Homo sapiens

0 known processes

SH2D2A

SH2 domain containing 2A

(Aliases: SCAP,F2771,TSAD,VRAP)

SH2D2A biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
leukocyte activation GO:0045321 164 0.515
t cell activation GO:0042110 99 0.323
lymphocyte activation GO:0046649 133 0.310
regulation of cellular amine metabolic process GO:0033238 11 0.250
peptidyl tyrosine phosphorylation GO:0018108 170 0.239
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.202
regulation of mapk cascade GO:0043408 262 0.201
regulation of cellular amino acid metabolic process GO:0006521 6 0.197
cytoplasmic transport GO:0016482 379 0.193
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.192
regulation of t cell activation GO:0050863 77 0.179
regulation of transferase activity GO:0051338 355 0.173
regulation of immune response GO:0050776 201 0.171
immune response GO:0006955 307 0.162
amine metabolic process GO:0009308 44 0.161
signal transduction by phosphorylation GO:0023014 297 0.158
positive regulation of cell proliferation GO:0008284 301 0.156
regulation of lymphocyte activation GO:0051249 103 0.152
gamma delta t cell activation GO:0046629 3 0.151
positive regulation of gamma delta t cell activation GO:0046645 1 0.145
negative regulation of transport GO:0051051 176 0.144
cytokine mediated signaling pathway GO:0019221 109 0.144
positive thymic t cell selection GO:0045059 1 0.144
cell activation GO:0001775 213 0.135
positive regulation of immune system process GO:0002684 283 0.135
peptidyl tyrosine modification GO:0018212 170 0.133
positive regulation of cell motility GO:2000147 177 0.132
cellular amino acid metabolic process GO:0006520 116 0.132
positive regulation of immune response GO:0050778 159 0.130
regulation of cellular ketone metabolic process GO:0010565 50 0.126
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.124
positive regulation of phosphorylation GO:0042327 394 0.123
negative regulation of cell death GO:0060548 345 0.120
regulation of cellular component movement GO:0051270 334 0.120
negative regulation of programmed cell death GO:0043069 321 0.114
antigen receptor mediated signaling pathway GO:0050851 38 0.106
enzyme linked receptor protein signaling pathway GO:0007167 303 0.105
positive regulation of apoptotic process GO:0043065 246 0.104
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.104
biological adhesion GO:0022610 331 0.102
motor neuron axon guidance GO:0008045 2 0.102
regulation of cell motility GO:2000145 299 0.098
immune response activating signal transduction GO:0002757 90 0.097
defense response GO:0006952 315 0.097
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.096
regulation of protein localization GO:0032880 296 0.094
positive regulation of cellular amine metabolic process GO:0033240 7 0.093
regulation of mononuclear cell proliferation GO:0032944 65 0.092
negative regulation of phosphate metabolic process GO:0045936 267 0.092
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.090
regulation of cytokine production GO:0001817 232 0.087
ion homeostasis GO:0050801 230 0.086
negative regulation of catalytic activity GO:0043086 335 0.084
Human
positive regulation of kinase activity GO:0033674 204 0.083
regulation of protein kinase activity GO:0045859 289 0.083
peptide transport GO:0015833 74 0.083
chemical homeostasis GO:0048878 306 0.081
calcium ion transport GO:0006816 147 0.081
segmentation GO:0035282 4 0.080
activation of immune response GO:0002253 114 0.080
regulation of locomotion GO:0040012 329 0.079
lipid transport GO:0006869 90 0.079
calcium ion homeostasis GO:0055074 122 0.079
positive regulation of protein phosphorylation GO:0001934 313 0.078
negative regulation of cellular protein metabolic process GO:0032269 353 0.077
lipid modification GO:0030258 84 0.075
negative regulation of protein metabolic process GO:0051248 391 0.074
single organism cellular localization GO:1902580 332 0.073
mapk cascade GO:0000165 288 0.072
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.072
cellular chemical homeostasis GO:0055082 180 0.071
positive regulation of mapk cascade GO:0043410 190 0.071
positive regulation of protein kinase activity GO:0045860 190 0.070
leukocyte mediated immunity GO:0002443 59 0.070
circulatory system development GO:0072359 262 0.068
intracellular protein transport GO:0006886 270 0.068
positive regulation of cytokine production GO:0001819 167 0.068
