Homo sapiens

22 known processes

EDF1

endothelial differentiation-related factor 1

(Aliases: MGC9058,EDF-1,MBF1)

EDF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cholesterol storage GO:0010887 4 0.410
fatty acid metabolic process GO:0006631 115 0.357
cellular lipid metabolic process GO:0044255 303 0.305
lipid metabolic process GO:0006629 381 0.278
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.272
positive regulation of hydrolase activity GO:0051345 331 0.229
coenzyme metabolic process GO:0006732 65 0.186
regulation of cellular ketone metabolic process GO:0010565 50 0.183
negative regulation of pinocytosis GO:0048550 4 0.165
negative regulation of macrophage activation GO:0043031 1 0.151
positive regulation of transport GO:0051050 336 0.142
innate immune response GO:0045087 178 0.137
negative regulation of secretion by cell GO:1903531 52 0.122
regulation of secretion GO:0051046 194 0.116
monocarboxylic acid metabolic process GO:0032787 185 0.113
negative regulation of multicellular organismal process GO:0051241 317 0.098
positive regulation of toll like receptor signaling pathway GO:0034123 10 0.091
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.090
protein catabolic process GO:0030163 325 0.089
vesicle mediated transport GO:0016192 371 0.082
ribonucleotide catabolic process GO:0009261 405 0.081
negative regulation of response to external stimulus GO:0032102 83 0.079
maintenance of location GO:0051235 112 0.079
membrane organization GO:0061024 292 0.077
cellular response to oxygen containing compound GO:1901701 276 0.076
negative regulation of response to wounding GO:1903035 47 0.075
positive regulation of triglyceride lipase activity GO:0061365 7 0.073
response to lipid GO:0033993 206 0.072
cellular ketone metabolic process GO:0042180 80 0.071
immune response GO:0006955 307 0.069
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.069
cellular protein catabolic process GO:0044257 261 0.067
regulation of defense response GO:0031347 154 0.066
positive regulation of endopeptidase activity GO:0010950 84 0.066
regulation of protein transport GO:0051223 213 0.065
receptor metabolic process GO:0043112 81 0.064
cellular response to lipid GO:0071396 127 0.063
single organism cellular localization GO:1902580 332 0.063
regulation of secretion by cell GO:1903530 177 0.062
regulation of immune response GO:0050776 201 0.060
post embryonic development GO:0009791 2 0.059
modification dependent protein catabolic process GO:0019941 209 0.058
carboxylic acid biosynthetic process GO:0046394 97 0.056
regulation of receptor biosynthetic process GO:0010869 15 0.055
lipid transport GO:0006869 90 0.053
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.053
chemical homeostasis GO:0048878 306 0.053
positive regulation of programmed cell death GO:0043068 249 0.052
positive regulation of immune response GO:0050778 159 0.051
organic hydroxy compound transport GO:0015850 63 0.049
response to oxygen containing compound GO:1901700 369 0.049
regulation of response to external stimulus GO:0032101 222 0.047
positive regulation of immune system process GO:0002684 283 0.047
immune response activating signal transduction GO:0002757 90 0.046
cellular response to endogenous stimulus GO:0071495 336 0.046
positive regulation of proteolysis GO:0045862 142 0.045
lipid localization GO:0010876 106 0.044
negative regulation of protein metabolic process GO:0051248 391 0.044
receptor biosynthetic process GO:0032800 18 0.043
regulation of vesicle mediated transport GO:0060627 130 0.043
regulation of fatty acid metabolic process GO:0019217 24 0.043
modification dependent macromolecule catabolic process GO:0043632 212 0.042
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.042
negative regulation of digestive system process GO:0060457 2 0.042
response to biotic stimulus GO:0009607 276 0.041
ncrna metabolic process GO:0034660 108 0.041
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.041
cellular macromolecule catabolic process GO:0044265 380 0.040
negative regulation of transport GO:0051051 176 0.039
response to external biotic stimulus GO:0043207 261 0.039
enzyme linked receptor protein signaling pathway GO:0007167 303 0.039
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
neuroblast proliferation GO:0007405 4 0.037
cofactor metabolic process GO:0051186 87 0.036
positive regulation of cell death GO:0010942 263 0.036
protein oligomerization GO:0051259 173 0.036
cellular response to hormone stimulus GO:0032870 125 0.035
steroid metabolic process GO:0008202 94 0.035
nucleoside triphosphate catabolic process GO:0009143 394 0.035
response to wounding GO:0009611 168 0.034
regulation of lipid biosynthetic process GO:0046890 47 0.034
positive regulation of toll like receptor 4 signaling pathway GO:0034145 6 0.033
embryo development GO:0009790 123 0.033
cellular response to nitrogen compound GO:1901699 144 0.033
negative regulation of secretion GO:0051048 58 0.032
positive regulation of apoptotic process GO:0043065 246 0.032
female gamete generation GO:0007292 2 0.032
nucleotide catabolic process GO:0009166 408 0.032
activation of immune response GO:0002253 114 0.032
atp catabolic process GO:0006200 157 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.031
regulation of inflammatory response GO:0050727 46 0.031
