Homo sapiens

74 known processes

FEM1B

fem-1 homolog b (C. elegans)

(Aliases: F1A-ALPHA,DKFZp451E0710,FIAA)

FEM1B biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular amine metabolic process GO:0033239 3 0.791
cellular ketone metabolic process GO:0042180 80 0.682
cellular amine metabolic process GO:0044106 41 0.570
amine metabolic process GO:0009308 44 0.552
regulation of cellular ketone metabolic process GO:0010565 50 0.515
regulation of cellular amine metabolic process GO:0033238 11 0.489
regulation of cellular amino acid metabolic process GO:0006521 6 0.486
cellular amino acid metabolic process GO:0006520 116 0.443
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.423
positive regulation of cellular component movement GO:0051272 181 0.332
covalent chromatin modification GO:0016569 254 0.269
positive regulation of cell motility GO:2000147 177 0.262
protein dephosphorylation GO:0006470 81 0.226
histone modification GO:0016570 251 0.226
negative regulation of phosphorus metabolic process GO:0010563 267 0.200
regulation of kinase activity GO:0043549 314 0.198
regulation of transferase activity GO:0051338 355 0.196
peptidyl threonine dephosphorylation GO:0035970 7 0.191
regulation of cell migration GO:0030334 289 0.189
positive regulation of locomotion GO:0040017 186 0.188
post embryonic development GO:0009791 2 0.166
modification dependent macromolecule catabolic process GO:0043632 212 0.163
negative regulation of protein kinase activity GO:0006469 98 0.152
regulation of locomotion GO:0040012 329 0.150
positive regulation of cell migration GO:0030335 172 0.147
positive regulation of proteolysis GO:0045862 142 0.146
protein ubiquitination GO:0016567 314 0.144
peptidyl serine phosphorylation GO:0018105 101 0.136
behavior GO:0007610 112 0.135
dephosphorylation GO:0016311 209 0.135
regulation of proteolysis GO:0030162 293 0.129
regulation of growth GO:0040008 165 0.129
negative regulation of catalytic activity GO:0043086 335 0.124
protein catabolic process GO:0030163 325 0.117
negative regulation of phosphate metabolic process GO:0045936 267 0.115
regulation of cell motility GO:2000145 299 0.113
regulation of cellular component biogenesis GO:0044087 281 0.112
peptidyl serine modification GO:0018209 106 0.111
memory GO:0007613 3 0.107
carbohydrate metabolic process GO:0005975 207 0.107
negative regulation of phosphorylation GO:0042326 174 0.102
regulation of protein kinase activity GO:0045859 289 0.102
positive regulation of hydrolase activity GO:0051345 331 0.100
negative regulation of protein modification process GO:0031400 200 0.092
negative regulation of cellular protein metabolic process GO:0032269 353 0.091
positive regulation of apoptotic process GO:0043065 246 0.089
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.088
negative regulation of kinase activity GO:0033673 106 0.088
intrinsic apoptotic signaling pathway GO:0097193 127 0.088
negative regulation of transferase activity GO:0051348 124 0.086
actin cytoskeleton organization GO:0030036 207 0.085
regulation of response to external stimulus GO:0032101 222 0.085
Human
biological adhesion GO:0022610 331 0.081
positive regulation of programmed cell death GO:0043068 249 0.081
actin filament bundle assembly GO:0051017 54 0.079
regulation of chemotaxis GO:0050920 74 0.078
negative regulation of protein phosphorylation GO:0001933 140 0.075
positive regulation of cell death GO:0010942 263 0.074
cellular protein catabolic process GO:0044257 261 0.074
regulation of proteasomal protein catabolic process GO:0061136 87 0.074
ameboidal type cell migration GO:0001667 135 0.073
chromatin organization GO:0006325 351 0.073
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.072
regulation of cellular component movement GO:0051270 334 0.071
cytoplasmic transport GO:0016482 379 0.068
regulation of peptidase activity GO:0052547 180 0.066
cellular macromolecule catabolic process GO:0044265 380 0.066
negative regulation of protein metabolic process GO:0051248 391 0.065
adherens junction organization GO:0034332 36 0.064
regulation of cytoskeleton organization GO:0051493 177 0.063
small gtpase mediated signal transduction GO:0007264 78 0.061
modification dependent protein catabolic process GO:0019941 209 0.060
chemotaxis GO:0006935 157 0.059
positive regulation of actin filament bundle assembly GO:0032233 25 0.059
proteasomal protein catabolic process GO:0010498 176 0.059
long term memory GO:0007616 2 0.059
apoptotic signaling pathway GO:0097190 268 0.059
positive regulation of cellular component organization GO:0051130 376 0.058
tissue migration GO:0090130 119 0.058
