Homo sapiens

48 known processes

PKD2L1

polycystic kidney disease 2-like 1

(Aliases: TRPP3,PKD2L,PCL,PKDL)

PKD2L1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of sour taste GO:0050915 5 0.257
sensory perception of taste GO:0050909 36 0.140
sensory perception of chemical stimulus GO:0007606 38 0.118
system process GO:0003008 349 0.090
glycosyl compound catabolic process GO:1901658 413 0.082
purine nucleoside catabolic process GO:0006152 398 0.081
purine nucleoside triphosphate metabolic process GO:0009144 412 0.076
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.070
nucleoside triphosphate metabolic process GO:0009141 422 0.067
organophosphate catabolic process GO:0046434 430 0.065
nucleoside catabolic process GO:0009164 408 0.065
purine containing compound catabolic process GO:0072523 411 0.064
ribonucleoside triphosphate metabolic process GO:0009199 412 0.064
ribonucleoside catabolic process GO:0042454 406 0.064
purine nucleotide catabolic process GO:0006195 405 0.062
nucleotide catabolic process GO:0009166 408 0.061
purine ribonucleoside metabolic process GO:0046128 437 0.060
post embryonic development GO:0009791 2 0.060
nucleoside phosphate catabolic process GO:1901292 412 0.059
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.058
nucleoside triphosphate catabolic process GO:0009143 394 0.058
striated muscle contraction GO:0006941 52 0.058
ribonucleotide catabolic process GO:0009261 405 0.057
negative regulation of catalytic activity GO:0043086 335 0.056
ribonucleoside triphosphate catabolic process GO:0009203 391 0.055
regulation of purine nucleotide catabolic process GO:0033121 205 0.055
purine nucleoside monophosphate catabolic process GO:0009128 158 0.055
purine nucleoside monophosphate metabolic process GO:0009126 186 0.054
nucleoside monophosphate metabolic process GO:0009123 191 0.054
purine ribonucleotide catabolic process GO:0009154 404 0.053
negative regulation of phosphorus metabolic process GO:0010563 267 0.051
purine ribonucleoside catabolic process GO:0046130 398 0.048
cellular ketone metabolic process GO:0042180 80 0.047
regulation of purine nucleotide metabolic process GO:1900542 264 0.045
ribonucleoside monophosphate catabolic process GO:0009158 158 0.044
negative regulation of phosphate metabolic process GO:0045936 267 0.044
regulation of nucleotide catabolic process GO:0030811 205 0.044
regulation of nucleoside metabolic process GO:0009118 209 0.043
atp catabolic process GO:0006200 157 0.042
sensory perception GO:0007600 103 0.041
regulation of nucleotide metabolic process GO:0006140 269 0.041
negative regulation of hydrolase activity GO:0051346 182 0.040
ribonucleoside monophosphate metabolic process GO:0009161 187 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.040
atp metabolic process GO:0046034 176 0.040
neurological system process GO:0050877 163 0.039
cellular amine metabolic process GO:0044106 41 0.038
nucleoside monophosphate catabolic process GO:0009125 159 0.038
amine metabolic process GO:0009308 44 0.038
multicellular organismal aging GO:0010259 3 0.037
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.037
cellular amino acid metabolic process GO:0006520 116 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.035
regulation of cellular amine metabolic process GO:0033238 11 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
determination of adult lifespan GO:0008340 2 0.032
cardiac muscle contraction GO:0060048 34 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.030
female gamete generation GO:0007292 2 0.029
ras protein signal transduction GO:0007265 73 0.029
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
oogenesis GO:0048477 2 0.028
locomotory behavior GO:0007626 1 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
cardiovascular system development GO:0072358 262 0.027
lipid metabolic process GO:0006629 381 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
rho protein signal transduction GO:0007266 26 0.026
skeletal muscle contraction GO:0003009 16 0.025
regulation of atp metabolic process GO:1903578 29 0.025
cation transport GO:0006812 331 0.024
muscle system process GO:0003012 81 0.024
regulation of atpase activity GO:0043462 25 0.024
defense response GO:0006952 315 0.024
negative regulation of catabolic process GO:0009895 104 0.024
positive regulation of cellular component organization GO:0051130 376 0.024
transmembrane transport GO:0055085 399 0.023
regulation of proteolysis GO:0030162 293 0.023
cellular protein catabolic process GO:0044257 261 0.022
neuromuscular junction development GO:0007528 3 0.022
