Homo sapiens

61 known processes

EPRS

glutamyl-prolyl-tRNA synthetase

(Aliases: DKFZp313B047,GLUPRORS,QPRS,PARS,QARS,EARS)

EPRS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
trna aminoacylation for protein translation GO:0006418 8 1.000
amino acid activation GO:0043038 12 1.000
trna aminoacylation GO:0043039 12 1.000
cellular amino acid metabolic process GO:0006520 116 0.996
trna metabolic process GO:0006399 35 0.995
protein folding GO:0006457 38 0.982
translation GO:0006412 132 0.972
ncrna metabolic process GO:0034660 108 0.888
post embryonic development GO:0009791 2 0.632
Worm
negative regulation of apoptotic process GO:0043066 316 0.580
negative regulation of cell death GO:0060548 345 0.513
regulation of translation GO:0006417 89 0.445
transmembrane transport GO:0055085 399 0.376
response to organonitrogen compound GO:0010243 156 0.297
vesicle mediated transport GO:0016192 371 0.267
mitochondrial rna metabolic process GO:0000959 15 0.235
establishment of protein localization to organelle GO:0072594 172 0.222
mapk cascade GO:0000165 288 0.217
aging GO:0007568 66 0.202
cellular response to endogenous stimulus GO:0071495 336 0.188
receptor mediated endocytosis GO:0006898 84 0.157
multicellular organismal aging GO:0010259 3 0.139
mitochondrion organization GO:0007005 156 0.136
ossification GO:0001503 121 0.134
signal transduction in response to dna damage GO:0042770 57 0.130
circadian sleep wake cycle GO:0042745 2 0.129
regulation of cell cycle GO:0051726 393 0.127
signal transduction by phosphorylation GO:0023014 297 0.118
negative regulation of programmed cell death GO:0043069 321 0.111
regulation of nucleocytoplasmic transport GO:0046822 98 0.106
cellular response to dna damage stimulus GO:0006974 379 0.101
protein localization to organelle GO:0033365 280 0.099
regeneration GO:0031099 4 0.094
intracellular protein transport GO:0006886 270 0.093
embryo development GO:0009790 123 0.093
Worm
rna transport GO:0050658 39 0.091
endomembrane system organization GO:0010256 196 0.091
determination of adult lifespan GO:0008340 2 0.086
cellular protein catabolic process GO:0044257 261 0.077
regulation of dephosphorylation GO:0035303 96 0.075
endocytosis GO:0006897 159 0.073
reproduction GO:0000003 63 0.073
response to abiotic stimulus GO:0009628 336 0.072
response to nitrogen compound GO:1901698 184 0.070
positive regulation of cell cycle GO:0045787 140 0.070
negative regulation of phosphate metabolic process GO:0045936 267 0.067
positive regulation of hydrolase activity GO:0051345 331 0.065
regulation of protein transport GO:0051223 213 0.062
regulation of establishment of protein localization GO:0070201 242 0.062
nucleocytoplasmic transport GO:0006913 176 0.060
lung epithelial cell differentiation GO:0060487 1 0.059
protein catabolic process GO:0030163 325 0.058
cytoplasmic transport GO:0016482 379 0.058
apoptotic signaling pathway GO:0097190 268 0.058
locomotory behavior GO:0007626 1 0.055
response to hormone GO:0009725 175 0.053
negative regulation of epithelial cell proliferation GO:0050680 48 0.052
positive regulation of cellular catabolic process GO:0031331 284 0.052
osteoblast differentiation GO:0001649 92 0.049
response to oxygen containing compound GO:1901700 369 0.047
response to organic cyclic compound GO:0014070 204 0.046
activation of jnkk activity GO:0007256 1 0.046
action potential GO:0001508 34 0.045
regulation of apoptotic signaling pathway GO:2001233 175 0.045
hair cycle GO:0042633 28 0.043
negative regulation of phosphorus metabolic process GO:0010563 267 0.042
regulation of epithelial cell proliferation GO:0050678 113 0.042
alpha amino acid biosynthetic process GO:1901607 23 0.041
nuclear export GO:0051168 69 0.041
protein import GO:0017038 130 0.040
cellular response to cytokine stimulus GO:0071345 181 0.039
immune response GO:0006955 307 0.039
protein localization to nucleus GO:0034504 136 0.038
nucleus localization GO:0051647 1 0.038
enzyme linked receptor protein signaling pathway GO:0007167 303 0.038
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.037
embryo development ending in birth or egg hatching GO:0009792 34 0.037
Worm
innate immune response GO:0045087 178 0.037
apoptotic mitochondrial changes GO:0008637 57 0.037
regulation of intracellular transport GO:0032386 195 0.036
protein autophosphorylation GO:0046777 123 0.035
regulation of mitotic cell cycle GO:0007346 189 0.035
cellular component morphogenesis GO:0032989 314 0.035
positive regulation of cellular component organization GO:0051130 376 0.035
negative regulation of protein metabolic process GO:0051248 391 0.034
intrinsic apoptotic signaling pathway GO:0097193 127 0.034
positive regulation of developmental process GO:0051094 314 0.034
immune system development GO:0002520 195 0.033
