Homo sapiens

11 known processes

PMM1

phosphomannomutase 1

(Aliases: Sec53)

PMM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
segmentation GO:0035282 4 0.094
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.086
cellular ketone metabolic process GO:0042180 80 0.069
organophosphate catabolic process GO:0046434 430 0.065
lipid metabolic process GO:0006629 381 0.059
response to fungus GO:0009620 4 0.057
blastoderm segmentation GO:0007350 2 0.056
amine metabolic process GO:0009308 44 0.055
cytoplasmic transport GO:0016482 379 0.055
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.054
positive regulation of hydrolase activity GO:0051345 331 0.054
oogenesis GO:0048477 2 0.054
anterior posterior axis specification GO:0009948 2 0.052
cellular amino acid metabolic process GO:0006520 116 0.052
regulation of nucleoside metabolic process GO:0009118 209 0.052
oocyte differentiation GO:0009994 2 0.049
cellular amine metabolic process GO:0044106 41 0.048
defense response to fungus GO:0050832 4 0.048
regulation of nucleotide metabolic process GO:0006140 269 0.048
cofactor metabolic process GO:0051186 87 0.047
atp metabolic process GO:0046034 176 0.047
purine ribonucleoside metabolic process GO:0046128 437 0.047
purine nucleoside triphosphate metabolic process GO:0009144 412 0.047
regulation of purine nucleotide metabolic process GO:1900542 264 0.047
ribonucleotide catabolic process GO:0009261 405 0.046
glycosyl compound catabolic process GO:1901658 413 0.046
intracellular mrna localization GO:0008298 1 0.045
oocyte development GO:0048599 1 0.044
single organism carbohydrate metabolic process GO:0044723 193 0.044
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
positive regulation of nucleotide catabolic process GO:0030813 185 0.042
purine ribonucleotide catabolic process GO:0009154 404 0.042
organic hydroxy compound metabolic process GO:1901615 147 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
positive regulation of nucleotide metabolic process GO:0045981 230 0.038
regulation of nucleotide catabolic process GO:0030811 205 0.038
guanosine containing compound catabolic process GO:1901069 239 0.037
protein localization to organelle GO:0033365 280 0.037
intracellular protein transport GO:0006886 270 0.036
purine containing compound catabolic process GO:0072523 411 0.036
purine ribonucleoside catabolic process GO:0046130 398 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
nucleoside phosphate catabolic process GO:1901292 412 0.035
positive regulation of catabolic process GO:0009896 310 0.035
anterior posterior axis specification embryo GO:0008595 2 0.035
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
cellular macromolecule catabolic process GO:0044265 380 0.034
positive regulation of nucleoside metabolic process GO:0045979 186 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
nucleotide catabolic process GO:0009166 408 0.034
organonitrogen compound biosynthetic process GO:1901566 200 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.034
negative regulation of protein metabolic process GO:0051248 391 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.033
post embryonic development GO:0009791 2 0.033
ribonucleoside catabolic process GO:0042454 406 0.033
single organism cellular localization GO:1902580 332 0.033
purine nucleotide catabolic process GO:0006195 405 0.032
nucleoside catabolic process GO:0009164 408 0.032
female gamete generation GO:0007292 2 0.031
cellular lipid metabolic process GO:0044255 303 0.031
ribonucleoside monophosphate metabolic process GO:0009161 187 0.031
ribonucleoside monophosphate catabolic process GO:0009158 158 0.030
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
purine nucleoside monophosphate catabolic process GO:0009128 158 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
regulation of postsynaptic membrane potential GO:0060078 1 0.030
secretion by cell GO:0032940 226 0.030
regulation of membrane potential GO:0042391 95 0.029
regulation of multi organism process GO:0043900 157 0.029
small gtpase mediated signal transduction GO:0007264 78 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
response to oxygen containing compound GO:1901700 369 0.028
small molecule biosynthetic process GO:0044283 157 0.028
cellular component morphogenesis GO:0032989 314 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
cell projection organization GO:0030030 252 0.027
regulation of transferase activity GO:0051338 355 0.027
coenzyme metabolic process GO:0006732 65 0.027
purine nucleoside monophosphate metabolic process GO:0009126 186 0.027
microtubule cytoskeleton organization GO:0000226 176 0.026
lipid biosynthetic process GO:0008610 177 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
glycerolipid metabolic process GO:0046486 107 0.026
