|
|
tie signaling pathway
|
GO:0048014 |
3 |
0.998
|
|
|
|
positive regulation of cytokine secretion involved in immune response
|
GO:0002741 |
2 |
0.916
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.880
|
|
|
|
replacement ossification
|
GO:0036075 |
1 |
0.863
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.806
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.787
|
|
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.771
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.767
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.749
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.749
|
|
|
|
positive regulation of cell junction assembly
|
GO:1901890 |
11 |
0.734
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.718
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.688
|
|
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.672
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.669
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
4 |
0.668
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.655
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.607
|
Human |
|
|
negative regulation of positive chemotaxis
|
GO:0050928 |
1 |
0.602
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.594
|
Human |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.580
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.577
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.572
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.553
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.545
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.541
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.502
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.498
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.498
|
Human |
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.496
|
Human Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.489
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.488
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.488
|
Human Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.487
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.473
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.470
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.469
|
|
|
|
endochondral ossification
|
GO:0001958 |
1 |
0.464
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.457
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.457
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.455
|
|
|
|
positive regulation of adherens junction organization
|
GO:1903393 |
12 |
0.453
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
2 |
0.450
|
|
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
7 |
0.442
|
|
|
|
cytokine secretion involved in immune response
|
GO:0002374 |
7 |
0.435
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.428
|
Human Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.426
|
Human Mouse |
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.425
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.425
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.417
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.417
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.409
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.409
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.406
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.400
|
|
|
|
heparin metabolic process
|
GO:0030202 |
1 |
0.399
|
Human |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.398
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.396
|
Human |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.394
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.385
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.383
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.382
|
Human Mouse |
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.371
|
Human |
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.367
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.365
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.364
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.364
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.362
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.358
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.351
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.350
|
Human Mouse |
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
3 |
0.348
|
Human |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.343
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.342
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.336
|
Human Mouse |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.334
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.333
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.333
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.325
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.320
|
Human |
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.319
|
Human Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.318
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.309
|
Human Mouse |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.306
|
Human |
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.305
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.303
|
Human Mouse |
|
|
skeletal muscle satellite cell proliferation
|
GO:0014841 |
1 |
0.299
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.298
|
Human Mouse |
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.295
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.289
|
Human |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.287
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.284
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.284
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.280
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.276
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.275
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.273
|
Human Mouse |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.271
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.270
|
Human |
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.269
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.264
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.257
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.256
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.250
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.247
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.246
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.246
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.245
|
Human |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.243
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.240
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.239
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.237
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.236
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.235
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.235
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.234
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.234
|
|
|
|
system process
|
GO:0003008 |
349 |
0.231
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.230
|
Human |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.230
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.229
|
Human |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.228
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.222
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.222
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.221
|
Human |
|
|
regulation of nik nf kappab signaling
|
GO:1901222 |
11 |
0.219
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.217
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.216
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.215
|
Human |
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.213
|
Human |
|
|
heart development
|
GO:0007507 |
95 |
0.213
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.206
|
Human Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.205
|
Human |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.204
|
Human |
|
|
protein secretion
|
GO:0009306 |
98 |
0.204
|
Human |
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.204
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.201
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.201
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.199
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.196
|
Human Mouse |
|
|
tissue migration
|
GO:0090130 |
119 |
0.194
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.192
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.191
|
Human |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.187
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.186
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.186
|
Human |
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.186
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.183
|
Human |
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.181
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.179
|
|
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.178
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.175
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.174
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.174
|
Human |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.173
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.171
|
Human Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.170
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.168
|
Human |
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
27 |
0.168
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
0.167
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.167
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.165
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.164
|
Human |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.163
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.160
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.160
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.158
|
|
|
|
complement activation
|
GO:0006956 |
19 |
0.157
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.157
|
Human |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.157
|
Human |
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.156
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.155
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.154
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.154
|
Human |
|
|
response to hormone
|
GO:0009725 |
175 |
0.153
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.151
|
Human |
|
|
blood circulation
|
GO:0008015 |
113 |
0.151
|
Human |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.149
|
Human |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.149
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.147
|
Human |
|
|
angiogenesis involved in wound healing
|
GO:0060055 |
4 |
0.147
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
12 |
0.146
|
|
|
|
regulation of skeletal muscle cell proliferation
|
GO:0014857 |
1 |
0.146
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.146
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.145
|
|
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.144
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.143
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.143
|
Human Mouse |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.142
|
|
|
|
heparin biosynthetic process
|
GO:0030210 |
1 |
0.140
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.138
|
|
|
|
vasculogenesis
|
GO:0001570 |
8 |
0.137
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.137
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.137
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.136
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.135
|
Human |
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.135
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.134
|
Human |
|
|
regulation of establishment or maintenance of cell polarity
|
GO:0032878 |
7 |
0.134
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.133
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.132
|
Human |
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.131
|
Human |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.130
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.129
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.128
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.124
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.123
|
Human |
|
|
peptide secretion
|
GO:0002790 |
51 |
0.123
|
Human |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.121
|
Human Mouse |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.120
|
Human |
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.120
|
Human |
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.120
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.120
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.119
|
Human |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.119
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.117
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.117
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.116
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.116
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.115
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.113
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.113
|
Human |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.112
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.112
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.111
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.109
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.107
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.106
|
Human |
|
|
hemostasis
|
GO:0007599 |
76 |
0.105
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.103
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.103
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.102
|
Human |
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.102
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.102
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.101
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.100
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.099
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.098
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.098
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.097
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.097