protein modification by small protein conjugation GO:0032446 342 0.066
single organismal cell cell adhesion GO:0016337 148 0.066
positive regulation of alpha beta t cell proliferation GO:0046641 5 0.066
calcium mediated signaling GO:0019722 44 0.065
metal ion transport GO:0030001 272 0.065
mitotic cell cycle process GO:1903047 286 0.064
response to cytokine GO:0034097 232 0.064
cellular ketone metabolic process GO:0042180 80 0.063
single organism membrane organization GO:0044802 268 0.062
system process GO:0003008 349 0.062
regulation of cell migration GO:0030334 289 0.062
cytokine production GO:0001816 247 0.061
response to other organism GO:0051707 261 0.061
cellular amine metabolic process GO:0044106 41 0.059
leukocyte differentiation GO:0002521 98 0.059
positive regulation of transferase activity GO:0051347 227 0.058
regulation of establishment of protein localization GO:0070201 242 0.058
regulation of protein transport GO:0051223 213 0.058
negative regulation of apoptotic process GO:0043066 316 0.057
lymphocyte proliferation GO:0046651 70 0.057
protein import GO:0017038 130 0.057
regulation of b cell receptor signaling pathway GO:0050855 4 0.057
response to biotic stimulus GO:0009607 276 0.056
regulation of kinase activity GO:0043549 314 0.056
cellular response to endogenous stimulus GO:0071495 336 0.056
t cell selection GO:0045058 4 0.055
hemopoiesis GO:0030097 180 0.055
erk1 and erk2 cascade GO:0070371 104 0.054
apoptotic signaling pathway GO:0097190 268 0.054
positive regulation of leukocyte activation GO:0002696 80 0.052
cellular response to growth factor stimulus GO:0071363 197 0.052
regulation of leukocyte activation GO:0002694 115 0.052
cellular macromolecule catabolic process GO:0044265 380 0.052
positive regulation of lymphocyte proliferation GO:0050671 46 0.052
divalent metal ion transport GO:0070838 152 0.052
regulation of ion homeostasis GO:2000021 73 0.052
regulation of protein serine threonine kinase activity GO:0071900 179 0.051
epithelial cell proliferation GO:0050673 128 0.051
release of sequestered calcium ion into cytosol GO:0051209 41 0.051
cardiovascular system development GO:0072358 262 0.051
protein catabolic process GO:0030163 325 0.051
negative regulation of cellular component movement GO:0051271 106 0.051
membrane organization GO:0061024 292 0.050
protein ubiquitination GO:0016567 314 0.050
regulation of secretion GO:0051046 194 0.049
positive regulation of leukocyte proliferation GO:0070665 48 0.049
mononuclear cell proliferation GO:0032943 71 0.049
protein dephosphorylation GO:0006470 81 0.049
regulation of peptidase activity GO:0052547 180 0.049
regulation of anatomical structure morphogenesis GO:0022603 286 0.048
cellular response to dna damage stimulus GO:0006974 379 0.048
regulation of intracellular transport GO:0032386 195 0.048
divalent inorganic cation homeostasis GO:0072507 136 0.048
secretion by cell GO:0032940 226 0.048
protein autophosphorylation GO:0046777 123 0.048
regeneration GO:0031099 4 0.048
protein maturation GO:0051604 233 0.048
regulation of cell cycle GO:0051726 393 0.047
regulation of cell adhesion GO:0030155 166 0.047
divalent inorganic cation transport GO:0072511 158 0.047
mitotic cell cycle GO:0000278 326 0.047
immune system development GO:0002520 195 0.047
regulation of cell growth GO:0001558 135 0.046
positive regulation of transport GO:0051050 336 0.046
positive regulation of cellular component movement GO:0051272 181 0.045
regulation of ion transmembrane transport GO:0034765 132 0.045
glycosyl compound catabolic process GO:1901658 413 0.045
positive regulation of locomotion GO:0040017 186 0.045
positive regulation of alpha beta t cell activation GO:0046635 10 0.045
dephosphorylation GO:0016311 209 0.045
Human
regulation of secretion by cell GO:1903530 177 0.044
positive regulation of organelle organization GO:0010638 195 0.044
extrinsic apoptotic signaling pathway GO:0097191 119 0.044
lymphocyte mediated immunity GO:0002449 48 0.044
muscle system process GO:0003012 81 0.044
negative regulation of phosphorylation GO:0042326 174 0.044
reactive nitrogen species metabolic process GO:2001057 3 0.043
cellular component morphogenesis GO:0032989 314 0.043
growth GO:0040007 202 0.043
metal ion homeostasis GO:0055065 169 0.043
transmembrane transport GO:0055085 399 0.043
regulation of cytoplasmic transport GO:1903649 149 0.043
