Homo sapiens

0 known processes

FZD8

frizzled homolog 8 (Drosophila)

(Aliases: FZ-8,hFZ8)

FZD8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of dermatome development GO:0061183 3 0.764
dermatome development GO:0061054 3 0.757
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.674
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.425
Human
forebrain generation of neurons GO:0021872 3 0.410
Zebrafish
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.402
Human
regulation of cell differentiation GO:0045595 393 0.367
Human
mesenchyme development GO:0060485 59 0.348
anatomical structure formation involved in morphogenesis GO:0048646 284 0.347
Human Zebrafish Mouse
negative regulation of developmental process GO:0051093 247 0.342
Human
cardiovascular system development GO:0072358 262 0.330
Human Mouse
mesenchymal cell development GO:0014031 50 0.329
forebrain regionalization GO:0021871 3 0.326
cellular amine metabolic process GO:0044106 41 0.317
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.308
Human
positive regulation of dermatome development GO:0061184 3 0.302
extraocular skeletal muscle development GO:0002074 1 0.300
mesenchymal cell differentiation GO:0048762 52 0.292
specification of organ identity GO:0010092 3 0.292
positive regulation of developmental process GO:0051094 314 0.277
Human
spinal cord development GO:0021510 4 0.270
Zebrafish
negative regulation of cell differentiation GO:0045596 171 0.260
Human
cellular ketone metabolic process GO:0042180 80 0.260
cell differentiation in spinal cord GO:0021515 1 0.254
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 303 0.242
positive regulation of cellular amine metabolic process GO:0033240 7 0.241
circulatory system development GO:0072359 262 0.232
Human Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.231
Human
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.231
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.230
cellular response to endogenous stimulus GO:0071495 336 0.226
regulation of cellular amine metabolic process GO:0033238 11 0.220
hindbrain development GO:0030902 3 0.215
stem cell differentiation GO:0048863 93 0.212
Human
amine metabolic process GO:0009308 44 0.210
organ morphogenesis GO:0009887 147 0.203
Zebrafish Fly
positive regulation of cell differentiation GO:0045597 211 0.197
Human
segmentation GO:0035282 4 0.197
Human
vasculature development GO:0001944 181 0.194
Human Mouse
digestive tract development GO:0048565 75 0.189
Human
cellular amino acid metabolic process GO:0006520 116 0.188
canonical wnt signaling pathway GO:0060070 116 0.188
Human Zebrafish Mouse
positive regulation of phosphorylation GO:0042327 394 0.188
Human Mouse
neuron fate commitment GO:0048663 2 0.186
regulation of cell development GO:0060284 161 0.180
regulation of cellular amino acid metabolic process GO:0006521 6 0.176
blood vessel morphogenesis GO:0048514 162 0.174
Mouse
cell development GO:0048468 328 0.172
Human Fly
positive regulation of protein phosphorylation GO:0001934 313 0.171
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.171
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.170
skeletal system development GO:0001501 79 0.168
positive regulation of apoptotic process GO:0043065 246 0.168
Human
formation of primary germ layer GO:0001704 42 0.166
Human
ossification GO:0001503 121 0.161
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.160
Human
regulation of locomotion GO:0040012 329 0.160
negative regulation of male gonad development GO:2000019 1 0.154
cellular component morphogenesis GO:0032989 314 0.153
Human Fly
stem cell development GO:0048864 69 0.153
Human
osteoblast differentiation GO:0001649 92 0.151
Human
wnt signaling pathway GO:0016055 156 0.150
Human Zebrafish Mouse Fly
angiogenesis GO:0001525 147 0.149
Mouse
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.149
regulation of stem cell differentiation GO:2000736 56 0.149
cell adhesion GO:0007155 325 0.149
Human
positive regulation of cell proliferation GO:0008284 301 0.148
