Homo sapiens

110 known processes

SETD2

SET domain containing 2

(Aliases: FLJ16420,HIF-1,SET2,FLJ23184,KIAA1732,KMT3A,FLJ46217,HBP231,FLJ22472,FLJ45883,p231HBP,HYPB)

SETD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone modification GO:0016570 251 0.619
chromatin modification GO:0016568 298 0.609
covalent chromatin modification GO:0016569 254 0.463
chromatin organization GO:0006325 351 0.296
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.272
positive regulation of developmental process GO:0051094 314 0.218
cell development GO:0048468 328 0.152
Mouse
histone acetylation GO:0016573 93 0.150
cellular macromolecular complex assembly GO:0034622 324 0.137
cellular response to dna damage stimulus GO:0006974 379 0.126
female gamete generation GO:0007292 2 0.119
tube development GO:0035295 125 0.114
Mouse
negative regulation of chromatin silencing GO:0031936 4 0.113
mrna metabolic process GO:0016071 175 0.113
cellular component morphogenesis GO:0032989 314 0.112
internal protein amino acid acetylation GO:0006475 101 0.110
dna repair GO:0006281 198 0.110
regulation of cellular ketone metabolic process GO:0010565 50 0.104
neural tube formation GO:0001841 3 0.102
Mouse
mitotic cell cycle process GO:1903047 286 0.096
circulatory system development GO:0072359 262 0.096
Mouse
post embryonic development GO:0009791 2 0.094
Fly
mitotic cell cycle GO:0000278 326 0.083
cell division GO:0051301 168 0.073
neuron differentiation GO:0030182 138 0.072
histone lysine methylation GO:0034968 50 0.070
actin filament based process GO:0030029 224 0.070
nervous system development GO:0007399 293 0.066
Mouse
cell morphogenesis GO:0000902 296 0.065
embryo development GO:0009790 123 0.060
Mouse
regulation of cell cycle GO:0051726 393 0.060
chemotaxis GO:0006935 157 0.060
neuron projection development GO:0031175 106 0.059
enzyme linked receptor protein signaling pathway GO:0007167 303 0.057
heart development GO:0007507 95 0.057
Mouse
cellular ketone metabolic process GO:0042180 80 0.056
organelle assembly GO:0070925 176 0.056
nuclear division GO:0000280 128 0.054
protein acylation GO:0043543 138 0.054
neurological system process GO:0050877 163 0.052
central nervous system development GO:0007417 123 0.048
Mouse
mitotic cell cycle phase transition GO:0044772 162 0.046
cell projection organization GO:0030030 252 0.046
chromatin assembly or disassembly GO:0006333 78 0.046
peptidyl lysine acetylation GO:0018394 101 0.045
regulation of cell cycle process GO:0010564 266 0.045
bmp signaling pathway GO:0030509 49 0.045
amine metabolic process GO:0009308 44 0.044
protein deubiquitination GO:0016579 79 0.044
system process GO:0003008 349 0.043
regulation of cell differentiation GO:0045595 393 0.042
regulation of cytoskeleton organization GO:0051493 177 0.042
rna processing GO:0006396 255 0.041
actin cytoskeleton organization GO:0030036 207 0.041
negative regulation of cell differentiation GO:0045596 171 0.041
histone ubiquitination GO:0016574 31 0.040
epithelium development GO:0060429 227 0.040
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.039
Mouse
response to radiation GO:0009314 151 0.039
stem cell development GO:0048864 69 0.038
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.038
growth GO:0040007 202 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
neurogenesis GO:0022008 169 0.037
generation of neurons GO:0048699 152 0.034
taxis GO:0042330 157 0.033
regulation of cell division GO:0051302 116 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
dephosphorylation GO:0016311 209 0.032
cellular amine metabolic process GO:0044106 41 0.032
stem cell differentiation GO:0048863 93 0.032
Mouse
single organism reproductive process GO:0044702 98 0.031
Mouse
organelle fission GO:0048285 149 0.031
histone demethylation GO:0016577 15 0.030
embryonic placenta development GO:0001892 1 0.030
Mouse
cellular protein complex assembly GO:0043623 188 0.030
protein catabolic process GO:0030163 325 0.030
regulation of histone modification GO:0031056 47 0.029
cell morphogenesis involved in differentiation GO:0000904 144 0.029
cell cycle phase transition GO:0044770 173 0.029
