Homo sapiens

165 known processes

MTDH

metadherin

(Aliases: LYRIC/3D3,AEG-1,LYRIC,AEG1,3D3)

MTDH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 209 0.257
protein modification by small protein removal GO:0070646 92 0.136
multicellular organismal aging GO:0010259 3 0.134
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.133
protein deubiquitination GO:0016579 79 0.130
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.130
ubiquitin dependent protein catabolic process GO:0006511 206 0.108
protein catabolic process GO:0030163 325 0.102
protein maturation GO:0051604 233 0.100
proteasomal protein catabolic process GO:0010498 176 0.097
membrane organization GO:0061024 292 0.079
modification dependent macromolecule catabolic process GO:0043632 212 0.078
determination of adult lifespan GO:0008340 2 0.075
endomembrane system organization GO:0010256 196 0.071
positive regulation of developmental process GO:0051094 314 0.071
single organism cellular localization GO:1902580 332 0.066
response to endoplasmic reticulum stress GO:0034976 49 0.064
metal ion transport GO:0030001 272 0.063
establishment of protein localization to membrane GO:0090150 121 0.061
cell cycle phase transition GO:0044770 173 0.060
cellular amino acid metabolic process GO:0006520 116 0.057
immune system development GO:0002520 195 0.056
cellular protein catabolic process GO:0044257 261 0.054
cellular response to dna damage stimulus GO:0006974 379 0.053
single organism membrane organization GO:0044802 268 0.050
post embryonic development GO:0009791 2 0.048
protein targeting to membrane GO:0006612 42 0.048
purine nucleoside monophosphate catabolic process GO:0009128 158 0.047
nucleoside monophosphate catabolic process GO:0009125 159 0.046
negative regulation of phosphate metabolic process GO:0045936 267 0.045
protein localization to membrane GO:0072657 160 0.044
regulation of transferase activity GO:0051338 355 0.044
glycoprotein metabolic process GO:0009100 110 0.042
apoptotic signaling pathway GO:0097190 268 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.040
glycoprotein biosynthetic process GO:0009101 91 0.040
female gamete generation GO:0007292 2 0.039
cellular amine metabolic process GO:0044106 41 0.038
negative regulation of cell cycle GO:0045786 193 0.038
macromolecule glycosylation GO:0043413 63 0.037
negative regulation of catabolic process GO:0009895 104 0.036
dna damage checkpoint GO:0000077 68 0.036
single organism carbohydrate metabolic process GO:0044723 193 0.035
posttranscriptional regulation of gene expression GO:0010608 213 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
nucleobase containing compound transport GO:0015931 51 0.033
cell morphogenesis GO:0000902 296 0.033
immune response GO:0006955 307 0.033
morphogenesis of embryonic epithelium GO:0016331 4 0.033
negative regulation of mitotic cell cycle GO:0045930 102 0.033
negative regulation of cell death GO:0060548 345 0.033
dna integrity checkpoint GO:0031570 71 0.033
locomotory behavior GO:0007626 1 0.033
regulation of cell cycle phase transition GO:1901987 126 0.032
regulation of growth GO:0040008 165 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.030
regulation of protein localization GO:0032880 296 0.030
ion transmembrane transport GO:0034220 338 0.030
generation of neurons GO:0048699 152 0.030
intracellular protein transport GO:0006886 270 0.029
ribonucleoside monophosphate metabolic process GO:0009161 187 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.029
innate immune response GO:0045087 178 0.029
purine nucleoside monophosphate metabolic process GO:0009126 186 0.028
cell projection organization GO:0030030 252 0.028
nucleoside triphosphate metabolic process GO:0009141 422 0.028
negative regulation of proteolysis GO:0045861 132 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
regulation of anatomical structure morphogenesis GO:0022603 286 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
cation transmembrane transport GO:0098655 238 0.027
negative regulation of programmed cell death GO:0043069 321 0.027
lipid metabolic process GO:0006629 381 0.027
embryo development GO:0009790 123 0.027
protein localization to organelle GO:0033365 280 0.027
negative regulation of cell cycle process GO:0010948 121 0.027
amine metabolic process GO:0009308 44 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
cellular macromolecule catabolic process GO:0044265 380 0.026
cell cycle checkpoint GO:0000075 117 0.026
mitotic cell cycle phase transition GO:0044772 162 0.025
neuron projection development GO:0031175 106 0.025
protein processing GO:0016485 226 0.025
organophosphate catabolic process GO:0046434 430 0.025
translation GO:0006412 132 0.024
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.024
cation transport GO:0006812 331 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
positive regulation of cellular component organization GO:0051130 376 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.022
ribonucleoside monophosphate catabolic process GO:0009158 158 0.022
regulation of protein processing GO:0070613 150 0.022
defense response GO:0006952 315 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
vesicle mediated transport GO:0016192 371 0.022
segmentation GO:0035282 4 0.022
nucleotide biosynthetic process GO:0009165 109 0.021
negative regulation of protein processing GO:0010955 142 0.021
regulation of translation GO:0006417 89 0.021
protein targeting GO:0006605 187 0.021
nucleoside catabolic process GO:0009164 408 0.021
nucleotide catabolic process GO:0009166 408 0.021
transmembrane transport GO:0055085 399 0.021
positive regulation of meiotic cell cycle GO:0051446 2 0.021
organic hydroxy compound metabolic process GO:1901615 147 0.021
regulation of mitotic cell cycle phase transition GO:1901990 118 0.021
er nucleus signaling pathway GO:0006984 23 0.021
cellular response to cytokine stimulus GO:0071345 181 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
inorganic cation transmembrane transport GO:0098662 194 0.020
