Homo sapiens

13 known processes

SCN2A

sodium channel, voltage-gated, type II, alpha subunit

(Aliases: HBSCII,Nav1.2,EIEE11,Na(v)1.2,HBA,HBSCI,SCN2A2,SCN2A1,NAC2,BFIC3)

SCN2A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transmission of nerve impulse GO:0051969 2 0.297
transmembrane transport GO:0055085 399 0.257
Human Mouse Rat
ion transmembrane transport GO:0034220 338 0.199
Human Mouse Rat
negative regulation of transmission of nerve impulse GO:0051970 1 0.146
system process GO:0003008 349 0.135
Human Rat
locomotory behavior GO:0007626 1 0.125
cation transport GO:0006812 331 0.124
Human Mouse Rat
regulation of acrosome reaction GO:0060046 4 0.118
inorganic ion transmembrane transport GO:0098660 231 0.116
Human Mouse Rat
muscle contraction GO:0006936 73 0.114
Human
cellular amino acid metabolic process GO:0006520 116 0.113
g protein coupled receptor signaling pathway GO:0007186 207 0.112
cellular ketone metabolic process GO:0042180 80 0.102
positive regulation of acrosome reaction GO:2000344 4 0.099
inorganic cation transmembrane transport GO:0098662 194 0.097
Human Mouse Rat
gamma aminobutyric acid signaling pathway GO:0007214 3 0.089
cellular response to histamine GO:0071420 3 0.088
neurological system process GO:0050877 163 0.084
Rat
metal ion transport GO:0030001 272 0.082
Human Mouse Rat
regulation of cellular ketone metabolic process GO:0010565 50 0.081
regulation of cellular amino acid metabolic process GO:0006521 6 0.078
cellular amine metabolic process GO:0044106 41 0.077
cardiac muscle cell contraction GO:0086003 4 0.076
positive regulation of cellular amine metabolic process GO:0033240 7 0.073
positive regulation of transport GO:0051050 336 0.067
vesicle mediated transport GO:0016192 371 0.066
cation transmembrane transport GO:0098655 238 0.066
Human Mouse Rat
amine metabolic process GO:0009308 44 0.065
regulation of secretion by cell GO:1903530 177 0.064
post embryonic development GO:0009791 2 0.063
monovalent inorganic cation transport GO:0015672 128 0.063
Human Mouse Rat
regulation of cellular amine metabolic process GO:0033238 11 0.061
nervous system development GO:0007399 293 0.059
Mouse Rat
memory GO:0007613 3 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
regulation of membrane potential GO:0042391 95 0.056
Human Rat
neurotransmitter secretion GO:0007269 4 0.056
action potential GO:0001508 34 0.056
Rat
anion transport GO:0006820 161 0.055
multicellular organismal signaling GO:0035637 34 0.055
Human Rat
startle response GO:0001964 3 0.055
regulation of cellular component biogenesis GO:0044087 281 0.054
secretion GO:0046903 254 0.053
small gtpase mediated signal transduction GO:0007264 78 0.053
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.051
regulation of secretion GO:0051046 194 0.051
regulation of neurotransmitter secretion GO:0046928 3 0.051
cardiac muscle contraction GO:0060048 34 0.050
Human
ras protein signal transduction GO:0007265 73 0.049
nucleoside triphosphate metabolic process GO:0009141 422 0.047
positive regulation of cellular component organization GO:0051130 376 0.046
muscle system process GO:0003012 81 0.046
Human
nucleoside catabolic process GO:0009164 408 0.046
actin filament based process GO:0030029 224 0.045
regulation of ion transport GO:0043269 189 0.045
Human Mouse Rat
secretion by cell GO:0032940 226 0.045
ribonucleotide catabolic process GO:0009261 405 0.044
glycosyl compound catabolic process GO:1901658 413 0.044
purine nucleoside triphosphate catabolic process GO:0009146 392 0.043
purine nucleoside triphosphate metabolic process GO:0009144 412 0.043
positive regulation of synaptic transmission GO:0050806 4 0.043
ribonucleoside catabolic process GO:0042454 406 0.042
chemical homeostasis GO:0048878 306 0.042
Human
response to abiotic stimulus GO:0009628 336 0.042
Mouse
neuromuscular junction development GO:0007528 3 0.041
purine ribonucleotide catabolic process GO:0009154 404 0.041
associative learning GO:0008306 1 0.041
cell adhesion GO:0007155 325 0.040
cellular lipid metabolic process GO:0044255 303 0.040
lipid metabolic process GO:0006629 381 0.040
cellular potassium ion transport GO:0071804 60 0.039