protein catabolic process GO:0030163 325 0.022
response to oxygen containing compound GO:1901700 369 0.022
muscle contraction GO:0006936 73 0.021
cytoplasmic transport GO:0016482 379 0.021
segmentation GO:0035282 4 0.021
negative regulation of nucleotide catabolic process GO:0030812 16 0.021
immune response GO:0006955 307 0.021
membrane organization GO:0061024 292 0.020
single organism cellular localization GO:1902580 332 0.020
apoptotic signaling pathway GO:0097190 268 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
ion transmembrane transport GO:0034220 338 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
negative regulation of cellular catabolic process GO:0031330 83 0.020
cellular lipid metabolic process GO:0044255 303 0.020
single organism membrane organization GO:0044802 268 0.020
regulation of kinase activity GO:0043549 314 0.020
positive regulation of catabolic process GO:0009896 310 0.020
cardiac ventricle morphogenesis GO:0003208 20 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
circulatory system development GO:0072359 262 0.020
cellular macromolecule catabolic process GO:0044265 380 0.019
musculoskeletal movement GO:0050881 17 0.019
regulation of cellular response to stress GO:0080135 244 0.019
vesicle mediated transport GO:0016192 371 0.019
circulatory system process GO:0003013 113 0.018
spermatid differentiation GO:0048515 4 0.018
regulation of protein kinase activity GO:0045859 289 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
multicellular organismal movement GO:0050879 17 0.018
biological adhesion GO:0022610 331 0.018
actin filament based process GO:0030029 224 0.018
dephosphorylation GO:0016311 209 0.018
regulation of transferase activity GO:0051338 355 0.018
nitrogen compound transport GO:0071705 191 0.018
cellular macromolecular complex assembly GO:0034622 324 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
protein localization to organelle GO:0033365 280 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
protein processing GO:0016485 226 0.017
protein ubiquitination GO:0016567 314 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
cell morphogenesis GO:0000902 296 0.017
secretion GO:0046903 254 0.017
cardiac chamber morphogenesis GO:0003206 26 0.017
mitotic cell cycle GO:0000278 326 0.017
regulation of mapk cascade GO:0043408 262 0.017
oxidation reduction process GO:0055114 396 0.017
negative regulation of protein modification process GO:0031400 200 0.017
protein maturation GO:0051604 233 0.017
memory GO:0007613 3 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
innate immune response GO:0045087 178 0.016
oocyte development GO:0048599 1 0.016
regeneration GO:0031099 4 0.016
regulation of protein localization GO:0032880 296 0.016
oocyte differentiation GO:0009994 2 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
regulation of atp catabolic process GO:1903289 25 0.016
regulation of cell differentiation GO:0045595 393 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
negative regulation of cell death GO:0060548 345 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
nervous system development GO:0007399 293 0.016
spermatid development GO:0007286 4 0.016
regulation of cell cycle GO:0051726 393 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
hindbrain development GO:0030902 3 0.016
organ morphogenesis GO:0009887 147 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
response to abiotic stimulus GO:0009628 336 0.016
positive regulation of immune system process GO:0002684 283 0.016
chemical homeostasis GO:0048878 306 0.016
ion homeostasis GO:0050801 230 0.015
tissue morphogenesis GO:0048729 96 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
positive regulation of cell death GO:0010942 263 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
positive regulation of transferase activity GO:0051347 227 0.015
regulation of intracellular transport GO:0032386 195 0.015
cardiac chamber development GO:0003205 30 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
mitotic cell cycle process GO:1903047 286 0.015
gtp metabolic process GO:0046039 239 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
blastoderm segmentation GO:0007350 2 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
carbohydrate metabolic process GO:0005975 207 0.015
nerve development GO:0021675 4 0.015
maintenance of location GO:0051235 112 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
response to external biotic stimulus GO:0043207 261 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
protein oligomerization GO:0051259 173 0.015
