Homo sapiens

170 known processes

MAP3K7

mitogen-activated protein kinase kinase kinase 7

(Aliases: TGF1a,TAK1,MEKK7)

MAP3K7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
i kappab kinase nf kappab signaling GO:0007249 166 1.000
regulation of i kappab kinase nf kappab signaling GO:0043122 162 1.000
signal transduction by phosphorylation GO:0023014 297 0.999
regulation of stress activated mapk cascade GO:0032872 84 0.999
protein autophosphorylation GO:0046777 123 0.999
Worm
response to cytokine GO:0034097 232 0.999
negative regulation of apoptotic process GO:0043066 316 0.998
Mouse
regulation of mapk cascade GO:0043408 262 0.998
regulation of jnk cascade GO:0046328 73 0.997
positive regulation of protein phosphorylation GO:0001934 313 0.996
regulation of protein kinase activity GO:0045859 289 0.995
nik nf kappab signaling GO:0038061 12 0.995
protein ubiquitination GO:0016567 314 0.995
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.995
response to other organism GO:0051707 261 0.995
Fly
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.995
positive regulation of kinase activity GO:0033674 204 0.994
activation of protein kinase activity GO:0032147 90 0.993
positive regulation of transferase activity GO:0051347 227 0.992
regulation of kinase activity GO:0043549 314 0.991
positive regulation of protein kinase activity GO:0045860 190 0.988
regulation of transferase activity GO:0051338 355 0.986
modification dependent protein catabolic process GO:0019941 209 0.986
multicellular organismal aging GO:0010259 3 0.977
positive regulation of mapk cascade GO:0043410 190 0.974
positive regulation of phosphorylation GO:0042327 394 0.971
jnk cascade GO:0007254 80 0.970
negative regulation of intracellular signal transduction GO:1902532 183 0.970
stress activated protein kinase signaling cascade GO:0031098 94 0.965
peptidyl serine phosphorylation GO:0018105 101 0.960
positive regulation of cytokine production GO:0001819 167 0.959
peptidyl serine modification GO:0018209 106 0.955
cytokine mediated signaling pathway GO:0019221 109 0.939
covalent chromatin modification GO:0016569 254 0.938
actin filament based process GO:0030029 224 0.934
ubiquitin dependent protein catabolic process GO:0006511 206 0.934
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.921
mapk cascade GO:0000165 288 0.918
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.914
regulation of microtubule based process GO:0032886 74 0.902
innate immune response GO:0045087 178 0.896
response to growth factor GO:0070848 205 0.892
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.891
response to external biotic stimulus GO:0043207 261 0.891
Fly
peptidyl threonine phosphorylation GO:0018107 41 0.887
positive regulation of immune system process GO:0002684 283 0.886
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.874
regulation of apoptotic signaling pathway GO:2001233 175 0.872
Mouse
regulation of protein localization GO:0032880 296 0.871
response to biotic stimulus GO:0009607 276 0.863
Fly
regulation of defense response GO:0031347 154 0.861
Fly
positive regulation of response to external stimulus GO:0032103 88 0.857
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.844
Mouse Worm
microtubule cytoskeleton organization GO:0000226 176 0.843
serine phosphorylation of stat protein GO:0042501 4 0.834
cellular response to cytokine stimulus GO:0071345 181 0.823
negative regulation of protein metabolic process GO:0051248 391 0.823
regulation of immune effector process GO:0002697 91 0.817
protein targeting GO:0006605 187 0.799
cardiovascular system development GO:0072358 262 0.795
Zebrafish Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.793
t cell cytokine production GO:0002369 12 0.792
cytokine production GO:0001816 247 0.785
protein localization to organelle GO:0033365 280 0.771
chromatin modification GO:0016568 298 0.762
intracellular protein transport GO:0006886 270 0.748
