.737
|
Mouse Rat |
|
|
response to estradiol
|
GO:0032355 |
23 |
0.734
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.734
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.733
|
Mouse |
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.726
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.715
|
Mouse Rat |
|
|
oncostatin m mediated signaling pathway
|
GO:0038165 |
3 |
0.710
|
|
|
|
mating
|
GO:0007618 |
1 |
0.708
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.695
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.693
|
Mouse Fly |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.686
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.680
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.671
|
Mouse Rat |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.668
|
Rat |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.662
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.661
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.661
|
Rat |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.646
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.640
|
Mouse |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.639
|
Rat |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.627
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.625
|
Rat |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.609
|
Rat |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.609
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.602
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.596
|
Rat |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.582
|
|
|
|
positive regulation of mitosis
|
GO:0045840 |
25 |
0.575
|
|
|
|
branched chain amino acid metabolic process
|
GO:0009081 |
4 |
0.575
|
|
|
|
response to interleukin 15
|
GO:0070672 |
6 |
0.572
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.572
|
Mouse Rat |
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
1 |
0.569
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.566
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.563
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.555
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.554
|
Mouse Rat |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.551
|
Rat |
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.549
|
Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.546
|
Rat |
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.534
|
Mouse Rat |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.533
|
Rat |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.533
|
Rat |
|
|
response to estrogen
|
GO:0043627 |
47 |
0.523
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.515
|
Rat |
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.506
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.501
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
7 |
0.499
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.499
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
2 |
0.495
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.493
|
Rat |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.491
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.484
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.484
|
|
|
|
negative regulation of interleukin 6 mediated signaling pathway
|
GO:0070104 |
2 |
0.472
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.468
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.466
|
Mouse Rat |
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
2 |
0.460
|
Mouse Rat |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.457
|
Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.455
|
|
|
|
taurine metabolic process
|
GO:0019530 |
1 |
0.431
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.428
|
|
|
|
succinate metabolic process
|
GO:0006105 |
1 |
0.427
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.425
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.424
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.420
|
Fly |
|
|
stem cell division
|
GO:0017145 |
2 |
0.419
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.418
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.416
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.412
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
8 |
0.410
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.393
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.392
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.388
|
|
|
|
oxaloacetate metabolic process
|
GO:0006107 |
1 |
0.383
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.374
|
Mouse Fly |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.370
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.370
|
Rat |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.368
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.363
|
Mouse |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.358
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.352
|
Rat Fly |
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.352
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.345
|
Mouse Fly |
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.338
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.336
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.336
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.332
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.328
|
Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.324
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.323
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.317
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.316
|
Rat |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.316
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.311
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.305
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.304
|
Mouse Rat |
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.302
|
Rat |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.301
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.299
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.298
|
Mouse Fly |
|
|
cellular lactam metabolic process
|
GO:0072338 |
1 |
0.296
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.295
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.293
|
Fly |
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.291
|
Mouse |
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.283
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.283
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.281
|
Mouse |
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.277
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.273
|
Rat |
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.272
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.271
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.265
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.258
|
Mouse Rat |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.257
|
Mouse Rat |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.255
|
Rat |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.249
|
Mouse |
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.248
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.245
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.244
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.241
|
Rat |
|
|
response to interleukin 4
|
GO:0070670 |
7 |
0.240
|
Human |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.236
|
Fly |
|
|
natural killer cell differentiation
|
GO:0001779 |
2 |
0.235
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.233
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.232
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.232
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.230
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.230
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.224
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.219
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.219
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.217
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.215
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.214
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.212
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.212
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.211
|
Rat |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.211
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.210
|
Rat |
|
|
response to virus
|
GO:0009615 |
126 |
0.208
|
Fly |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.208
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.207
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.204
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.204
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.204
|
Mouse Fly |
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.200
|
|
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
4 |
0.199
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.199
|
Mouse Rat |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.199
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.197
|
Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.195
|
Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.195
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.194
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.191
|
Mouse Rat |
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.189
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
1 |
0.185
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.185
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.183
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.180
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.179
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.175
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.175
|
Mouse |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.174
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.173
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.172
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.171
|
Fly |
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
8 |
0.170
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.169
|
|
|
|
growth
|
GO:0040007 |
202 |
0.169
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.167
|
Mouse |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.166
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.166
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.165
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.161
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.161
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.158
|
Mouse Rat |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.157
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.155
|
Mouse Rat |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.154
|
Rat |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.154
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.154
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.153
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.153
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.152
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.152
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.151
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.149
|
Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.148
|
Mouse Rat |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.148
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.148
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.147
|
Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.146
|
Rat |
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.145
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.144
|
Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.140
|
Rat |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.139
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.139
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.136
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.135
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.135
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.134
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.132
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.132
|
Mouse Rat |
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.132
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.132
|
Rat |
|
|
response to radiation
|
GO:0009314 |
151 |
0.131
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.131
|
Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.130
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.129
|
Mouse |
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.129
|
Rat |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.129
|
Rat Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.128
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.128
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.128
|
Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.128
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.126
|
Rat |
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.126
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.125
|
|
|
|
regulation of cardiac muscle cell apoptotic process
|
GO:0010665 |
3 |
0.125
|
Rat |
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
