Homo sapiens

18 known processes

EIF2S3

eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa

(Aliases: EIF2G,EIF2gamma,EIF2,eIF-2gA)

EIF2S3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.332
Worm
rab protein signal transduction GO:0032482 4 0.305
translation GO:0006412 132 0.219
determination of adult lifespan GO:0008340 2 0.215
positive regulation of rab gtpase activity GO:0032851 39 0.147
multicellular organismal aging GO:0010259 3 0.143
segmentation GO:0035282 4 0.085
cellular amino acid metabolic process GO:0006520 116 0.076
protein localization to membrane GO:0072657 160 0.070
anterior posterior axis specification GO:0009948 2 0.069
regulation of rab protein signal transduction GO:0032483 39 0.067
female gamete generation GO:0007292 2 0.063
guanosine containing compound metabolic process GO:1901068 244 0.062
small molecule biosynthetic process GO:0044283 157 0.059
transmembrane transport GO:0055085 399 0.057
negative regulation of cell death GO:0060548 345 0.057
system process GO:0003008 349 0.055
purine ribonucleoside catabolic process GO:0046130 398 0.053
protein targeting GO:0006605 187 0.052
organophosphate catabolic process GO:0046434 430 0.052
ribonucleoprotein complex assembly GO:0022618 78 0.051
Yeast
nervous system development GO:0007399 293 0.049
vesicle mediated transport GO:0016192 371 0.049
purine ribonucleoside metabolic process GO:0046128 437 0.048
glycosyl compound catabolic process GO:1901658 413 0.048
nucleoside triphosphate catabolic process GO:0009143 394 0.048
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.047
mitochondrion organization GO:0007005 156 0.047
organonitrogen compound biosynthetic process GO:1901566 200 0.046
single organism cellular localization GO:1902580 332 0.045
purine nucleoside catabolic process GO:0006152 398 0.044
oogenesis GO:0048477 2 0.043
locomotory behavior GO:0007626 1 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
ras protein signal transduction GO:0007265 73 0.040
positive regulation of programmed cell death GO:0043068 249 0.039
single organism membrane organization GO:0044802 268 0.038
purine containing compound catabolic process GO:0072523 411 0.038
endocytosis GO:0006897 159 0.038
ribonucleotide catabolic process GO:0009261 405 0.038
establishment of protein localization to membrane GO:0090150 121 0.038
small gtpase mediated signal transduction GO:0007264 78 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.037
neuromuscular junction development GO:0007528 3 0.037
purine ribonucleotide catabolic process GO:0009154 404 0.037
regulation of protein localization GO:0032880 296 0.036
neurotransmitter secretion GO:0007269 4 0.036
positive regulation of cell death GO:0010942 263 0.036
negative regulation of catalytic activity GO:0043086 335 0.036
positive regulation of ras gtpase activity GO:0032320 117 0.036
ribonucleoside triphosphate catabolic process GO:0009203 391 0.036
nucleoside catabolic process GO:0009164 408 0.035
regeneration GO:0031099 4 0.035
negative regulation of apoptotic process GO:0043066 316 0.035
response to abiotic stimulus GO:0009628 336 0.034
ribonucleoside triphosphate metabolic process GO:0009199 412 0.034
positive regulation of cell proliferation GO:0008284 301 0.034
regulation of gtp catabolic process GO:0033124 180 0.034
nucleoside triphosphate metabolic process GO:0009141 422 0.033
positive regulation of gtp catabolic process GO:0033126 166 0.033
regulation of purine nucleotide metabolic process GO:1900542 264 0.032
lipid metabolic process GO:0006629 381 0.032
regulation of growth GO:0040008 165 0.032
Worm
intracellular protein transport GO:0006886 270 0.032
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
positive regulation of transport GO:0051050 336 0.031
guanosine containing compound catabolic process GO:1901069 239 0.031
sensory perception GO:0007600 103 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
endomembrane system organization GO:0010256 196 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.030
somitogenesis GO:0001756 2 0.030
monocarboxylic acid metabolic process GO:0032787 185 0.029
cytoplasmic transport GO:0016482 379 0.029
carboxylic acid biosynthetic process GO:0046394 97 0.029
secretion GO:0046903 254 0.029
membrane organization GO:0061024 292 0.029
organelle assembly GO:0070925 176 0.029
organic acid biosynthetic process GO:0016053 97 0.029
regulation of nucleoside metabolic process GO:0009118 209 0.028
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.028
nucleotide catabolic process GO:0009166 408 0.028
oxidation reduction process GO:0055114 396 0.027
