|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.918
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.823
|
|
|
|
hippo signaling
|
GO:0035329 |
20 |
0.741
|
|
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.736
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.725
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.712
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.690
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.672
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.646
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.628
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.620
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.595
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.584
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.570
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.555
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.535
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.530
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.523
|
Zebrafish Fly |
|
|
cellular response to gonadotropin stimulus
|
GO:0071371 |
4 |
0.499
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.494
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.479
|
Human |
|
|
positive regulation of glomerular mesangial cell proliferation
|
GO:0072126 |
1 |
0.477
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.469
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.460
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.459
|
|
|
|
s shaped body morphogenesis
|
GO:0072050 |
4 |
0.422
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.404
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.400
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.388
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.376
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.373
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.364
|
Human |
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.363
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.360
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.357
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.345
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.335
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.332
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.327
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.323
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.322
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.316
|
Human |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.315
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.304
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.302
|
Human Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.293
|
Human |
|
|
metanephric s shaped body morphogenesis
|
GO:0072284 |
4 |
0.291
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.287
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.286
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.281
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.272
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.272
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.269
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.269
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.269
|
Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.269
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.262
|
Mouse Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.255
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.246
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.241
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.239
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.239
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.236
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.229
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.229
|
|
|
|
positive regulation of metanephros development
|
GO:0072216 |
3 |
0.227
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.225
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.224
|
Human |
|
|
metanephric nephron morphogenesis
|
GO:0072273 |
7 |
0.223
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.222
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.222
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.221
|
Human |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.218
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.218
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.217
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.215
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.213
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.211
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.211
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.207
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.205
|
|
|
|
growth
|
GO:0040007 |
202 |
0.204
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.202
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.202
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.201
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.200
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.196
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.196
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.193
|
Human Zebrafish |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.189
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.186
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.186
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.184
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.184
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.184
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.184
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.180
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.179
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.179
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.178
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.177
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.176
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.176
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.173
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.173
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.172
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.172
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.171
|
|
|
|
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0016339 |
2 |
0.171
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.170
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.169
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.168
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.162
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.161
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.159
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.159
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.158
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.158
|
Human Mouse |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.157
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.157
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.157
|
|
|
|
negative regulation of hippo signaling
|
GO:0035331 |
6 |
0.157
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.156
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.153
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.153
|
Fly |
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.152
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.151
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.150
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.148
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.148
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.147
|
Human |
|
|
metanephric epithelium development
|
GO:0072207 |
7 |
0.147
|
|
|
|
excretion
|
GO:0007588 |
9 |
0.146
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.145
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.145
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.145
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.139
|
Human Mouse Fly |
|
|
digestive system development
|
GO:0055123 |
75 |
0.138
|
Zebrafish Mouse Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.138
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.138
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.137
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.137
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.137
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.135
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.135
|
Fly |
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.135
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.132
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.132
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.131
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.131
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.130
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.128
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.128
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.127
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.127
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.127
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.126
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.126
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.126
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.125
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.125
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.125
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.121
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.120
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.119
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.119
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.119
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.117
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.117
|
Human |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.115
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.115
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.114
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.113
|
Mouse Fly |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.113
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.113
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.113
|
Human |
|
|
glomerular basement membrane development
|
GO:0032836 |
3 |
0.112
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.112
|
|
|
|
protein localization to cytoskeleton
|
GO:0044380 |
11 |
0.112
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.112
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.111
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.110
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.109
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.109
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.109
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.108
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.107
|
Zebrafish Mouse Fly |
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.106
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.105
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.103
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.102
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.102
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.102
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.101
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.101
|
Zebrafish Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.101
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.101
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.101
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.100
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.100
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.099
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.099
|
Human Mouse Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.098
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.097
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.096
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.095
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.095
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.094
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.093
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.093
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.091
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.091
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.091
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.091
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.091
|
|
|
|
male gonad development
|
GO:0008584 |
23 |
0.090
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.090
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.090
|
Human |
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.089
|
|
|
|
glomerular mesangial cell proliferation
|
GO:0072110 |
3 |
0.089
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.089
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.088
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.088
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.088
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.088
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.088
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.088
|
Human Mouse |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.088
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.088
|
Zebrafish Mouse Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.087
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.087
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.087
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.086
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.086
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.086
|
Fly |
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.086
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.086
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.085
|
Zebrafish Mouse Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.085
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.085
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.084
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.084
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.083
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.083
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.083
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.082
|
Fly |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.082
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.082
