Homo sapiens

0 known processes

EN2

engrailed homeobox 2

EN2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron fate commitment GO:0048663 2 0.286
anatomical structure formation involved in morphogenesis GO:0048646 284 0.196
Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.157
Worm Fly
epithelium development GO:0060429 227 0.152
Zebrafish Worm
cardiovascular system development GO:0072358 262 0.121
extraocular skeletal muscle development GO:0002074 1 0.120
hindbrain development GO:0030902 3 0.110
Mouse
positive regulation of cell proliferation GO:0008284 301 0.108
tube development GO:0035295 125 0.104
Zebrafish
organ morphogenesis GO:0009887 147 0.104
Fly
cellular ketone metabolic process GO:0042180 80 0.103
organ formation GO:0048645 3 0.102
circulatory system development GO:0072359 262 0.098
cell fate determination GO:0001709 3 0.097
Fly
epithelial cell differentiation GO:0030855 141 0.097
Worm
negative regulation of multicellular organismal process GO:0051241 317 0.094
segmentation GO:0035282 4 0.092
post embryonic development GO:0009791 2 0.092
Fly
amine metabolic process GO:0009308 44 0.085
regulation of cell differentiation GO:0045595 393 0.085
nervous system development GO:0007399 293 0.085
Zebrafish Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.085
specification of organ identity GO:0010092 3 0.083
cellular amine metabolic process GO:0044106 41 0.083
negative regulation of developmental process GO:0051093 247 0.078
positive regulation of developmental process GO:0051094 314 0.076
enzyme linked receptor protein signaling pathway GO:0007167 303 0.074
secretion GO:0046903 254 0.074
regulation of cell cycle GO:0051726 393 0.072
cellular component morphogenesis GO:0032989 314 0.072
Fly
cell morphogenesis GO:0000902 296 0.071
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.071
inner ear morphogenesis GO:0042472 4 0.071
forelimb morphogenesis GO:0035136 4 0.071
embryonic morphogenesis GO:0048598 85 0.070
Zebrafish Worm
regulation of cellular amine metabolic process GO:0033238 11 0.069
regulation of locomotion GO:0040012 329 0.069
negative regulation of cell differentiation GO:0045596 171 0.069
cellular response to endogenous stimulus GO:0071495 336 0.069
regulation of anatomical structure morphogenesis GO:0022603 286 0.065
vasculature development GO:0001944 181 0.064
tissue morphogenesis GO:0048729 96 0.062
tube morphogenesis GO:0035239 95 0.062
spinal cord development GO:0021510 4 0.061
regulation of cellular amino acid metabolic process GO:0006521 6 0.061
forebrain regionalization GO:0021871 3 0.060
cell development GO:0048468 328 0.060
Zebrafish Mouse Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.060
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.059
cranial nerve development GO:0021545 4 0.058
secretion by cell GO:0032940 226 0.057
regulation of cell motility GO:2000145 299 0.055
locomotory behavior GO:0007626 1 0.055
embryonic forelimb morphogenesis GO:0035115 4 0.054
system process GO:0003008 349 0.053
regulation of cell migration GO:0030334 289 0.053
morphogenesis of embryonic epithelium GO:0016331 4 0.051
cardiac cell fate determination GO:0060913 3 0.050
negative regulation of cell death GO:0060548 345 0.050
negative regulation of protein metabolic process GO:0051248 391 0.050
stem cell differentiation GO:0048863 93 0.049
Fly
response to oxygen containing compound GO:1901700 369 0.049
cellular response to oxygen containing compound GO:1901701 276 0.048
neuron differentiation GO:0030182 138 0.047
Mouse Fly
mesenchymal cell differentiation GO:0048762 52 0.047
mitotic cell cycle GO:0000278 326 0.046
cellular amino acid metabolic process GO:0006520 116 0.046
brain development GO:0007420 97 0.046
Zebrafish Mouse Fly
forebrain generation of neurons GO:0021872 3 0.046
defense response GO:0006952 315 0.045
Fly
female gamete generation GO:0007292 2 0.045
response to lipid GO:0033993 206 0.044
regulation of cell development GO:0060284 161 0.044
positive regulation of apoptotic process GO:0043065 246 0.044
generation of neurons GO:0048699 152 0.043