regulation of nucleotide catabolic process GO:0030811 205 0.027
response to external biotic stimulus GO:0043207 261 0.027
circulatory system development GO:0072359 262 0.027
purine nucleotide catabolic process GO:0006195 405 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
ribonucleoprotein complex subunit organization GO:0071826 81 0.027
Yeast
regulation of cell cycle process GO:0010564 266 0.027
growth GO:0040007 202 0.027
Worm
gtp catabolic process GO:0006184 237 0.026
regulation of cell differentiation GO:0045595 393 0.026
regulation of translation GO:0006417 89 0.026
Yeast
regulation of apoptotic signaling pathway GO:2001233 175 0.026
positive regulation of developmental process GO:0051094 314 0.026
Worm
regulation of gtpase activity GO:0043087 180 0.025
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
cardiovascular system development GO:0072358 262 0.025
gtp metabolic process GO:0046039 239 0.025
embryo development GO:0009790 123 0.025
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.025
positive regulation of apoptotic process GO:0043065 246 0.025
apoptotic signaling pathway GO:0097190 268 0.025
ribonucleoprotein complex biogenesis GO:0022613 116 0.025
Yeast
rhythmic behavior GO:0007622 2 0.025
positive regulation of catabolic process GO:0009896 310 0.025
cellular homeostasis GO:0019725 196 0.025
negative regulation of transport GO:0051051 176 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.024
Yeast
negative regulation of cellular component organization GO:0051129 235 0.024
protein localization to organelle GO:0033365 280 0.024
regulation of cell cycle GO:0051726 393 0.024
mrna processing GO:0006397 133 0.024
secretion by cell GO:0032940 226 0.024
spermatid differentiation GO:0048515 4 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
cellular lipid metabolic process GO:0044255 303 0.023
cellular amino acid biosynthetic process GO:0008652 30 0.023
cofactor metabolic process GO:0051186 87 0.023
cellular modified amino acid biosynthetic process GO:0042398 15 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
regulation of cellular response to stress GO:0080135 244 0.023
cell cell signaling GO:0007267 155 0.023
regulation of intracellular transport GO:0032386 195 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
response to cytokine GO:0034097 232 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
cellular response to nitrogen compound GO:1901699 144 0.022
viral process GO:0016032 146 0.022
amine metabolic process GO:0009308 44 0.022
chromatin organization GO:0006325 351 0.022
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.022
nuclear transport GO:0051169 179 0.021
neurological system process GO:0050877 163 0.021
cellular cation homeostasis GO:0030003 163 0.021
leukocyte activation GO:0045321 164 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
protein oligomerization GO:0051259 173 0.021
regulation of cell growth GO:0001558 135 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
wound healing GO:0042060 115 0.020
negative regulation of cellular response to oxidative stress GO:1900408 18 0.020
spermatid development GO:0007286 4 0.020
interspecies interaction between organisms GO:0044419 156 0.020
cation homeostasis GO:0055080 189 0.020
cellular amine metabolic process GO:0044106 41 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
regulation of protein transport GO:0051223 213 0.020
response to oxygen containing compound GO:1901700 369 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.019
cell development GO:0048468 328 0.019
prenylation GO:0097354 6 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
multi organism cellular process GO:0044764 156 0.019
oocyte development GO:0048599 1 0.019
cell morphogenesis GO:0000902 296 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
cell activation GO:0001775 213 0.019
memory GO:0007613 3 0.019
cell type specific apoptotic process GO:0097285 125 0.019
lung alveolus development GO:0048286 4 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
ion homeostasis GO:0050801 230 0.019
regulation of neural precursor cell proliferation GO:2000177 4 0.019
carbohydrate metabolic process GO:0005975 207 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
cellular ketone metabolic process GO:0042180 80 0.018
protein localization to plasma membrane GO:0072659 93 0.018
mrna metabolic process GO:0016071 175 0.018
response to fungus GO:0009620 4 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
neural tube formation GO:0001841 3 0.018
response to nitrogen compound GO:1901698 184 0.018
