Homo sapiens

32 known processes

PTTG1IP

pituitary tumor-transforming 1 interacting protein

(Aliases: PBF,C21orf3,C21orf1)

PTTG1IP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 371 0.074
regulation of protein localization GO:0032880 296 0.070
small gtpase mediated signal transduction GO:0007264 78 0.065
glycosyl compound catabolic process GO:1901658 413 0.062
purine nucleoside catabolic process GO:0006152 398 0.061
post embryonic development GO:0009791 2 0.059
protein catabolic process GO:0030163 325 0.057
negative regulation of cellular protein metabolic process GO:0032269 353 0.055
ras protein signal transduction GO:0007265 73 0.054
purine ribonucleotide catabolic process GO:0009154 404 0.053
positive regulation of cellular catabolic process GO:0031331 284 0.053
ribonucleoside catabolic process GO:0042454 406 0.051
cytoplasmic transport GO:0016482 379 0.051
cell adhesion GO:0007155 325 0.050
protein processing GO:0016485 226 0.049
regulation of protein maturation GO:1903317 150 0.049
cell development GO:0048468 328 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.048
negative regulation of locomotion GO:0040013 118 0.047
enzyme linked receptor protein signaling pathway GO:0007167 303 0.047
nucleoside triphosphate catabolic process GO:0009143 394 0.047
ribonucleotide catabolic process GO:0009261 405 0.046
positive regulation of transport GO:0051050 336 0.045
negative regulation of protein metabolic process GO:0051248 391 0.044
positive regulation of catabolic process GO:0009896 310 0.044
regulation of rubidium ion transport GO:2000680 3 0.044
carbohydrate derivative biosynthetic process GO:1901137 207 0.043
biological adhesion GO:0022610 331 0.043
apoptotic signaling pathway GO:0097190 268 0.042
rho protein signal transduction GO:0007266 26 0.042
purine containing compound catabolic process GO:0072523 411 0.042
ribonucleoside triphosphate metabolic process GO:0009199 412 0.041
positive regulation of programmed cell death GO:0043068 249 0.041
nucleoside catabolic process GO:0009164 408 0.041
organophosphate catabolic process GO:0046434 430 0.041
purine nucleoside triphosphate catabolic process GO:0009146 392 0.040
carbohydrate metabolic process GO:0005975 207 0.040
endomembrane system organization GO:0010256 196 0.040
purine nucleotide catabolic process GO:0006195 405 0.040
protein maturation GO:0051604 233 0.039
regulation of locomotion GO:0040012 329 0.038
glycoprotein metabolic process GO:0009100 110 0.038
nucleoside triphosphate metabolic process GO:0009141 422 0.037
purine ribonucleoside catabolic process GO:0046130 398 0.037
oogenesis GO:0048477 2 0.037
amine metabolic process GO:0009308 44 0.037
positive regulation of hydrolase activity GO:0051345 331 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.037
purine nucleoside triphosphate metabolic process GO:0009144 412 0.036
regulation of peptidase activity GO:0052547 180 0.036
cellular amino acid metabolic process GO:0006520 116 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
gtp catabolic process GO:0006184 237 0.035
regulation of cellular component movement GO:0051270 334 0.035
ribonucleoside triphosphate catabolic process GO:0009203 391 0.034
multicellular organismal aging GO:0010259 3 0.034
gtp metabolic process GO:0046039 239 0.034
negative regulation of protein maturation GO:1903318 142 0.034
secretion GO:0046903 254 0.034
segmentation GO:0035282 4 0.034
epithelium development GO:0060429 227 0.033
negative regulation of catalytic activity GO:0043086 335 0.033
single organism membrane organization GO:0044802 268 0.033
regulation of multi organism process GO:0043900 157 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.032
response to growth factor GO:0070848 205 0.032
nucleotide catabolic process GO:0009166 408 0.032
regulation of purine nucleotide metabolic process GO:1900542 264 0.032
positive regulation of cellular component organization GO:0051130 376 0.031
positive regulation of cell death GO:0010942 263 0.031
regulation of cell motility GO:2000145 299 0.031
secretion by cell GO:0032940 226 0.030
actin filament based process GO:0030029 224 0.030
neuroblast proliferation GO:0007405 4 0.030
negative regulation of multicellular organismal process GO:0051241 317 0.030
cellular component morphogenesis GO:0032989 314 0.030
regulation of vesicle mediated transport GO:0060627 130 0.030
regulation of secretion GO:0051046 194 0.029
negative regulation of protein processing GO:0010955 142 0.029
negative regulation of cell migration GO:0030336 102 0.029
regulation of protein processing GO:0070613 150 0.029
negative regulation of programmed cell death GO:0043069 321 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.029
glycoprotein biosynthetic process GO:0009101 91 0.029
regulation of cell differentiation GO:0045595 393 0.028
transmembrane transport GO:0055085 399 0.028
negative regulation of cellular component movement GO:0051271 106 0.028
membrane organization GO:0061024 292 0.027
cell activation GO:0001775 213 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.027