Mouse Fly
anterior posterior axis specification GO:0009948 2 0.043
negative regulation of cell proliferation GO:0008285 228 0.043
positive regulation of cell death GO:0010942 263 0.043
mesenchyme development GO:0060485 59 0.043
regulation of stem cell differentiation GO:2000736 56 0.042
oogenesis GO:0048477 2 0.042
immune response GO:0006955 307 0.042
nerve development GO:0021675 4 0.042
cell cell signaling GO:0007267 155 0.042
embryonic epithelial tube formation GO:0001838 4 0.041
growth GO:0040007 202 0.041
cytoplasmic transport GO:0016482 379 0.041
negative regulation of cellular protein metabolic process GO:0032269 353 0.040
blood vessel development GO:0001568 172 0.040
regulation of dermatome development GO:0061183 3 0.039
positive regulation of cell differentiation GO:0045597 211 0.039
digestive system development GO:0055123 75 0.039
cell differentiation in spinal cord GO:0021515 1 0.039
somatic stem cell maintenance GO:0035019 4 0.039
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.039
regulation of cellular component movement GO:0051270 334 0.039
epidermis morphogenesis GO:0048730 3 0.038
positive regulation of aldosterone metabolic process GO:0032346 2 0.038
muscle structure development GO:0061061 98 0.038
positive regulation of programmed cell death GO:0043068 249 0.038
multicellular organismal aging GO:0010259 3 0.038
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.037
regulation of cytokine production GO:0001817 232 0.037
skeletal system development GO:0001501 79 0.037
negative regulation of apoptotic process GO:0043066 316 0.037
nitrogen compound transport GO:0071705 191 0.037
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.037
morphogenesis of an epithelium GO:0002009 60 0.036
positive regulation of transport GO:0051050 336 0.036
cellular macromolecule catabolic process GO:0044265 380 0.036
neurogenesis GO:0022008 169 0.036
Mouse Fly
head development GO:0060322 108 0.036
Zebrafish Mouse Fly
soft palate development GO:0060023 3 0.036
regulation of secretion GO:0051046 194 0.035
response to organic cyclic compound GO:0014070 204 0.035
motor neuron axon guidance GO:0008045 2 0.035
transmembrane transport GO:0055085 399 0.035
negative regulation of phosphorus metabolic process GO:0010563 267 0.035
negative regulation of programmed cell death GO:0043069 321 0.034
epithelial tube morphogenesis GO:0060562 38 0.034
determination of adult lifespan GO:0008340 2 0.034
protein localization to organelle GO:0033365 280 0.034
limbic system development GO:0021761 3 0.034
mesenchymal cell development GO:0014031 50 0.034
cell projection organization GO:0030030 252 0.034
Fly
cytokine production GO:0001816 247 0.034
regulation of proteolysis GO:0030162 293 0.034
lipid metabolic process GO:0006629 381 0.033
anion transport GO:0006820 161 0.033
central nervous system development GO:0007417 123 0.033
Zebrafish Mouse Fly
hard palate development GO:0060022 1 0.033
response to abiotic stimulus GO:0009628 336 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.033
positive regulation of cellular component organization GO:0051130 376 0.033
cellular response to growth factor stimulus GO:0071363 197 0.033
cell morphogenesis involved in differentiation GO:0000904 144 0.033
Fly
blastoderm segmentation GO:0007350 2 0.032
regulation of growth GO:0040008 165 0.032
cell adhesion GO:0007155 325 0.032
pituitary gland development GO:0021983 2 0.032
digestive tract development GO:0048565 75 0.032
somitogenesis GO:0001756 2 0.032
regulation of kinase activity GO:0043549 314 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.032
regulation of hormone levels GO:0010817 125 0.032
stem cell development GO:0048864 69 0.032
hair follicle morphogenesis GO:0031069 2 0.032
cardiac muscle cell contraction GO:0086003 4 0.031
heart development GO:0007507 95 0.031
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.031
embryo development GO:0009790 123 0.031
Zebrafish Worm
hematopoietic or lymphoid organ development GO:0048534 186 0.031
regulation of endopeptidase activity GO:0052548 170 0.031