regulation of ras gtpase activity GO:0032318 128 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
rna splicing via transesterification reactions GO:0000375 90 0.018
wnt signaling pathway GO:0016055 156 0.017
metal ion transport GO:0030001 272 0.017
photoreceptor cell differentiation GO:0046530 2 0.017
positive regulation of growth GO:0045927 58 0.017
Worm
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
oocyte differentiation GO:0009994 2 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
cellular component morphogenesis GO:0032989 314 0.017
aging GO:0007568 66 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.017
protein catabolic process GO:0030163 325 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
regulation of intracellular protein transport GO:0033157 123 0.017
lipid biosynthetic process GO:0008610 177 0.017
positive regulation of gtpase activity GO:0043547 166 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
cofactor biosynthetic process GO:0051188 31 0.017
tripartite regional subdivision GO:0007351 2 0.017
engulfment of apoptotic cell GO:0043652 2 0.017
compound eye development GO:0048749 1 0.017
organophosphate biosynthetic process GO:0090407 163 0.016
regulation of multi organism process GO:0043900 157 0.016
rna interference GO:0016246 4 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
Yeast
motor neuron axon guidance GO:0008045 2 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
regulation of response to oxidative stress GO:1902882 26 0.016
cellular modified amino acid metabolic process GO:0006575 64 0.015
viral life cycle GO:0019058 132 0.015
tissue regeneration GO:0042246 3 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
blastoderm segmentation GO:0007350 2 0.015
response to other organism GO:0051707 261 0.015
rna splicing GO:0008380 131 0.015
regulation of protein targeting GO:1903533 91 0.015
cell growth GO:0016049 160 0.015
regulation of cell migration GO:0030334 289 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
defense response GO:0006952 315 0.015
response to wounding GO:0009611 168 0.015
negative regulation of catabolic process GO:0009895 104 0.015
sensory perception of pain GO:0019233 4 0.015
regulation of cellular component movement GO:0051270 334 0.015
mating GO:0007618 1 0.015
demethylation GO:0070988 37 0.015
plasma membrane organization GO:0007009 115 0.015
actin filament based process GO:0030029 224 0.015
circadian behavior GO:0048512 2 0.015
regulation of neuron projection development GO:0010975 57 0.015
purine containing compound biosynthetic process GO:0072522 88 0.015
negative regulation of multi organism process GO:0043901 92 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
cellular response to dna damage stimulus GO:0006974 379 0.014
neuron projection development GO:0031175 106 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
regulation of ion transport GO:0043269 189 0.014
nitrogen compound transport GO:0071705 191 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
protein maturation GO:0051604 233 0.014
divalent inorganic cation transport GO:0072511 158 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
chemical homeostasis GO:0048878 306 0.014
negative regulation of viral process GO:0048525 66 0.014
cation transport GO:0006812 331 0.014
purine nucleotide biosynthetic process GO:0006164 84 0.014
regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000622 3 0.014
establishment of protein localization to mitochondrion GO:0072655 22 0.014
regulation of epithelial cell proliferation GO:0050678 113 0.013
cellular response to abiotic stimulus GO:0071214 117 0.013
cell death in response to oxidative stress GO:0036473 29 0.013
mrna splicing via spliceosome GO:0000398 89 0.013
protein processing GO:0016485 226 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
protein secretion GO:0009306 98 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
trabecula morphogenesis GO:0061383 2 0.013
cation transmembrane transport GO:0098655 238 0.013
associative learning GO:0008306 1 0.013
regulation of oxidative stress induced cell death GO:1903201 24 0.013
actin mediated cell contraction GO:0070252 12 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
cilium morphogenesis GO:0060271 75 0.013
divalent metal ion transport GO:0070838 152 0.013
regulation of cell development GO:0060284 161 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
sulfur compound metabolic process GO:0006790 101 0.013
pigment biosynthetic process GO:0046148 10 0.013
regulation of secretion GO:0051046 194 0.013
cellular protein catabolic process GO:0044257 261 0.013