anterior posterior axis specification GO:0009948 2 0.028
cell part morphogenesis GO:0032990 137 0.028
protein methylation GO:0006479 74 0.026
ribonucleoprotein complex biogenesis GO:0022613 116 0.026
forelimb morphogenesis GO:0035136 4 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.025
rna splicing GO:0008380 131 0.025
response to abiotic stimulus GO:0009628 336 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
vesicle mediated transport GO:0016192 371 0.024
mitotic cell cycle checkpoint GO:0007093 68 0.023
intracellular protein transport GO:0006886 270 0.023
nucleosome organization GO:0034728 66 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
regulation of growth GO:0040008 165 0.022
morphogenesis of embryonic epithelium GO:0016331 4 0.022
Mouse
protein acetylation GO:0006473 116 0.021
reproductive structure development GO:0048608 55 0.021
Mouse
neuron development GO:0048666 113 0.021
protein modification by small protein removal GO:0070646 92 0.020
compound eye development GO:0048749 1 0.020
regulation of response to dna damage stimulus GO:2001020 94 0.020
reproductive process GO:0022414 106 0.020
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
mrna processing GO:0006397 133 0.020
embryonic morphogenesis GO:0048598 85 0.020
Mouse
determination of adult lifespan GO:0008340 2 0.020
immune response GO:0006955 307 0.020
axon development GO:0061564 34 0.020
chromosome segregation GO:0007059 114 0.019
cellular amino acid metabolic process GO:0006520 116 0.019
microtubule based process GO:0007017 210 0.019
oogenesis GO:0048477 2 0.019
peptidyl lysine modification GO:0018205 144 0.019
protein ubiquitination GO:0016567 314 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
regulation of dna metabolic process GO:0051052 153 0.019
cell projection morphogenesis GO:0048858 129 0.018
post embryonic organ development GO:0048569 1 0.018
viral life cycle GO:0019058 132 0.018
ribonucleoprotein complex subunit organization GO:0071826 81 0.018
behavioral response to ethanol GO:0048149 2 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.018
myosin filament assembly GO:0031034 2 0.018
mitotic nuclear division GO:0007067 119 0.018
regulation of protein localization GO:0032880 296 0.018
negative regulation of apoptotic signaling pathway GO:2001234 97 0.018
positive regulation of programmed cell death GO:0043068 249 0.017
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.017
intracellular receptor signaling pathway GO:0030522 104 0.017
Fly
interspecies interaction between organisms GO:0044419 156 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
reproductive system development GO:0061458 56 0.017
Mouse
histone methylation GO:0016571 60 0.017
cytoplasmic transport GO:0016482 379 0.017
apoptotic signaling pathway GO:0097190 268 0.016
segmentation GO:0035282 4 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
regulation of multi organism process GO:0043900 157 0.016
viral process GO:0016032 146 0.016
regulation of chromatin modification GO:1903308 51 0.016
cytokinesis GO:0000910 96 0.016
protein autophosphorylation GO:0046777 123 0.016
regulation of dephosphorylation GO:0035303 96 0.016
hemopoiesis GO:0030097 180 0.016
dna templated transcription initiation GO:0006352 35 0.016
embryonic organ development GO:0048568 36 0.016
Mouse
embryonic epithelial tube formation GO:0001838 4 0.016
Mouse
regulation of cellular response to stress GO:0080135 244 0.015
regulation of phosphatase activity GO:0010921 81 0.015
response to growth factor GO:0070848 205 0.015
tube closure GO:0060606 3 0.015
Mouse
histone h4 acetylation GO:0043967 47 0.015
developmental growth GO:0048589 48 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
spermatid differentiation GO:0048515 4 0.015
heart morphogenesis GO:0003007 48 0.015
negative regulation of developmental process GO:0051093 247 0.015
epithelial cell development GO:0002064 34 0.015
somitogenesis GO:0001756 2 0.015
spindle assembly GO:0051225 29 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
methylation GO:0032259 106 0.014
multicellular organismal aging GO:0010259 3 0.014
cerebellar cortex development GO:0021695 1 0.014