positive regulation of catabolic process GO:0009896 310 0.042
regulation of lymphocyte proliferation GO:0050670 64 0.042
monosaccharide metabolic process GO:0005996 74 0.042
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.042
epithelium migration GO:0090132 119 0.042
response to external biotic stimulus GO:0043207 261 0.042
carbohydrate metabolic process GO:0005975 207 0.042
positive regulation of ion transport GO:0043270 87 0.042
establishment of protein localization to plasma membrane GO:0090002 68 0.041
organ morphogenesis GO:0009887 147 0.041
i kappab kinase nf kappab signaling GO:0007249 166 0.041
positive regulation of cell death GO:0010942 263 0.040
lipid biosynthetic process GO:0008610 177 0.040
sequestering of calcium ion GO:0051208 17 0.040
regulation of leukocyte proliferation GO:0070663 67 0.039
regulation of sequestering of calcium ion GO:0051282 41 0.039
establishment of protein localization to organelle GO:0072594 172 0.039
cell cycle phase transition GO:0044770 173 0.039
negative regulation of proteolysis GO:0045861 132 0.039
cell adhesion GO:0007155 325 0.039
actin filament based process GO:0030029 224 0.039
negative regulation of protein modification process GO:0031400 200 0.039
single organism nuclear import GO:1902593 104 0.039
regulation of hormone levels GO:0010817 125 0.038
negative regulation of intracellular signal transduction GO:1902532 183 0.038
regulation of cell differentiation GO:0045595 393 0.038
response to abiotic stimulus GO:0009628 336 0.038
regulation of cell activation GO:0050865 125 0.038
negative regulation of kinase activity GO:0033673 106 0.038
maintenance of location GO:0051235 112 0.038
regulation of platelet aggregation GO:0090330 4 0.038
cellular metal ion homeostasis GO:0006875 146 0.037
regulation of immune effector process GO:0002697 91 0.037
regulation of gamma delta t cell activation GO:0046643 1 0.037
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.037
cellular ion homeostasis GO:0006873 168 0.036
female gamete generation GO:0007292 2 0.036
hematopoietic or lymphoid organ development GO:0048534 186 0.036
cation homeostasis GO:0055080 189 0.036
regulation of leukocyte differentiation GO:1902105 61 0.036
negative regulation of immune system process GO:0002683 136 0.036
cell projection organization GO:0030030 252 0.036
sequestering of metal ion GO:0051238 24 0.035
protein targeting GO:0006605 187 0.035
hormone metabolic process GO:0042445 61 0.035
response to virus GO:0009615 126 0.035
nuclear import GO:0051170 106 0.035
negative regulation of protein phosphorylation GO:0001933 140 0.035
protein import into nucleus GO:0006606 104 0.034
cell killing GO:0001906 34 0.034
positive regulation of cellular component biogenesis GO:0044089 158 0.034
regulation of cytokine mediated signaling pathway GO:0001959 41 0.034
immune response regulating signaling pathway GO:0002764 97 0.034
tripartite regional subdivision GO:0007351 2 0.034
tissue regeneration GO:0042246 3 0.034
neuromuscular junction development GO:0007528 3 0.034
cellular homeostasis GO:0019725 196 0.034
regulation of protein ubiquitination GO:0031396 95 0.034
positive regulation of lymphocyte activation GO:0051251 73 0.033
negative regulation of homeostatic process GO:0032845 59 0.033
muscle contraction GO:0006936 73 0.033
cellular lipid metabolic process GO:0044255 303 0.033
organic anion transport GO:0015711 103 0.033
organonitrogen compound biosynthetic process GO:1901566 200 0.033
regulation of protein processing GO:0070613 150 0.033
t cell differentiation in thymus GO:0033077 4 0.033
regulation of t cell receptor signaling pathway GO:0050856 7 0.033
nucleocytoplasmic transport GO:0006913 176 0.033
microtubule based process GO:0007017 210 0.033
lipid metabolic process GO:0006629 381 0.033
g protein coupled receptor signaling pathway GO:0007186 207 0.033
negative regulation of protein kinase activity GO:0006469 98 0.033
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.032
regulation of b cell activation GO:0050864 24 0.032
angiogenesis GO:0001525 147 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
Human
associative learning GO:0008306 1 0.032
cation transport GO:0006812 331 0.032
actin filament organization GO:0007015 128 0.032
regulation of nucleocytoplasmic transport GO:0046822 98 0.032
negative regulation of protein maturation GO:1903318 142 0.032
