|
|
ciliary neurotrophic factor mediated signaling pathway
|
GO:0070120 |
5 |
1.000
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.995
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.961
|
|
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.933
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.932
|
Human |
|
|
leukemia inhibitory factor signaling pathway
|
GO:0048861 |
3 |
0.921
|
|
|
|
oncostatin m mediated signaling pathway
|
GO:0038165 |
3 |
0.893
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.872
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
3 |
0.867
|
Human |
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.864
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.847
|
|
|
|
regulation of interleukin 6 mediated signaling pathway
|
GO:0070103 |
3 |
0.818
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.785
|
|
|
|
negative regulation of cytosolic calcium ion concentration
|
GO:0051481 |
1 |
0.623
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.618
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.577
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.563
|
|
|
|
negative regulation of multicellular organismal metabolic process
|
GO:0044252 |
3 |
0.563
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.538
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.536
|
Human Mouse |
|
|
cellular response to type i interferon
|
GO:0071357 |
12 |
0.515
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.507
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
2 |
0.501
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.491
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.480
|
|
|
|
positive regulation of toll like receptor 4 signaling pathway
|
GO:0034145 |
6 |
0.469
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.443
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.439
|
Human |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.428
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.426
|
Zebrafish |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.420
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.413
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.395
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.390
|
Fly |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.384
|
Fly |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.383
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.376
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.374
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.355
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.340
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.338
|
Fly |
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.334
|
Human |
|
|
renal tubule development
|
GO:0061326 |
19 |
0.332
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.331
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.328
|
Human Fly |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.326
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.319
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.311
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.308
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.303
|
|
|
|
regulation of skeletal muscle cell proliferation
|
GO:0014857 |
1 |
0.302
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.299
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.292
|
Human |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.290
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.277
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.274
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.272
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.263
|
Fly |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.260
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.259
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.259
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.256
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.251
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.250
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.247
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.247
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
28 |
0.246
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.245
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.239
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.238
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.230
|
Fly |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.228
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.228
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.226
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.224
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
2 |
0.222
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.221
|
Fly |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.216
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.212
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.211
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.211
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.211
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.210
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.202
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.201
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.194
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.190
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.188
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.188
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.187
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.184
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.182
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.180
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.177
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.175
|
Fly |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.171
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.168
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.168
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.167
|
Fly |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.158
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.156
|
|
|
|
positive regulation of toll like receptor 2 signaling pathway
|
GO:0034137 |
2 |
0.154
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.152
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.150
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.150
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.148
|
Human |
|
|
growth
|
GO:0040007 |
202 |
0.144
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.141
|
Fly |
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.139
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.139
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.138
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.137
|
|
|
|
negative regulation of interleukin 6 mediated signaling pathway
|
GO:0070104 |
2 |
0.134
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.133
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.131
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.131
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.131
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.130
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.130
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.128
|
Fly |
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.126
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.123
|
Fly |
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.123
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.123
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.122
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.121
|
Human |
|
|
response to interferon beta
|
GO:0035456 |
11 |
0.120
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.120
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.119
|
Fly |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.117
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.116
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.114
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.114
|
|
|
|
regulation of satellite cell proliferation
|
GO:0014842 |
1 |
0.113
|
|
|
|
macrophage fusion
|
GO:0034238 |
1 |
0.113
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.112
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.112
|
Fly |
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.111
|
Zebrafish |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.111
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.111
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.108
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.108
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.107
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.106
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.106
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.106
|
|
|
|
negative regulation of collagen metabolic process
|
GO:0010713 |
3 |
0.105
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.102
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.100
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.098
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.097
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.096
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.096
|
Human |
|
|
skeletal muscle cell proliferation
|
GO:0014856 |
1 |
0.096
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.095
|
|
|
|
cellular response to bacterial lipoprotein
|
GO:0071220 |
3 |
0.095
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
23 |
0.092
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.091
|
|
|
|
negative regulation of hydrogen peroxide metabolic process
|
GO:0010727 |
3 |
0.091
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.090
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.090
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.090
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.089
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.088
|
Fly |
|
|
protein processing
|
GO:0016485 |
226 |
0.088
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.087
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.087
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.087
|
Fly |
|
|
axon regeneration
|
GO:0031103 |
1 |
0.087
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.086
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.085
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.085
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.083
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
1 |
0.082
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.082
|
Fly |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.082
|
|
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.081
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.081
|
|
|
|
mammary gland involution
|
GO:0060056 |
1 |
0.080
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.080
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.079
|
Fly |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.078
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
2 |
0.078
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.078
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.077
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.077
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.077
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.076
|
Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.076
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.076
|
|
|
|
response to type i interferon
|
GO:0034340 |
14 |
0.076
|
|
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.076
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.076
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.074
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.073
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.073
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.072
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.072
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.071
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.070
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.070
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.070
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.069
|
Human |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.069
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.068
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.068
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.067
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.067
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.066
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.066
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.066
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.066
|
|
|
|
response to interferon alpha
|
GO:0035455 |
11 |
0.066
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.066
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.066
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.066
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.066
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.065
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.065
|
|
|
|
skeletal muscle satellite cell proliferation
|
GO:0014841 |
1 |
0.064
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
1 |
0.064
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.063
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.063
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.063
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.063
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.062
|
Fly |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.062
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.062
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.062
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.062
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.062
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
2 |
0.061
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.061
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.061
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.061
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.061
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.060
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.060
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.060
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.060
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.060