positive regulation of phosphorylation GO:0042327 394 0.031
positive regulation of hydrolase activity GO:0051345 331 0.031
single organism cellular localization GO:1902580 332 0.031
regulation of secretion by cell GO:1903530 177 0.031
protein catabolic process GO:0030163 325 0.031
cation transmembrane transport GO:0098655 238 0.030
blood vessel morphogenesis GO:0048514 162 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
mesonephric duct development GO:0072177 3 0.030
actin filament based process GO:0030029 224 0.030
embryonic camera type eye development GO:0031076 2 0.030
immune system development GO:0002520 195 0.030
regulation of peptidase activity GO:0052547 180 0.029
vesicle mediated transport GO:0016192 371 0.029
forebrain neuron differentiation GO:0021879 3 0.029
negative regulation of gliogenesis GO:0014014 3 0.029
intracellular protein transport GO:0006886 270 0.029
biological adhesion GO:0022610 331 0.029
regulation of multi organism process GO:0043900 157 0.029
regulation of protein transport GO:0051223 213 0.029
negative regulation of locomotion GO:0040013 118 0.029
pancreas development GO:0031016 19 0.028
regulation of cell growth GO:0001558 135 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
ras protein signal transduction GO:0007265 73 0.028
innate immune response GO:0045087 178 0.028
negative regulation of cell cycle GO:0045786 193 0.028
formation of primary germ layer GO:0001704 42 0.028
chemical homeostasis GO:0048878 306 0.028
muscle tissue development GO:0060537 62 0.028
regulation of cellular response to stress GO:0080135 244 0.028
cardiac right ventricle morphogenesis GO:0003215 3 0.028
regulation of transferase activity GO:0051338 355 0.028
response to nitrogen compound GO:1901698 184 0.027
heart formation GO:0060914 2 0.027
cell growth GO:0016049 160 0.027
regeneration GO:0031099 4 0.027
photoreceptor cell differentiation GO:0046530 2 0.027
positive regulation of tooth mineralization GO:0070172 2 0.027
regulation of mitotic cell cycle GO:0007346 189 0.027
menstrual cycle phase GO:0022601 2 0.027
positive regulation of cell cycle GO:0045787 140 0.027
cellular response to dna damage stimulus GO:0006974 379 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
oxidation reduction process GO:0055114 396 0.026
metencephalon development GO:0022037 2 0.026
regulation of establishment of protein localization GO:0070201 242 0.026
angiogenesis GO:0001525 147 0.026
regulation of cell cycle process GO:0010564 266 0.026
regulation of response to external stimulus GO:0032101 222 0.026
epithelial cell proliferation GO:0050673 128 0.026
cellular homeostasis GO:0019725 196 0.026
positive regulation of immune system process GO:0002684 283 0.026
regulation of neural precursor cell proliferation GO:2000177 4 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
thymus development GO:0048538 3 0.026
neuromuscular junction development GO:0007528 3 0.025
reproductive process GO:0022414 106 0.025
Fly
midgut development GO:0007494 1 0.025
small gtpase mediated signal transduction GO:0007264 78 0.025
cellular response to organic cyclic compound GO:0071407 127 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.025
positive regulation of cellular component movement GO:0051272 181 0.025
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
positive regulation of protein phosphorylation GO:0001934 313 0.025
mapk cascade GO:0000165 288 0.025
negative regulation of cell development GO:0010721 48 0.025
carbohydrate metabolic process GO:0005975 207 0.025
regulation of protein localization GO:0032880 296 0.025
neural crest cell development GO:0014032 3 0.025
embryonic camera type eye formation GO:0060900 2 0.025
neural tube formation GO:0001841 3 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
embryonic camera type eye morphogenesis GO:0048596 2 0.025
purine containing compound catabolic process GO:0072523 411 0.025
positive regulation of neural precursor cell proliferation GO:2000179 2 0.025
nucleoside catabolic process GO:0009164 408 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