urogenital system development GO:0001655 65 0.033
angiogenesis GO:0001525 147 0.032
cellular macromolecule catabolic process GO:0044265 380 0.031
defense response GO:0006952 315 0.031
single organism nuclear import GO:1902593 104 0.030
positive regulation of mitotic cell cycle GO:0045931 60 0.030
establishment of protein localization to mitochondrion GO:0072655 22 0.030
actin filament based process GO:0030029 224 0.030
cellular protein complex assembly GO:0043623 188 0.030
cell cell signaling GO:0007267 155 0.029
mrna transport GO:0051028 30 0.029
nuclear transport GO:0051169 179 0.029
reactive oxygen species metabolic process GO:0072593 75 0.029
secretion GO:0046903 254 0.028
response to amino acid GO:0043200 14 0.028
response to radiation GO:0009314 151 0.028
response to endoplasmic reticulum stress GO:0034976 49 0.028
negative regulation of protein phosphorylation GO:0001933 140 0.027
protein targeting GO:0006605 187 0.027
regulation of cellular response to stress GO:0080135 244 0.027
renal system development GO:0072001 63 0.026
regulation of autophagy GO:0010506 52 0.025
regulation of endothelial cell proliferation GO:0001936 56 0.025
proteasomal protein catabolic process GO:0010498 176 0.025
response to light stimulus GO:0009416 87 0.024
ubiquitin dependent protein catabolic process GO:0006511 206 0.024
single organism cellular localization GO:1902580 332 0.024
alpha amino acid metabolic process GO:1901605 72 0.024
regulation of protein localization GO:0032880 296 0.024
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.024
one carbon metabolic process GO:0006730 1 0.024
cellular response to hormone stimulus GO:0032870 125 0.023
circadian behavior GO:0048512 2 0.023
positive regulation of cell division GO:0051781 59 0.023
positive regulation of apoptotic signaling pathway GO:2001235 70 0.023
response to mechanical stimulus GO:0009612 51 0.023
tripartite regional subdivision GO:0007351 2 0.023
photoreceptor cell differentiation GO:0046530 2 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.023
positive regulation of immune system process GO:0002684 283 0.022
sperm egg recognition GO:0035036 3 0.022
response to lipid GO:0033993 206 0.022
meiosis i GO:0007127 4 0.021
response to wounding GO:0009611 168 0.021
regulation of protein complex assembly GO:0043254 147 0.021
protein maturation GO:0051604 233 0.021
negative regulation of protein catabolic process GO:0042177 59 0.021
wound healing GO:0042060 115 0.020
response to virus GO:0009615 126 0.020
rna export from nucleus GO:0006405 33 0.020
organelle assembly GO:0070925 176 0.020
positive regulation of transport GO:0051050 336 0.020
peptidyl serine modification GO:0018209 106 0.020
protein import into mitochondrial matrix GO:0030150 1 0.020
dephosphorylation GO:0016311 209 0.020
protein import into nucleus GO:0006606 104 0.020
cellular amide metabolic process GO:0043603 69 0.020
positive regulation of catabolic process GO:0009896 310 0.020
nervous system development GO:0007399 293 0.019
neuromuscular junction development GO:0007528 3 0.019
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.019
regulation of phosphatase activity GO:0010921 81 0.019
positive regulation of dna metabolic process GO:0051054 73 0.019
protein targeting to nucleus GO:0044744 104 0.019
aspartate family amino acid biosynthetic process GO:0009067 6 0.019
response to peptide hormone GO:0043434 61 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
nucleobase containing compound transport GO:0015931 51 0.019
pigment biosynthetic process GO:0046148 10 0.019
regulation of protein targeting GO:1903533 91 0.018
cell morphogenesis GO:0000902 296 0.018
rna localization GO:0006403 41 0.018
lipid localization GO:0010876 106 0.018
regulation of protein import into nucleus GO:0042306 78 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
myosin filament assembly GO:0031034 2 0.018
cellular response to nitrogen compound GO:1901699 144 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
hemopoiesis GO:0030097 180 0.018
response to cytokine GO:0034097 232 0.018
negative regulation of dephosphorylation GO:0035305 63 0.018
myeloid cell differentiation GO:0030099 117 0.017
regulation of protein kinase activity GO:0045859 289 0.017
rna processing GO:0006396 255 0.017
regulation of cell cycle process GO:0010564 266 0.017
myosin filament organization GO:0031033 2 0.017
ribosomal small subunit biogenesis GO:0042274 13 0.017
positive regulation of peptidase activity GO:0010952 88 0.017
neural tube formation GO:0001841 3 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
striated muscle myosin thick filament assembly GO:0071688 2 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
positive regulation of cell proliferation GO:0008284 301 0.016
response to other organism GO:0051707 261 0.016