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.096
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.096
|
Human |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.096
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.096
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.094
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.093
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.092
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.092
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.092
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.090
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.090
|
Human Mouse |
|
|
regulation of heterotypic cell cell adhesion
|
GO:0034114 |
14 |
0.089
|
Human |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.088
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.088
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.087
|
Human |
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.086
|
Human |
|
|
response to uv
|
GO:0009411 |
73 |
0.085
|
Human |
|
|
response to radiation
|
GO:0009314 |
151 |
0.084
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.083
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.082
|
|
|
|
regulation of satellite cell proliferation
|
GO:0014842 |
1 |
0.081
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.081
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.079
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.078
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.078
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.077
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.077
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.076
|
|
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.076
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.074
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.074
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.073
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.072
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.071
|
|
|
|
protein activation cascade
|
GO:0072376 |
22 |
0.071
|
Human |
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.070
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.070
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.070
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.069
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.069
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.068
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.068
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.067
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.067
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.066
|
|
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
27 |
0.065
|
Human |
|
|
peptide transport
|
GO:0015833 |
74 |
0.065
|
Human |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.064
|
Human |
|
|
vascular wound healing
|
GO:0061042 |
4 |
0.063
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.062
|
Human |
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.062
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.061
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.061
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.061
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.060
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.060
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.059
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.058
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.057
|
|
|
|
aminoglycan biosynthetic process
|
GO:0006023 |
29 |
0.057
|
Human |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.056
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.056
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.056
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.055
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.055
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.055
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.054
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.054
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.054
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.053
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.053
|
Human |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.053
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.052
|
|
|
|
positive regulation of actin cytoskeleton reorganization
|
GO:2000251 |
9 |
0.052
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.051
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.051
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.051
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
15 |
0.050
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.049
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.049
|
|
|
|
regulation of vascular permeability
|
GO:0043114 |
11 |
0.048
|
Human |
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.048
|
Human |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.048
|
Human |
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.048
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.047
|
Human |
|
|
nuclear import
|
GO:0051170 |
106 |
0.046
|
|
|
|
heart trabecula morphogenesis
|
GO:0061384 |
1 |
0.046
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.046
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.045
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.045
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.044
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.044
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.044
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.044
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.044
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.044
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.043
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.043
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.042
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.042
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.042
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.042
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.041
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.041
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.041
|
|
|
|
negative regulation of vascular permeability
|
GO:0043116 |
7 |
0.041
|
Human |
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.040
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.040
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.040
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.039
|
Human |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.039
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.039
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.039
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.039
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.038
|
Human |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.038
|
Human |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.038
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.038
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.038
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.038
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.038
|
|
|
|
positive regulation of heterotypic cell cell adhesion
|
GO:0034116 |
8 |
0.037
|
Human |
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.037
|
Human |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.037
|
Human |
|
|
taxis
|
GO:0042330 |
157 |
0.037
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.037
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.037
|
|
|
|
growth
|
GO:0040007 |
202 |
0.036
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.036
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.036
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.035
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.035
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.035
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.035
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.035
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.035
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.035
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.034
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.034
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.034
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.034
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.033
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.033
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.033
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.033
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.033
|
|
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
13 |
0.033
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.033
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.033
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.033
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.032
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.032
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.032
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.032
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.032
|
Human |
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.032
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.031
|
Human |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.031
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.031
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.031
|
|
|
|
bone morphogenesis
|
GO:0060349 |
10 |
0.031
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.031
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.030
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.030
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.030
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.030
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.029
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.029
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.029
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.029
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.028
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.028
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.028
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.028
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.028
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.028
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.028
|
Human |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.028
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.028
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.028
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.027
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.027
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.027
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.027
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.027
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.027
|
Human Mouse |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.027
|
Human |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.027
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.027
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.026
|
|
|
|
positive regulation of cell cell adhesion
|
GO:0022409 |
22 |
0.026
|
Human |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.026
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.026
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.026
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.026
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.026
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.026
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.025
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.025
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.025
|
|
|
|
regulation of positive chemotaxis
|
GO:0050926 |
14 |
0.025
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.025
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.025
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.025
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.025
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.025
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.025
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.025
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.024
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.024
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.024
|
|
|
|
memory
|
GO:0007613 |
3 |
0.024
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.024
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.024
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.024
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.023
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.023
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.023
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.023
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.023
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.023
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.023
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.023
|
Human |
|
|
oocyte development
|
GO:0048599 |
1 |
0.023
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.023
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.023
|
Human |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.023
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.023
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.023
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.023
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.023
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.022
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.022
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.022
|
Human |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.022
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.022
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.022
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.022
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.022
|
Human |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.022
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.022
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
10 |
0.022
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.022
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.022
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.022
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.022
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.022
|
|