Human
negative regulation of cell fate specification GO:0009996 3 0.148
Human
regulation of cell motility GO:2000145 299 0.147
neuron differentiation GO:0030182 138 0.138
Zebrafish Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.137
Human Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.136
Mouse
organ formation GO:0048645 3 0.133
tube development GO:0035295 125 0.131
Human
epithelium development GO:0060429 227 0.126
Human
regulation of axon guidance GO:1902667 3 0.125
mesodermal cell fate commitment GO:0001710 2 0.125
regulation of canonical wnt signaling pathway GO:0060828 88 0.124
Human
cellular response to oxygen containing compound GO:1901701 276 0.124
positive regulation of mapk cascade GO:0043410 190 0.124
Human Mouse
cellular response to growth factor stimulus GO:0071363 197 0.123
heart formation GO:0060914 2 0.122
tube morphogenesis GO:0035239 95 0.121
Human
regulation of cell migration GO:0030334 289 0.120
mapk cascade GO:0000165 288 0.118
Human Mouse
positive regulation of hydrolase activity GO:0051345 331 0.118
Human
signal transduction by phosphorylation GO:0023014 297 0.117
Human Mouse
regulation of mapk cascade GO:0043408 262 0.117
Human Mouse
cell morphogenesis GO:0000902 296 0.116
Human Fly
menstrual cycle phase GO:0022601 2 0.116
negative regulation of cell death GO:0060548 345 0.115
embryonic morphogenesis GO:0048598 85 0.113
Human Zebrafish
regulation of cellular component movement GO:0051270 334 0.112
nervous system development GO:0007399 293 0.111
Zebrafish Fly
post embryonic development GO:0009791 2 0.108
Fly
biological adhesion GO:0022610 331 0.105
Human
positive regulation of epithelial cell proliferation GO:0050679 65 0.105
Human
response to oxygen containing compound GO:1901700 369 0.105
inner ear morphogenesis GO:0042472 4 0.105
regulation of proteolysis GO:0030162 293 0.103
negative regulation of cell development GO:0010721 48 0.103
regulation of cell cycle GO:0051726 393 0.103
axis elongation GO:0003401 4 0.102
positive regulation of cellular component organization GO:0051130 376 0.102
Human
small gtpase mediated signal transduction GO:0007264 78 0.101
system process GO:0003008 349 0.101
morphogenesis of embryonic epithelium GO:0016331 4 0.100
mesodermal cell fate specification GO:0007501 2 0.099
response to growth factor GO:0070848 205 0.098
negative regulation of cell proliferation GO:0008285 228 0.098
Human
regulation of establishment of protein localization GO:0070201 242 0.097
Human
positive regulation of programmed cell death GO:0043068 249 0.097
Human
positive regulation of ossification GO:0045778 32 0.096
muscle structure development GO:0061061 98 0.095
negative regulation of cellular component organization GO:0051129 235 0.095
generation of neurons GO:0048699 152 0.095
Zebrafish Fly
regulation of wnt signaling pathway GO:0030111 123 0.094
Human
cyclic nucleotide metabolic process GO:0009187 82 0.093
Human
digestive system development GO:0055123 75 0.092
Human
cell cell signaling GO:0007267 155 0.092
Human
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.091
Human
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.090
cytoplasmic transport GO:0016482 379 0.090
Human
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.089
Human
heart morphogenesis GO:0003007 48 0.089
regulation of transferase activity GO:0051338 355 0.089
Human Mouse
positive regulation of cell development GO:0010720 92 0.087
forelimb morphogenesis GO:0035136 4 0.087
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.086
Human
heart development GO:0007507 95 0.086
brain development GO:0007420 97 0.086
Zebrafish
regulation of protein transport GO:0051223 213 0.086
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.085
Human
negative regulation of wnt signaling pathway GO:0030178 69 0.085
Human
rostrocaudal neural tube patterning GO:0021903 1 0.085
nerve development GO:0021675 4 0.084
cell proliferation in forebrain GO:0021846 1 0.084
positive regulation of transferase activity GO:0051347 227 0.083
Human Mouse