modification dependent macromolecule catabolic process GO:0043632 212 0.026
gtp metabolic process GO:0046039 239 0.026
retrograde transport endosome to golgi GO:0042147 45 0.026
defense response GO:0006952 315 0.025
organophosphate biosynthetic process GO:0090407 163 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
nucleoside triphosphate catabolic process GO:0009143 394 0.025
atp catabolic process GO:0006200 157 0.025
response to external biotic stimulus GO:0043207 261 0.025
vesicle mediated transport GO:0016192 371 0.025
locomotory behavior GO:0007626 1 0.025
microtubule based process GO:0007017 210 0.025
response to other organism GO:0051707 261 0.024
cell morphogenesis GO:0000902 296 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
small molecule catabolic process GO:0044282 92 0.024
methylation GO:0032259 106 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
regulation of cell cycle GO:0051726 393 0.024
response to abiotic stimulus GO:0009628 336 0.024
regulation of protein localization GO:0032880 296 0.024
protein targeting GO:0006605 187 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
enzyme linked receptor protein signaling pathway GO:0007167 303 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
regulation of protein transport GO:0051223 213 0.023
mitotic cell cycle process GO:1903047 286 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.023
nucleoside monophosphate catabolic process GO:0009125 159 0.023
cellular protein catabolic process GO:0044257 261 0.023
protein oligomerization GO:0051259 173 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
secretion GO:0046903 254 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
macromolecule methylation GO:0043414 97 0.023
regeneration GO:0031099 4 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
protein ubiquitination GO:0016567 314 0.022
nervous system development GO:0007399 293 0.022
ras protein signal transduction GO:0007265 73 0.022
response to biotic stimulus GO:0009607 276 0.022
guanosine containing compound metabolic process GO:1901068 244 0.022
dephosphorylation GO:0016311 209 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
sulfur compound metabolic process GO:0006790 101 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
oxidation reduction process GO:0055114 396 0.022
negative regulation of hydrolase activity GO:0051346 182 0.021
gtp catabolic process GO:0006184 237 0.021
cation transport GO:0006812 331 0.021
regulation of cell cycle process GO:0010564 266 0.021
multicellular organismal aging GO:0010259 3 0.021
regulation of protein kinase activity GO:0045859 289 0.021
chemotaxis GO:0006935 157 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.020
mapk cascade GO:0000165 288 0.020
rho protein signal transduction GO:0007266 26 0.020
negative regulation of protein modification process GO:0031400 200 0.020
protein maturation GO:0051604 233 0.020
system process GO:0003008 349 0.020
regulation of intracellular transport GO:0032386 195 0.020
ubiquitin dependent protein catabolic process GO:0006511 206 0.020
taxis GO:0042330 157 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
protein catabolic process GO:0030163 325 0.019
regulation of atpase activity GO:0043462 25 0.019
golgi vesicle transport GO:0048193 80 0.019
endosomal transport GO:0016197 129 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
divalent metal ion transport GO:0070838 152 0.019
response to axon injury GO:0048678 1 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
transmembrane transport GO:0055085 399 0.019
organic acid biosynthetic process GO:0016053 97 0.019
cell activation GO:0001775 213 0.018
regulation of proteolysis GO:0030162 293 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
membrane organization GO:0061024 292 0.018
cellular homeostasis GO:0019725 196 0.018
neuromuscular junction development GO:0007528 3 0.018
metal ion transport GO:0030001 272 0.018
cell development GO:0048468 328 0.018
regulation of atp catabolic process GO:1903289 25 0.018
positive regulation of transport GO:0051050 336 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
apoptotic signaling pathway GO:0097190 268 0.017
mitotic cell cycle GO:0000278 326 0.017
organelle assembly GO:0070925 176 0.017
adult locomotory behavior GO:0008344 1 0.017
protein processing GO:0016485 226 0.017
regulation of peptidase activity GO:0052547 180 0.017
actin cytoskeleton organization GO:0030036 207 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
determination of adult lifespan GO:0008340 2 0.016
regulation of response to external stimulus GO:0032101 222 0.016
positive regulation of developmental process GO:0051094 314 0.016
protein methylation GO:0006479 74 0.016
defense response to other organism GO:0098542 129 0.016
neurotransmitter secretion GO:0007269 4 0.016