positive regulation of cytoskeleton organization GO:0051495 83 0.056
mitotic cell cycle GO:0000278 326 0.055
positive regulation of cell substrate adhesion GO:0010811 37 0.055
actin filament bundle organization GO:0061572 54 0.055
regulation of protein catabolic process GO:0042176 155 0.053
stress fiber assembly GO:0043149 40 0.053
female gamete generation GO:0007292 2 0.050
growth GO:0040007 202 0.050
positive regulation of epithelial cell migration GO:0010634 55 0.049
single organism carbohydrate metabolic process GO:0044723 193 0.047
actin filament organization GO:0007015 128 0.047
maintenance of protein location in cell GO:0032507 56 0.046
actomyosin structure organization GO:0031032 59 0.045
positive regulation of adherens junction organization GO:1903393 12 0.045
ubiquitin dependent protein catabolic process GO:0006511 206 0.045
regulation of actin filament based process GO:0032970 141 0.044
system process GO:0003008 349 0.044
positive regulation of organelle organization GO:0010638 195 0.044
negative regulation of cell proliferation GO:0008285 228 0.044
regulation of peptidyl serine phosphorylation GO:0033135 50 0.044
positive regulation of response to external stimulus GO:0032103 88 0.043
epithelial cell migration GO:0010631 119 0.043
positive regulation of chemotaxis GO:0050921 57 0.043
positive regulation of behavior GO:0048520 60 0.042
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.042
actin filament based process GO:0030029 224 0.041
chromosome segregation GO:0007059 114 0.041
positive regulation of peptidase activity GO:0010952 88 0.041
response to oxygen containing compound GO:1901700 369 0.041
mitotic cell cycle process GO:1903047 286 0.040
mitotic nuclear division GO:0007067 119 0.040
epithelium migration GO:0090132 119 0.039
regulation of cell adhesion GO:0030155 166 0.039
behavioral response to ethanol GO:0048149 2 0.038
determination of adult lifespan GO:0008340 2 0.038
regulation of cell cycle GO:0051726 393 0.037
chemical homeostasis GO:0048878 306 0.037
positive regulation of cell adhesion GO:0045785 84 0.036
peptidyl tyrosine phosphorylation GO:0018108 170 0.036
single organism cellular localization GO:1902580 332 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
chromatin modification GO:0016568 298 0.035
regulation of cell substrate adhesion GO:0010810 68 0.035
anterior posterior axis specification GO:0009948 2 0.035
regulation of epithelial cell migration GO:0010632 93 0.035
cell cell junction organization GO:0045216 69 0.034
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.034
cell adhesion GO:0007155 325 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.033
defense response GO:0006952 315 0.033
Human
oogenesis GO:0048477 2 0.033
cell junction organization GO:0034330 79 0.033
cellular component morphogenesis GO:0032989 314 0.033
protein localization to organelle GO:0033365 280 0.033
positive regulation of catabolic process GO:0009896 310 0.033
peptidyl tyrosine modification GO:0018212 170 0.032
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
regulation of cysteine type endopeptidase activity GO:2000116 127 0.031
meiotic chromosome segregation GO:0045132 4 0.031
neural tube formation GO:0001841 3 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
positive regulation of cell matrix adhesion GO:0001954 23 0.030
positive regulation of stress fiber assembly GO:0051496 22 0.029
golgi vesicle transport GO:0048193 80 0.029
regulation of cellular protein catabolic process GO:1903362 96 0.029
multicellular organismal aging GO:0010259 3 0.028
protein modification by small protein conjugation GO:0032446 342 0.028
cell matrix adhesion GO:0007160 85 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.027
tripartite regional subdivision GO:0007351 2 0.027
oocyte development GO:0048599 1 0.027
nucleoside catabolic process GO:0009164 408 0.026
taxis GO:0042330 157 0.026
positive regulation of endopeptidase activity GO:0010950 84 0.026
response to abiotic stimulus GO:0009628 336 0.026
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 5 0.025
regulation of endopeptidase activity GO:0052548 170 0.025
microtubule based process GO:0007017 210 0.025
regulation of behavior GO:0050795 82 0.025
segmentation GO:0035282 4 0.025
regulation of nucleotide metabolic process GO:0006140 269 0.025
somitogenesis GO:0001756 2 0.024
positive regulation of meiotic cell cycle GO:0051446 2 0.024
posttranscriptional regulation of gene expression GO:0010608 213 0.024
cellular homeostasis GO:0019725 196 0.024
regulation of actin cytoskeleton organization GO:0032956 116 0.024