neural tube patterning GO:0021532 2 0.083
embryonic forelimb morphogenesis GO:0035115 4 0.083
regulation of nucleotide metabolic process GO:0006140 269 0.082
Human
single organism cellular localization GO:1902580 332 0.082
Human
non canonical wnt signaling pathway GO:0035567 14 0.081
Human
regulation of cell growth GO:0001558 135 0.080
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.080
Human Mouse
head development GO:0060322 108 0.080
Zebrafish
single organism cell adhesion GO:0098602 179 0.079
muscle cell fate commitment GO:0042693 4 0.079
positive regulation of cell death GO:0010942 263 0.079
Human
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.079
mesonephric duct development GO:0072177 3 0.079
regulation of growth GO:0040008 165 0.078
Human
somatic stem cell maintenance GO:0035019 4 0.078
epithelial tube morphogenesis GO:0060562 38 0.078
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.078
Human
somatic stem cell division GO:0048103 1 0.078
regulation of cellular response to stress GO:0080135 244 0.078
Human Mouse
response to wounding GO:0009611 168 0.077
Human
cell fate determination GO:0001709 3 0.077
negative regulation of programmed cell death GO:0043069 321 0.077
negative regulation of testicular blood vessel morphogenesis GO:0061369 1 0.077
positive regulation of locomotion GO:0040017 186 0.076
negative regulation of protein metabolic process GO:0051248 391 0.076
regulation of mitotic cell cycle GO:0007346 189 0.076
ameboidal type cell migration GO:0001667 135 0.076
limbic system development GO:0021761 3 0.076
tissue morphogenesis GO:0048729 96 0.076
hematopoietic or lymphoid organ development GO:0048534 186 0.076
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.076
Human
morphogenesis of an epithelium GO:0002009 60 0.075
anterior posterior axis specification GO:0009948 2 0.075
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.074
regulation of protein localization GO:0032880 296 0.074
Human
cranial nerve development GO:0021545 4 0.073
negative regulation of phosphorus metabolic process GO:0010563 267 0.073
Human
regulation of kinase activity GO:0043549 314 0.073
Human Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.073
regulation of cell adhesion GO:0030155 166 0.073
Human
somitogenesis GO:0001756 2 0.073
regulation of cell morphogenesis GO:0022604 153 0.073
positive regulation of transport GO:0051050 336 0.072
Human
regulation of cellular component biogenesis GO:0044087 281 0.072
epithelial to mesenchymal transition GO:0001837 48 0.072
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.072
epithelial cell proliferation GO:0050673 128 0.072
Human
regulation of nervous system development GO:0051960 88 0.072
single organismal cell cell adhesion GO:0016337 148 0.072
mitotic cell cycle GO:0000278 326 0.071
response to lipid GO:0033993 206 0.071
negative regulation of cellular protein metabolic process GO:0032269 353 0.070
neuroblast proliferation GO:0007405 4 0.070
chemotaxis GO:0006935 157 0.070
Fly
ras protein signal transduction GO:0007265 73 0.070
regulation of protein import into nucleus GO:0042306 78 0.070
Human
negative regulation of locomotion GO:0040013 118 0.069
immune system development GO:0002520 195 0.069
Mouse
cell projection organization GO:0030030 252 0.069
Fly
protein localization to organelle GO:0033365 280 0.069
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.069
Human
negative regulation of apoptotic process GO:0043066 316 0.068
negative regulation of stem cell differentiation GO:2000737 22 0.068
digestive tract morphogenesis GO:0048546 56 0.067
Human
negative regulation of androgen biosynthetic process GO:2000180 1 0.067
positive regulation of cell motility GO:2000147 177 0.067
regulation of organ formation GO:0003156 4 0.066
nucleocytoplasmic transport GO:0006913 176 0.066
Human
positive regulation of neural precursor cell proliferation GO:2000179 2 0.066
intracellular protein transport GO:0006886 270 0.065
Human
negative regulation of axon extension GO:0030517 2 0.065
