|
|
covalent chromatin modification
|
GO:0016569 |
254 |
1.000
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
1.000
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
1.000
|
|
|
|
histone h4 k8 acetylation
|
GO:0043982 |
15 |
1.000
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
1.000
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
1.000
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
1.000
|
Fly |
|
|
histone methylation
|
GO:0016571 |
60 |
1.000
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
1.000
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.999
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.998
|
Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.997
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.997
|
|
|
|
histone h4 k5 acetylation
|
GO:0043981 |
15 |
0.995
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.995
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.994
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.990
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
27 |
0.989
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.988
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.987
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.985
|
|
|
|
histone h4 k16 acetylation
|
GO:0043984 |
14 |
0.984
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.984
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.981
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.981
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.980
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.979
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.964
|
Yeast Zebrafish Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.961
|
Zebrafish Mouse |
|
|
peptidyl lysine methylation
|
GO:0018022 |
37 |
0.951
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.951
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.921
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.892
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.882
|
Zebrafish Mouse |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.879
|
|
|
|
histone h3 k4 trimethylation
|
GO:0080182 |
7 |
0.876
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.874
|
Zebrafish Mouse |
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.869
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.836
|
Zebrafish |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.823
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.817
|
Fly |
|
|
protein processing
|
GO:0016485 |
226 |
0.797
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.787
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.785
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.779
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
10 |
0.772
|
Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.752
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.722
|
Fly |
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.719
|
Yeast |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.689
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.685
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.680
|
Fly |
|
|
transdifferentiation
|
GO:0060290 |
2 |
0.668
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.667
|
Fly |
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.665
|
Yeast |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.663
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.657
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.654
|
Yeast Mouse |
|
|
gene silencing
|
GO:0016458 |
49 |
0.649
|
Yeast |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.642
|
Yeast |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.634
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.586
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.542
|
Yeast Mouse |
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.541
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.526
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.525
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.483
|
|
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
22 |
0.482
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.478
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.467
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.464
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.459
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.457
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.452
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.447
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.446
|
|
|
|
peptidyl lysine dimethylation
|
GO:0018027 |
3 |
0.438
|
Yeast |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.436
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.427
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.422
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.422
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.420
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.418
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.407
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.400
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.397
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.364
|
Fly |
|
|
dna repair
|
GO:0006281 |
198 |
0.347
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.347
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.347
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.346
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.340
|
Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.340
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.340
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.338
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.324
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.309
|
Yeast |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.308
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.307
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.304
|
Fly |
|
|
tube development
|
GO:0035295 |
125 |
0.298
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.291
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.284
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.281
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.281
|
Fly |
|
|
vasculature development
|
GO:0001944 |
181 |
0.280
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.279
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.279
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
31 |
0.278
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.271
|
Yeast Mouse |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.266
|
Fly |
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.264
|
Yeast |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.254
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.252
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.246
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.241
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.231
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.229
|
|
|
|
positive regulation of gluconeogenesis
|
GO:0045722 |
1 |
0.228
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
4 |
0.226
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.220
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.219
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.219
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.215
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.214
|
Yeast Fly |
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.213
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.213
|
|
|
|
aorta morphogenesis
|
GO:0035909 |
1 |
0.210
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.208
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.207
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.206
|
Fly |
|
|
gastrulation
|
GO:0007369 |
51 |
0.205
|
|
|
|
regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000095 |
2 |
0.200
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.200
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.197
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.192
|
Fly |
|
|
cellular senescence
|
GO:0090398 |
34 |
0.190
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.188
|
|
|
|
aorta development
|
GO:0035904 |
2 |
0.187
|
|
|
|
aging
|
GO:0007568 |
66 |
0.186
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.186
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.183
|
Yeast Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.181
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.179
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.178
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.177
|
|
|
|
regulation of histone h3 k4 methylation
|
GO:0051569 |
10 |
0.176
|
Mouse |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.175
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.174
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.171
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.169
|
|
|
|
growth
|
GO:0040007 |
202 |
0.168
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.167
|
Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.166
|
Fly |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.164
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.158
|
Fly |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.154
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.152
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.150
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.150
|
Yeast |
|
|
compound eye development
|
GO:0048749 |
1 |
0.149
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.148
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.145
|
|
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.141
|
|
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
13 |
0.138
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.137
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.136
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.136
|
Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.134
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.133
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.126
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.125
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.125
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.122
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.118
|
Fly |
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.117
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.117
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.114
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.113
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.112
|
Yeast Mouse |
|
|
rna splicing
|
GO:0008380 |
131 |
0.112
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.111
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.111
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.109
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.108
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.107
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.106
|
Mouse |
|
|
brain development
|
GO:0007420 |
97 |
0.105
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.104
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.102
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.102
|
Yeast |
|
|
protein stabilization
|
GO:0050821 |
64 |
0.101
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.099
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.098
|
Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.098
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.096
|
|
|
|
positive regulation of non canonical wnt signaling pathway
|
GO:2000052 |
3 |
0.096
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.092
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.091
|
|
|
|
regulation of methylation dependent chromatin silencing
|
GO:0090308 |
3 |
0.091
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.089
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.088
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.087
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.087
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.087
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.086
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.086
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.085
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.084
|
|
|
|
chromatin mediated maintenance of transcription
|
GO:0048096 |
2 |
0.083
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.083
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.081
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.080
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.080
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.079
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.078
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.077
|
Yeast |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.077
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.076
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.074
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.074
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.073
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.073
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.072
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.072
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.072
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.071
|
Fly |
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.071
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.071
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.071
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.071
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.070
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.069
|
|
|
|
positive regulation of glucose metabolic process
|
GO:0010907 |
12 |
0.068
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.068
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.067
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.067
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
8 |
0.066
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.064
|
Yeast Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.063
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.063
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.061