regulation of protein ubiquitination GO:0031396 95 0.739
post embryonic development GO:0009791 2 0.726
Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.721
regulation of immune response GO:0050776 201 0.716
microtubule based process GO:0007017 210 0.715
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.714
negative regulation of programmed cell death GO:0043069 321 0.713
Mouse
cellular protein catabolic process GO:0044257 261 0.710
cellular macromolecule catabolic process GO:0044265 380 0.699
positive regulation of immune response GO:0050778 159 0.684
positive regulation of cellular component organization GO:0051130 376 0.684
response to virus GO:0009615 126 0.675
Fly
protein catabolic process GO:0030163 325 0.671
protein modification by small protein conjugation GO:0032446 342 0.662
response to wounding GO:0009611 168 0.658
negative regulation of mapk cascade GO:0043409 56 0.653
negative regulation of protein modification process GO:0031400 200 0.648
mitotic cell cycle GO:0000278 326 0.648
apoptotic signaling pathway GO:0097190 268 0.629
Mouse
positive regulation of stress activated mapk cascade GO:0032874 60 0.608
regulation of cytoskeleton organization GO:0051493 177 0.598
nuclear transport GO:0051169 179 0.597
negative regulation of phosphorus metabolic process GO:0010563 267 0.591
embryo development GO:0009790 123 0.565
Mouse Worm Fly
regulation of map kinase activity GO:0043405 108 0.563
determination of adult lifespan GO:0008340 2 0.553
positive regulation of developmental process GO:0051094 314 0.549
negative regulation of protein phosphorylation GO:0001933 140 0.538
positive regulation of cell death GO:0010942 263 0.536
leukocyte differentiation GO:0002521 98 0.533
regulation of protein serine threonine kinase activity GO:0071900 179 0.526
immune effector process GO:0002252 159 0.515
regulation of cytokine production GO:0001817 232 0.513
regulation of ion transport GO:0043269 189 0.511
cellular component disassembly GO:0022411 92 0.509
neural tube formation GO:0001841 3 0.503
Mouse
stress activated mapk cascade GO:0051403 93 0.500
regulation of jun kinase activity GO:0043506 27 0.494
response to abiotic stimulus GO:0009628 336 0.487
cell development GO:0048468 328 0.453
regulation of secretion GO:0051046 194 0.451
cellular response to oxidative stress GO:0034599 85 0.448
single organism cellular localization GO:1902580 332 0.443
positive regulation of catabolic process GO:0009896 310 0.441
activation of jnkk activity GO:0007256 1 0.437
Fly
positive regulation of jun kinase activity GO:0043507 23 0.436
protein import GO:0017038 130 0.431
negative regulation of jnk cascade GO:0046329 16 0.423
regulation of proteolysis GO:0030162 293 0.412
negative regulation of stress activated mapk cascade GO:0032873 19 0.407
regulation of response to external stimulus GO:0032101 222 0.405
Fly
response to oxidative stress GO:0006979 121 0.395
dephosphorylation GO:0016311 209 0.386
cellular macromolecular complex assembly GO:0034622 324 0.383
histone modification GO:0016570 251 0.380
intrinsic apoptotic signaling pathway GO:0097193 127 0.379
positive regulation of defense response GO:0031349 87 0.377
Fly
cellular response to endogenous stimulus GO:0071495 336 0.376
Mouse
response to tumor necrosis factor GO:0034612 76 0.376
cytokine production involved in immune response GO:0002367 27 0.362
defense response to bacterium GO:0042742 63 0.361
Fly
regulation of establishment of protein localization GO:0070201 242 0.358
ion homeostasis GO:0050801 230 0.355
nervous system development GO:0007399 293 0.343
Mouse
negative regulation of map kinase activity GO:0043407 27 0.335
cellular protein complex assembly GO:0043623 188 0.333
neuromuscular junction development GO:0007528 3 0.329
circulatory system development GO:0072359 262 0.325
Zebrafish Mouse
actin cytoskeleton organization GO:0030036 207 0.323