histone modification GO:0016570 251 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.013
cell cycle g1 s phase transition GO:0044843 80 0.013
response to organonitrogen compound GO:0010243 156 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
cellular amide metabolic process GO:0043603 69 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
epithelium development GO:0060429 227 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
positive regulation of dendrite morphogenesis GO:0050775 3 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
mitotic cell cycle process GO:1903047 286 0.012
cellular response to oxidative stress GO:0034599 85 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
lymphocyte homeostasis GO:0002260 4 0.012
response to hormone GO:0009725 175 0.012
tube closure GO:0060606 3 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
cell fate determination GO:0001709 3 0.012
regulation of locomotion GO:0040012 329 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
response to inorganic substance GO:0010035 127 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
cell division GO:0051301 168 0.012
golgi vesicle transport GO:0048193 80 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
cell part morphogenesis GO:0032990 137 0.011
regulation of proteolysis GO:0030162 293 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
hemopoiesis GO:0030097 180 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
response to biotic stimulus GO:0009607 276 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
cell cycle phase transition GO:0044770 173 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
coenzyme metabolic process GO:0006732 65 0.011
positive regulation of immune system process GO:0002684 283 0.011
central nervous system development GO:0007417 123 0.011
regulation of camp metabolic process GO:0030814 52 0.011
reproductive structure development GO:0048608 55 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
cell projection organization GO:0030030 252 0.011
chromatin modification GO:0016568 298 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
protein homooligomerization GO:0051260 100 0.011
immune system development GO:0002520 195 0.011
response to axon injury GO:0048678 1 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.011
regulation of nervous system development GO:0051960 88 0.011
neural tube closure GO:0001843 3 0.011
metal ion homeostasis GO:0055065 169 0.011
neuroblast proliferation GO:0007405 4 0.011
anion transport GO:0006820 161 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
lymphocyte activation GO:0046649 133 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
t cell homeostasis GO:0043029 3 0.011
regulation of cell projection organization GO:0031344 107 0.011
maintenance of location GO:0051235 112 0.011
reproduction GO:0000003 63 0.011
Worm
receptor mediated endocytosis GO:0006898 84 0.011
negative regulation of growth GO:0045926 97 0.011
positive regulation of cell cycle GO:0045787 140 0.011
inorganic ion transmembrane transport GO:0098660 231 0.010
positive regulation of cell growth GO:0030307 48 0.010
lung saccule development GO:0060430 2 0.010
macromolecule methylation GO:0043414 97 0.010
positive regulation of meiotic cell cycle GO:0051446 2 0.010
axis elongation GO:0003401 4 0.010
meiotic chromosome segregation GO:0045132 4 0.010
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
ion transmembrane transport GO:0034220 338 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
regulation of viral process GO:0050792 103 0.010
negative regulation of axon extension GO:0030517 2 0.010
macromolecule glycosylation GO:0043413 63 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
autophagic cell death GO:0048102 3 0.010
endothelial cell proliferation GO:0001935 65 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
response to virus GO:0009615 126 0.010
regulation of protein kinase activity GO:0045859 289 0.010
cardiac muscle contraction GO:0060048 34 0.010
head development GO:0060322 108 0.010
convergent extension GO:0060026 1 0.010

EIF2S3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
musculoskeletal system disease DOID:17 223 0.017
sensory system disease DOID:0050155 203 0.014
neurodegenerative disease DOID:1289 102 0.014
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
auditory system disease DOID:2742 53 0.011
disease of metabolism DOID:0014667 295 0.011
neuropathy DOID:870 52 0.011
disease of cellular proliferation DOID:14566 174 0.011
disease of mental health DOID:150 70 0.010