purine nucleoside catabolic process GO:0006152 398 0.019
taxis GO:0042330 157 0.019
somitogenesis GO:0001756 2 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
reproductive process GO:0022414 106 0.019
response to cytokine GO:0034097 232 0.019
regulation of cell cycle process GO:0010564 266 0.019
positive regulation of cell cycle GO:0045787 140 0.019
dephosphorylation GO:0016311 209 0.018
nervous system development GO:0007399 293 0.018
oogenesis GO:0048477 2 0.018
cellular component morphogenesis GO:0032989 314 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
regulation of cell differentiation GO:0045595 393 0.018
negative regulation of protein metabolic process GO:0051248 391 0.017
positive regulation of transport GO:0051050 336 0.017
regulation of kinase activity GO:0043549 314 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
regulation of homeostatic process GO:0032844 121 0.017
response to external biotic stimulus GO:0043207 261 0.017
carbohydrate metabolic process GO:0005975 207 0.017
meiotic chromosome segregation GO:0045132 4 0.017
ossification GO:0001503 121 0.017
rna localization GO:0006403 41 0.017
response to abiotic stimulus GO:0009628 336 0.017
adult locomotory behavior GO:0008344 1 0.017
ribonucleoside catabolic process GO:0042454 406 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
positive regulation of immune system process GO:0002684 283 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
developmental growth GO:0048589 48 0.016
ion homeostasis GO:0050801 230 0.016
positive regulation of catabolic process GO:0009896 310 0.016
atp catabolic process GO:0006200 157 0.016
renal system development GO:0072001 63 0.015
lipid biosynthetic process GO:0008610 177 0.015
positive regulation of jak stat cascade GO:0046427 35 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
divalent metal ion transport GO:0070838 152 0.015
immune effector process GO:0002252 159 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
cell development GO:0048468 328 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
chromosome segregation GO:0007059 114 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
purine containing compound catabolic process GO:0072523 411 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.015
chemical homeostasis GO:0048878 306 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
regulation of multicellular organism growth GO:0040014 8 0.014
endocytosis GO:0006897 159 0.014
ribonucleotide catabolic process GO:0009261 405 0.014
response to organic cyclic compound GO:0014070 204 0.014
divalent inorganic cation transport GO:0072511 158 0.014
mitotic cell cycle process GO:1903047 286 0.014
cation homeostasis GO:0055080 189 0.014
regulation of peptidase activity GO:0052547 180 0.014
positive regulation of growth GO:0045927 58 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
regulation of protein kinase activity GO:0045859 289 0.013
hemopoiesis GO:0030097 180 0.013
embryonic placenta development GO:0001892 1 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
metal ion homeostasis GO:0055065 169 0.013
mitotic cell cycle GO:0000278 326 0.013
glycerolipid metabolic process GO:0046486 107 0.013
regulation of behavior GO:0050795 82 0.013
atp metabolic process GO:0046034 176 0.013
regulation of protein catabolic process GO:0042176 155 0.013
cell cell signaling GO:0007267 155 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
positive regulation of transferase activity GO:0051347 227 0.013
organic anion transport GO:0015711 103 0.013
cellular homeostasis GO:0019725 196 0.013
regulation of response to external stimulus GO:0032101 222 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.012
response to extracellular stimulus GO:0009991 85 0.012
negative regulation of protein maturation GO:1903318 142 0.012
neuron development GO:0048666 113 0.012
chemotaxis GO:0006935 157 0.012
growth GO:0040007 202 0.012
actin filament based process GO:0030029 224 0.012
regulation of cell cycle GO:0051726 393 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
cellular response to interferon gamma GO:0071346 24 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
response to biotic stimulus GO:0009607 276 0.012
protein localization to nucleus GO:0034504 136 0.012
multi organism reproductive process GO:0044703 54 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
organelle fission GO:0048285 149 0.012
peptidyl serine modification GO:0018209 106 0.012
cellular response to oxygen containing compound GO:1901701 276 0.011
regulation of phosphatase activity GO:0010921 81 0.011
microtubule based process GO:0007017 210 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
cellular ketone metabolic process GO:0042180 80 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
regulation of proteolysis GO:0030162 293 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
cellular response to lipid GO:0071396 127 0.011
cytoplasmic transport GO:0016482 379 0.011
reproduction GO:0000003 63 0.011
regulation of cell development GO:0060284 161 0.011
positive regulation of response to external stimulus GO:0032103 88 0.011
oxidation reduction process GO:0055114 396 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
mitotic cell cycle checkpoint GO:0007093 68 0.011
neuromuscular junction development GO:0007528 3 0.010
regeneration GO:0031099 4 0.010
response to other organism GO:0051707 261 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
embryonic morphogenesis GO:0048598 85 0.010
urogenital system development GO:0001655 65 0.010
response to lipid GO:0033993 206 0.010
photoreceptor cell differentiation GO:0046530 2 0.010
maintenance of location GO:0051235 112 0.010
heparin metabolic process GO:0030202 1 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
establishment of rna localization GO:0051236 39 0.010

MTDH disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.050
central nervous system disease DOID:331 186 0.028
nervous system disease DOID:863 431 0.028
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.011