actin mediated cell contraction GO:0070252 12 0.039
ribonucleoside triphosphate catabolic process GO:0009203 391 0.038
potassium ion transmembrane transport GO:0071805 60 0.038
regulation of hormone levels GO:0010817 125 0.038
purine ribonucleoside metabolic process GO:0046128 437 0.037
positive regulation of phosphorylation GO:0042327 394 0.037
regulation of synaptic plasticity GO:0048167 3 0.037
single organism membrane organization GO:0044802 268 0.037
response to nitrogen compound GO:1901698 184 0.037
purine nucleotide catabolic process GO:0006195 405 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.037
biological adhesion GO:0022610 331 0.037
purine containing compound catabolic process GO:0072523 411 0.036
ribonucleoside triphosphate metabolic process GO:0009199 412 0.036
purine nucleoside catabolic process GO:0006152 398 0.036
neurogenesis GO:0022008 169 0.036
regulation of system process GO:0044057 101 0.036
Human
purine ribonucleoside catabolic process GO:0046130 398 0.036
cell projection organization GO:0030030 252 0.036
multicellular organismal aging GO:0010259 3 0.036
nucleotide catabolic process GO:0009166 408 0.035
nucleoside triphosphate catabolic process GO:0009143 394 0.035
guanosine containing compound metabolic process GO:1901068 244 0.035
membrane organization GO:0061024 292 0.035
cell development GO:0048468 328 0.035
regulation of response to external stimulus GO:0032101 222 0.034
female gamete generation GO:0007292 2 0.034
protein localization to organelle GO:0033365 280 0.034
behavior GO:0007610 112 0.034
oogenesis GO:0048477 2 0.034
regulation of actin filament based process GO:0032970 141 0.034
regulation of ion transmembrane transport GO:0034765 132 0.033
Human Mouse Rat
response to organonitrogen compound GO:0010243 156 0.033
blood circulation GO:0008015 113 0.033
Human
response to oxygen containing compound GO:1901700 369 0.033
regulation of homeostatic process GO:0032844 121 0.032
Human
organophosphate catabolic process GO:0046434 430 0.032
carbohydrate derivative biosynthetic process GO:1901137 207 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
determination of adult lifespan GO:0008340 2 0.032
cellular component morphogenesis GO:0032989 314 0.031
cell morphogenesis GO:0000902 296 0.031
cellular chemical homeostasis GO:0055082 180 0.031
synaptic transmission GO:0007268 61 0.031
transmission of nerve impulse GO:0019226 11 0.031
Rat
peripheral nervous system development GO:0007422 2 0.030
ion homeostasis GO:0050801 230 0.030
Human
regulation of cellular component movement GO:0051270 334 0.030
single organism cellular localization GO:1902580 332 0.030
striated muscle contraction GO:0006941 52 0.030
Human
nitrogen compound transport GO:0071705 191 0.030
mapk cascade GO:0000165 288 0.029
mitotic cell cycle GO:0000278 326 0.029
potassium ion transport GO:0006813 62 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.029
regulation of transmembrane transport GO:0034762 139 0.028
Human Mouse Rat
positive regulation of hydrolase activity GO:0051345 331 0.028
cytoplasmic transport GO:0016482 379 0.028
divalent inorganic cation transport GO:0072511 158 0.028
positive regulation of nucleotide metabolic process GO:0045981 230 0.028
gtp catabolic process GO:0006184 237 0.028
rho protein signal transduction GO:0007266 26 0.028
generation of neurons GO:0048699 152 0.028
rhythmic behavior GO:0007622 2 0.028
positive regulation of protein phosphorylation GO:0001934 313 0.027
circulatory system process GO:0003013 113 0.027
Human
endomembrane system organization GO:0010256 196 0.027
regulation of nucleoside metabolic process GO:0009118 209 0.027
adult locomotory behavior GO:0008344 1 0.027
response to organic cyclic compound GO:0014070 204 0.027
guanosine containing compound catabolic process GO:1901069 239 0.027
neuron differentiation GO:0030182 138 0.026
peptidyl tyrosine phosphorylation GO:0018108 170 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
actin filament based movement GO:0030048 17 0.026
cellular homeostasis GO:0019725 196 0.026
negative regulation of protein metabolic process GO:0051248 391 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