regulation of axon extension involved in axon guidance GO:0048841 2 0.064
cellular response to dna damage stimulus GO:0006974 379 0.064
stem cell division GO:0017145 2 0.064
positive regulation of protein kinase activity GO:0045860 190 0.063
Human Mouse
neurogenesis GO:0022008 169 0.062
Zebrafish Fly
regulation of ossification GO:0030278 58 0.062
central nervous system development GO:0007417 123 0.061
Zebrafish
positive regulation of odontogenesis GO:0042482 3 0.060
gland development GO:0048732 48 0.060
Fly
regulation of nucleocytoplasmic transport GO:0046822 98 0.060
Human
embryonic camera type eye development GO:0031076 2 0.060
Zebrafish
positive regulation of catabolic process GO:0009896 310 0.060
Human
hemopoiesis GO:0030097 180 0.060
Mouse
regulation of protein kinase activity GO:0045859 289 0.060
Human Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.060
Human
regulation of cell cycle process GO:0010564 266 0.059
blood vessel development GO:0001568 172 0.059
Mouse
cardiac muscle tissue development GO:0048738 39 0.058
locomotory behavior GO:0007626 1 0.058
striated muscle tissue development GO:0014706 59 0.058
regulation of peptidase activity GO:0052547 180 0.058
negative regulation of cell cycle GO:0045786 193 0.058
neuroendocrine cell differentiation GO:0061101 2 0.057
regulation of map kinase activity GO:0043405 108 0.057
Human Mouse
negative regulation of cellular component movement GO:0051271 106 0.057
connective tissue development GO:0061448 39 0.057
rho protein signal transduction GO:0007266 26 0.057
gastrulation GO:0007369 51 0.056
Human
positive regulation of wnt signaling pathway GO:0030177 54 0.056
Human
purine ribonucleoside metabolic process GO:0046128 437 0.056
Human
taxis GO:0042330 157 0.056
Fly
regulation of endopeptidase activity GO:0052548 170 0.055
establishment of planar polarity GO:0001736 3 0.054
protein targeting to nucleus GO:0044744 104 0.054
Human
establishment of protein localization to organelle GO:0072594 172 0.054
Human
regulation of heart morphogenesis GO:2000826 4 0.053
nucleoside triphosphate metabolic process GO:0009141 422 0.053
Human
nuclear transport GO:0051169 179 0.053
Human
cartilage condensation GO:0001502 1 0.053
positive regulation of proteolysis GO:0045862 142 0.053
hard palate development GO:0060022 1 0.053
endothelial cell migration GO:0043542 86 0.052
growth GO:0040007 202 0.052
Human Fly
neuron projection development GO:0031175 106 0.052
Fly
epithelial cell differentiation GO:0030855 141 0.052
Human
cell substrate adhesion GO:0031589 132 0.052
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.052
gtp metabolic process GO:0046039 239 0.052
Human
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.052
negative regulation of catalytic activity GO:0043086 335 0.051
Human
secretion by cell GO:0032940 226 0.051
secretion GO:0046903 254 0.051
embryonic epithelial tube formation GO:0001838 4 0.051
regulation of cell cell adhesion GO:0022407 57 0.051
response to hormone GO:0009725 175 0.050
negative regulation of bmp signaling pathway GO:0030514 17 0.050
regulation of protein targeting GO:1903533 91 0.050
Human
positive regulation of cellular component movement GO:0051272 181 0.050
negative regulation of axonogenesis GO:0050771 4 0.050
purine containing compound catabolic process GO:0072523 411 0.050
Human
cellular response to hormone stimulus GO:0032870 125 0.050
neural tube formation GO:0001841 3 0.050
negative regulation of cell growth GO:0030308 83 0.050
Human
regulation of cardiac muscle tissue development GO:0055024 13 0.049
cardiac muscle cell fate commitment GO:0060923 4 0.049
ribonucleotide catabolic process GO:0009261 405 0.049
Human
regulation of stress activated mapk cascade GO:0032872 84 0.049
Human Mouse
bmp signaling pathway GO:0030509 49 0.049
forebrain development GO:0030900 26 0.048
Zebrafish
single organism nuclear import GO:1902593 104 0.048
Human
female gamete generation GO:0007292 2 0.048
protein targeting GO:0006605 187 0.048
Human
protein localization to nucleus GO:0034504 136 0.048
Human