positive regulation of cellular component biogenesis GO:0044089 158 0.023
negative regulation of jak stat cascade GO:0046426 4 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.023
regulation of cell junction assembly GO:1901888 29 0.023
cell growth GO:0016049 160 0.023
cell substrate adhesion GO:0031589 132 0.023
cell activation GO:0001775 213 0.023
cell junction assembly GO:0034329 67 0.023
blastoderm segmentation GO:0007350 2 0.022
lipid metabolic process GO:0006629 381 0.022
glucose metabolic process GO:0006006 45 0.022
positive regulation of focal adhesion assembly GO:0051894 11 0.022
cell substrate adherens junction assembly GO:0007045 30 0.022
maintenance of location GO:0051235 112 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
maintenance of protein location GO:0045185 57 0.022
embryonic epithelial tube formation GO:0001838 4 0.022
neuromuscular junction development GO:0007528 3 0.022
cell fate determination GO:0001709 3 0.022
regulation of meiotic cell cycle GO:0051445 4 0.022
sister chromatid segregation GO:0000819 54 0.022
monosaccharide metabolic process GO:0005996 74 0.021
positive regulation of growth GO:0045927 58 0.021
neurogenesis GO:0022008 169 0.021
neurotransmitter secretion GO:0007269 4 0.021
ras protein signal transduction GO:0007265 73 0.021
glycosyl compound catabolic process GO:1901658 413 0.020
regulation of cell matrix adhesion GO:0001952 42 0.020
regulation of protein ubiquitination GO:0031396 95 0.020
regulation of tor signaling GO:0032006 30 0.020
adherens junction assembly GO:0034333 34 0.020
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.020
negative regulation of cell growth GO:0030308 83 0.019
oocyte differentiation GO:0009994 2 0.019
immune response GO:0006955 307 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
cell morphogenesis GO:0000902 296 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
mitotic sister chromatid segregation GO:0000070 53 0.019
rho protein signal transduction GO:0007266 26 0.019
positive regulation of immune system process GO:0002684 283 0.018
cell cell signaling GO:0007267 155 0.018
transmembrane transport GO:0055085 399 0.018
hexose metabolic process GO:0019318 55 0.018
endomembrane system organization GO:0010256 196 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.018
positive regulation of kinase activity GO:0033674 204 0.018
cellular response to endogenous stimulus GO:0071495 336 0.018
protein processing GO:0016485 226 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
gtp metabolic process GO:0046039 239 0.017
maintenance of location in cell GO:0051651 62 0.017
regulation of cell differentiation GO:0045595 393 0.017
stem cell division GO:0017145 2 0.016
neurological system process GO:0050877 163 0.016
locomotory behavior GO:0007626 1 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
peptide transport GO:0015833 74 0.016
protein stabilization GO:0050821 64 0.016
regulation of secretion by cell GO:1903530 177 0.016
response to nitrogen compound GO:1901698 184 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.016
response to organic cyclic compound GO:0014070 204 0.016
inner ear morphogenesis GO:0042472 4 0.016
neural tube closure GO:0001843 3 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
positive regulation of developmental process GO:0051094 314 0.015
regulation of stress fiber assembly GO:0051492 32 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
response to organonitrogen compound GO:0010243 156 0.015
amide transport GO:0042886 76 0.015
cell cycle phase transition GO:0044770 173 0.015
cellular chemical homeostasis GO:0055082 180 0.015
hormone transport GO:0009914 68 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
positive regulation of phosphorylation GO:0042327 394 0.014
regulation of erbb signaling pathway GO:1901184 27 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
regulation of protein maturation GO:1903317 150 0.014
regulation of protein processing GO:0070613 150 0.014
regulation of peptide hormone secretion GO:0090276 41 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
immune system development GO:0002520 195 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
regulation of microtubule cytoskeleton organization GO:0070507 61 0.014
regulation of cell activation GO:0050865 125 0.014
regulation of focal adhesion assembly GO:0051893 20 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
ribonucleotide catabolic process GO:0009261 405 0.014
negative regulation of cell cycle GO:0045786 193 0.014
regulation of leukocyte activation GO:0002694 115 0.014
erbb signaling pathway GO:0038127 44 0.014