regeneration GO:0031099 4 0.025
gtp metabolic process GO:0046039 239 0.025
regulation of nucleotide metabolic process GO:0006140 269 0.025
positive regulation of nucleoside metabolic process GO:0045979 186 0.025
hindbrain development GO:0030902 3 0.025
circadian behavior GO:0048512 2 0.024
peptidyl tyrosine modification GO:0018212 170 0.024
apoptotic signaling pathway GO:0097190 268 0.024
Mouse
cellular ion homeostasis GO:0006873 168 0.024
regulation of metal ion transport GO:0010959 120 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
cation homeostasis GO:0055080 189 0.024
regulation of nucleotide catabolic process GO:0030811 205 0.024
negative regulation of cellular component organization GO:0051129 235 0.023
av node cell to bundle of his cell communication GO:0086067 4 0.023
Human
regulation of locomotion GO:0040012 329 0.023
defense response GO:0006952 315 0.023
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.023
regulation of kinase activity GO:0043549 314 0.023
intracellular protein transport GO:0006886 270 0.023
cellular response to oxygen containing compound GO:1901701 276 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
organic anion transport GO:0015711 103 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
divalent metal ion transport GO:0070838 152 0.023
limbic system development GO:0021761 3 0.023
calcium ion transport GO:0006816 147 0.023
cellular macromolecule catabolic process GO:0044265 380 0.022
positive regulation of catabolic process GO:0009896 310 0.022
negative regulation of neurological system process GO:0031645 2 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
regulation of transferase activity GO:0051338 355 0.022
regulation of protein localization GO:0032880 296 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
cellular response to organonitrogen compound GO:0071417 124 0.022
regulation of gtp catabolic process GO:0033124 180 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.022
chloride transport GO:0006821 41 0.022
cellular response to ammonium ion GO:0071242 4 0.022
dephosphorylation GO:0016311 209 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.021
cell part morphogenesis GO:0032990 137 0.021
positive regulation of secretion GO:0051047 116 0.021
regulation of gtpase activity GO:0043087 180 0.021
positive regulation of gtpase activity GO:0043547 166 0.021
sensory perception GO:0007600 103 0.021
long term memory GO:0007616 2 0.021
divalent inorganic cation homeostasis GO:0072507 136 0.021
carbohydrate metabolic process GO:0005975 207 0.021
cell cell signaling GO:0007267 155 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
regulation of cardiac muscle contraction GO:0055117 33 0.021
Human
neuron projection regeneration GO:0031102 1 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
mitotic cell cycle process GO:1903047 286 0.021
sodium ion transmembrane transport GO:0035725 59 0.020
Human Mouse Rat
cellular response to organic cyclic compound GO:0071407 127 0.020
actin cytoskeleton organization GO:0030036 207 0.020
regulation of cell migration GO:0030334 289 0.020
segmentation GO:0035282 4 0.020
motor neuron axon guidance GO:0008045 2 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
anion transmembrane transport GO:0098656 76 0.020
regulation of protein kinase activity GO:0045859 289 0.020
regulation of multi organism process GO:0043900 157 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
mating GO:0007618 1 0.020
neuron projection development GO:0031175 106 0.020
calcium ion homeostasis GO:0055074 122 0.020
inorganic anion transmembrane transport GO:0098661 47 0.020
metencephalon development GO:0022037 2 0.020
neuroblast proliferation GO:0007405 4 0.020
maintenance of location GO:0051235 112 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
regulation of proteolysis GO:0030162 293 0.020
chloride transmembrane transport GO:1902476 38 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
cellular response to growth factor stimulus GO:0071363 197 0.019
regulation of cell cycle GO:0051726 393 0.019
protein catabolic process GO:0030163 325 0.019
neuron development GO:0048666 113 0.019