calcium ion transport GO:0006816 147 0.016
neuroblast proliferation GO:0007405 4 0.016
memory GO:0007613 3 0.016
cell part morphogenesis GO:0032990 137 0.016
regulation of cell migration GO:0030334 289 0.016
alcohol metabolic process GO:0006066 114 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
cellular chemical homeostasis GO:0055082 180 0.016
regulation of mapk cascade GO:0043408 262 0.016
cell cell signaling GO:0007267 155 0.016
positive regulation of organelle organization GO:0010638 195 0.016
negative regulation of cell death GO:0060548 345 0.016
immune response GO:0006955 307 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
protein homooligomerization GO:0051260 100 0.015
regulation of cell differentiation GO:0045595 393 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
regulation of secretion GO:0051046 194 0.015
biological adhesion GO:0022610 331 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
peripheral nervous system development GO:0007422 2 0.015
interspecies interaction between organisms GO:0044419 156 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
regulation of cytokine production GO:0001817 232 0.015
regulation of cellular response to stress GO:0080135 244 0.015
single organism membrane organization GO:0044802 268 0.015
compound eye development GO:0048749 1 0.015
growth GO:0040007 202 0.015
cellular cation homeostasis GO:0030003 163 0.015
sensory perception of pain GO:0019233 4 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
anion transport GO:0006820 161 0.015
positive regulation of cell death GO:0010942 263 0.014
sulfur compound biosynthetic process GO:0044272 38 0.014
mitochondrion organization GO:0007005 156 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
regulation of kinase activity GO:0043549 314 0.014
regulation of cell motility GO:2000145 299 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
cell division GO:0051301 168 0.014
spermatid differentiation GO:0048515 4 0.014
positive regulation of immune system process GO:0002684 283 0.014
generation of neurons GO:0048699 152 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
negative regulation of cell cycle GO:0045786 193 0.014
negative regulation of multi organism process GO:0043901 92 0.014
positive regulation of programmed cell death GO:0043068 249 0.013
regulation of immune response GO:0050776 201 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
rhythmic behavior GO:0007622 2 0.013
ion transmembrane transport GO:0034220 338 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
cell growth GO:0016049 160 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
positive regulation of transferase activity GO:0051347 227 0.013
regulation of protein processing GO:0070613 150 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
neurogenesis GO:0022008 169 0.013
regulation of secretion by cell GO:1903530 177 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
carboxylic acid biosynthetic process GO:0046394 97 0.013
cation homeostasis GO:0055080 189 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
metencephalon development GO:0022037 2 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
negative regulation of transferase activity GO:0051348 124 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
positive regulation of kinase activity GO:0033674 204 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
divalent inorganic cation transport GO:0072511 158 0.012
cell projection assembly GO:0030031 126 0.012
negative regulation of transport GO:0051051 176 0.012
associative learning GO:0008306 1 0.012
cell projection morphogenesis GO:0048858 129 0.012
mitotic nuclear division GO:0007067 119 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of protein maturation GO:1903317 150 0.012
spermatid development GO:0007286 4 0.012
cell cycle phase transition GO:0044770 173 0.012
regulation of growth GO:0040008 165 0.012
hindbrain development GO:0030902 3 0.012
actin filament based movement GO:0030048 17 0.012
dna repair GO:0006281 198 0.012
response to growth factor GO:0070848 205 0.012
actin filament based process GO:0030029 224 0.012
response to decreased oxygen levels GO:0036293 96 0.012
response to cytokine GO:0034097 232 0.012
regulation of neurotransmitter secretion GO:0046928 3 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
regulation of dna metabolic process GO:0051052 153 0.012
positive regulation of atpase activity GO:0032781 19 0.012
single organism reproductive process GO:0044702 98 0.012
monosaccharide metabolic process GO:0005996 74 0.012
maintenance of location GO:0051235 112 0.012
organ formation GO:0048645 3 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
mitochondrial transport GO:0006839 60 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
negative regulation of organelle organization GO:0010639 126 0.012
