|
|
chromatin modification
|
GO:0016568 |
298 |
0.819
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.784
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.773
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.739
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.701
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.646
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.642
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.629
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.595
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.505
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.502
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.481
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.455
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.449
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.445
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.435
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.435
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.431
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.430
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.407
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.405
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.402
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.397
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.369
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.360
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.349
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.347
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.310
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.305
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.302
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.298
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.290
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.288
|
|
|
|
hepatocyte differentiation
|
GO:0070365 |
1 |
0.286
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.285
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.276
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.265
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.259
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.258
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.257
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.257
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.254
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.242
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.240
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.238
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.232
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.225
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.225
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.223
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.211
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.211
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.210
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.204
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.204
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.202
|
|
|
|
growth
|
GO:0040007 |
202 |
0.198
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.198
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.194
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.191
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.186
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.180
|
|
|
|
positive regulation of transcription during mitosis
|
GO:0045897 |
2 |
0.180
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.177
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.175
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.174
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.171
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.169
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.165
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.162
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.162
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.161
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.159
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.158
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.152
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.152
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.150
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.146
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.146
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.146
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.145
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.143
|
|
|
|
regulation of transcription during mitosis
|
GO:0045896 |
2 |
0.141
|
|
|
|
histone deubiquitination
|
GO:0016578 |
16 |
0.141
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.139
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
3 |
0.136
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.136
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.135
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.132
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.126
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.126
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.125
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.125
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.123
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.123
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.122
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.121
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.118
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.118
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.118
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
0.117
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.116
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.114
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.111
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.111
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.109
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.109
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.107
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.107
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.106
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.105
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.103
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.102
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.100
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.098
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.096
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.095
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.094
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.094
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.093
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.091
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.091
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.091
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.090
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.090
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.090
|
|
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.088
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.088
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.086
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.086
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.086
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.086
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.085
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.085
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.083
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.083
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.083
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.081
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.081
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.081
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.081
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.081
|
Mouse |
|
|
regulation of epithelial cell differentiation involved in kidney development
|
GO:2000696 |
4 |
0.081
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.081
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.080
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.080
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.080
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.079
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.079
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.079
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.079
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.078
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.078
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.078
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.078
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.077
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.076
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.076
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.076
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.076
|
|
|
|
disruption by host of symbiont cells
|
GO:0051852 |
2 |
0.075
|
|
|
|
cellular defense response
|
GO:0006968 |
2 |
0.074
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.074
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.074
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.074
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.074
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.074
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.073
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.073
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.072
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.072
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.071
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.071
|
|
|
|
regulation of double strand break repair via homologous recombination
|
GO:0010569 |
11 |
0.070
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.070
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.070
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.069
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.069
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.069
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.069
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.069
|
|
|
|
cellular response to parathyroid hormone stimulus
|
GO:0071374 |
2 |
0.068
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.068
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.068
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.067
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.067
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.067
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.067
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.066
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.066
|
|
|
|
translation
|
GO:0006412 |
132 |
0.066
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.065
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.065
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.065
|
|
|
|
dna templated transcriptional preinitiation complex assembly
|
GO:0070897 |
5 |
0.064
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.063
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.063
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.062
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.062
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.062
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.062
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.062
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.061
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.060
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.060
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.060
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.060
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.059
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.059
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.058
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.058
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.058
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.058
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.056
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.056
|
|
|
|
leukotriene metabolic process
|
GO:0006691 |
10 |
0.055
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.054
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.054
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.054
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.054
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.053
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.053
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.053
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.053
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.053
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.053
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.052
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.052
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.052
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.051
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.051
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.050
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.050
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.050
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.050
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.050
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.050
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.050
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.049
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.049
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.049
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.049
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.049
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.048
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.048
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.048
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.048
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.048
|
|
|
|
histone h4 k12 acetylation
|
GO:0043983 |
6 |
0.047
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.047
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.047
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.047
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.046
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.046
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.046
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.046
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.046
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.045
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.045
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.045
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.045
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.045
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.045
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.044
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.044
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.044
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.043
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.043
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.043
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.043
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.043
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.043
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.042
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.042
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.042
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.042
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.042
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.041
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.041
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.041
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.041
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.041
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.040
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.040
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.040
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.040
|
|
|
|
regulation of macrophage derived foam cell differentiation
|
GO:0010743 |
14 |
0.040
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.040
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.040
|
Mouse |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.039
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.039
|
|
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
5 |
0.039
|
|
|
|
memory
|
GO:0007613 |
3 |
0.038
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.038
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.038
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.038
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.038
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.038
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.038
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.038
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.038
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.038
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.038
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.037
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.037
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.037
|
|
|
|
regulation of oocyte maturation
|
GO:1900193 |
1 |
0.037
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.037
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.037
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.037
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.037
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.036
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.036
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.036
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.036
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.036
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.036
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.036
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.035
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.035
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.035
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.034
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.034
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.034
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.034
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.034
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.034
|
Mouse |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.034
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.034
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.034
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.034
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.033
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.033
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.033
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.033
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.033
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.033
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.033
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.033
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.033
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.033
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.033
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.033
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.033
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.033
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.033
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.032
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.032
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.032
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.032
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.032
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.031
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
1 |
0.031
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.031
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.031
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.031
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.031
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.031
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.031
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.031
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.030
|
|
|
|
system process
|
GO:0003008 |
349 |
0.030
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.030
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.030
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.030
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.030
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.030
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.030
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.030
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.030
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.029
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.029
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.029
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.029
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.029
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.029
|
|
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.029
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.029
|
|
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.028
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.028
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.028
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.028
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.028
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.028
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.028
|
Mouse |
|
|
eyelid development in camera type eye
|
GO:0061029 |
2 |
0.028
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.028
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.028
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.028
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.027
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.027
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.027
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.027
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.027
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.027
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.027
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.027
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.027
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.027
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.027
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.027
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.027
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.027
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.026
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.026
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.026
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.026
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.026
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.026
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.026
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.026
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.026
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.026
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.026
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.026
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.026
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.026
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.026
|
|
|
|
positive regulation of interleukin 1 production
|
GO:0032732 |
14 |
0.026
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.025
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.025
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.025
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.025
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.025
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.025
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.025
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.025
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.025
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.025
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.025
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.025
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.025
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.025
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.025
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.025
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.024
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.024
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.024
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.024
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.024
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.024
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.024
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.024
|
|
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
35 |
0.024
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.024
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.024
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.024
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
11 |
0.024
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.024
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.024
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.023
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.023
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.023
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.023
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.023
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.023
|
|
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.023
|
Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.023
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
0.023
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.023
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.023
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.023
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.022
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.022
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.022
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.022
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.022
|
|
|
|
foam cell differentiation
|
GO:0090077 |
15 |
0.022
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.022
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.022
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.022
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.022
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.022
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.022
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.022
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.022
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.022
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.022
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.022
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.022
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.022
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.022
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.022
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.021
|
|