metal ion homeostasis GO:0055065 169 0.019
regulation of cell adhesion GO:0030155 166 0.019
oocyte differentiation GO:0009994 2 0.019
blastoderm segmentation GO:0007350 2 0.019
nerve development GO:0021675 4 0.019
positive regulation of cell death GO:0010942 263 0.019
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 2 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
immune response GO:0006955 307 0.018
positive regulation of immune system process GO:0002684 283 0.018
protein targeting GO:0006605 187 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
ganglioside biosynthetic process GO:0001574 3 0.018
negative regulation of transport GO:0051051 176 0.018
anterior posterior axis specification GO:0009948 2 0.018
synaptic vesicle endocytosis GO:0048488 2 0.018
neuronal action potential GO:0019228 9 0.018
Rat
regulation of mapk cascade GO:0043408 262 0.018
cell substrate adhesion GO:0031589 132 0.018
cell junction organization GO:0034330 79 0.018
response to external biotic stimulus GO:0043207 261 0.018
exocytosis GO:0006887 71 0.018
response to biotic stimulus GO:0009607 276 0.018
regulation of muscle contraction GO:0006937 45 0.018
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
spermatid differentiation GO:0048515 4 0.017
protein localization to membrane GO:0072657 160 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
positive regulation of ion transport GO:0043270 87 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
cellular response to nitrogen compound GO:1901699 144 0.017
regulation of cell motility GO:2000145 299 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
oocyte development GO:0048599 1 0.017
regulation of neuronal synaptic plasticity GO:0048168 1 0.017
positive regulation of ras gtpase activity GO:0032320 117 0.017
nucleotide biosynthetic process GO:0009165 109 0.017
microtubule based process GO:0007017 210 0.017
camp metabolic process GO:0046058 61 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
stem cell division GO:0017145 2 0.017
negative regulation of cell adhesion GO:0007162 64 0.017
cell projection morphogenesis GO:0048858 129 0.017
regulation of protein transport GO:0051223 213 0.017
response to other organism GO:0051707 261 0.017
tripartite regional subdivision GO:0007351 2 0.017
regulation of cell development GO:0060284 161 0.017
membrane hyperpolarization GO:0060081 1 0.017
sodium ion transport GO:0006814 61 0.017
Human Mouse Rat
cellular protein catabolic process GO:0044257 261 0.017
cellular cation homeostasis GO:0030003 163 0.017
regulation of protein complex assembly GO:0043254 147 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
regulation of cytokine production GO:0001817 232 0.017
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.017
protein oligomerization GO:0051259 173 0.017
negative regulation of synaptic transmission GO:0050805 2 0.017
cgmp catabolic process GO:0046069 3 0.017
sensory perception of smell GO:0007608 2 0.017
taxis GO:0042330 157 0.017
regulation of muscle system process GO:0090257 53 0.016
Human
regulation of protein catabolic process GO:0042176 155 0.016
response to axon injury GO:0048678 1 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
cellular divalent inorganic cation homeostasis GO:0072503 128 0.016
response to wounding GO:0009611 168 0.016
positive regulation of transferase activity GO:0051347 227 0.016
endocytosis GO:0006897 159 0.016
lipid biosynthetic process GO:0008610 177 0.016
positive regulation of developmental process GO:0051094 314 0.016
response to growth factor GO:0070848 205 0.016
regulation of intracellular transport GO:0032386 195 0.016
activation of mapk activity by adrenergic receptor signaling pathway GO:0071883 3 0.016
positive regulation of organelle organization GO:0010638 195 0.016
sequestering of metal ion GO:0051238 24 0.016
negative regulation of cell death GO:0060548 345 0.016
cell cell junction organization GO:0045216 69 0.016
visual behavior GO:0007632 2 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
regulation of transmembrane transporter activity GO:0022898 74 0.016
visual learning GO:0008542 1 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