positive regulation of map kinase activity GO:0043406 80 0.321
positive regulation of cellular component movement GO:0051272 181 0.319
negative regulation of cell death GO:0060548 345 0.305
Mouse
positive regulation of chromatin modification GO:1903310 30 0.304
regulation of adaptive immune response GO:0002819 33 0.302
single organism membrane organization GO:0044802 268 0.294
positive regulation of nik nf kappab signaling GO:1901224 10 0.290
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.288
jak stat cascade GO:0007259 46 0.288
regulation of cellular component movement GO:0051270 334 0.284
negative regulation of protein processing GO:0010955 142 0.282
cellular response to growth factor stimulus GO:0071363 197 0.276
Mouse
axon cargo transport GO:0008088 2 0.270
positive regulation of jnk cascade GO:0046330 52 0.264
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.259
multicellular organismal homeostasis GO:0048871 67 0.259
secretion GO:0046903 254 0.257
positive regulation of cell proliferation GO:0008284 301 0.250
response to molecule of bacterial origin GO:0002237 82 0.250
Fly
negative regulation of protein ubiquitination GO:0031397 35 0.246
neurogenesis GO:0022008 169 0.241
negative regulation of jun kinase activity GO:0043508 4 0.232
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.232
Mouse
negative regulation of phosphorylation GO:0042326 174 0.231
protein folding GO:0006457 38 0.231
negative regulation of catalytic activity GO:0043086 335 0.229
protein localization to nucleus GO:0034504 136 0.227
cellular response to dna damage stimulus GO:0006974 379 0.224
system process GO:0003008 349 0.222
protein oligomerization GO:0051259 173 0.220
cellular response to tumor necrosis factor GO:0071356 63 0.218
positive regulation of cell differentiation GO:0045597 211 0.217
ncrna metabolic process GO:0034660 108 0.217
defense response GO:0006952 315 0.217
Worm Fly
regulation of microtubule cytoskeleton organization GO:0070507 61 0.214
aging GO:0007568 66 0.211
photoreceptor cell maintenance GO:0045494 13 0.206
regulation of meiotic cell cycle GO:0051445 4 0.203
organelle localization GO:0051640 84 0.202
positive regulation of production of molecular mediator of immune response GO:0002702 11 0.202
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.200
Mouse
regulation of cytokine mediated signaling pathway GO:0001959 41 0.196
positive regulation of immune effector process GO:0002699 40 0.196
regulation of cellular response to stress GO:0080135 244 0.195
regulation of protein transport GO:0051223 213 0.194
regulation of cell activation GO:0050865 125 0.193
positive regulation of organelle organization GO:0010638 195 0.192
proteasomal protein catabolic process GO:0010498 176 0.182
peptidyl threonine modification GO:0018210 45 0.176
positive regulation of innate immune response GO:0045089 79 0.175
regulation of reactive oxygen species metabolic process GO:2000377 41 0.168
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.168
cell aging GO:0007569 52 0.165
regulation of endopeptidase activity GO:0052548 170 0.164
neurotransmitter secretion GO:0007269 4 0.164
rho protein signal transduction GO:0007266 26 0.159
immune response GO:0006955 307 0.154
tube development GO:0035295 125 0.153
Mouse Worm
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.151
positive regulation of cell development GO:0010720 92 0.150
activation of jun kinase activity GO:0007257 7 0.141
Fly
regulation of cellular protein catabolic process GO:1903362 96 0.140
regulation of protein targeting GO:1903533 91 0.136
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.133
chromatin organization GO:0006325 351 0.132
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.131
regulation of neuron death GO:1901214 56 0.128
mitotic cell cycle process GO:1903047 286 0.128
regulation of jak stat cascade GO:0046425 44 0.128
hematopoietic or lymphoid organ development GO:0048534 186 0.127
