Homo sapiens

18 known processes

EIF2S1

eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

(Aliases: EIF-2A,EIF2,EIF-2,EIF-2alpha,EIF2A)

EIF2S1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.958
ncrna metabolic process GO:0034660 108 0.957
ncrna processing GO:0034470 83 0.913
posttranscriptional regulation of gene expression GO:0010608 213 0.827
Mouse
translation GO:0006412 132 0.809
translational initiation GO:0006413 48 0.727
determination of adult lifespan GO:0008340 2 0.699
ribonucleoprotein complex biogenesis GO:0022613 116 0.678
Yeast
multicellular organismal aging GO:0010259 3 0.662
rrna metabolic process GO:0016072 40 0.657
vesicle mediated transport GO:0016192 371 0.472
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.447
rna processing GO:0006396 255 0.349
chordate embryonic development GO:0043009 34 0.347
regulation of translation GO:0006417 89 0.267
Mouse
embryo development GO:0009790 123 0.244
cellular response to dna damage stimulus GO:0006974 379 0.218
growth GO:0040007 202 0.217
reproduction GO:0000003 63 0.198
receptor mediated endocytosis GO:0006898 84 0.185
regulation of protein localization GO:0032880 296 0.174
cellular macromolecular complex assembly GO:0034622 324 0.170
Yeast
reproductive process GO:0022414 106 0.170
embryo development ending in birth or egg hatching GO:0009792 34 0.165
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.159
nervous system development GO:0007399 293 0.146
ribosome biogenesis GO:0042254 48 0.141
reproductive structure development GO:0048608 55 0.138
reproductive system development GO:0061458 56 0.128
rrna processing GO:0006364 35 0.125
ossification GO:0001503 121 0.125
regulation of intracellular transport GO:0032386 195 0.103
ribonucleoprotein complex assembly GO:0022618 78 0.102
Yeast
developmental process involved in reproduction GO:0003006 66 0.102
aging GO:0007568 66 0.099
female gamete generation GO:0007292 2 0.093
oogenesis GO:0048477 2 0.092
cellular macromolecule catabolic process GO:0044265 380 0.087
regulation of protein targeting GO:1903533 91 0.081
regulation of translational initiation GO:0006446 24 0.079
Mouse
cell development GO:0048468 328 0.079
gonad development GO:0008406 34 0.079
posttranscriptional gene silencing by rna GO:0035194 25 0.078
guanosine containing compound catabolic process GO:1901069 239 0.072
endocytosis GO:0006897 159 0.071
regulation of nucleocytoplasmic transport GO:0046822 98 0.070
positive regulation of intracellular protein transport GO:0090316 76 0.070
rna catabolic process GO:0006401 71 0.069
regulation of growth GO:0040008 165 0.068
regulation of intracellular protein transport GO:0033157 123 0.065
gene silencing by rna GO:0031047 26 0.065
mrna metabolic process GO:0016071 175 0.063
cellular amino acid metabolic process GO:0006520 116 0.062
rna phosphodiester bond hydrolysis GO:0090501 35 0.058
maturation of ssu rrna GO:0030490 3 0.058
multicellular organism reproduction GO:0032504 42 0.056
gene silencing GO:0016458 49 0.056
protein targeting GO:0006605 187 0.056
negative regulation of cell proliferation GO:0008285 228 0.056
organelle fission GO:0048285 149 0.056
positive regulation of developmental process GO:0051094 314 0.055
rna interference GO:0016246 4 0.053
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.053
multicellular organismal reproductive process GO:0048609 40 0.051
single organism cellular localization GO:1902580 332 0.050
regulation of protein localization to nucleus GO:1900180 85 0.048
neurological system process GO:0050877 163 0.048
protein targeting to nucleus GO:0044744 104 0.047
purine ribonucleoside catabolic process GO:0046130 398 0.043
positive regulation of cytoplasmic transport GO:1903651 82 0.042
regeneration GO:0031099 4 0.040
positive regulation of catabolic process GO:0009896 310 0.039
establishment of protein localization to organelle GO:0072594 172 0.039
response to dsrna GO:0043331 25 0.038
protein import GO:0017038 130 0.038
oocyte differentiation GO:0009994 2 0.037
nucleotide catabolic process GO:0009166 408 0.037
central nervous system development GO:0007417 123 0.036
organelle assembly GO:0070925 176 0.035
neurogenesis GO:0022008 169 0.034
nuclear transport GO:0051169 179 0.033
negative regulation of programmed cell death GO:0043069 321 0.032
response to organic cyclic compound GO:0014070 204 0.032
positive regulation of cell proliferation GO:0008284 301 0.032
regulation of protein import into nucleus GO:0042306 78 0.031
mitotic nuclear division GO:0007067 119 0.030
rna 3 end processing GO:0031123 35 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
osteoblast differentiation GO:0001649 92 0.029
cytoplasmic transport GO:0016482 379 0.029
positive regulation of growth GO:0045927 58 0.029
apoptotic signaling pathway GO:0097190 268 0.029
single organism nuclear import GO:1902593 104 0.029
protein catabolic process GO:0030163 325 0.028
cell morphogenesis GO:0000902 296 0.027
sex differentiation GO:0007548 45 0.026
