Homo sapiens

22 known processes

IDH1

isocitrate dehydrogenase 1 (NADP+), soluble

(Aliases: IDPC,PICD,IDCD,IDP,IDH)

IDH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic hydroxy compound metabolic process GO:1901615 147 0.558
alcohol metabolic process GO:0006066 114 0.503
small molecule biosynthetic process GO:0044283 157 0.428
lipid metabolic process GO:0006629 381 0.414
sulfur compound metabolic process GO:0006790 101 0.361
Mouse
lipid biosynthetic process GO:0008610 177 0.352
negative regulation of icosanoid secretion GO:0032304 2 0.350
oxidation reduction process GO:0055114 396 0.335
steroid metabolic process GO:0008202 94 0.293
small molecule catabolic process GO:0044282 92 0.283
monocarboxylic acid metabolic process GO:0032787 185 0.278
cellular lipid metabolic process GO:0044255 303 0.245
organic acid catabolic process GO:0016054 71 0.235
lipid modification GO:0030258 84 0.218
lipid oxidation GO:0034440 33 0.205
cofactor metabolic process GO:0051186 87 0.201
diterpenoid metabolic process GO:0016101 20 0.175
cellular lipid catabolic process GO:0044242 65 0.147
determination of adult lifespan GO:0008340 2 0.137
Worm
monocarboxylic acid biosynthetic process GO:0072330 67 0.123
post embryonic development GO:0009791 2 0.119
carboxylic acid catabolic process GO:0046395 71 0.118
lipid catabolic process GO:0016042 84 0.112
membrane organization GO:0061024 292 0.103
fatty acid catabolic process GO:0009062 29 0.098
amine metabolic process GO:0009308 44 0.094
protein homooligomerization GO:0051260 100 0.094
organic hydroxy compound biosynthetic process GO:1901617 71 0.086
monocarboxylic acid catabolic process GO:0072329 37 0.085
organic anion transport GO:0015711 103 0.079
cellular amino acid metabolic process GO:0006520 116 0.078
Mouse
response to biotic stimulus GO:0009607 276 0.075
multicellular organismal aging GO:0010259 3 0.074
Worm
terpenoid metabolic process GO:0006721 27 0.073
coenzyme metabolic process GO:0006732 65 0.073
organic acid biosynthetic process GO:0016053 97 0.069
primary alcohol metabolic process GO:0034308 17 0.068
negative regulation of catalytic activity GO:0043086 335 0.067
cellular amine metabolic process GO:0044106 41 0.065
defense response GO:0006952 315 0.062
cellular ketone metabolic process GO:0042180 80 0.062
response to external biotic stimulus GO:0043207 261 0.060
maintenance of location GO:0051235 112 0.059
response to bacterium GO:0009617 144 0.057
cellular hormone metabolic process GO:0034754 41 0.054
response to lipid GO:0033993 206 0.054
Rat
carbohydrate metabolic process GO:0005975 207 0.051
steroid biosynthetic process GO:0006694 46 0.051
innate immune response GO:0045087 178 0.049
lipid localization GO:0010876 106 0.049
organophosphate biosynthetic process GO:0090407 163 0.047
fatty acid metabolic process GO:0006631 115 0.047
protein oligomerization GO:0051259 173 0.046
carboxylic acid biosynthetic process GO:0046394 97 0.044
single organism membrane organization GO:0044802 268 0.041
associative learning GO:0008306 1 0.041
endomembrane system organization GO:0010256 196 0.040
anion transport GO:0006820 161 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.039
female gamete generation GO:0007292 2 0.037
fatty acid oxidation GO:0019395 31 0.037
positive regulation of transport GO:0051050 336 0.036
regulation of hormone levels GO:0010817 125 0.035
regulation of proteolysis GO:0030162 293 0.035
long chain fatty acid metabolic process GO:0001676 30 0.035
alcohol biosynthetic process GO:0046165 52 0.035
glycerolipid metabolic process GO:0046486 107 0.034
organonitrogen compound biosynthetic process GO:1901566 200 0.034
negative regulation of protein metabolic process GO:0051248 391 0.034
protein homotetramerization GO:0051289 28 0.034
single organism cellular localization GO:1902580 332 0.033
very long chain fatty acid metabolic process GO:0000038 19 0.033
response to light stimulus GO:0009416 87 0.032
osteoblast differentiation GO:0001649 92 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.032
vesicle mediated transport GO:0016192 371 0.032
cellular modified amino acid metabolic process GO:0006575 64 0.030
Mouse
ossification GO:0001503 121 0.029
response to other organism GO:0051707 261 0.029
cellular biogenic amine metabolic process GO:0006576 34 0.029
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
monosaccharide metabolic process GO:0005996 74 0.028
regulation of transferase activity GO:0051338 355 0.028
oogenesis GO:0048477 2 0.028
negative regulation of transport GO:0051051 176 0.028
protein maturation GO:0051604 233 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
blastoderm segmentation GO:0007350 2 0.027
immune response GO:0006955 307 0.026
acylglycerol metabolic process GO:0006639 27 0.026
ketone biosynthetic process GO:0042181 17 0.026
fatty acid beta oxidation GO:0006635 22 0.025
response to organic cyclic compound GO:0014070 204 0.025
Rat
peroxisome organization GO:0007031 28 0.024
purine containing compound catabolic process GO:0072523 411 0.024
immune system development GO:0002520 195 0.023
glycerolipid biosynthetic process GO:0045017 51 0.023
