Homo sapiens

7 known processes

MCM8

minichromosome maintenance complex component 8

(Aliases: MGC12866,MGC4816,dJ967N21.5,MGC119522,MGC119523,REC,C20orf154)

MCM8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication GO:0006260 116 0.420
dna repair GO:0006281 198 0.210
Mouse
double strand break repair GO:0006302 101 0.173
Mouse
post embryonic development GO:0009791 2 0.172
sister chromatid cohesion GO:0007062 24 0.155
recombinational repair GO:0000725 50 0.152
Mouse
dna dependent dna replication GO:0006261 44 0.145
chromosome segregation GO:0007059 114 0.132
cellular macromolecular complex assembly GO:0034622 324 0.116
female gamete generation GO:0007292 2 0.100
Mouse
dna replication initiation GO:0006270 6 0.094
vesicle mediated transport GO:0016192 371 0.089
dna geometric change GO:0032392 32 0.088
multicellular organismal aging GO:0010259 3 0.075
regulation of dna dependent dna replication initiation GO:0030174 3 0.065
oogenesis GO:0048477 2 0.063
dna duplex unwinding GO:0032508 30 0.060
dna recombination GO:0006310 77 0.058
Mouse Fly
meiotic chromosome segregation GO:0045132 4 0.055
organelle fission GO:0048285 149 0.055
Fly
response to abiotic stimulus GO:0009628 336 0.054
anatomical structure formation involved in morphogenesis GO:0048646 284 0.054
protein dna complex assembly GO:0065004 64 0.053
positive regulation of hydrolase activity GO:0051345 331 0.052
meiotic chromosome separation GO:0051307 3 0.050
microtubule based process GO:0007017 210 0.050
purine ribonucleoside catabolic process GO:0046130 398 0.049
positive regulation of cellular catabolic process GO:0031331 284 0.049
cellular response to dna damage stimulus GO:0006974 379 0.046
chromatin modification GO:0016568 298 0.043
amine metabolic process GO:0009308 44 0.039
negative regulation of catalytic activity GO:0043086 335 0.036
membrane organization GO:0061024 292 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.035
purine ribonucleotide catabolic process GO:0009154 404 0.033
engulfment of apoptotic cell GO:0043652 2 0.033
regulation of dna metabolic process GO:0051052 153 0.033
atp catabolic process GO:0006200 157 0.032
endocytosis GO:0006897 159 0.032
metal ion transport GO:0030001 272 0.032
protein acylation GO:0043543 138 0.031
regulation of nucleoside metabolic process GO:0009118 209 0.031
cellular amino acid metabolic process GO:0006520 116 0.031
regulation of cell cycle GO:0051726 393 0.031
positive regulation of gtp catabolic process GO:0033126 166 0.030
cellular ketone metabolic process GO:0042180 80 0.029
regulation of proteolysis GO:0030162 293 0.029
reproductive process GO:0022414 106 0.028
Mouse
ribonucleotide catabolic process GO:0009261 405 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.027
cation transport GO:0006812 331 0.026
mitotic cell cycle phase transition GO:0044772 162 0.025
positive regulation of gtpase activity GO:0043547 166 0.025
determination of adult lifespan GO:0008340 2 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
positive regulation of catabolic process GO:0009896 310 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.024
regulation of dna replication GO:0006275 68 0.024
dna conformation change GO:0071103 113 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.023
nuclear transport GO:0051169 179 0.023
purine nucleoside monophosphate metabolic process GO:0009126 186 0.023
intracellular protein transport GO:0006886 270 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
protein localization to nucleus GO:0034504 136 0.022
dna unwinding involved in dna replication GO:0006268 2 0.022
cellular amine metabolic process GO:0044106 41 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
gtp catabolic process GO:0006184 237 0.022
sister chromatid segregation GO:0000819 54 0.021
cellular component assembly involved in morphogenesis GO:0010927 73 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
protein localization to organelle GO:0033365 280 0.021
reciprocal meiotic recombination GO:0007131 4 0.021
Fly
single organism reproductive process GO:0044702 98 0.021
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.021
protein catabolic process GO:0030163 325 0.021
gtp metabolic process GO:0046039 239 0.021
negative regulation of hydrolase activity GO:0051346 182 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
cytoplasmic transport GO:0016482 379 0.020
chromatin organization GO:0006325 351 0.020
response to external biotic stimulus GO:0043207 261 0.020
regulation of intracellular transport GO:0032386 195 0.019
purine containing compound catabolic process GO:0072523 411 0.019
response to fungus GO:0009620 4 0.019
guanosine containing compound metabolic process GO:1901068 244 0.019
response to radiation GO:0009314 151 0.019
regulation of protein transport GO:0051223 213 0.019