regulation of ras gtpase activity GO:0032318 128 0.016
regulation of ion homeostasis GO:2000021 73 0.016
Human
regulation of establishment of protein localization GO:0070201 242 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
negative regulation of programmed cell death GO:0043069 321 0.016
glycerolipid metabolic process GO:0046486 107 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
protein processing GO:0016485 226 0.016
protein maturation GO:0051604 233 0.015
oxidation reduction process GO:0055114 396 0.015
cellular calcium ion homeostasis GO:0006874 117 0.015
regulation of axon guidance GO:1902667 3 0.015
regulation of ion transmembrane transporter activity GO:0032412 72 0.015
protein ubiquitination GO:0016567 314 0.015
regulation of blood circulation GO:1903522 59 0.015
Human
cellular response to dna damage stimulus GO:0006974 379 0.015
cellular protein complex assembly GO:0043623 188 0.015
somatic stem cell division GO:0048103 1 0.015
regulation of transporter activity GO:0032409 82 0.015
interspecies interaction between organisms GO:0044419 156 0.015
response to lipid GO:0033993 206 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
positive regulation of kinase activity GO:0033674 204 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
growth GO:0040007 202 0.015
response to drug GO:0042493 81 0.015
neuropeptide signaling pathway GO:0007218 19 0.015
spermatid development GO:0007286 4 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
regulation of cell cycle process GO:0010564 266 0.015
actin filament organization GO:0007015 128 0.015
establishment of protein localization to organelle GO:0072594 172 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.014
organelle assembly GO:0070925 176 0.014
cerebellum development GO:0021549 2 0.014
camp biosynthetic process GO:0006171 47 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
cell junction assembly GO:0034329 67 0.014
ribose phosphate biosynthetic process GO:0046390 82 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
cell matrix adhesion GO:0007160 85 0.014
regulation of cell projection organization GO:0031344 107 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
peptidyl serine modification GO:0018209 106 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
negative regulation of protein modification process GO:0031400 200 0.014
sensory perception of chemical stimulus GO:0007606 38 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
response to radiation GO:0009314 151 0.014
protein homooligomerization GO:0051260 100 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 0.014
negative regulation of protein processing GO:0010955 142 0.014
salivary gland morphogenesis GO:0007435 4 0.014
regulation of cell differentiation GO:0045595 393 0.014
positive regulation of axon extension GO:0045773 4 0.014
innate immune response GO:0045087 178 0.014
ribonucleotide biosynthetic process GO:0009260 81 0.014
epithelium development GO:0060429 227 0.014
potassium ion import GO:0010107 9 0.014
peptide transport GO:0015833 74 0.014
phospholipid metabolic process GO:0006644 99 0.014
sequestering of calcium ion GO:0051208 17 0.014
regulation of protein maturation GO:1903317 150 0.014
response to cocaine GO:0042220 1 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.014
multicellular organismal response to stress GO:0033555 1 0.014
negative regulation of cell cycle GO:0045786 193 0.014
regulation of behavior GO:0050795 82 0.014
synaptic vesicle recycling GO:0036465 3 0.013
regulation of cell growth GO:0001558 135 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
regulation of cellular response to stress GO:0080135 244 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
compound eye development GO:0048749 1 0.013
cell division GO:0051301 168 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.013
glial cell migration GO:0008347 4 0.013
heart contraction GO:0060047 62 0.013
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
negative regulation of proteolysis GO:0045861 132 0.013
long term synaptic potentiation GO:0060291 1 0.013
regulation of neurogenesis GO:0050767 82 0.013