regulation of nucleotide metabolic process GO:0006140 269 0.024
neuroendocrine cell differentiation GO:0061101 2 0.024
regulation of nervous system development GO:0051960 88 0.024
embryonic organ development GO:0048568 36 0.023
hemopoiesis GO:0030097 180 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
cerebellum development GO:0021549 2 0.023
cation transport GO:0006812 331 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
heart morphogenesis GO:0003007 48 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
cellular response to lipid GO:0071396 127 0.023
adult locomotory behavior GO:0008344 1 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
pharynx development GO:0060465 1 0.023
cell activation GO:0001775 213 0.023
aortic valve development GO:0003176 3 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
ameboidal type cell migration GO:0001667 135 0.023
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.023
endocrine system development GO:0035270 26 0.023
regulation of neurogenesis GO:0050767 82 0.023
regulation of cell morphogenesis GO:0022604 153 0.022
response to organonitrogen compound GO:0010243 156 0.022
salivary gland morphogenesis GO:0007435 4 0.022
peripheral nervous system development GO:0007422 2 0.022
skin development GO:0043588 76 0.022
Worm
cellular lipid metabolic process GO:0044255 303 0.022
taxis GO:0042330 157 0.022
Fly
cellular response to hormone stimulus GO:0032870 125 0.022
hormone transport GO:0009914 68 0.022
neuron projection development GO:0031175 106 0.022
Fly
peptide transport GO:0015833 74 0.022
negative regulation of cell growth GO:0030308 83 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
negative regulation of stem cell differentiation GO:2000737 22 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
cell part morphogenesis GO:0032990 137 0.022
Fly
single organism carbohydrate metabolic process GO:0044723 193 0.022
muscle organ development GO:0007517 56 0.022
negative regulation of transport GO:0051051 176 0.022
wnt signaling pathway GO:0016055 156 0.022
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.022
cell projection morphogenesis GO:0048858 129 0.022
Fly
signal transduction by phosphorylation GO:0023014 297 0.022
sex determination GO:0007530 3 0.022
protein targeting GO:0006605 187 0.021
response to wounding GO:0009611 168 0.021
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
ribonucleotide catabolic process GO:0009261 405 0.021
nucleocytoplasmic transport GO:0006913 176 0.021
mitotic cell cycle process GO:1903047 286 0.021
outflow tract septum morphogenesis GO:0003148 4 0.021
positive regulation of protein transport GO:0051222 135 0.021
intracellular receptor signaling pathway GO:0030522 104 0.021
neuron development GO:0048666 113 0.021
Mouse Fly
positive regulation of mapk cascade GO:0043410 190 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
membrane organization GO:0061024 292 0.021
Worm
pattern specification process GO:0007389 43 0.021
Zebrafish Fly
anterior posterior axis specification embryo GO:0008595 2 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
embryonic viscerocranium morphogenesis GO:0048703 1 0.021
cell proliferation in forebrain GO:0021846 1 0.021
cell division GO:0051301 168 0.021
sensory organ development GO:0007423 52 0.021
negative regulation of growth GO:0045926 97 0.021
establishment of protein localization to organelle GO:0072594 172 0.021
positive regulation of cell motility GO:2000147 177 0.021
actin mediated cell contraction GO:0070252 12 0.021
positive regulation of cell development GO:0010720 92 0.020
embryonic organ morphogenesis GO:0048562 24 0.020
nuclear transport GO:0051169 179 0.020
osteoblast differentiation GO:0001649 92 0.020
primary neural tube formation GO:0014020 3 0.020
positive regulation of organelle organization GO:0010638 195 0.020
luteinizing hormone secretion GO:0032275 1 0.020
response to other organism GO:0051707 261 0.020
Fly
small molecule biosynthetic process GO:0044283 157 0.020
hormone secretion GO:0046879 65 0.020