pituitary gland development GO:0021983 2 0.047
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.047
Human
negative regulation of cardioblast differentiation GO:0051892 2 0.047
hair follicle morphogenesis GO:0031069 2 0.047
positive regulation of glucocorticoid biosynthetic process GO:0031948 1 0.047
nuclear import GO:0051170 106 0.047
Human
positive regulation of collateral sprouting GO:0048672 2 0.047
response to organic cyclic compound GO:0014070 204 0.046
carbohydrate derivative biosynthetic process GO:1901137 207 0.046
positive regulation of kinase activity GO:0033674 204 0.046
Human Mouse
regulation of secretion GO:0051046 194 0.046
muscle tissue development GO:0060537 62 0.046
positive regulation of cell migration GO:0030335 172 0.046
regulation of protein localization to nucleus GO:1900180 85 0.046
Human
response to organonitrogen compound GO:0010243 156 0.045
glycosyl compound catabolic process GO:1901658 413 0.045
Human
cellular macromolecule catabolic process GO:0044265 380 0.045
regulation of cardioblast differentiation GO:0051890 4 0.045
embryo development GO:0009790 123 0.045
Human Zebrafish
cardiocyte differentiation GO:0035051 23 0.045
regulation of neural precursor cell proliferation GO:2000177 4 0.045
regulation of intracellular transport GO:0032386 195 0.045
Human
response to biotic stimulus GO:0009607 276 0.045
Human
epithelial cell migration GO:0010631 119 0.044
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.044
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
Human
protein catabolic process GO:0030163 325 0.044
positive regulation of aldosterone metabolic process GO:0032346 2 0.044
protein import GO:0017038 130 0.044
Human
protein import into nucleus GO:0006606 104 0.044
Human
response to nitrogen compound GO:1901698 184 0.044
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.044
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.043
regulation of cytoplasmic transport GO:1903649 149 0.043
Human
pattern specification involved in kidney development GO:0061004 1 0.043
regulation of epithelial cell proliferation GO:0050678 113 0.043
Human
limb bud formation GO:0060174 1 0.043
purine nucleoside triphosphate metabolic process GO:0009144 412 0.043
Human
lipid metabolic process GO:0006629 381 0.043
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
Human
regulation of intracellular protein transport GO:0033157 123 0.042
Human
cellular response to lipid GO:0071396 127 0.042
nucleoside phosphate catabolic process GO:1901292 412 0.042
Human
receptor internalization GO:0031623 43 0.042
Human
peptidyl tyrosine modification GO:0018212 170 0.042
cell aggregation GO:0098743 1 0.042
negative regulation of growth GO:0045926 97 0.041
Human
negative regulation of testosterone biosynthetic process GO:2000225 1 0.041
nucleoside triphosphate catabolic process GO:0009143 394 0.041
Human
heart field specification GO:0003128 2 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.041
Human
negative regulation of cell adhesion GO:0007162 64 0.041
Human
chemical homeostasis GO:0048878 306 0.041
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.041
Human
cellular response to organonitrogen compound GO:0071417 124 0.041
neurological system process GO:0050877 163 0.041
negative regulation of gliogenesis GO:0014014 3 0.041
nucleoside catabolic process GO:0009164 408 0.040
Human
metencephalon development GO:0022037 2 0.040
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.040
Human
regulation of neuron differentiation GO:0045664 70 0.040
cerebral cortex cell migration GO:0021795 3 0.040
positive regulation of peptidase activity GO:0010952 88 0.040
mitotic cell cycle process GO:1903047 286 0.040
testosterone biosynthetic process GO:0061370 2 0.040
organophosphate catabolic process GO:0046434 430 0.040
Human
lung alveolus development GO:0048286 4 0.040
primary neural tube formation GO:0014020 3 0.040
positive regulation of intracellular transport GO:0032388 104 0.039
immune response GO:0006955 307 0.039
response to abiotic stimulus GO:0009628 336 0.039