5 |
0.125
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.123
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.123
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.122
|
Rat |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.122
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.121
|
Mouse Rat |
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.120
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.119
|
Rat |
|
|
response to other organism
|
GO:0051707 |
261 |
0.119
|
Mouse Fly |
|
|
citrate metabolic process
|
GO:0006101 |
2 |
0.119
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.119
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.118
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.118
|
Rat |
|
|
cell activation
|
GO:0001775 |
213 |
0.118
|
Rat |
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.115
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.115
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.114
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.114
|
Rat Fly |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.113
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.113
|
Rat |
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.113
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.111
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.110
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.110
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.110
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.108
|
Rat |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.107
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.106
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.105
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.105
|
|
|
|
response to food
|
GO:0032094 |
1 |
0.104
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.103
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.103
|
Mouse Rat |
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.103
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.102
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.101
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.101
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.101
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.100
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.100
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.099
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.098
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.098
|
Rat |
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.098
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.097
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.097
|
Fly |
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.097
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.095
|
Mouse |
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.094
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.094
|
Fly |
|
|
protein import
|
GO:0017038 |
130 |
0.094
|
Mouse Rat |
|
|
interleukin 12 mediated signaling pathway
|
GO:0035722 |
3 |
0.094
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.094
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.094
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.093
|
Mouse |
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
1 |
0.093
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.093
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.093
|
Rat |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.093
|
|
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.092
|
|
|
|
positive regulation of muscle cell apoptotic process
|
GO:0010661 |
4 |
0.092
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.092
|
Mouse Rat |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.091
|
Mouse Rat |
|
|
lipid localization
|
GO:0010876 |
106 |
0.091
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.091
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.091
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.091
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.091
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.091
|
|
|
|
negative regulation of hydrogen peroxide metabolic process
|
GO:0010727 |
3 |
0.088
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
3 |
0.088
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.087
|
|
|
|
b cell differentiation
|
GO:0030183 |
6 |
0.087
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.087
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.087
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.086
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.086
|
Mouse Rat |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.086
|
Fly |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.085
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.085
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.084
|
Rat |
|
|
associative learning
|
GO:0008306 |
1 |
0.084
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.084
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.084
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.084
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.084
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.083
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.083
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.083
|
Mouse |
|
|
segmentation
|
GO:0035282 |
4 |
0.082
|
Fly |
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.082
|
|
|
|
negative regulation of type i interferon mediated signaling pathway
|
GO:0060339 |
4 |
0.082
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.081
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.081
|
Fly |
|
|
negative regulation of endothelial cell proliferation
|
GO:0001937 |
20 |
0.081
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.081
|
Rat |
|
|
protein targeting
|
GO:0006605 |
187 |
0.080
|
Mouse Rat |
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.078
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.078
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.077
|
Rat |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.076
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.076
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.076
|
Rat |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.075
|
Rat |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.074
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.073
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.073
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.073
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.073
|
Fly |
|
|
rhythmic process
|
GO:0048511 |
31 |
0.072
|
Fly |
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.072
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.072
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.072
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.072
|
Rat |
|
|
regulation of activation of janus kinase activity
|
GO:0010533 |
6 |
0.072
|
|
|
|
regulation of response to osmotic stress
|
GO:0047484 |
3 |
0.071
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.071
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.070
|
Fly |
|
|
neuron death
|
GO:0070997 |
65 |
0.070
|
Rat |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.070
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.070
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.070
|
Rat Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.069
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.069
|
Rat |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.069
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.068
|
Rat Fly |
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.068
|
Fly |
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.067
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.067
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.067
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.066
|
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.066
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.065
|
Mouse Rat |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.065
|
Mouse Rat |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.064
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.063
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
8 |
0.063
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.063
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.063
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.063
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.062
|
Rat |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.061
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.061
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.061
|
|
|
|
natural killer cell activation
|
GO:0030101 |
12 |
0.061
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.061
|
|
|
|
negative regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030948 |
3 |
0.061
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.060
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
6 |
0.060
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.060
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.060
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.059
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.059
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.059
|
Fly |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.058
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.058
|
Mouse |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.057
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.057
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.057
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
6 |
0.057
|
Human |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.057
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.057
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.056
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.056
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.056
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.056
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.056
|
|
|
|
positive regulation of cellular response to insulin stimulus
|
GO:1900078 |
6 |
0.056
|
|
|
|
negative regulation of response to interferon gamma
|
GO:0060331 |
2 |
0.056
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.055
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.055
|
|
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
3 |
0.055
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.055
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.055
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.055
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.054
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.054
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.054
|
Fly |
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.053
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.053
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.053
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.053
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.053
|
Rat |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.053
|
Mouse Rat |
|
|
dicarboxylic acid metabolic process
|
GO:0043648 |
29 |
0.052
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.052
|
Mouse Rat |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.051
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.051
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.051
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.050
|
Rat |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.050
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.050
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.050
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.049
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.049
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.049
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.048
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.047
|
|
|
|
response to ph
|
GO:0009268 |
12 |
0.047
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.047
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.047
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.046
|
Rat |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.046
|
Mouse |
|
|
defense response to virus
|
GO:0051607 |
71 |
0.046
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.045
|
Rat |
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.045
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.045
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.045
|
Fly |
|
|
macrophage fusion
|
GO:0034238 |
1 |
0.045
|
|
|
|
memory
|
GO:0007613 |
3 |
0.045
|
Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.045
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.045
|
Fly |
|
|
organelle fission
|
GO:0048285 |
149 |
0.044
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.044
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.044
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.044
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.044
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.044
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.043
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.043
|
Rat |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.043
|
|