female gamete generation GO:0007292 2 0.026
guanosine containing compound catabolic process GO:1901069 239 0.026
regulation of ion transport GO:0043269 189 0.026
chemical homeostasis GO:0048878 306 0.026
positive regulation of gtpase activity GO:0043547 166 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
cellular ketone metabolic process GO:0042180 80 0.025
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
locomotory behavior GO:0007626 1 0.024
regulation of cell migration GO:0030334 289 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
regulation of endopeptidase activity GO:0052548 170 0.024
cellular response to endogenous stimulus GO:0071495 336 0.024
mating GO:0007618 1 0.024
ion transmembrane transport GO:0034220 338 0.024
mitotic cell cycle GO:0000278 326 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.023
protein oligomerization GO:0051259 173 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
cellular amine metabolic process GO:0044106 41 0.023
response to wounding GO:0009611 168 0.023
regulation of exocytosis GO:0017157 46 0.023
cellular cation homeostasis GO:0030003 163 0.023
cell morphogenesis GO:0000902 296 0.023
protein localization to organelle GO:0033365 280 0.023
endosomal transport GO:0016197 129 0.023
ion homeostasis GO:0050801 230 0.022
vasculature development GO:0001944 181 0.022
response to abiotic stimulus GO:0009628 336 0.022
cellular chemical homeostasis GO:0055082 180 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
positive regulation of synaptic transmission GO:0050806 4 0.022
cellular homeostasis GO:0019725 196 0.022
establishment of protein localization to membrane GO:0090150 121 0.022
regulation of protein catabolic process GO:0042176 155 0.022
cation transport GO:0006812 331 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
intracellular protein transport GO:0006886 270 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
response to oxygen containing compound GO:1901700 369 0.021
positive regulation of immune system process GO:0002684 283 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
regulation of protein localization to cell surface GO:2000008 15 0.021
negative regulation of cell motility GO:2000146 104 0.021
regulation of cell cycle GO:0051726 393 0.021
anterior posterior axis specification GO:0009948 2 0.021
negative regulation of cell death GO:0060548 345 0.021
wnt signaling pathway GO:0016055 156 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
positive regulation of developmental process GO:0051094 314 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
peripheral nervous system development GO:0007422 2 0.020
immune response GO:0006955 307 0.020
regulation of secretion by cell GO:1903530 177 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
regulation of nucleoside metabolic process GO:0009118 209 0.020
protein localization to membrane GO:0072657 160 0.020
negative regulation of trophoblast cell migration GO:1901164 3 0.019
chloride transmembrane transport GO:1902476 38 0.019
regulation of proteolysis GO:0030162 293 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
regulation of transferase activity GO:0051338 355 0.019
actin cytoskeleton organization GO:0030036 207 0.019
cardiovascular system development GO:0072358 262 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
system process GO:0003008 349 0.019
regulation of gtp catabolic process GO:0033124 180 0.019
spermatid differentiation GO:0048515 4 0.019
regulation of immune response GO:0050776 201 0.019
protein modification by small protein conjugation GO:0032446 342 0.018
wound healing GO:0042060 115 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
regulation of cellular response to growth factor stimulus GO:0090287 76 0.018
positive regulation of gtp catabolic process GO:0033126 166 0.018
cell substrate adhesion GO:0031589 132 0.018
regulation of neural precursor cell proliferation GO:2000177 4 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
rubidium ion transport GO:0035826 4 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
anion transport GO:0006820 161 0.018
determination of adult lifespan GO:0008340 2 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
negative regulation of proteolysis GO:0045861 132 0.018
neurotransmitter secretion GO:0007269 4 0.018
exocytosis GO:0006887 71 0.018
protein ubiquitination GO:0016567 314 0.018
regulation of metalloenzyme activity GO:0048552 3 0.018
negative regulation of developmental process GO:0051093 247 0.017
rab protein signal transduction GO:0032482 4 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
positive regulation of exocytosis GO:0045921 35 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
ameboidal type cell migration GO:0001667 135 0.017
cell cycle phase transition GO:0044770 173 0.017
cation homeostasis GO:0055080 189 0.017
regulation of defense response GO:0031347 154 0.017
blastoderm segmentation GO:0007350 2 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
single organism cellular localization GO:1902580 332 0.017
hemopoiesis GO:0030097 180 0.017
Zebrafish