regulation of innate immune response GO:0045088 97 0.126
regulation of protein maturation GO:1903317 150 0.124
digestive tract morphogenesis GO:0048546 56 0.123
Worm
organelle fission GO:0048285 149 0.122
ribonucleoside triphosphate metabolic process GO:0009199 412 0.120
regulation of protein processing GO:0070613 150 0.120
regulation of leukocyte mediated immunity GO:0002703 38 0.119
regulation of t cell cytokine production GO:0002724 10 0.119
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.119
regulation of peptidase activity GO:0052547 180 0.118
positive regulation of cell cycle GO:0045787 140 0.116
cell projection morphogenesis GO:0048858 129 0.115
regulation of cell differentiation GO:0045595 393 0.113
vasodilation GO:0042311 4 0.113
protein homooligomerization GO:0051260 100 0.113
regulation of actin filament based process GO:0032970 141 0.112
regulation of protein complex assembly GO:0043254 147 0.111
Mouse
positive regulation of programmed cell death GO:0043068 249 0.111
gtp catabolic process GO:0006184 237 0.111
activation of mapk activity GO:0000187 45 0.110
modification dependent macromolecule catabolic process GO:0043632 212 0.109
response to bacterium GO:0009617 144 0.108
Fly
protein maturation GO:0051604 233 0.108
positive regulation of leukocyte activation GO:0002696 80 0.107
negative regulation of multicellular organismal process GO:0051241 317 0.106
establishment of protein localization to mitochondrion GO:0072655 22 0.106
erk1 and erk2 cascade GO:0070371 104 0.106
positive regulation of cellular catabolic process GO:0031331 284 0.105
regulation of proteasomal protein catabolic process GO:0061136 87 0.105
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.104
positive regulation of t cell cytokine production GO:0002726 4 0.102
cellular response to molecule of bacterial origin GO:0071219 62 0.101
Fly
regulation of nik nf kappab signaling GO:1901222 11 0.101
spindle organization GO:0007051 53 0.101
response to hydrogen peroxide GO:0042542 40 0.101
regulation of interleukin 1 mediated signaling pathway GO:2000659 3 0.100
immune system development GO:0002520 195 0.099
negative regulation of kinase activity GO:0033673 106 0.098
cytoplasmic transport GO:0016482 379 0.098
neuron differentiation GO:0030182 138 0.097
response to lipid GO:0033993 206 0.096
Fly
regulation of protein localization to nucleus GO:1900180 85 0.094
positive regulation of t cell activation GO:0050870 54 0.093
ncrna processing GO:0034470 83 0.092
myeloid cell differentiation GO:0030099 117 0.091
positive regulation of adaptive immune response GO:0002821 21 0.090
tissue homeostasis GO:0001894 63 0.089
vesicle mediated transport GO:0016192 371 0.089
growth GO:0040007 202 0.088
regulation of cell morphogenesis GO:0022604 153 0.088
establishment of organelle localization GO:0051656 59 0.087
actin filament organization GO:0007015 128 0.087
cellular response to metal ion GO:0071248 43 0.085
negative regulation of cellular component organization GO:0051129 235 0.084
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 70 0.082
secretion by cell GO:0032940 226 0.082
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.082
positive regulation of meiotic cell cycle GO:0051446 2 0.082
lymphocyte homeostasis GO:0002260 4 0.081
neuron development GO:0048666 113 0.081
cellular component morphogenesis GO:0032989 314 0.081
regulation of nucleocytoplasmic transport GO:0046822 98 0.081
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.080
regulation of t cell mediated immunity GO:0002709 18 0.079
positive regulation of protein ubiquitination GO:0031398 53 0.079
metal ion transport GO:0030001 272 0.079
regulation of small gtpase mediated signal transduction GO:0051056 156 0.078
positive regulation of multi organism process GO:0043902 56 0.078
Fly
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.078
regulation of metal ion transport GO:0010959 120 0.077