regulation of response to external stimulus GO:0032101 222 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
positive regulation of cell proliferation GO:0008284 301 0.014
positive regulation of organelle organization GO:0010638 195 0.014
regulation of peptidase activity GO:0052547 180 0.014
cell adhesion GO:0007155 325 0.014
anion transport GO:0006820 161 0.014
intracellular protein transport GO:0006886 270 0.014
heart process GO:0003015 62 0.014
positive regulation of transport GO:0051050 336 0.014
cellular protein complex assembly GO:0043623 188 0.014
protein targeting GO:0006605 187 0.014
response to biotic stimulus GO:0009607 276 0.014
anterior posterior axis specification GO:0009948 2 0.014
heart contraction GO:0060047 62 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
cell development GO:0048468 328 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
cytokine production GO:0001816 247 0.014
regulation of protein transport GO:0051223 213 0.014
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.014
chromatin organization GO:0006325 351 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
lipid biosynthetic process GO:0008610 177 0.014
regulation of cellular component movement GO:0051270 334 0.014
regulation of cell cycle process GO:0010564 266 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
gtp catabolic process GO:0006184 237 0.013
compound eye development GO:0048749 1 0.013
heart morphogenesis GO:0003007 48 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
regulation of immune response GO:0050776 201 0.013
cation homeostasis GO:0055080 189 0.013
metal ion transport GO:0030001 272 0.013
response to cytokine GO:0034097 232 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
regulation of gtpase activity GO:0043087 180 0.013
tripartite regional subdivision GO:0007351 2 0.013
peripheral nervous system development GO:0007422 2 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
sensory perception of smell GO:0007608 2 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
rna processing GO:0006396 255 0.013
blood circulation GO:0008015 113 0.013
dna repair GO:0006281 198 0.013
cellular component morphogenesis GO:0032989 314 0.013
neuroblast proliferation GO:0007405 4 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of protein processing GO:0070613 150 0.013
small molecule biosynthetic process GO:0044283 157 0.013
response to other organism GO:0051707 261 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
adult locomotory behavior GO:0008344 1 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
response to fungus GO:0009620 4 0.012
regulation of protein maturation GO:1903317 150 0.012
nuclear transport GO:0051169 179 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
regulation of cell migration GO:0030334 289 0.012
negative regulation of developmental process GO:0051093 247 0.012
cell fate determination GO:0001709 3 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
endomembrane system organization GO:0010256 196 0.012
negative regulation of cell cycle GO:0045786 193 0.012
negative regulation of protein processing GO:0010955 142 0.012
mapk cascade GO:0000165 288 0.012
regulation of secretion by cell GO:1903530 177 0.012
immune system development GO:0002520 195 0.012
regulation of locomotion GO:0040012 329 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of cell motility GO:2000145 299 0.012
protein localization to membrane GO:0072657 160 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
cell growth GO:0016049 160 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
cation transmembrane transport GO:0098655 238 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
interspecies interaction between organisms GO:0044419 156 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
positive regulation of kinase activity GO:0033674 204 0.012
cardiac ventricle development GO:0003231 23 0.012
regulation of cytokine production GO:0001817 232 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
microtubule based process GO:0007017 210 0.012
multi organism cellular process GO:0044764 156 0.012
cranial nerve development GO:0021545 4 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
secretion by cell GO:0032940 226 0.011
positive regulation of proteolysis GO:0045862 142 0.011
regulation of protein complex assembly GO:0043254 147 0.011
chromatin modification GO:0016568 298 0.011
sensory perception of pain GO:0019233 4 0.011
organelle assembly GO:0070925 176 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
muscle tissue development GO:0060537 62 0.011
covalent chromatin modification GO:0016569 254 0.011