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.060
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.060
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.060
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.059
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.058
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.057
|
Yeast Fly |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.057
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.057
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.056
|
Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.055
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.055
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.055
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.055
|
Fly |
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.054
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.054
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.053
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.053
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.053
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.053
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.052
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.052
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.052
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.051
|
Mouse |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.051
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.050
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.050
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.049
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.048
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.048
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.047
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.046
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.046
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.046
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.045
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.045
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.045
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.044
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.044
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.044
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.043
|
|
|
|
positive regulation of transcription from rna polymerase iii promoter
|
GO:0045945 |
10 |
0.043
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.043
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.042
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.042
|
|
|
|
regulation of organ growth
|
GO:0046620 |
7 |
0.042
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.042
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.042
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.042
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.041
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.040
|
|
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.040
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.039
|
|
|
|
positive regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000096 |
2 |
0.039
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.038
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.038
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.038
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.038
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.038
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.037
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.037
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.037
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.037
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
10 |
0.036
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.036
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.036
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.036
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.035
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.035
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.035
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.034
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.033
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.033
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.033
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
4 |
0.033
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.033
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.033
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.033
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.032
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.032
|
Yeast |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.032
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.032
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.032
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.032
|
|
|
|
rna 3 end processing
|
GO:0031123 |
35 |
0.031
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.031
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.031
|
|
|
|
regulation of transcription by chromatin organization
|
GO:0034401 |
1 |
0.031
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.031
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.031
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.031
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.031
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.030
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.030
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.030
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.030
|
|
|
|
palate development
|
GO:0060021 |
13 |
0.030
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.029
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.029
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.029
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.028
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.028
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.028
|
Fly |
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.028
|
Yeast Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.028
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.028
|
|
|
|
learning or memory
|
GO:0007611 |
13 |
0.027
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.027
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.027
|
|
|
|
gamete generation
|
GO:0007276 |
25 |
0.027
|
Fly |
|
|
release from viral latency
|
GO:0019046 |
1 |
0.027
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.027
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.026
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.026
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.026
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.026
|
|
|
|
peptidyl lysine trimethylation
|
GO:0018023 |
10 |
0.026
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.026
|
|
|
|
mating
|
GO:0007618 |
1 |
0.026
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.026
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.026
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.025
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.025
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.025
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.025
|
|
|
|
limb morphogenesis
|
GO:0035108 |
16 |
0.025
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.024
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.024
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.024
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.024
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.024
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
9 |
0.024
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.023
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.023
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.023
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.023
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.023
|
|
|
|
system process
|
GO:0003008 |
349 |
0.023
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.022
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.022
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.022
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.022
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.022
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
21 |
0.022
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.022
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.022
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.022
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.021
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.021
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.021
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.021
|
Yeast |
|
|
cytokine production
|
GO:0001816 |
247 |
0.021
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.020
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.020
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.020
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.020
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.020
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.020
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.020
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.020
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.020
|
Yeast |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.020
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.020
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.020
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.019
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.019
|
|
|
|
positive regulation of mrna metabolic process
|
GO:1903313 |
19 |
0.019
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.019
|
|
|
|
memory
|
GO:0007613 |
3 |
0.019
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.019
|
|
|
|
organ induction
|
GO:0001759 |
4 |
0.019
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.019
|
Fly |
|
|
neurological system process
|
GO:0050877 |
163 |
0.019
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.019
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.019
|
|
|
|
regulation of transcription from rna polymerase i promoter
|
GO:0006356 |
10 |
0.019
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.019
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.018
|
|
|
|
regulation of cell size
|
GO:0008361 |
19 |
0.018
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.018
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.018
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.018
|
|
|
|
head development
|
GO:0060322 |
108 |
0.018
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.018
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.018
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.018
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.018
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.017
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.017
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.017
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.017
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.017
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.017
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.017
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.017
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.017
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.017
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.017
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.017
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.017
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.016
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.016
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
18 |
0.016
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.016
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.016
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.016
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.016
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.016
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.016
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.016
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.015
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.015
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.015
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.015
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.015
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.015
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.015
|
|
|
|
positive regulation of histone h3 k4 methylation
|
GO:0051571 |
8 |
0.015
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.015
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.015
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.015
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.015
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.015
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.015
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.015
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.014
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.014
|
|
|
|
regulation of mrna 3 end processing
|
GO:0031440 |
12 |
0.014
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.014
|
Zebrafish |
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.014
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.014
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.014
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.014
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.014
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.014
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.014
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.014
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.014
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.014
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.014
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.013
|
|
|
|
positive regulation of histone methylation
|
GO:0031062 |
12 |
0.013
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.013
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to oxidative stress
|
GO:0036091 |
3 |
0.013
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.013
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.013
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.013
|
|