viral life cycle GO:0019058 132 0.012
chromatin organization GO:0006325 351 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
regulation of atp metabolic process GO:1903578 29 0.012
response to hormone GO:0009725 175 0.012
fatty acid metabolic process GO:0006631 115 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
endomembrane system organization GO:0010256 196 0.012
protein localization to membrane GO:0072657 160 0.012
embryo development GO:0009790 123 0.012
neurological system process GO:0050877 163 0.012
negative regulation of peptidase activity GO:0010466 91 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
limbic system development GO:0021761 3 0.011
glycerolipid biosynthetic process GO:0045017 51 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
regulation of gtpase activity GO:0043087 180 0.011
response to organic cyclic compound GO:0014070 204 0.011
neuron development GO:0048666 113 0.011
exocytosis GO:0006887 71 0.011
cilium organization GO:0044782 68 0.011
innate immune response GO:0045087 178 0.011
cerebellum development GO:0021549 2 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
regulation of locomotion GO:0040012 329 0.011
positive regulation of protein transport GO:0051222 135 0.011
regulation of protein complex assembly GO:0043254 147 0.011
glycoprotein metabolic process GO:0009100 110 0.011
steroid metabolic process GO:0008202 94 0.011
response to oxidative stress GO:0006979 121 0.011
cellular response to nutrient levels GO:0031669 69 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
negative regulation of protein maturation GO:1903318 142 0.011
inner ear morphogenesis GO:0042472 4 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
spinal cord development GO:0021510 4 0.011
reproductive process GO:0022414 106 0.011
mating GO:0007618 1 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
organic anion transport GO:0015711 103 0.011
visual behavior GO:0007632 2 0.011
cation transmembrane transport GO:0098655 238 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
epithelium development GO:0060429 227 0.011
rna processing GO:0006396 255 0.011
nerve development GO:0021675 4 0.011
cytokinesis GO:0000910 96 0.011
epithelial cell differentiation GO:0030855 141 0.011
response to lipid GO:0033993 206 0.011
regulation of protein catabolic process GO:0042176 155 0.011
regulation of actin filament based process GO:0032970 141 0.011
neural tube formation GO:0001841 3 0.011
neuron projection development GO:0031175 106 0.011
chemical homeostasis GO:0048878 306 0.010
striated muscle contraction GO:0006941 52 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.010
cellular modified amino acid metabolic process GO:0006575 64 0.010
peptidyl tyrosine modification GO:0018212 170 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
negative regulation of protein processing GO:0010955 142 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
response to oxygen levels GO:0070482 100 0.010
calcium ion homeostasis GO:0055074 122 0.010
cell fate determination GO:0001709 3 0.010
salivary gland morphogenesis GO:0007435 4 0.010
cell adhesion GO:0007155 325 0.010
positive regulation of cytokine production GO:0001819 167 0.010
circadian behavior GO:0048512 2 0.010
cellular protein complex assembly GO:0043623 188 0.010
epithelial cell proliferation GO:0050673 128 0.010
peptidyl serine modification GO:0018209 106 0.010
neuron differentiation GO:0030182 138 0.010
response to inorganic substance GO:0010035 127 0.010
developmental programmed cell death GO:0010623 3 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
nucleoside phosphate biosynthetic process GO:1901293 109 0.010
tissue regeneration GO:0042246 3 0.010
actin mediated cell contraction GO:0070252 12 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
negative regulation of proteolysis GO:0045861 132 0.010

PMM1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.045
Human
inherited metabolic disorder DOID:655 242 0.026
Human
musculoskeletal system disease DOID:17 223 0.023
disease of cellular proliferation DOID:14566 174 0.022
cancer DOID:162 167 0.021
organ system cancer DOID:0050686 164 0.021
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
central nervous system disease DOID:331 186 0.018
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
neurodegenerative disease DOID:1289 102 0.014
muscular disease DOID:0080000 114 0.014
muscle tissue disease DOID:66 113 0.014
cardiovascular system disease DOID:1287 106 0.013
myopathy DOID:423 104 0.012
disease of mental health DOID:150 70 0.012
amino acid metabolic disorder DOID:9252 50 0.012
carbohydrate metabolic disorder DOID:2978 55 0.011
Human
connective tissue disease DOID:65 109 0.011
immune system disease DOID:2914 155 0.010
retinal disease DOID:5679 118 0.010