cell growth GO:0016049 160 0.013
regulation of heart contraction GO:0008016 50 0.013
Human
purine containing compound biosynthetic process GO:0072522 88 0.013
cytokine production GO:0001816 247 0.013
positive regulation of protein transport GO:0051222 135 0.013
endosomal transport GO:0016197 129 0.013
sensory perception of pain GO:0019233 4 0.013
chromatin modification GO:0016568 298 0.013
calcium ion transmembrane transport GO:0070588 76 0.013
response to cytokine GO:0034097 232 0.013
wound healing GO:0042060 115 0.013
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 2 0.013
cell projection assembly GO:0030031 126 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
central nervous system development GO:0007417 123 0.013
plasma membrane organization GO:0007009 115 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
chromatin organization GO:0006325 351 0.013
positive regulation of response to external stimulus GO:0032103 88 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
glycosphingolipid biosynthetic process GO:0006688 3 0.013
asymmetric neuroblast division GO:0055059 1 0.013
regulation of response to wounding GO:1903034 101 0.013
chemotaxis GO:0006935 157 0.013
asymmetric stem cell division GO:0098722 1 0.013
positive regulation of cell development GO:0010720 92 0.013
regulation of epithelial cell proliferation GO:0050678 113 0.013
organic acid biosynthetic process GO:0016053 97 0.013
single organismal cell cell adhesion GO:0016337 148 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
cytosolic calcium ion homeostasis GO:0051480 89 0.012
heart process GO:0003015 62 0.012
Human
circulatory system development GO:0072359 262 0.012
axon regeneration GO:0031103 1 0.012
regulation of exocytosis GO:0017157 46 0.012
regulation of protein processing GO:0070613 150 0.012
inorganic anion transport GO:0015698 60 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
adenylate cyclase inhibiting adrenergic receptor signaling pathway GO:0071881 1 0.012
regulation of heart rate GO:0002027 38 0.012
Human
response to inorganic substance GO:0010035 127 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
cardiac muscle cell action potential GO:0086001 23 0.012
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.012
cardiovascular system development GO:0072358 262 0.012
organelle localization GO:0051640 84 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
protein autophosphorylation GO:0046777 123 0.012
dna repair GO:0006281 198 0.012
negative regulation of protein maturation GO:1903318 142 0.012
amide transport GO:0042886 76 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
purine ribonucleotide biosynthetic process GO:0009152 79 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
cardiac conduction GO:0061337 23 0.012
Human
negative regulation of phosphorylation GO:0042326 174 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.012
regulation of cell substrate adhesion GO:0010810 68 0.012
hippocampus development GO:0021766 1 0.012
small molecule catabolic process GO:0044282 92 0.012
positive regulation of cytoskeleton organization GO:0051495 83 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
glycoprotein metabolic process GO:0009100 110 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
histone modification GO:0016570 251 0.012
cell activation GO:0001775 213 0.012
negative regulation of secretion GO:0051048 58 0.012

SCN2A disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.049
nervous system disease DOID:863 431 0.049
disease of metabolism DOID:0014667 295 0.029
Human
sensory system disease DOID:0050155 203 0.021
disease of cellular proliferation DOID:14566 174 0.021
epilepsy syndrome DOID:1826 41 0.021
brain disease DOID:936 73 0.021
eye and adnexa disease DOID:1492 150 0.020
inherited metabolic disorder DOID:655 242 0.019
Human
cancer DOID:162 167 0.018
organ system cancer DOID:0050686 164 0.018
retinal disease DOID:5679 118 0.017
eye disease DOID:5614 149 0.017
neurodegenerative disease DOID:1289 102 0.015
musculoskeletal system disease DOID:17 223 0.014
Human
disease of mental health DOID:150 70 0.014
connective tissue disease DOID:65 109 0.014