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.059
|
Fly |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.059
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.059
|
Zebrafish |
|
|
response to axon injury
|
GO:0048678 |
1 |
0.059
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.058
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.057
|
Fly |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.056
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.056
|
Zebrafish Fly |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.056
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.056
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.056
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.055
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.055
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.055
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.054
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.054
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.053
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.053
|
Human |
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.052
|
|
|
|
positive regulation of toll like receptor 3 signaling pathway
|
GO:0034141 |
1 |
0.052
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.052
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.052
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.051
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.051
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.051
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.051
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.050
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.050
|
Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.050
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.049
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.049
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.049
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.049
|
Zebrafish Fly |
|
|
negative regulation of endothelial cell proliferation
|
GO:0001937 |
20 |
0.049
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.049
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.049
|
|
|
|
regulation of exosomal secretion
|
GO:1903541 |
12 |
0.048
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.048
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.048
|
Zebrafish Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.048
|
Fly |
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.048
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.047
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.047
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.046
|
Fly |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.046
|
Fly |
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.046
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.046
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.046
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.046
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.046
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.046
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.045
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.045
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.044
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.044
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.044
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.044
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.044
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.043
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.043
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.043
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.043
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.043
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.043
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.043
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.043
|
Fly |
|
|
response to lipoteichoic acid
|
GO:0070391 |
3 |
0.042
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.042
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.042
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.042
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.042
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.042
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.041
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.041
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
3 |
0.041
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.041
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.041
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.041
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.040
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
11 |
0.040
|
|
|
|
hydrogen peroxide metabolic process
|
GO:0042743 |
20 |
0.040
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.040
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.039
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.038
|
Human |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.038
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.038
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.038
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.038
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.038
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.038
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.037
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
21 |
0.037
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.037
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.037
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.037
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.037
|
|
|
|
monocyte differentiation
|
GO:0030224 |
15 |
0.037
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.037
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.037
|
Fly |
|
|
signal release
|
GO:0023061 |
70 |
0.037
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.036
|
|
|
|
citrate metabolic process
|
GO:0006101 |
2 |
0.036
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.036
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.036
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.036
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.036
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.036
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.036
|
Fly |
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.036
|
|
|
|
positive regulation of exosomal secretion
|
GO:1903543 |
12 |
0.036
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.036
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.035
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.035
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.035
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.035
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.035
|
|
|
|
cellular response to lipoteichoic acid
|
GO:0071223 |
3 |
0.035
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.035
|
Human |
|
|
regulation of macrophage fusion
|
GO:0034239 |
1 |
0.035
|
|
|
|
erythrocyte development
|
GO:0048821 |
3 |
0.034
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.034
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.034
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.034
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.034
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.034
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.034
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.034
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.034
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.033
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.032
|
Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.032
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.032
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.032
|
Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.032
|
Fly |
|
|
memory
|
GO:0007613 |
3 |
0.032
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.032
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.031
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.031
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.031
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.031
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.031
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.031
|
Fly |
|
|
cellular response to bacterial lipopeptide
|
GO:0071221 |
3 |
0.031
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.031
|
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.031
|
Human |
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.030
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.030
|
Fly |
|
|
response to bacterial lipoprotein
|
GO:0032493 |
3 |
0.030
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
1 |
0.030
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.030
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.030
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.029
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.029
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.029
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.029
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.029
|
Fly |
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.029
|
Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.029
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.029
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.029
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.028
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.028
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.028
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.028
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.028
|
|
|
|
response to ethanol
|
GO:0045471 |
11 |
0.028
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.028
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.028
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.028
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.027
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.027
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.027
|
Fly |
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.027
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.027
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
1 |
0.027
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.027
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.027
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.027
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.027
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.027
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.027
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.026
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.026
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.026
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.026
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.026
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.026
|
|
|
|
branched chain amino acid metabolic process
|
GO:0009081 |
4 |
0.026
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.026
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.026
|
Fly |
|
|
negative regulation of neuron migration
|
GO:2001223 |
1 |
0.025
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.025
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.025
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.025
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.025
|
Fly |
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.025
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.025
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.025
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.025
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.025
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.025
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.025
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.025
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.025
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.025
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.024
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
14 |
0.024
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.024
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.024
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.024
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.024
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.024
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.024
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.024
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.024
|
|
|
|
acute phase response
|
GO:0006953 |
5 |
0.024
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.024
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.024
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.024
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.024
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.023
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.023
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.023
|
Fly |
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.023
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.023
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
1 |
0.023
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.023
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.023
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.023
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.023
|
Human |
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.022
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.022
|
Zebrafish |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.022
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.022
|
Human |
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.022
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.022
|
|
|
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
GO:0045743 |
3 |
0.022
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.022
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.022
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.022
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.022
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.022
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.022
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.022
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.021
|
Human |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.021
|
|