striated muscle tissue development GO:0014706 59 0.011
cardiac muscle tissue development GO:0048738 39 0.011
cell cycle phase transition GO:0044770 173 0.011
growth GO:0040007 202 0.011
positive regulation of cytokine production GO:0001819 167 0.011
metencephalon development GO:0022037 2 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
defense response to other organism GO:0098542 129 0.011
regulation of cell growth GO:0001558 135 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
histone modification GO:0016570 251 0.011
actin filament based movement GO:0030048 17 0.011
muscle tissue morphogenesis GO:0060415 19 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
positive regulation of immune response GO:0050778 159 0.011
regulation of actin filament based process GO:0032970 141 0.011
cell division GO:0051301 168 0.011
regulation of dna metabolic process GO:0051052 153 0.011
regulation of protein catabolic process GO:0042176 155 0.011
negative regulation of proteolysis GO:0045861 132 0.011
associative learning GO:0008306 1 0.011
wnt signaling pathway GO:0016055 156 0.011
negative regulation of transferase activity GO:0051348 124 0.011
cell projection organization GO:0030030 252 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
regulation of defense response GO:0031347 154 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
viral process GO:0016032 146 0.011
sequestering of metal ion GO:0051238 24 0.011
cell activation GO:0001775 213 0.011
actin cytoskeleton organization GO:0030036 207 0.011
metal ion homeostasis GO:0055065 169 0.011
negative regulation of synaptic transmission GO:0050805 2 0.011
response to nitrogen compound GO:1901698 184 0.011
sequestering of calcium ion GO:0051208 17 0.011
cell projection assembly GO:0030031 126 0.011
cellular cation homeostasis GO:0030003 163 0.011
hemopoiesis GO:0030097 180 0.011
negative regulation of nucleotide metabolic process GO:0045980 29 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
heart development GO:0007507 95 0.011
ventricular cardiac muscle tissue development GO:0003229 14 0.011
muscle structure development GO:0061061 98 0.011
endosomal transport GO:0016197 129 0.011
single organism cell adhesion GO:0098602 179 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
rhythmic behavior GO:0007622 2 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
negative regulation of protein maturation GO:1903318 142 0.010
fatty acid metabolic process GO:0006631 115 0.010
neural crest cell development GO:0014032 3 0.010
glial cell migration GO:0008347 4 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
neural tube formation GO:0001841 3 0.010
blood vessel morphogenesis GO:0048514 162 0.010
cellular homeostasis GO:0019725 196 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
negative regulation of organelle organization GO:0010639 126 0.010
meiotic chromosome segregation GO:0045132 4 0.010
organic anion transport GO:0015711 103 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
circadian behavior GO:0048512 2 0.010
response to inorganic substance GO:0010035 127 0.010
neurogenesis GO:0022008 169 0.010
regulation of cell adhesion GO:0030155 166 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
mating GO:0007618 1 0.010
visual behavior GO:0007632 2 0.010
glycoprotein metabolic process GO:0009100 110 0.010
negative regulation of immune system process GO:0002683 136 0.010
sulfur compound metabolic process GO:0006790 101 0.010
primary neural tube formation GO:0014020 3 0.010
organ formation GO:0048645 3 0.010

PKD2L1 disease predictions

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 104 0.078
muscular disease DOID:0080000 114 0.078
musculoskeletal system disease DOID:17 223 0.078
muscle tissue disease DOID:66 113 0.078
heart disease DOID:114 68 0.060
cardiovascular system disease DOID:1287 106 0.060
cardiomyopathy DOID:0050700 50 0.029
intrinsic cardiomyopathy DOID:0060036 50 0.029
sensory system disease DOID:0050155 203 0.028
nervous system disease DOID:863 431 0.028
dilated cardiomyopathy DOID:12930 32 0.028
hypertrophic cardiomyopathy DOID:11984 21 0.025
disease of metabolism DOID:0014667 295 0.023
eye and adnexa disease DOID:1492 150 0.020
central nervous system disease DOID:331 186 0.019
eye disease DOID:5614 149 0.019
inherited metabolic disorder DOID:655 242 0.018
retinal disease DOID:5679 118 0.015
disease of cellular proliferation DOID:14566 174 0.013
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.013
connective tissue disease DOID:65 109 0.012
retinal degeneration DOID:8466 89 0.011
neurodegenerative disease DOID:1289 102 0.011