enzyme linked receptor protein signaling pathway GO:0007167 303 0.075
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.074
regulation of protein catabolic process GO:0042176 155 0.074
response to mechanical stimulus GO:0009612 51 0.074
cellular response to mechanical stimulus GO:0071260 39 0.073
ribonucleoprotein complex biogenesis GO:0022613 116 0.072
ossification GO:0001503 121 0.071
response to oxygen containing compound GO:1901700 369 0.071
Fly
mitotic cell cycle phase transition GO:0044772 162 0.071
cell growth GO:0016049 160 0.070
regulation of chromosome organization GO:0033044 103 0.070
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.067
muscle cell differentiation GO:0042692 63 0.066
Worm
cilium morphogenesis GO:0060271 75 0.065
cell part morphogenesis GO:0032990 137 0.064
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.063
nucleotide catabolic process GO:0009166 408 0.063
regulation of protein import into nucleus GO:0042306 78 0.063
neuron projection development GO:0031175 106 0.062
negative regulation of protein maturation GO:1903318 142 0.062
ribonucleoprotein complex subunit organization GO:0071826 81 0.060
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.060
regulation of autophagy GO:0010506 52 0.060
Fly
protein k48 linked ubiquitination GO:0070936 38 0.059
mitochondrion organization GO:0007005 156 0.059
histone acetylation GO:0016573 93 0.057
lipid metabolic process GO:0006629 381 0.056
ras protein signal transduction GO:0007265 73 0.056
retina homeostasis GO:0001895 42 0.056
heart process GO:0003015 62 0.056
generation of neurons GO:0048699 152 0.056
histone serine phosphorylation GO:0035404 4 0.055
positive regulation of hydrolase activity GO:0051345 331 0.055
tor signaling GO:0031929 39 0.055
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.055
Mouse
embryo development ending in birth or egg hatching GO:0009792 34 0.054
Mouse Worm Fly
regulation of myeloid cell differentiation GO:0045637 81 0.054
activation of mapkk activity GO:0000186 18 0.054
anatomical structure homeostasis GO:0060249 100 0.054
response to inorganic substance GO:0010035 127 0.053
positive regulation of cellular amine metabolic process GO:0033240 7 0.053
intracellular receptor signaling pathway GO:0030522 104 0.052
response to temperature stimulus GO:0009266 22 0.052
immunoglobulin secretion GO:0048305 1 0.051
cytokine biosynthetic process GO:0042089 37 0.051
reactive oxygen species metabolic process GO:0072593 75 0.051
Mouse
protein processing GO:0016485 226 0.051
positive regulation of t cell mediated immunity GO:0002711 12 0.050
protein acylation GO:0043543 138 0.050
positive regulation of histone modification GO:0031058 29 0.050
engulfment of apoptotic cell GO:0043652 2 0.050
interleukin 6 biosynthetic process GO:0042226 5 0.050
positive regulation of dendrite morphogenesis GO:0050775 3 0.050
trna wobble uridine modification GO:0002098 3 0.048
regulation of dephosphorylation GO:0035303 96 0.048
regulation of cysteine type endopeptidase activity GO:2000116 127 0.048
response to heat GO:0009408 21 0.048
mitotic nuclear division GO:0007067 119 0.047
cation transport GO:0006812 331 0.046
production of molecular mediator of immune response GO:0002440 37 0.045
rna processing GO:0006396 255 0.045
interleukin 2 production GO:0032623 20 0.045
cell adhesion GO:0007155 325 0.045
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 4 0.044
cellular amino acid metabolic process GO:0006520 116 0.044
establishment of protein localization to membrane GO:0090150 121 0.043
regulation of ras protein signal transduction GO:0046578 155 0.043
protein localization to membrane GO:0072657 160 0.043
positive regulation of proteolysis GO:0045862 142 0.043
defense response to other organism GO:0098542 129 0.043
Fly
positive regulation of locomotion GO:0040017 186 0.042
negative regulation of proteolysis GO:0045861 132 0.042