astrocyte differentiation GO:0048708 4 0.020
response to hormone GO:0009725 175 0.020
organophosphate catabolic process GO:0046434 430 0.020
positive regulation of catabolic process GO:0009896 310 0.020
cellular protein catabolic process GO:0044257 261 0.020
ion transmembrane transport GO:0034220 338 0.020
negative regulation of cellular component movement GO:0051271 106 0.020
neuroblast proliferation GO:0007405 4 0.020
protein ubiquitination GO:0016567 314 0.020
amide transport GO:0042886 76 0.020
protein processing GO:0016485 226 0.020
response to biotic stimulus GO:0009607 276 0.020
Fly
negative regulation of cell migration GO:0030336 102 0.020
single organism reproductive process GO:0044702 98 0.020
Fly
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.019
tripartite regional subdivision GO:0007351 2 0.019
response to cytokine GO:0034097 232 0.019
regulation of mapk cascade GO:0043408 262 0.019
regulation of epithelial cell proliferation GO:0050678 113 0.019
regulation of neuron differentiation GO:0045664 70 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
regulation of protein kinase activity GO:0045859 289 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
limb bud formation GO:0060174 1 0.019
response to growth factor GO:0070848 205 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
nucleotide catabolic process GO:0009166 408 0.019
ossification GO:0001503 121 0.019
regulation of male gonad development GO:2000018 4 0.019
positive regulation of cytokine production GO:0001819 167 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
epithelium migration GO:0090132 119 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.019
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.019
neurological system process GO:0050877 163 0.019
response to external biotic stimulus GO:0043207 261 0.019
Fly
follicle stimulating hormone secretion GO:0046884 3 0.019
heart field specification GO:0003128 2 0.019
regulation of immune response GO:0050776 201 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.019
interspecies interaction between organisms GO:0044419 156 0.018
protein maturation GO:0051604 233 0.018
chromatin modification GO:0016568 298 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
chromatin organization GO:0006325 351 0.018
ion homeostasis GO:0050801 230 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.018
bmp signaling pathway involved in heart development GO:0061312 3 0.018
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.018
detection of stimulus GO:0051606 85 0.018
cation homeostasis GO:0055080 189 0.018
optic nerve development GO:0021554 2 0.018
negative regulation of mitotic cell cycle GO:0045930 102 0.018
metal ion transport GO:0030001 272 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
tissue regeneration GO:0042246 3 0.018
regulation of intracellular transport GO:0032386 195 0.018
positive regulation of locomotion GO:0040017 186 0.018
positive regulation of transferase activity GO:0051347 227 0.018
male genitalia development GO:0030539 1 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
regulation of cysteine type endopeptidase activity GO:2000116 127 0.018
oocyte differentiation GO:0009994 2 0.018
epidermis development GO:0008544 59 0.018
Worm
glial cell migration GO:0008347 4 0.018
positive regulation of proteolysis GO:0045862 142 0.018
sensory perception GO:0007600 103 0.018
canonical wnt signaling pathway GO:0060070 116 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
cerebral cortex cell migration GO:0021795 3 0.018
neuron projection regeneration GO:0031102 1 0.018
pattern specification involved in kidney development GO:0061004 1 0.018
positive regulation of hormone biosynthetic process GO:0046886 4 0.018
compound eye development GO:0048749 1 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
striated muscle tissue development GO:0014706 59 0.017
positive regulation of cell migration GO:0030335 172 0.017
actin filament based movement GO:0030048 17 0.017
immune effector process GO:0002252 159 0.017
tube closure GO:0060606 3 0.017