organophosphate catabolic process GO:0046434 430 0.014
positive regulation of protein catabolic process GO:0045732 75 0.013
protein maturation GO:0051604 233 0.013
negative regulation of immune system process GO:0002683 136 0.013
small molecule biosynthetic process GO:0044283 157 0.013
regulation of cell cycle process GO:0010564 266 0.013
cytokine production GO:0001816 247 0.013
regulation of mitosis GO:0007088 63 0.013
mapk cascade GO:0000165 288 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
neuron development GO:0048666 113 0.013
nervous system development GO:0007399 293 0.013
positive regulation of transferase activity GO:0051347 227 0.013
mitotic sister chromatid separation GO:0051306 18 0.013
tube closure GO:0060606 3 0.013
response to lipid GO:0033993 206 0.013
response to cytokine GO:0034097 232 0.013
response to alcohol GO:0097305 64 0.012
response to peptide hormone GO:0043434 61 0.012
regulation of protein stability GO:0031647 87 0.012
regulation of carbohydrate metabolic process GO:0006109 54 0.012
negative regulation of alpha beta t cell activation GO:0046636 3 0.012
cellular response to drug GO:0035690 27 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
primary neural tube formation GO:0014020 3 0.012
protein localization to membrane GO:0072657 160 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of nuclear division GO:0051783 65 0.012
wnt signaling pathway GO:0016055 156 0.012
protein oligomerization GO:0051259 173 0.012
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 11 0.012
nitrogen compound transport GO:0071705 191 0.012
positive regulation of cell junction assembly GO:1901890 11 0.012
response to tumor necrosis factor GO:0034612 76 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
signal release GO:0023061 70 0.012
regulation of jak stat cascade GO:0046425 44 0.012
cell substrate junction assembly GO:0007044 35 0.012
single organism reproductive process GO:0044702 98 0.012
Mouse
cytokinesis GO:0000910 96 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
response to drug GO:0042493 81 0.012
cell cycle checkpoint GO:0000075 117 0.012
neuroblast proliferation GO:0007405 4 0.012
hair cell differentiation GO:0035315 2 0.011
intracellular protein transport GO:0006886 270 0.011
cellular lipid metabolic process GO:0044255 303 0.011
establishment of planar polarity GO:0001736 3 0.011
regulation of cell growth GO:0001558 135 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
hindbrain development GO:0030902 3 0.011
regulation of chromosome organization GO:0033044 103 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
regulation of membrane potential GO:0042391 95 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
response to steroid hormone GO:0048545 80 0.011
secretion by cell GO:0032940 226 0.011
innate immune response GO:0045087 178 0.011
histone dephosphorylation GO:0016576 3 0.011
regulation of protein localization GO:0032880 296 0.011
regulation of chromosome segregation GO:0051983 44 0.011
lymphocyte activation GO:0046649 133 0.011
regulation of microtubule based process GO:0032886 74 0.011
regulation of secretion GO:0051046 194 0.011
g2 m transition of mitotic cell cycle GO:0000086 41 0.011
response to external biotic stimulus GO:0043207 261 0.011
regulation of growth rate GO:0040009 1 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
nucleotide catabolic process GO:0009166 408 0.011
protein autophosphorylation GO:0046777 123 0.011
peptide hormone secretion GO:0030072 50 0.010
establishment of tissue polarity GO:0007164 3 0.010
regulation of mapk cascade GO:0043408 262 0.010
neuron differentiation GO:0030182 138 0.010
nuclear transport GO:0051169 179 0.010
regulation of immune response GO:0050776 201 0.010
response to hormone GO:0009725 175 0.010
regulation of lymphocyte activation GO:0051249 103 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010
regulation of hormone secretion GO:0046883 57 0.010
signal transduction by phosphorylation GO:0023014 297 0.010
response to inorganic substance GO:0010035 127 0.010
purine nucleotide catabolic process GO:0006195 405 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010

FEM1B disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.029
nervous system disease DOID:863 431 0.029
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.023
neurodegenerative disease DOID:1289 102 0.022
sensory system disease DOID:0050155 203 0.017
gastrointestinal system cancer DOID:3119 52 0.015
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
muscular disease DOID:0080000 114 0.011
musculoskeletal system disease DOID:17 223 0.011