cell growth GO:0016049 160 0.031
ribonucleoside triphosphate metabolic process GO:0009199 412 0.031
response to cytokine GO:0034097 232 0.031
regeneration GO:0031099 4 0.031
system process GO:0003008 349 0.031
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.030
growth GO:0040007 202 0.030
regulation of endopeptidase activity GO:0052548 170 0.030
defense response GO:0006952 315 0.030
negative regulation of inflammatory response GO:0050728 22 0.029
establishment of protein localization to organelle GO:0072594 172 0.029
purine containing compound catabolic process GO:0072523 411 0.029
negative regulation of immune system process GO:0002683 136 0.028
cellular amine metabolic process GO:0044106 41 0.028
inflammatory response GO:0006954 79 0.028
negative regulation of defense response GO:0031348 47 0.028
regulation of cell growth GO:0001558 135 0.028
regulation of triglyceride metabolic process GO:0090207 11 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.027
ubiquitin dependent protein catabolic process GO:0006511 206 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
organophosphate catabolic process GO:0046434 430 0.027
response to hormone GO:0009725 175 0.027
response to steroid hormone GO:0048545 80 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
response to ketone GO:1901654 19 0.027
regulation of proteolysis GO:0030162 293 0.027
lipid biosynthetic process GO:0008610 177 0.026
mitotic cell cycle process GO:1903047 286 0.026
glycerolipid biosynthetic process GO:0045017 51 0.026
positive regulation of lipoprotein lipase activity GO:0051006 7 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
microtubule cytoskeleton organization GO:0000226 176 0.026
positive regulation of fatty acid metabolic process GO:0045923 11 0.026
positive regulation of lipase activity GO:0060193 28 0.025
mitochondrion organization GO:0007005 156 0.025
pancreatic juice secretion GO:0030157 4 0.025
monocarboxylic acid biosynthetic process GO:0072330 67 0.025
secretion GO:0046903 254 0.025
positive regulation of developmental process GO:0051094 314 0.025
regulation of response to wounding GO:1903034 101 0.025
nucleoside catabolic process GO:0009164 408 0.025
neutral lipid metabolic process GO:0006638 27 0.024
regulation of lipoprotein lipase activity GO:0051004 12 0.024
regulation of lipid metabolic process GO:0019216 96 0.024
negative regulation of cell proliferation GO:0008285 228 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
cellular component morphogenesis GO:0032989 314 0.024
digestion GO:0007586 22 0.024
response to bacterium GO:0009617 144 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
organic acid biosynthetic process GO:0016053 97 0.023
protein localization to membrane GO:0072657 160 0.023
acylglycerol metabolic process GO:0006639 27 0.023
negative regulation of growth GO:0045926 97 0.023
mitotic cell cycle GO:0000278 326 0.022
secretion by cell GO:0032940 226 0.022
apoptotic signaling pathway GO:0097190 268 0.022
protein targeting GO:0006605 187 0.022
response to organic cyclic compound GO:0014070 204 0.022
protein maturation GO:0051604 233 0.022
regulation of endocytosis GO:0030100 72 0.022
cellular response to biotic stimulus GO:0071216 71 0.021
response to peptide GO:1901652 65 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
positive regulation of homeostatic process GO:0032846 47 0.021
response to nitrogen compound GO:1901698 184 0.021
response to organonitrogen compound GO:0010243 156 0.021
purine nucleoside catabolic process GO:0006152 398 0.020
leukocyte activation GO:0045321 164 0.020
protein processing GO:0016485 226 0.020
immune response regulating signaling pathway GO:0002764 97 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.020
glycosyl compound catabolic process GO:1901658 413 0.019
regulation of body fluid levels GO:0050878 99 0.019
sterol homeostasis GO:0055092 28 0.019
single organism reproductive process GO:0044702 98 0.019
cellular response to peptide hormone stimulus GO:0071375 56 0.019
regulation of oxidoreductase activity GO:0051341 43 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
multi organism cellular process GO:0044764 156 0.019
regulation of neurogenesis GO:0050767 82 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
autophagy GO:0006914 88 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
regulation of cell differentiation GO:0045595 393 0.018
cell activation GO:0001775 213 0.018
cholesterol transport GO:0030301 39 0.017
oogenesis GO:0048477 2 0.017
activation of innate immune response GO:0002218 55 0.017
regulation of peptidase activity GO:0052547 180 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
reproductive process GO:0022414 106 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
cellular response to molecule of bacterial origin GO:0071219 62 0.017
regulation of cholesterol homeostasis GO:2000188 2 0.017
intracellular protein transport GO:0006886 270 0.016
cellular amino acid metabolic process GO:0006520 116 0.016
neurogenesis GO:0022008 169 0.016
ncrna processing GO:0034470 83 0.016
cellular response to insulin stimulus GO:0032869 41 0.016
developmental process involved in reproduction GO:0003006 66 0.016
protein localization to organelle GO:0033365 280 0.016
regulation of cell migration GO:0030334 289 0.016
negative regulation of developmental process GO:0051093 247 0.016