reactive oxygen species metabolic process GO:0072593 75 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.023
regulation of kinase activity GO:0043549 314 0.023
regulation of intracellular transport GO:0032386 195 0.023
hormone metabolic process GO:0042445 61 0.023
secretion by cell GO:0032940 226 0.022
lipid storage GO:0019915 28 0.022
regulation of secretion GO:0051046 194 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
endosomal transport GO:0016197 129 0.022
glycerophospholipid metabolic process GO:0006650 84 0.022
neurological system process GO:0050877 163 0.022
secretion GO:0046903 254 0.021
protein processing GO:0016485 226 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
response to steroid hormone GO:0048545 80 0.020
Rat
fatty acid biosynthetic process GO:0006633 46 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
regulation of synaptic plasticity GO:0048167 3 0.020
sterol metabolic process GO:0016125 28 0.020
defense response to other organism GO:0098542 129 0.020
acyl coa metabolic process GO:0006637 23 0.020
segmentation GO:0035282 4 0.020
nucleoside phosphate biosynthetic process GO:1901293 109 0.020
response to oxygen containing compound GO:1901700 369 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
visual learning GO:0008542 1 0.019
negative regulation of protein modification process GO:0031400 200 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
protein tetramerization GO:0051262 47 0.019
cytoplasmic transport GO:0016482 379 0.019
positive regulation of lipid biosynthetic process GO:0046889 22 0.019
carboxylic acid transport GO:0046942 63 0.019
regulation of peptidase activity GO:0052547 180 0.019
response to abiotic stimulus GO:0009628 336 0.019
negative regulation of protein processing GO:0010955 142 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
golgi vesicle transport GO:0048193 80 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
endocytosis GO:0006897 159 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
positive regulation of secretion GO:0051047 116 0.018
sphingolipid metabolic process GO:0006665 38 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
growth GO:0040007 202 0.018
response to extracellular stimulus GO:0009991 85 0.018
neuromuscular junction development GO:0007528 3 0.018
regulation of protein kinase activity GO:0045859 289 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
regulation of immune response GO:0050776 201 0.017
isoprenoid metabolic process GO:0006720 39 0.017
protein localization to membrane GO:0072657 160 0.017
engulfment of apoptotic cell GO:0043652 2 0.017
positive regulation of intracellular transport GO:0032388 104 0.017
response to hormone GO:0009725 175 0.016
Rat
negative regulation of kinase activity GO:0033673 106 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
negative regulation of transferase activity GO:0051348 124 0.016
defense response to bacterium GO:0042742 63 0.016
oocyte development GO:0048599 1 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
system process GO:0003008 349 0.016
organic acid transport GO:0015849 65 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
regulation of lipid metabolic process GO:0019216 96 0.016
hexose metabolic process GO:0019318 55 0.016
negative regulation of protein maturation GO:1903318 142 0.016
regulation of lipid transport GO:0032368 44 0.016
locomotory behavior GO:0007626 1 0.016
aging GO:0007568 66 0.016
Worm
regulation of cell cycle GO:0051726 393 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
regulation of growth GO:0040008 165 0.015
polyol metabolic process GO:0019751 32 0.015
oocyte differentiation GO:0009994 2 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
apoptotic signaling pathway GO:0097190 268 0.015
regulation of protein localization GO:0032880 296 0.015
regulation of protein maturation GO:1903317 150 0.015
regulation of multi organism process GO:0043900 157 0.015
anterior posterior axis specification GO:0009948 2 0.014
positive regulation of catabolic process GO:0009896 310 0.014
cellular homeostasis GO:0019725 196 0.014
response to nutrient levels GO:0031667 81 0.014
ion transmembrane transport GO:0034220 338 0.014
positive regulation of immune system process GO:0002684 283 0.014
c21 steroid hormone metabolic process GO:0008207 17 0.014
male gonad development GO:0008584 23 0.014
triglyceride metabolic process GO:0006641 23 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
regulation of protein processing GO:0070613 150 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
regulation of response to external stimulus GO:0032101 222 0.014
dicarboxylic acid metabolic process GO:0043648 29 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
positive regulation of growth GO:0045927 58 0.014
tripartite regional subdivision GO:0007351 2 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
transmembrane transport GO:0055085 399 0.013
hemopoiesis GO:0030097 180 0.013
regulation of cell growth GO:0001558 135 0.013
spermatid development GO:0007286 4 0.013
positive regulation of lipid metabolic process GO:0045834 50 0.013
regulation of mapk cascade GO:0043408 262 0.013