positive regulation of leukocyte differentiation GO:1902107 37 0.042
regulation of mitotic cell cycle GO:0007346 189 0.042
regulation of cellular amino acid metabolic process GO:0006521 6 0.041
negative regulation of protein transport GO:0051224 75 0.041
cellular lipid metabolic process GO:0044255 303 0.041
hemopoiesis GO:0030097 180 0.041
sterol transport GO:0015918 39 0.041
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.040
negative regulation of protein kinase activity GO:0006469 98 0.040
cilium assembly GO:0042384 63 0.038
rna interference GO:0016246 4 0.038
regulation of translational initiation GO:0006446 24 0.038
cell projection organization GO:0030030 252 0.038
cellular response to interleukin 1 GO:0071347 35 0.038
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.037
membrane organization GO:0061024 292 0.037
regulation of growth GO:0040008 165 0.036
response to light stimulus GO:0009416 87 0.036
muscle cell proliferation GO:0033002 35 0.036
cell morphogenesis GO:0000902 296 0.036
synaptic transmission GO:0007268 61 0.036
innate immune response activating signal transduction GO:0002758 48 0.036
regulation of intracellular transport GO:0032386 195 0.036
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 4 0.035
prostaglandin secretion GO:0032310 2 0.035
receptor mediated endocytosis GO:0006898 84 0.035
morphogenesis of embryonic epithelium GO:0016331 4 0.035
Mouse Fly
response to metal ion GO:0010038 84 0.035
nucleoside triphosphate catabolic process GO:0009143 394 0.035
regulation of system process GO:0044057 101 0.034
regulation of phosphatase activity GO:0010921 81 0.033
cellular component assembly involved in morphogenesis GO:0010927 73 0.033
t cell activation GO:0042110 99 0.033
myosin filament assembly GO:0031034 2 0.032
peptidyl lysine modification GO:0018205 144 0.032
positive regulation of mitotic cell cycle GO:0045931 60 0.032
reproduction GO:0000003 63 0.032
chemical homeostasis GO:0048878 306 0.032
mrna metabolic process GO:0016071 175 0.031
endomembrane system organization GO:0010256 196 0.031
cellular response to external stimulus GO:0071496 111 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.031
cell fate commitment involved in formation of primary germ layer GO:0060795 6 0.031
Worm
positive regulation of myeloid cell differentiation GO:0045639 39 0.031
activation of immune response GO:0002253 114 0.031
primary neural tube formation GO:0014020 3 0.030
neuron death GO:0070997 65 0.030
nucleocytoplasmic transport GO:0006913 176 0.030
peptidyl tyrosine modification GO:0018212 170 0.029
interleukin 6 production GO:0032635 37 0.029
gland development GO:0048732 48 0.029
lipid localization GO:0010876 106 0.029
positive regulation of peptidase activity GO:0010952 88 0.029
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.029
t cell mediated immunity GO:0002456 25 0.029
myeloid dendritic cell activation GO:0001773 4 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.029
regulation of lymphocyte mediated immunity GO:0002706 33 0.028
positive regulation of endopeptidase activity GO:0010950 84 0.028
pattern recognition receptor signaling pathway GO:0002221 48 0.028
protein polyubiquitination GO:0000209 110 0.028
regulation of response to wounding GO:1903034 101 0.028
negative regulation of organelle organization GO:0010639 126 0.027
positive regulation of chromosome organization GO:2001252 41 0.027
protein autoubiquitination GO:0051865 37 0.027
microtubule based movement GO:0007018 32 0.027
establishment of protein localization to organelle GO:0072594 172 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
adaptive immune response GO:0002250 49 0.027
embryonic morphogenesis GO:0048598 85 0.026
Mouse Worm Fly
neuron apoptotic process GO:0051402 39 0.026
neurological system process GO:0050877 163 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.026
dna integrity checkpoint GO:0031570 71 0.026