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.082
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.081
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.080
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.080
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.080
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.080
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.080
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.080
|
Human |
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.079
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.079
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.078
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.078
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.077
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.077
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.077
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.077
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.076
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.076
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.076
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.075
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.075
|
Fly |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.074
|
Fly |
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.073
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.073
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.073
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.072
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.072
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.072
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.072
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.072
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.072
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.071
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.071
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.071
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.071
|
Fly |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.070
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.069
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.068
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.068
|
Human |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.068
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.067
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.067
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.066
|
Zebrafish Mouse Fly |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.066
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.066
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.065
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.065
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.065
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.065
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.065
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.064
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.064
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.064
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.064
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.064
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.064
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.063
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.063
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.063
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.063
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.063
|
Human |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.063
|
Fly |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.062
|
Human Zebrafish |
|
|
regeneration
|
GO:0031099 |
4 |
0.061
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.061
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.061
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.061
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.061
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.061
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.060
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.060
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.060
|
Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.060
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.059
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.059
|
Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.059
|
Human |
|
|
gliogenesis
|
GO:0042063 |
21 |
0.059
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.058
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.058
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.058
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.057
|
Human |
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.057
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.056
|
|
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.055
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.055
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.055
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.055
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.054
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.054
|
Mouse Fly |
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.054
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.054
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.054
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.054
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.054
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.054
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.053
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.053
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.053
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.053
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.053
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.052
|
Fly |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.052
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.051
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.051
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.051
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.051
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.050
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.050
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.050
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.050
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.049
|
|
|
|
kidney vasculature development
|
GO:0061440 |
7 |
0.049
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.049
|
Zebrafish Mouse Fly |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.049
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.049
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.048
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.048
|
Mouse |
|
|
cellular response to antibiotic
|
GO:0071236 |
1 |
0.048
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.048
|
|
|
|
follicle stimulating hormone secretion
|
GO:0046884 |
3 |
0.048
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.047
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.047
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.047
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.046
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.046
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.046
|
Human Zebrafish |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.046
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.046
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.046
|
|
|
|
response to hexose
|
GO:0009746 |
20 |
0.046
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.045
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.045
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.045
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.045
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.045
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.045
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.044
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.044
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.044
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.044
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.044
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.043
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.043
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.043
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.043
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.043
|
|
|
|
cellular response to vascular endothelial growth factor stimulus
|
GO:0035924 |
26 |
0.043
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.042
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.042
|
|
|
|
metanephric nephron development
|
GO:0072210 |
9 |
0.042
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.042
|
Fly |
|
|
cellular response to heparin
|
GO:0071504 |
2 |
0.042
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.042
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.042
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.042
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.041
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.041
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.041
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.041
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.041
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.041
|
Fly |
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.041
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.041
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.041
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.040
|
Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.040
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.040
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.040
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.040
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.040
|
Fly |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.040
|
|
|
|
cellular response to alkaloid
|
GO:0071312 |
11 |
0.040
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.039
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.039
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.039
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.039
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.039
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.039
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.039
|
Fly |
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.039
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.039
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.039
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
10 |
0.038
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.038
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.038
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.038
|
Human Zebrafish |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.038
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.038
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.038
|
Fly |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.037
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.037
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.037
|
Fly |
|
|
hair cycle
|
GO:0042633 |
28 |
0.037
|
Mouse |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.037
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.037
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.037
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.037
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.037
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.037
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.037
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.037
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.037
|
|
|
|
positive regulation of cell proliferation involved in kidney development
|
GO:1901724 |
1 |
0.037
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.037
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.037
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.036
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.036
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.036
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.036
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.036
|
Human |
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.036
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.036
|
|
|
|
response to heparin
|
GO:0071503 |
3 |
0.036
|
|
|
|
head development
|
GO:0060322 |
108 |
0.036
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
15 |
0.036
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.035
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.035
|
Human |
|
|
response to electrical stimulus
|
GO:0051602 |
1 |
0.035
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.034
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.034
|
Fly |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.034
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.034
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.034
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.034
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.034
|
|
|
|
metanephric glomerulus development
|
GO:0072224 |
2 |
0.034
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.034
|
Mouse |
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.033
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.033
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.033
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.033
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.033
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.033
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.033
|
Human Zebrafish |
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.032
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.032
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.032
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.032
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.032
|
Human |
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.032
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.032
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.032
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.032
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.032
|
|
|
|
demethylation
|
GO:0070988 |
37 |
0.032
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.032
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.032
|
Mouse |
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.032
|
|