positive regulation of apoptotic process GO:0043065 246 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
single organism membrane organization GO:0044802 268 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
hemopoiesis GO:0030097 180 0.017
developmental process involved in reproduction GO:0003006 66 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
chromosome separation GO:0051304 23 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
single organism cellular localization GO:1902580 332 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
response to other organism GO:0051707 261 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
positive regulation of developmental process GO:0051094 314 0.016
regulation of protein localization GO:0032880 296 0.016
maintenance of location GO:0051235 112 0.016
regulation of cell cycle process GO:0010564 266 0.016
nucleotide catabolic process GO:0009166 408 0.016
response to biotic stimulus GO:0009607 276 0.016
endomembrane system organization GO:0010256 196 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
chromatin assembly GO:0031497 61 0.015
cellular protein complex assembly GO:0043623 188 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
protein targeting GO:0006605 187 0.015
actin filament based process GO:0030029 224 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
oxidation reduction process GO:0055114 396 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
adult locomotory behavior GO:0008344 1 0.015
negative regulation of apoptotic process GO:0043066 316 0.014
single organism nuclear import GO:1902593 104 0.014
negative regulation of transferase activity GO:0051348 124 0.014
actomyosin structure organization GO:0031032 59 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
calcium ion transport GO:0006816 147 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
nervous system development GO:0007399 293 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
regulation of gtpase activity GO:0043087 180 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
actin cytoskeleton organization GO:0030036 207 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
positive regulation of cell death GO:0010942 263 0.014
ras protein signal transduction GO:0007265 73 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
organophosphate catabolic process GO:0046434 430 0.013
cell cycle phase transition GO:0044770 173 0.013
cell projection organization GO:0030030 252 0.013
mitotic cell cycle GO:0000278 326 0.013
growth GO:0040007 202 0.013
negative regulation of cell death GO:0060548 345 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
response to cytokine GO:0034097 232 0.013
small gtpase mediated signal transduction GO:0007264 78 0.012
protein import GO:0017038 130 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
response to hypoxia GO:0001666 96 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
response to ionizing radiation GO:0010212 65 0.012
divalent metal ion transport GO:0070838 152 0.012
peripheral nervous system development GO:0007422 2 0.012
cellular protein catabolic process GO:0044257 261 0.012
neural tube closure GO:0001843 3 0.012
rho protein signal transduction GO:0007266 26 0.012
mitotic dna integrity checkpoint GO:0044774 30 0.012
negative regulation of developmental process GO:0051093 247 0.012
system process GO:0003008 349 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
embryo development GO:0009790 123 0.011
myosin filament organization GO:0031033 2 0.011
regulation of cell differentiation GO:0045595 393 0.011
cell division GO:0051301 168 0.011
regulation of transferase activity GO:0051338 355 0.011
regulation of growth GO:0040008 165 0.011
mitotic cell cycle process GO:1903047 286 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
cell projection assembly GO:0030031 126 0.011
positive regulation of transport GO:0051050 336 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
receptor mediated endocytosis GO:0006898 84 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
cytokinesis GO:0000910 96 0.011
regulation of ion transport GO:0043269 189 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
dna packaging GO:0006323 77 0.010
regulation of mitotic cell cycle phase transition GO:1901990 118 0.010
regeneration GO:0031099 4 0.010
double strand break repair via homologous recombination GO:0000724 50 0.010
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.010
nuclear dna replication GO:0033260 6 0.010
regulation of protein catabolic process GO:0042176 155 0.010
regulation of cellular amino acid metabolic process GO:0006521 6 0.010

MCM8 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.042
carbohydrate metabolic disorder DOID:2978 55 0.042
inherited metabolic disorder DOID:655 242 0.042
immune system disease DOID:2914 155 0.030
hematopoietic system disease DOID:74 100 0.015