|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.707
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.698
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.634
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.595
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.547
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.518
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.515
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.485
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.476
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.470
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.464
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.451
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.448
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.446
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.444
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.441
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.433
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.430
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.420
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.402
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.387
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.381
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.375
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.373
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.371
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.370
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.361
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.359
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.357
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.356
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.354
|
|
|
|
negative regulation of heterotypic cell cell adhesion
|
GO:0034115 |
6 |
0.350
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.343
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.323
|
|
|
|
positive regulation of p38mapk cascade
|
GO:1900745 |
8 |
0.317
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.308
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.306
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.305
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.291
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.286
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
9 |
0.279
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.278
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.277
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.273
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.263
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.261
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.257
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.257
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.257
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.254
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.252
|
|
|
|
growth
|
GO:0040007 |
202 |
0.249
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.247
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.246
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.245
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.239
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.236
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.233
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.231
|
|
|
|
negative regulation of chemokine c x c motif ligand 2 production
|
GO:2000342 |
1 |
0.231
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.225
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.223
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.222
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.217
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.211
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.209
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.208
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.207
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.207
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.206
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.200
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.197
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.195
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.193
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.189
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.188
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.188
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.188
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.186
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.185
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.185
|
|
|
|
regulation of chemokine c x c motif ligand 2 production
|
GO:2000341 |
2 |
0.184
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.183
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.182
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.180
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.180
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.179
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.178
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.177
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.175
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.174
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.173
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.172
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.171
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.171
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.170
|
|
|
|
regulation of cell cell adhesion involved in gastrulation
|
GO:0070587 |
6 |
0.169
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.167
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.167
|
|
|
|
regulation of heterotypic cell cell adhesion
|
GO:0034114 |
14 |
0.166
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.166
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.164
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.162
|
|
|
|
negative regulation of cell migration involved in sprouting angiogenesis
|
GO:0090051 |
6 |
0.161
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.157
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.157
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.156
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.153
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.150
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.150
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.149
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.148
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.147
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.147
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.144
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.143
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.143
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.143
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.142
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.139
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.139
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.138
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.138
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.138
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.136
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.136
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.135
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.135
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.133
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.131
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.129
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.128
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.127
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.127
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.127
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.126
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.122
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.122
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.121
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.121
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.119
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.119
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.118
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.115
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.114
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.114
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.113
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.113
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.112
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.112
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.112
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.112
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.112
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.111
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.109
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.107
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.105
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.105
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.105
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.105
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.102
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
9 |
0.102
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.101
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.100
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.098
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.097
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.097
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.097
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.096
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.096
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.095
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.095
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.093
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.093
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.093
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.093
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.093
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.090
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.090
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.090
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.089
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.089
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.089
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.088
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.088
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.087
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.087
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.086
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.086
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.085
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.084
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.083
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.082
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.082
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.082
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.081
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.081
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.080
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.079
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.078
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.077
|
|
|
|
erk5 cascade
|
GO:0070375 |
1 |
0.077
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.077
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.076
|
|
|
|
cell cell adhesion involved in gastrulation
|
GO:0070586 |
6 |
0.076
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.075
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.075
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.074
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.073
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.072
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.072
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.072
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.072
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.071
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.071
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.070
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.070
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.070
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.070
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.069
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.068
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.067
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.066
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.065
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.065
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.064
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.064
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.063
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.062
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.061
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.061
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.060
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.060
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.060
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.060
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.059
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.059
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.059
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.059
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.059
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.059
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.058
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.058
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.058
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.058
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.057
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.057
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.057
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.057
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.057
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.057
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.056
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.056
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.056
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.055
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.055
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.055
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.054
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.054
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.053
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.053
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.052
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.052
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.051
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.051
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.051
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.051
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.050
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.050
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.050
|
Human |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.050
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.049
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.048
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.048
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.048
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.048
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.047
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.047
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.047
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.047
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.047
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.047
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.046
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.046
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.046
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.046
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.045
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.045
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.045
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.044
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.043
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.043
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.043
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.043
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.042
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.042
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.042
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.041
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.041
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.041
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.041
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.041
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.040
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.040
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.040
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.040
|
Human |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.040
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.040
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.039
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.039
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.038
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.038
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.038
|
|
|
|
regulation of interleukin 8 biosynthetic process
|
GO:0045414 |
11 |
0.038
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.038
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.037
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.037
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.037
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.037
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.036
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.036
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.036
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.036
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.036
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.036
|
|
|
|
regulation of gastrulation
|
GO:0010470 |
12 |
0.036
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.036
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.036
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.035
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.035
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.035
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.034
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.034
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.034
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.034
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.034
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.034
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.034
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.033
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.033
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.033
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.033
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.033
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.033
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.033
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.033
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.033
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.033
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.033
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.033
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.032
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.032
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.032
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.032
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.031
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.031
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.031
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.031
|
|
|
|
receptor catabolic process
|
GO:0032801 |
11 |
0.031
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.031
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.031
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.030
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.030
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.030
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.030
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.029
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.029
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.029
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.029
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.029
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.029
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.028
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.028
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.028
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.028
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.028
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.028
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.028
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.027
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.027
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.027
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.027
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.027
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.026
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.026
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.026
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.026
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.026
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.026
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.026
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.026
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.026
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.026
|
|
|
|
cellular response to misfolded protein
|
GO:0071218 |
2 |
0.026
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.026
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.025
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.025
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.025
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.025
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.025
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.025
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.025
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.025
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.025
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.025
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.025
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.025
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.025
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.024
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.024
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.024
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.024
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.024
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.024
|
|
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
27 |
0.024
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.024
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.024
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.024
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.023
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.023
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.023
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.023
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.023
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.023
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.023
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.023
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.023
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.023
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.022
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.022
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.022
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.022
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.022
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.022
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.022
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.022
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.022
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.022
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.022
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.021
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.021
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.021
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.021
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.021
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.021
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.021
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.021
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.021
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.021
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.021
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.021
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.021
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.021
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.021
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.020
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.020
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.020
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.020
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.020
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.020
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.020
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.020
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.020
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.020
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.020
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.020
|
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
12 |
0.020
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.020
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.020
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.020
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.020
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.019
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.019
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.019
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.019
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.019
|
|
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.019
|
|
|
|
mechanosensory behavior
|
GO:0007638 |
4 |
0.019
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.019
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.019
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.019
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.019
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.019
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.019
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.019
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.018
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.018
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.018
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.018
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.018
|
|
|
|
system process
|
GO:0003008 |
349 |
0.018
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.018
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.018
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.018
|
|