cellular chemical homeostasis GO:0055082 180 0.017
digestive tract morphogenesis GO:0048546 56 0.017
oocyte development GO:0048599 1 0.017
tissue migration GO:0090130 119 0.017
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 1 0.017
epithelial cell migration GO:0010631 119 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
negative regulation of protein modification process GO:0031400 200 0.017
pulmonary vein morphogenesis GO:0060577 1 0.017
purine nucleotide catabolic process GO:0006195 405 0.017
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.017
neural tube patterning GO:0021532 2 0.017
Zebrafish
chemotaxis GO:0006935 157 0.017
Fly
maintenance of location GO:0051235 112 0.017
multi organism cellular process GO:0044764 156 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
memory GO:0007613 3 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
regulation of intracellular protein transport GO:0033157 123 0.017
brain morphogenesis GO:0048854 1 0.016
leukocyte activation GO:0045321 164 0.016
muscle system process GO:0003012 81 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
striated muscle contraction GO:0006941 52 0.016
signal release GO:0023061 70 0.016
histone modification GO:0016570 251 0.016
positive regulation of odontogenesis GO:0042482 3 0.016
apoptotic signaling pathway GO:0097190 268 0.016
single organism membrane organization GO:0044802 268 0.016
Worm
rho protein signal transduction GO:0007266 26 0.016
renal system development GO:0072001 63 0.016
foramen ovale closure GO:0035922 1 0.016
single organism cell adhesion GO:0098602 179 0.016
protein localization to nucleus GO:0034504 136 0.016
positive regulation of epithelial cell proliferation GO:0050679 65 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
positive regulation of endopeptidase activity GO:0010950 84 0.016
keratinization GO:0031424 2 0.016
covalent chromatin modification GO:0016569 254 0.016
regulation of angiogenesis GO:0045765 92 0.016
ectodermal placode development GO:0071696 1 0.016
ectoderm development GO:0007398 3 0.016
regulation of ossification GO:0030278 58 0.016
protein import GO:0017038 130 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
negative regulation of cell motility GO:2000146 104 0.016
metal ion homeostasis GO:0055065 169 0.016
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
epithelial to mesenchymal transition GO:0001837 48 0.016
developmental programmed cell death GO:0010623 3 0.016
Zebrafish
embryonic eye morphogenesis GO:0048048 2 0.015
gastrulation GO:0007369 51 0.015
regulation of vasculature development GO:1901342 97 0.015
cellular cation homeostasis GO:0030003 163 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
gtp metabolic process GO:0046039 239 0.015
regulation of organ formation GO:0003156 4 0.015
response to inorganic substance GO:0010035 127 0.015
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
endodermal cell fate specification GO:0001714 4 0.015
regionalization GO:0003002 29 0.015
Zebrafish Fly
ventral spinal cord development GO:0021517 1 0.015
regulation of cardioblast differentiation GO:0051890 4 0.015
cellular component disassembly GO:0022411 92 0.015
gtp catabolic process GO:0006184 237 0.015
neural tube closure GO:0001843 3 0.015
cell cycle phase transition GO:0044770 173 0.015
behavior GO:0007610 112 0.015
cell fate commitment involved in pattern specification GO:0060581 1 0.015
regulation of neuroblast proliferation GO:1902692 3 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.015

EN2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.041
nervous system disease DOID:863 431 0.041
eye and adnexa disease DOID:1492 150 0.032
eye disease DOID:5614 149 0.032
musculoskeletal system disease DOID:17 223 0.029
disease of metabolism DOID:0014667 295 0.028
inherited metabolic disorder DOID:655 242 0.022
connective tissue disease DOID:65 109 0.021
bone disease DOID:0080001 88 0.021
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.019
retinal disease DOID:5679 118 0.019
central nervous system disease DOID:331 186 0.016