single organism cellular localization GO:1902580 332 0.014
negative regulation of organelle organization GO:0010639 126 0.014
neural tube closure GO:0001843 3 0.014
Mouse
regulation of chromatin organization GO:1902275 56 0.014
innate immune response GO:0045087 178 0.014
tube morphogenesis GO:0035239 95 0.014
Mouse
muscle structure development GO:0061061 98 0.014
organ morphogenesis GO:0009887 147 0.014
Mouse
regulation of chromosome organization GO:0033044 103 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
sensory perception GO:0007600 103 0.014
positive regulation of organelle organization GO:0010638 195 0.014
histone h3 k27 demethylation GO:0071557 3 0.014
protein localization to nucleus GO:0034504 136 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.013
negative regulation of cell death GO:0060548 345 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.013
protein dealkylation GO:0008214 17 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
positive regulation of cell death GO:0010942 263 0.013
cell fate determination GO:0001709 3 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
regulation of rna splicing GO:0043484 62 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
regulation of protein complex assembly GO:0043254 147 0.013
cell growth GO:0016049 160 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
regionalization GO:0003002 29 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
positive regulation of catabolic process GO:0009896 310 0.013
spindle organization GO:0007051 53 0.013
neuromuscular junction development GO:0007528 3 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
positive regulation of growth GO:0045927 58 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
metencephalon development GO:0022037 2 0.012
embryonic forelimb morphogenesis GO:0035115 4 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
epithelial cell differentiation GO:0030855 141 0.012
negative regulation of phosphatase activity GO:0010923 61 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.012
head development GO:0060322 108 0.012
Mouse
nucleoside monophosphate catabolic process GO:0009125 159 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
blastoderm segmentation GO:0007350 2 0.012
cardiovascular system development GO:0072358 262 0.011
Mouse
negative regulation of proteolysis GO:0045861 132 0.011
pattern specification process GO:0007389 43 0.011
mrna splicing via spliceosome GO:0000398 89 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
nuclear import GO:0051170 106 0.011
jak stat cascade GO:0007259 46 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
myosin filament organization GO:0031033 2 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
regulation of innate immune response GO:0045088 97 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
cerebellum development GO:0021549 2 0.011
small molecule biosynthetic process GO:0044283 157 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
synaptic transmission GO:0007268 61 0.011
rna catabolic process GO:0006401 71 0.011
regulation of mrna processing GO:0050684 48 0.011
respiratory tube development GO:0030323 20 0.011
double strand break repair GO:0006302 101 0.011
regulation of canonical wnt signaling pathway GO:0060828 88 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
sensory organ development GO:0007423 52 0.010
negative regulation of dephosphorylation GO:0035305 63 0.010
sister chromatid segregation GO:0000819 54 0.010
regulation of protein processing GO:0070613 150 0.010
male meiosis GO:0007140 1 0.010
regulation of mitosis GO:0007088 63 0.010
regulation of response to external stimulus GO:0032101 222 0.010
actin filament bundle organization GO:0061572 54 0.010
response to oxygen containing compound GO:1901700 369 0.010
Fly
maintenance of location GO:0051235 112 0.010

SETD2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.028
eye and adnexa disease DOID:1492 150 0.028
nervous system disease DOID:863 431 0.028
eye disease DOID:5614 149 0.028
central nervous system disease DOID:331 186 0.011
neurodegenerative disease DOID:1289 102 0.011