regulation of apoptotic signaling pathway GO:2001233 175 0.025
establishment of nucleus localization GO:0040023 1 0.025
response to virus GO:0009615 126 0.025
regulation of proteasomal protein catabolic process GO:0061136 87 0.024
negative regulation of cell death GO:0060548 345 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
positive regulation of response to dna damage stimulus GO:2001022 43 0.024
regulation of cell differentiation GO:0045595 393 0.023
protein processing GO:0016485 226 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
spindle elongation GO:0051231 4 0.023
anterior posterior axis specification embryo GO:0008595 2 0.023
positive regulation of intracellular transport GO:0032388 104 0.022
intracellular protein transport GO:0006886 270 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
regulation of proteolysis GO:0030162 293 0.022
segmentation GO:0035282 4 0.021
positive regulation of protein import into nucleus GO:0042307 46 0.020
protein localization to nucleus GO:0034504 136 0.020
protein maturation GO:0051604 233 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
action potential GO:0001508 34 0.020
meiotic chromosome segregation GO:0045132 4 0.019
cellular response to cytokine stimulus GO:0071345 181 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.019
positive regulation of developmental growth GO:0048639 16 0.018
positive regulation of cell death GO:0010942 263 0.018
purine containing compound catabolic process GO:0072523 411 0.018
negative regulation of protein processing GO:0010955 142 0.018
regulation of locomotion GO:0040012 329 0.018
regulation of mitotic cell cycle GO:0007346 189 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
trna metabolic process GO:0006399 35 0.018
nuclear import GO:0051170 106 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
gamete generation GO:0007276 25 0.017
maturation of lsu rrna GO:0000470 3 0.016
protein localization to organelle GO:0033365 280 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
response to external biotic stimulus GO:0043207 261 0.016
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.016
cellular protein complex assembly GO:0043623 188 0.016
cytokine production GO:0001816 247 0.015
single organism reproductive process GO:0044702 98 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
regulation of dephosphorylation GO:0035303 96 0.015
response to nitrogen compound GO:1901698 184 0.015
response to cytokine GO:0034097 232 0.015
regulation of transferase activity GO:0051338 355 0.015
response to abiotic stimulus GO:0009628 336 0.015
multi organism reproductive process GO:0044703 54 0.015
positive regulation of protein transport GO:0051222 135 0.015
regulation of protein kinase activity GO:0045859 289 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
cellular response to nitrogen compound GO:1901699 144 0.014
regulation of gene expression epigenetic GO:0040029 73 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
genitalia development GO:0048806 10 0.014
system process GO:0003008 349 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
neuron development GO:0048666 113 0.014
response to other organism GO:0051707 261 0.014
positive regulation of hydrolase activity GO:0051345 331 0.013
sexual reproduction GO:0019953 37 0.013
nucleoside catabolic process GO:0009164 408 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
regulation of response to external stimulus GO:0032101 222 0.013
neuron differentiation GO:0030182 138 0.012
regulation of cell cycle GO:0051726 393 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
dna repair GO:0006281 198 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
oocyte development GO:0048599 1 0.012
transmission of nerve impulse GO:0019226 11 0.011
mitotic cell cycle process GO:1903047 286 0.011
male sex differentiation GO:0046661 25 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
response to biotic stimulus GO:0009607 276 0.011
regulation of protein catabolic process GO:0042176 155 0.011
immune response GO:0006955 307 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
dephosphorylation GO:0016311 209 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
mrna processing GO:0006397 133 0.011
hemopoiesis GO:0030097 180 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
cell growth GO:0016049 160 0.011
mitotic cell cycle GO:0000278 326 0.010
cell cell signaling GO:0007267 155 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
positive regulation of transferase activity GO:0051347 227 0.010
cell part morphogenesis GO:0032990 137 0.010
mrna catabolic process GO:0006402 56 0.010
purine nucleotide biosynthetic process GO:0006164 84 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
negative regulation of catalytic activity GO:0043086 335 0.010
regulation of developmental growth GO:0048638 30 0.010
single fertilization GO:0007338 11 0.010

EIF2S1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012