regulation of oxidoreductase activity GO:0051341 43 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.031
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.031
blastoderm segmentation GO:0007350 2 0.031
cellular protein catabolic process GO:0044257 261 0.031
cell development GO:0048468 328 0.031
ribonucleoside catabolic process GO:0042454 406 0.031
neuron differentiation GO:0030182 138 0.031
t cell differentiation GO:0030217 29 0.031
regulation of ion transport GO:0043269 189 0.031
protein localization to organelle GO:0033365 280 0.030
microtubule cytoskeleton organization GO:0000226 176 0.030
positive regulation of secretion GO:0051047 116 0.030
protein processing GO:0016485 226 0.030
regulation of protein complex assembly GO:0043254 147 0.030
regulation of protein import into nucleus GO:0042306 78 0.030
small gtpase mediated signal transduction GO:0007264 78 0.030
endothelial cell proliferation GO:0001935 65 0.030
anterior posterior axis specification GO:0009948 2 0.030
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.029
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.029
endothelial cell migration GO:0043542 86 0.029
fatty acid metabolic process GO:0006631 115 0.029
oocyte development GO:0048599 1 0.029
establishment of protein localization to membrane GO:0090150 121 0.029
t cell receptor signaling pathway GO:0050852 21 0.029
regulation of epithelial cell proliferation GO:0050678 113 0.029
regulation of b cell differentiation GO:0045577 2 0.029
immune effector process GO:0002252 159 0.029
response to growth factor GO:0070848 205 0.029
ribonucleoside triphosphate metabolic process GO:0009199 412 0.028
regulation of antigen receptor mediated signaling pathway GO:0050854 10 0.028
modification dependent macromolecule catabolic process GO:0043632 212 0.028
positive regulation of cell activation GO:0050867 81 0.028
regulation of protein targeting GO:1903533 91 0.028
activation of protein kinase activity GO:0032147 90 0.028
nitrogen compound transport GO:0071705 191 0.028
leukotriene metabolic process GO:0006691 10 0.028
response to radiation GO:0009314 151 0.028
response to light stimulus GO:0009416 87 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.028
positive regulation of protein transport GO:0051222 135 0.028
epithelial cell migration GO:0010631 119 0.028
positive regulation of organic acid transport GO:0032892 3 0.028
cytosolic calcium ion transport GO:0060401 48 0.028
cellular divalent inorganic cation homeostasis GO:0072503 128 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.028
response to lipid GO:0033993 206 0.027
regulation of proteolysis GO:0030162 293 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.027
organophosphate catabolic process GO:0046434 430 0.027
cell type specific apoptotic process GO:0097285 125 0.027
regulation of erk1 and erk2 cascade GO:0070372 99 0.027
regulation of icosanoid secretion GO:0032303 4 0.027
protein localization to plasma membrane GO:0072659 93 0.027
negative regulation of cell motility GO:2000146 104 0.027
regulation of t cell proliferation GO:0042129 42 0.027
positive regulation of cell cycle GO:0045787 140 0.027
post embryonic development GO:0009791 2 0.027
innate immune response GO:0045087 178 0.027
leukocyte apoptotic process GO:0071887 31 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
generation of neurons GO:0048699 152 0.027
reactive oxygen species biosynthetic process GO:1903409 4 0.027
organic hydroxy compound metabolic process GO:1901615 147 0.027
positive regulation of gtp catabolic process GO:0033126 166 0.026
negative regulation of transferase activity GO:0051348 124 0.026
negative regulation of apoptotic signaling pathway GO:2001234 97 0.026
cell cell signaling GO:0007267 155 0.026
regulation of cell projection organization GO:0031344 107 0.026
regulation of dna metabolic process GO:0051052 153 0.026
carboxylic acid transport GO:0046942 63 0.026
cellular calcium ion homeostasis GO:0006874 117 0.026
ion transmembrane transport GO:0034220 338 0.026
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.026
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.026
determination of adult lifespan GO:0008340 2 0.026
transcription factor import into nucleus GO:0042991 40 0.026
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.026
anatomical structure formation involved in morphogenesis GO:0048646 284 0.026
oogenesis GO:0048477 2 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