establishment of protein localization to plasma membrane GO:0090002 68 0.017
autophagy GO:0006914 88 0.017
regulation of neuroblast proliferation GO:1902692 3 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
plasma membrane organization GO:0007009 115 0.016
regulation of protein kinase activity GO:0045859 289 0.016
response to biotic stimulus GO:0009607 276 0.016
organelle assembly GO:0070925 176 0.016
neurogenesis GO:0022008 169 0.016
microtubule based process GO:0007017 210 0.016
angiogenesis GO:0001525 147 0.016
cell growth GO:0016049 160 0.016
protein homooligomerization GO:0051260 100 0.016
protein glycosylation GO:0006486 62 0.016
positive regulation of ras gtpase activity GO:0032320 117 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
atp metabolic process GO:0046034 176 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
blood vessel morphogenesis GO:0048514 162 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
positive regulation of secretion GO:0051047 116 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
organ formation GO:0048645 3 0.016
regulation of integrin mediated signaling pathway GO:2001044 3 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
mitotic cell cycle process GO:1903047 286 0.016
negative regulation of cell cycle GO:0045786 193 0.015
generation of neurons GO:0048699 152 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
cellular protein catabolic process GO:0044257 261 0.015
atp catabolic process GO:0006200 157 0.015
regeneration GO:0031099 4 0.015
regulation of response to external stimulus GO:0032101 222 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
circulatory system development GO:0072359 262 0.015
regulation of protein transport GO:0051223 213 0.015
cell division GO:0051301 168 0.015
metal ion homeostasis GO:0055065 169 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
i kappab kinase nf kappab signaling GO:0007249 166 0.015
single organism cell adhesion GO:0098602 179 0.015
adult locomotory behavior GO:0008344 1 0.015
response to other organism GO:0051707 261 0.015
monovalent inorganic cation transport GO:0015672 128 0.015
negative regulation of protein modification process GO:0031400 200 0.015
negative regulation of catabolic process GO:0009895 104 0.015
response to hormone GO:0009725 175 0.015
oocyte differentiation GO:0009994 2 0.015
cellular response to glucocorticoid stimulus GO:0071385 4 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
cytokine production GO:0001816 247 0.015
positive regulation of transferase activity GO:0051347 227 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
cell projection organization GO:0030030 252 0.015
innate immune response GO:0045087 178 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
positive regulation of organelle organization GO:0010638 195 0.014
tripartite regional subdivision GO:0007351 2 0.014
spermatid development GO:0007286 4 0.014
lipid metabolic process GO:0006629 381 0.014
cellular ion homeostasis GO:0006873 168 0.014
response to nitrogen compound GO:1901698 184 0.014
response to axon injury GO:0048678 1 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
regulation of cell adhesion GO:0030155 166 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
regulation of kinase activity GO:0043549 314 0.014
maintenance of location GO:0051235 112 0.014
cellular protein complex assembly GO:0043623 188 0.014
nervous system development GO:0007399 293 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
immune effector process GO:0002252 159 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
endocytosis GO:0006897 159 0.013
glycosylation GO:0070085 71 0.013
leukocyte activation GO:0045321 164 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
response to organic cyclic compound GO:0014070 204 0.013
regulation of cytokine production GO:0001817 232 0.013
response to organonitrogen compound GO:0010243 156 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.013
cell migration involved in gastrulation GO:0042074 1 0.013
chloride transport GO:0006821 41 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
cellular response to lipid GO:0071396 127 0.013
epidermis morphogenesis GO:0048730 3 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
nitrogen compound transport GO:0071705 191 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of protein secretion GO:0050708 86 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
receptor metabolic process GO:0043112 81 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.012
growth GO:0040007 202 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
tissue regeneration GO:0042246 3 0.012
response to external biotic stimulus GO:0043207 261 0.012
epithelial cell differentiation GO:0030855 141 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
cellular response to organic cyclic compound GO:0071407 127 0.012
cellular lipid metabolic process GO:0044255 303 0.012
glial cell migration GO:0008347 4 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
regulation of gtpase activity GO:0043087 180 0.012