ribonucleoprotein complex localization GO:0071166 4 0.016
system process GO:0003008 349 0.016
regulation of cell differentiation GO:0045595 393 0.016
positive regulation of cell development GO:0010720 92 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
lens development in camera type eye GO:0002088 2 0.016
gland development GO:0048732 48 0.016
regulation of body fluid levels GO:0050878 99 0.016
microtubule cytoskeleton organization GO:0000226 176 0.015
response to growth factor GO:0070848 205 0.015
eye development GO:0001654 42 0.015
kidney development GO:0001822 53 0.015
regulation of neuron death GO:1901214 56 0.015
nitrogen compound transport GO:0071705 191 0.015
leukocyte migration GO:0050900 107 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
spermatid differentiation GO:0048515 4 0.015
endoplasmic reticulum organization GO:0007029 20 0.015
cytoplasmic translational initiation GO:0002183 6 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
positive regulation of innate immune response GO:0045089 79 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
establishment of rna localization GO:0051236 39 0.014
positive regulation of cytokine production GO:0001819 167 0.014
regulation of protein localization to nucleus GO:1900180 85 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
rna 3 end processing GO:0031123 35 0.014
cell cycle checkpoint GO:0000075 117 0.014
negative regulation of neuron differentiation GO:0045665 21 0.014
adult locomotory behavior GO:0008344 1 0.014
protein localization to mitochondrion GO:0070585 25 0.014
regulation of dna metabolic process GO:0051052 153 0.014
mitotic cell cycle GO:0000278 326 0.014
detection of stimulus GO:0051606 85 0.014
response to unfolded protein GO:0006986 24 0.014
response to topologically incorrect protein GO:0035966 29 0.014
cellular amino acid catabolic process GO:0009063 31 0.014
response to biotic stimulus GO:0009607 276 0.013
protein transmembrane transport GO:0071806 25 0.013
rhythmic behavior GO:0007622 2 0.013
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.013
compound eye development GO:0048749 1 0.013
rna 5 end processing GO:0000966 2 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
vasculature development GO:0001944 181 0.013
single organism membrane organization GO:0044802 268 0.013
regulation of antimicrobial humoral response GO:0002759 1 0.013
regulation of microtubule based process GO:0032886 74 0.013
negative regulation of intracellular transport GO:0032387 60 0.013
endothelial cell proliferation GO:0001935 65 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
response to extracellular stimulus GO:0009991 85 0.013
regulation of transferase activity GO:0051338 355 0.013
positive regulation of defense response GO:0031349 87 0.012
amine metabolic process GO:0009308 44 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
negative regulation of cytoplasmic transport GO:1903650 46 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
negative regulation of protein modification process GO:0031400 200 0.012
mrna export from nucleus GO:0006406 29 0.012
cell growth GO:0016049 160 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
positive regulation of protein transport GO:0051222 135 0.012
lung cell differentiation GO:0060479 1 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
regulation of cortisol secretion GO:0051462 4 0.012
negative regulation of protein processing GO:0010955 142 0.011
negative regulation of developmental process GO:0051093 247 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.011
neurological system process GO:0050877 163 0.011
lactation GO:0007595 3 0.011
eye pigmentation GO:0048069 1 0.011
secretion by cell GO:0032940 226 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of defense response GO:0031347 154 0.011
protein deubiquitination GO:0016579 79 0.011
spindle assembly GO:0051225 29 0.011
ncrna processing GO:0034470 83 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.010
regulation of translational initiation GO:0006446 24 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010
regulation of membrane potential GO:0042391 95 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
nucleoside phosphate biosynthetic process GO:1901293 109 0.010
endoplasmic reticulum unfolded protein response GO:0030968 16 0.010
regulation of protein catabolic process GO:0042176 155 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
fertilization GO:0009566 12 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010

EPRS disease predictions

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 38 0.276
nervous system disease DOID:863 431 0.276
neuropathy DOID:870 52 0.276
central nervous system disease DOID:331 186 0.210
charcot marie tooth disease DOID:10595 33 0.010