regulation of mitotic cell cycle phase transition GO:1901990 118 0.026
organelle assembly GO:0070925 176 0.026
endocytic recycling GO:0032456 12 0.026
protein import into nucleus GO:0006606 104 0.026
transmembrane transport GO:0055085 399 0.026
regulation of chromatin organization GO:1902275 56 0.026
negative regulation of multi organism process GO:0043901 92 0.026
nuclear export GO:0051168 69 0.025
cell fate determination GO:0001709 3 0.025
Worm
negative regulation of protein localization to nucleus GO:1900181 34 0.025
nuclear division GO:0000280 128 0.025
meiosis i GO:0007127 4 0.025
regulation of membrane potential GO:0042391 95 0.025
cellular response to hydrogen peroxide GO:0070301 37 0.025
multicellular organismal movement GO:0050879 17 0.025
mitotic cell cycle checkpoint GO:0007093 68 0.025
mrna processing GO:0006397 133 0.025
regulation of cell cycle process GO:0010564 266 0.024
neurotransmitter transport GO:0006836 10 0.024
jun phosphorylation GO:0007258 28 0.024
regulation of histone modification GO:0031056 47 0.024
negative regulation of cytoskeleton organization GO:0051494 45 0.024
activation of innate immune response GO:0002218 55 0.024
biological adhesion GO:0022610 331 0.024
positive regulation of lymphocyte activation GO:0051251 73 0.024
cellular response to nitrogen compound GO:1901699 144 0.023
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.023
negative regulation of wnt signaling pathway GO:0030178 69 0.023
response to lipopolysaccharide GO:0032496 70 0.023
Fly
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.023
cellular response to heat GO:0034605 14 0.023
reproductive process GO:0022414 106 0.023
regulation of nucleotide metabolic process GO:0006140 269 0.023
immune response activating signal transduction GO:0002757 90 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
lung alveolus development GO:0048286 4 0.022
methylation GO:0032259 106 0.022
plasma membrane organization GO:0007009 115 0.022
negative regulation of cell cycle process GO:0010948 121 0.022
positive regulation of cellular protein catabolic process GO:1903364 37 0.022
meiotic chromosome segregation GO:0045132 4 0.022
positive regulation of growth GO:0045927 58 0.022
positive regulation of neuron projection development GO:0010976 34 0.022
somitogenesis GO:0001756 2 0.021
negative regulation of endopeptidase activity GO:0010951 84 0.021
regulation of chromatin modification GO:1903308 51 0.021
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.021
positive regulation of interleukin 6 production GO:0032755 21 0.021
activation of nf kappab inducing kinase activity GO:0007250 9 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.021
negative regulation of immune system process GO:0002683 136 0.021
signal release GO:0023061 70 0.021
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.021
lymphocyte mediated immunity GO:0002449 48 0.020
reproductive system development GO:0061458 56 0.020
cell fate specification GO:0001708 8 0.020
Worm
ribonucleotide catabolic process GO:0009261 405 0.020
dna dependent dna replication GO:0006261 44 0.020
regulation of translation GO:0006417 89 0.020
organophosphate catabolic process GO:0046434 430 0.020
negative regulation of binding GO:0051100 57 0.020
positive regulation of neuron differentiation GO:0045666 40 0.020
regulation of protein stability GO:0031647 87 0.020
response to interleukin 1 GO:0070555 47 0.020
wound healing GO:0042060 115 0.020
negative regulation of apoptotic signaling pathway GO:2001234 97 0.020
Mouse
cellular response to abiotic stimulus GO:0071214 117 0.019
actin mediated cell contraction GO:0070252 12 0.019
axonogenesis GO:0007409 31 0.019

MAP3K7 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.059
connective tissue disease DOID:65 109 0.059
disease of mental health DOID:150 70 0.052
cognitive disorder DOID:1561 29 0.052
integumentary system disease DOID:16 43 0.033
skin disease DOID:37 33 0.030