stress activated mapk cascade GO:0051403 93 0.025
regulation of vasculature development GO:1901342 97 0.025
oxidation reduction process GO:0055114 396 0.025
regulation of response to dna damage stimulus GO:2001020 94 0.025
cannabinoid signaling pathway GO:0038171 2 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.025
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.025
nucleoside triphosphate metabolic process GO:0009141 422 0.025
regulation of cell cycle process GO:0010564 266 0.025
hemostasis GO:0007599 76 0.025
positive regulation of cytoskeleton organization GO:0051495 83 0.025
anterior posterior axis specification embryo GO:0008595 2 0.025
adaptive immune response GO:0002250 49 0.024
cytokine biosynthetic process GO:0042089 37 0.024
vesicle mediated transport GO:0016192 371 0.024
regulation of response to external stimulus GO:0032101 222 0.024
defense response to other organism GO:0098542 129 0.024
protein targeting to nucleus GO:0044744 104 0.024
anion transport GO:0006820 161 0.024
nuclear transport GO:0051169 179 0.024
peptidyl serine modification GO:0018209 106 0.024
lens development in camera type eye GO:0002088 2 0.024
b cell activation GO:0042113 33 0.024
cellular cation homeostasis GO:0030003 163 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
regulation of intracellular protein transport GO:0033157 123 0.024
positive regulation of developmental process GO:0051094 314 0.024
eye photoreceptor cell differentiation GO:0001754 2 0.024
regulation of system process GO:0044057 101 0.024
protein secretion GO:0009306 98 0.024
mitochondrion organization GO:0007005 156 0.023
positive regulation of programmed cell death GO:0043068 249 0.023
thymic t cell selection GO:0045061 2 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
negative regulation of b cell receptor signaling pathway GO:0050859 2 0.023
ras protein signal transduction GO:0007265 73 0.023
single organism cell adhesion GO:0098602 179 0.023
amide transport GO:0042886 76 0.023
cell morphogenesis GO:0000902 296 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.023
small molecule catabolic process GO:0044282 92 0.023
protein localization to membrane GO:0072657 160 0.023
monosaccharide transport GO:0015749 32 0.023
cell growth GO:0016049 160 0.023
positive regulation of mononuclear cell proliferation GO:0032946 47 0.023
response to organic cyclic compound GO:0014070 204 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
positive regulation of antigen receptor mediated signaling pathway GO:0050857 3 0.023
organic acid transport GO:0015849 65 0.023
negative regulation of cell differentiation GO:0045596 171 0.023
regulation of lipid transport GO:0032368 44 0.023
peptidyl tyrosine dephosphorylation GO:0035335 36 0.022
regulation of glial cell proliferation GO:0060251 4 0.022
regulation of protein secretion GO:0050708 86 0.022
neuron projection development GO:0031175 106 0.022
reactive oxygen species metabolic process GO:0072593 75 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.022
regulation of alpha beta t cell activation GO:0046634 13 0.022
regulation of binding GO:0051098 111 0.022
phospholipid metabolic process GO:0006644 99 0.022
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
positive regulation of map kinase activity GO:0043406 80 0.022
mating GO:0007618 1 0.022
dna repair GO:0006281 198 0.022
oocyte differentiation GO:0009994 2 0.022
protein localization to nucleus GO:0034504 136 0.022
regulation of astrocyte chemotaxis GO:2000458 1 0.021
neurogenesis GO:0022008 169 0.021
regulation of epithelial cell migration GO:0010632 93 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
regulation of actin filament length GO:0030832 56 0.021
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 11 0.021
secretion GO:0046903 254 0.021
multi organism cellular process GO:0044764 156 0.021
negative regulation of cell migration GO:0030336 102 0.021
negative regulation of endopeptidase activity GO:0010951 84 0.021
negative regulation of smoothened signaling pathway GO:0045879 3 0.021
purine containing compound catabolic process GO:0072523 411 0.021
multicellular organismal aging GO:0010259 3 0.021
regulation of growth GO:0040008 165 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
embryonic viscerocranium morphogenesis GO:0048703 1 0.021
cell projection assembly GO:0030031 126 0.021