positive regulation of defense response GO:0031349 87 0.016
interspecies interaction between organisms GO:0044419 156 0.015
multicellular organismal aging GO:0010259 3 0.015
protein homooligomerization GO:0051260 100 0.015
digestive system process GO:0022600 17 0.015
cell development GO:0048468 328 0.015
regulation of lipid transport GO:0032368 44 0.015
positive regulation of lipid metabolic process GO:0045834 50 0.015
response to peptide hormone GO:0043434 61 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
regulation of system process GO:0044057 101 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
regulation of cell development GO:0060284 161 0.014
actin filament based process GO:0030029 224 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
response to nutrient levels GO:0031667 81 0.014
single organism membrane organization GO:0044802 268 0.014
spindle elongation GO:0051231 4 0.014
endocytosis GO:0006897 159 0.014
positive regulation of peptidase activity GO:0010952 88 0.014
regulation of protein secretion GO:0050708 86 0.014
regulation of cholesterol storage GO:0010885 8 0.014
ras protein signal transduction GO:0007265 73 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
cellular response to acid chemical GO:0071229 44 0.014
cytoplasmic transport GO:0016482 379 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
response to other organism GO:0051707 261 0.013
triglyceride metabolic process GO:0006641 23 0.013
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
response to molecule of bacterial origin GO:0002237 82 0.013
cellular response to lipopolysaccharide GO:0071222 57 0.013
positive regulation of secretion GO:0051047 116 0.013
regulation of hormone levels GO:0010817 125 0.013
small molecule biosynthetic process GO:0044283 157 0.013
response to axon injury GO:0048678 1 0.013
myeloid cell differentiation GO:0030099 117 0.013
microtubule based process GO:0007017 210 0.013
oxidation reduction process GO:0055114 396 0.013
regulation of lipid storage GO:0010883 21 0.013
protein acetylation GO:0006473 116 0.013
regulation of cell motility GO:2000145 299 0.013
reactive oxygen species metabolic process GO:0072593 75 0.012
head development GO:0060322 108 0.012
rna interference GO:0016246 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
hormone metabolic process GO:0042445 61 0.012
negative regulation of protein maturation GO:1903318 142 0.012
cellular homeostasis GO:0019725 196 0.012
positive regulation of lipid biosynthetic process GO:0046889 22 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
spindle organization GO:0007051 53 0.012
positive regulation of organelle organization GO:0010638 195 0.012
regulation of protein catabolic process GO:0042176 155 0.012
regulation of cell activation GO:0050865 125 0.012
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of cell cycle GO:0051726 393 0.012
regulation of neuroblast proliferation GO:1902692 3 0.012
internal protein amino acid acetylation GO:0006475 101 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
pattern recognition receptor signaling pathway GO:0002221 48 0.012
endomembrane system organization GO:0010256 196 0.012
response to abiotic stimulus GO:0009628 336 0.012
nervous system development GO:0007399 293 0.012
atp metabolic process GO:0046034 176 0.012
response to insulin GO:0032868 45 0.012
cellular protein complex assembly GO:0043623 188 0.012
regulation of protein complex assembly GO:0043254 147 0.011
fatty acid biosynthetic process GO:0006633 46 0.011
sterol transport GO:0015918 39 0.011
negative regulation of proteolysis GO:0045861 132 0.011
positive regulation of innate immune response GO:0045089 79 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
peptidyl serine modification GO:0018209 106 0.011
organelle assembly GO:0070925 176 0.011
negative regulation of protein transport GO:0051224 75 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.011
dna templated transcription initiation GO:0006352 35 0.011
reproductive system development GO:0061458 56 0.011
reproductive structure development GO:0048608 55 0.011
hemopoiesis GO:0030097 180 0.011
positive regulation of triglyceride metabolic process GO:0090208 9 0.011
epithelium development GO:0060429 227 0.011
negative regulation of lipid storage GO:0010888 11 0.011
negative regulation of transferase activity GO:0051348 124 0.011
viral life cycle GO:0019058 132 0.011
actin cytoskeleton organization GO:0030036 207 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
regulation of growth GO:0040008 165 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
mitochondrial transport GO:0006839 60 0.010
viral process GO:0016032 146 0.010
regulation of dna metabolic process GO:0051052 153 0.010
positive regulation of cellular component movement GO:0051272 181 0.010
positive regulation of mitochondrial fission GO:0090141 7 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
regulation of homeostatic process GO:0032844 121 0.010
lipid storage GO:0019915 28 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
segmentation GO:0035282 4 0.010

EDF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.025
disease of cellular proliferation DOID:14566 174 0.025
organ system cancer DOID:0050686 164 0.016
endocrine gland cancer DOID:170 26 0.015