golgi vesicle transport GO:0048193 80 0.012
regulation of protein stability GO:0031647 87 0.012
lipid biosynthetic process GO:0008610 177 0.012
nerve development GO:0021675 4 0.012
single organismal cell cell adhesion GO:0016337 148 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
regulation of cellular response to stress GO:0080135 244 0.012
memory GO:0007613 3 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.012
motor neuron axon guidance GO:0008045 2 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
anion transmembrane transport GO:0098656 76 0.012
protein secretion GO:0009306 98 0.012
regulation of intracellular transport GO:0032386 195 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
epithelial cell migration GO:0010631 119 0.012
epidermis development GO:0008544 59 0.012
regulation of cell cycle process GO:0010564 266 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.011
regulation of vasculature development GO:1901342 97 0.011
interspecies interaction between organisms GO:0044419 156 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
blastocyst development GO:0001824 3 0.011
neuron development GO:0048666 113 0.011
blood vessel development GO:0001568 172 0.011
mapk cascade GO:0000165 288 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
response to metal ion GO:0010038 84 0.011
neuron differentiation GO:0030182 138 0.011
inner ear morphogenesis GO:0042472 4 0.011
positive regulation of kinase activity GO:0033674 204 0.011
regulation of body fluid levels GO:0050878 99 0.011
positive regulation of immune response GO:0050778 159 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
immune system development GO:0002520 195 0.011
Zebrafish
defense response GO:0006952 315 0.011
sensory perception of smell GO:0007608 2 0.011
neuromuscular junction development GO:0007528 3 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
regulation of neurotransmitter secretion GO:0046928 3 0.011
cation transmembrane transport GO:0098655 238 0.011
basement membrane organization GO:0071711 3 0.011
regulation of metal ion transport GO:0010959 120 0.011
cerebral cortex cell migration GO:0021795 3 0.011
sphingolipid metabolic process GO:0006665 38 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
compound eye development GO:0048749 1 0.011
regulation of synaptic vesicle transport GO:1902803 3 0.011
hindbrain development GO:0030902 3 0.011
protein localization to cell surface GO:0034394 28 0.011
thymus development GO:0048538 3 0.011
response to light stimulus GO:0009416 87 0.011
regulation of immune effector process GO:0002697 91 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
cellular amide metabolic process GO:0043603 69 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
somitogenesis GO:0001756 2 0.011
osteoclast development GO:0036035 2 0.011
axis elongation GO:0003401 4 0.011
response to virus GO:0009615 126 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
protein heterotetramerization GO:0051290 3 0.011
positive regulation of proteolysis GO:0045862 142 0.011
positive regulation of cell migration GO:0030335 172 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
synaptic vesicle recycling GO:0036465 3 0.010
cdc42 protein signal transduction GO:0032488 4 0.010
regulation of endocytosis GO:0030100 72 0.010
epithelium migration GO:0090132 119 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
regulation of autophagy GO:0010506 52 0.010
associative learning GO:0008306 1 0.010
histone modification GO:0016570 251 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.010
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010
regulation of actin filament based process GO:0032970 141 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
positive regulation of smoothened signaling pathway GO:0045880 4 0.010
positive regulation of locomotion GO:0040017 186 0.010
muscle system process GO:0003012 81 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
cell cell junction organization GO:0045216 69 0.010
regulation of innate immune response GO:0045088 97 0.010
modification dependent protein catabolic process GO:0019941 209 0.010

PTTG1IP disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.122
inherited metabolic disorder DOID:655 242 0.122
lysosomal storage disease DOID:3211 47 0.041
musculoskeletal system disease DOID:17 223 0.033
central nervous system disease DOID:331 186 0.028
nervous system disease DOID:863 431 0.028
lipid storage disease DOID:9455 28 0.026
sensory system disease DOID:0050155 203 0.022
muscular disease DOID:0080000 114 0.022
muscle tissue disease DOID:66 113 0.022
disease of cellular proliferation DOID:14566 174 0.019
immune system disease DOID:2914 155 0.018
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
heart disease DOID:114 68 0.016
cardiovascular system disease DOID:1287 106 0.016
retinal disease DOID:5679 118 0.015
cerebral degeneration DOID:1443 16 0.014
brain disease DOID:936 73 0.014
connective tissue disease DOID:65 109 0.012
cancer DOID:162 167 0.012
myopathy DOID:423 104 0.011
cardiomyopathy DOID:0050700 50 0.011