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
carbohydrate transport GO:0008643 37 0.021
plasma membrane organization GO:0007009 115 0.021
cytosolic calcium ion homeostasis GO:0051480 89 0.021
negative regulation of protein processing GO:0010955 142 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
polysaccharide metabolic process GO:0005976 33 0.020
glycogen metabolic process GO:0005977 22 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
regulation of protein localization to plasma membrane GO:1903076 40 0.020
proteasomal protein catabolic process GO:0010498 176 0.020
glycoprotein metabolic process GO:0009100 110 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
carboxylic acid catabolic process GO:0046395 71 0.020
regulation of reactive oxygen species metabolic process GO:2000377 41 0.020
regulation of angiogenesis GO:0045765 92 0.020
positive regulation of t cell activation GO:0050870 54 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
Human
calcium ion transport into cytosol GO:0060402 48 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
actin cytoskeleton organization GO:0030036 207 0.020
epithelium development GO:0060429 227 0.020
regulation of map kinase activity GO:0043405 108 0.020
lymphocyte differentiation GO:0030098 35 0.020
platelet aggregation GO:0070527 32 0.020
modification dependent protein catabolic process GO:0019941 209 0.019
tissue migration GO:0090130 119 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
negative regulation of protein transport GO:0051224 75 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
negative regulation of immune response GO:0050777 40 0.019
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.019
regulation of cellular response to stress GO:0080135 244 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
photoreceptor cell differentiation GO:0046530 2 0.019
positive regulation of interferon gamma production GO:0032729 26 0.019
response to oxygen containing compound GO:1901700 369 0.019
nervous system development GO:0007399 293 0.019
regulation of lipid metabolic process GO:0019216 96 0.019
monocarboxylic acid catabolic process GO:0072329 37 0.019
positive regulation of cell migration GO:0030335 172 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
positive regulation of lymphocyte differentiation GO:0045621 13 0.018
positive regulation of calcium mediated signaling GO:0050850 10 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.018
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.018
t cell proliferation GO:0042098 45 0.018
response to nitrogen compound GO:1901698 184 0.018
melanin metabolic process GO:0006582 1 0.018
positive regulation of gliogenesis GO:0014015 4 0.018
regulation of interleukin 8 production GO:0032677 49 0.018
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.018
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.018
regulation of interferon gamma production GO:0032649 36 0.018
regulation of protein maturation GO:1903317 150 0.018
circadian behavior GO:0048512 2 0.018
taxis GO:0042330 157 0.018
positive regulation of cell growth GO:0030307 48 0.018
positive regulation of intracellular protein transport GO:0090316 76 0.018
brain development GO:0007420 97 0.018
actin mediated cell contraction GO:0070252 12 0.017
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
positive regulation of apoptotic signaling pathway GO:2001235 70 0.017
rab protein signal transduction GO:0032482 4 0.017
regulation of transporter activity GO:0032409 82 0.017
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.017
regulation of transmembrane transport GO:0034762 139 0.017
mrna metabolic process GO:0016071 175 0.017
coagulation GO:0050817 78 0.017
positive regulation of interleukin 4 production GO:0032753 3 0.017
blood vessel development GO:0001568 172 0.017
organic acid catabolic process GO:0016054 71 0.017
regulation of protein localization to nucleus GO:1900180 85 0.017
regulation of cell killing GO:0031341 22 0.017

SH2D2A disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.120
disease of metabolism DOID:0014667 295 0.042
cancer DOID:162 167 0.033
disease of cellular proliferation DOID:14566 174 0.033
organ system cancer DOID:0050686 164 0.026
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
musculoskeletal system disease DOID:17 223 0.018
connective tissue disease DOID:65 109 0.017