spermatid differentiation GO:0048515 4 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
reproductive process GO:0022414 106 0.013
Rat
cytokine production GO:0001816 247 0.013
organophosphate catabolic process GO:0046434 430 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
cholesterol metabolic process GO:0008203 28 0.013
membrane lipid metabolic process GO:0006643 53 0.013
negative regulation of proteolysis GO:0045861 132 0.013
cofactor biosynthetic process GO:0051188 31 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
peripheral nervous system development GO:0007422 2 0.013
glutathione metabolic process GO:0006749 20 0.013
Mouse
regulation of cellular response to stress GO:0080135 244 0.013
negative regulation of phosphorylation GO:0042326 174 0.012
cell projection organization GO:0030030 252 0.012
chemical homeostasis GO:0048878 306 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
memory GO:0007613 3 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
positive regulation of developmental process GO:0051094 314 0.012
male sex differentiation GO:0046661 25 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
cell growth GO:0016049 160 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
negative regulation of cell death GO:0060548 345 0.012
epithelium development GO:0060429 227 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
regulation of cell cycle process GO:0010564 266 0.012
phospholipid metabolic process GO:0006644 99 0.012
lipid transport GO:0006869 90 0.012
inner ear morphogenesis GO:0042472 4 0.012
regeneration GO:0031099 4 0.012
central nervous system development GO:0007417 123 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
regulation of protein transport GO:0051223 213 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
epithelial cell differentiation GO:0030855 141 0.012
terpenoid biosynthetic process GO:0016114 2 0.012
plasma membrane organization GO:0007009 115 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.011
single organism reproductive process GO:0044702 98 0.011
Rat
positive regulation of cell differentiation GO:0045597 211 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
actin filament based process GO:0030029 224 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
unsaturated fatty acid metabolic process GO:0033559 37 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
mitotic cell cycle process GO:1903047 286 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
response to inorganic substance GO:0010035 127 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
regulation of secretion by cell GO:1903530 177 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
head development GO:0060322 108 0.011
reproductive system development GO:0061458 56 0.011
Rat
immune effector process GO:0002252 159 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
regulation of defense response GO:0031347 154 0.011
positive regulation of proteolysis GO:0045862 142 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
protein catabolic process GO:0030163 325 0.011
long chain fatty acid import GO:0044539 5 0.010
cellular chemical homeostasis GO:0055082 180 0.010
organophosphate ester transport GO:0015748 32 0.010
cholesterol transport GO:0030301 39 0.010
cellular response to dna damage stimulus GO:0006974 379 0.010
regulation of locomotion GO:0040012 329 0.010
protein localization to plasma membrane GO:0072659 93 0.010
response to starvation GO:0042594 59 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
alpha amino acid metabolic process GO:1901605 72 0.010
skin development GO:0043588 76 0.010
adult locomotory behavior GO:0008344 1 0.010
nucleoside catabolic process GO:0009164 408 0.010
cation transmembrane transport GO:0098655 238 0.010
sulfur compound biosynthetic process GO:0044272 38 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
regulation of cell maturation GO:1903429 3 0.010
cell morphogenesis GO:0000902 296 0.010
carbohydrate catabolic process GO:0016052 36 0.010
positive regulation of secretion by cell GO:1903532 108 0.010
nucleotide catabolic process GO:0009166 408 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
positive regulation of endopeptidase activity GO:0010950 84 0.010
positive regulation of apoptotic process GO:0043065 246 0.010
biological adhesion GO:0022610 331 0.010
interspecies interaction between organisms GO:0044419 156 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
generation of precursor metabolites and energy GO:0006091 68 0.010

IDH1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.240
Human
inherited metabolic disorder DOID:655 242 0.104
Human
immune system disease DOID:2914 155 0.046
amino acid metabolic disorder DOID:9252 50 0.029
Human
central nervous system disease DOID:331 186 0.024
nervous system disease DOID:863 431 0.024
disease of cellular proliferation DOID:14566 174 0.015
cancer DOID:162 167 0.014
organ system cancer DOID:0050686 164 0.014
musculoskeletal system disease DOID:17 223 0.012
sensory system disease DOID:0050155 203 0.011
carbohydrate metabolic disorder DOID:2978 55 0.011
brain disease DOID:936 73 0.010
cell type cancer DOID:0050687 10 0.001
malignant glioma DOID:3070 3 0.000