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.039
Human Mouse
wound healing GO:0042060 115 0.039
Human
regulation of neurogenesis GO:0050767 82 0.039
sex determination GO:0007530 3 0.039
regulation of gtpase activity GO:0043087 180 0.039
Human
retina vasculature development in camera type eye GO:0061298 3 0.039
Human
cartilage development GO:0051216 31 0.039
cytokine production GO:0001816 247 0.039
Human
tube closure GO:0060606 3 0.039
muscle organ development GO:0007517 56 0.039
oogenesis GO:0048477 2 0.039
positive regulation of map kinase activity GO:0043406 80 0.039
Human Mouse
behavior GO:0007610 112 0.039
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.039
Human Mouse
negative regulation of protein modification process GO:0031400 200 0.038
memory GO:0007613 3 0.038
peripheral nervous system development GO:0007422 2 0.038
soft palate development GO:0060023 3 0.038
blastoderm segmentation GO:0007350 2 0.038
Human
nucleotide catabolic process GO:0009166 408 0.038
Human
determination of adult lifespan GO:0008340 2 0.038
apoptotic signaling pathway GO:0097190 268 0.038
regulation of heart induction GO:0090381 2 0.038
defense response GO:0006952 315 0.038
regulation of cytoskeleton organization GO:0051493 177 0.038
Human
regulation of vasculature development GO:1901342 97 0.038
cation transport GO:0006812 331 0.038
positive regulation of protein transport GO:0051222 135 0.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.037
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.037
regulation of cysteine type endopeptidase activity GO:2000116 127 0.037
multicellular organismal aging GO:0010259 3 0.037
cell division GO:0051301 168 0.037
cellular response to nitrogen compound GO:1901699 144 0.037
neuron development GO:0048666 113 0.037
Fly
purine nucleoside catabolic process GO:0006152 398 0.037
Human
cell type specific apoptotic process GO:0097285 125 0.036
Human
neuromuscular junction development GO:0007528 3 0.036
epidermis development GO:0008544 59 0.036
Human
hindlimb morphogenesis GO:0035137 2 0.036
regulation of response to external stimulus GO:0032101 222 0.036
neuronal stem cell division GO:0036445 1 0.036
motor neuron axon guidance GO:0008045 2 0.036
Fly
regulation of cell projection organization GO:0031344 107 0.036
positive regulation of tooth mineralization GO:0070172 2 0.036
neural crest cell development GO:0014032 3 0.036
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.036
Human
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.036
morphogenesis of a polarized epithelium GO:0001738 3 0.035
regulation of male gonad development GO:2000018 4 0.035
regulation of epithelial cell migration GO:0010632 93 0.035
heart induction GO:0003129 4 0.035
organ induction GO:0001759 4 0.035
tissue migration GO:0090130 119 0.035
negative regulation of protein phosphorylation GO:0001933 140 0.035
embryonic organ morphogenesis GO:0048562 24 0.035
Zebrafish
embryonic organ development GO:0048568 36 0.035
Zebrafish
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.035
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.035
positive regulation of stress activated mapk cascade GO:0032874 60 0.035
Human Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.035
Human
activation of protein kinase activity GO:0032147 90 0.034
epithelium migration GO:0090132 119 0.034
purine ribonucleoside catabolic process GO:0046130 398 0.034
Human
purine nucleotide catabolic process GO:0006195 405 0.034
Human
cell growth GO:0016049 160 0.034
Human Fly
positive regulation of cytoplasmic transport GO:1903651 82 0.034
guanosine containing compound catabolic process GO:1901069 239 0.034
Human
anterior posterior axis specification embryo GO:0008595 2 0.034
Human
sensory organ development GO:0007423 52 0.033
Human Zebrafish Fly
response to external biotic stimulus GO:0043207 261 0.033
Human
regulation of response to wounding GO:1903034 101 0.033
purine ribonucleotide catabolic process GO:0009154 404 0.033
Human
regulation of nucleoside metabolic process GO:0009118 209 0.033
Human
regionalization GO:0003002 29 0.033
Human Zebrafish
regulation of secretion by cell GO:1903530 177 0.033
cellular response to cytokine stimulus GO:0071345 181 0.033
stress activated protein kinase signaling cascade GO:0031098 94 0.033
Human Mouse
regulation of purine nucleotide catabolic process GO:0033121 205 0.033
Human
negative regulation of non canonical wnt signaling pathway GO:2000051 1 0.032
purine nucleoside triphosphate catabolic process GO:0009146 392 0.032
Human
regulation of actin filament based process GO:0032970 141 0.032
Human
response to other organism GO:0051707 261 0.032
Human
cerebellum development GO:0021549 2 0.032
cell fate commitment involved in formation of primary germ layer GO:0060795 6 0.032
Human
endothelial cell proliferation GO:0001935 65 0.032
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.032
Human Mouse
regulation of osteoblast differentiation GO:0045667 38 0.032
regulation of catenin import into nucleus GO:0035412 18 0.032
Human
stress activated mapk cascade GO:0051403 93 0.032
Human Mouse
regulation of behavior GO:0050795 82 0.032
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.032
hippocampus development GO:0021766 1 0.032
embryonic camera type eye morphogenesis GO:0048596 2 0.032
Zebrafish
positive regulation of endopeptidase activity GO:0010950 84 0.032
receptor metabolic process GO:0043112 81 0.031
Human
positive regulation of cellular catabolic process GO:0031331 284 0.031
Human
positive regulation of cell cycle GO:0045787 140 0.031
regulation of nucleotide catabolic process GO:0030811 205 0.031
Human
actin filament based process GO:0030029 224 0.031
Human
regulation of muscle organ development GO:0048634 27 0.031
regulation of receptor internalization GO:0002090 15 0.031
Human
positive regulation of cortisol biosynthetic process GO:2000066 1 0.031
cardioblast cell fate commitment GO:0042684 1 0.031
regulation of cytokine production GO:0001817 232 0.031
Human
negative regulation of cell migration GO:0030336 102 0.031
positive regulation of nervous system development GO:0051962 54 0.031
response to cytokine GO:0034097 232 0.031
chordate embryonic development GO:0043009 34 0.031
endocrine system development GO:0035270 26 0.031
establishment of tissue polarity GO:0007164 3 0.031
negative regulation of mitotic cell cycle GO:0045930 102 0.030
regulation of endothelial cell proliferation GO:0001936 56 0.030
cellular response to organic cyclic compound GO:0071407 127 0.030
regulation of neuron projection development GO:0010975 57 0.030
gtp catabolic process GO:0006184 237 0.030
Human
forebrain neuron differentiation GO:0021879 3 0.030
Zebrafish
renal system development GO:0072001 63 0.030
endodermal cell fate commitment GO:0001711 4 0.030
regulation of homeostatic process GO:0032844 121 0.030
neurotransmitter secretion GO:0007269 4 0.030
kidney development GO:0001822 53 0.030
startle response GO:0001964 3 0.030
regulation of hormone levels GO:0010817 125 0.030
embryonic eye morphogenesis GO:0048048 2 0.030
Zebrafish
regulation of protein catabolic process GO:0042176 155 0.030
positive regulation of endothelial cell proliferation GO:0001938 37 0.029
guanosine containing compound metabolic process GO:1901068 244 0.029
Human
regulation of epithelial to mesenchymal transition GO:0010717 37 0.029
cell part morphogenesis GO:0032990 137 0.029
Fly
regulation of bmp signaling pathway GO:0030510 27 0.029
sensory organ morphogenesis GO:0090596 21 0.029
Zebrafish
protein modification by small protein conjugation GO:0032446 342 0.029
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.029
bone development GO:0060348 26 0.029
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.029

FZD8 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.071
connective tissue disease DOID:65 109 0.043
sensory system disease DOID:0050155 203 0.038
Human
nervous system disease DOID:863 431 0.038
Human
eye and adnexa disease DOID:1492 150 0.033
Human
eye disease DOID:5614 149 0.033
Human