|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
1.000
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
1.000
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
1.000
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
1.000
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
1.000
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
1.000
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
1.000
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
1.000
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
1.000
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
1.000
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
1.000
|
|
|
|
dna repair
|
GO:0006281 |
198 |
1.000
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
1.000
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
1.000
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
1.000
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
1.000
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
1.000
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
1.000
|
Mouse Fly |
|
|
histone modification
|
GO:0016570 |
251 |
1.000
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
1.000
|
Human Mouse Fly |
|
|
growth
|
GO:0040007 |
202 |
1.000
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
1.000
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
1.000
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
1.000
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
1.000
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
1.000
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
1.000
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
1.000
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
1.000
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
1.000
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
1.000
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
1.000
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
1.000
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
1.000
|
Mouse Fly |
|
|
protein processing
|
GO:0016485 |
226 |
1.000
|
Mouse Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
1.000
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
1.000
|
Worm |
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
1.000
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
1.000
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
1.000
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
1.000
|
Mouse |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
1.000
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
1.000
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
1.000
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
1.000
|
Rat |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
1.000
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
1.000
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
Mouse Rat |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
1.000
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
1.000
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
1.000
|
Worm Fly |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
1.000
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
1.000
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
1.000
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
1.000
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
1.000
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
1.000
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
1.000
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
1.000
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
1.000
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
1.000
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
1.000
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
1.000
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
1.000
|
Mouse |
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
1.000
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
1.000
|
Human Mouse Fly |
|
|
cell division
|
GO:0051301 |
168 |
1.000
|
Zebrafish |
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
1.000
|
Mouse |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
1.000
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
1.000
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
1.000
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
1.000
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
1.000
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
1.000
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
1.000
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
1.000
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
1.000
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
1.000
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
1.000
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
1.000
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
1.000
|
Zebrafish |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
1.000
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.999
|
Fly |
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.999
|
Fly |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.999
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.999
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.999
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.999
|
Human Mouse Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.999
|
Mouse |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.999
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.999
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.999
|
Mouse |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.999
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.999
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.999
|
Rat |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.999
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.999
|
Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.999
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.998
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.998
|
Mouse Fly |
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.998
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.998
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.998
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.998
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.998
|
Mouse Fly |
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.998
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.998
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.998
|
Fly |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.998
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.998
|
Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.998
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.998
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.998
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.998
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.998
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.998
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.998
|
Mouse |
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.997
|
Rat |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.997
|
Mouse |
|
|
oocyte development
|
GO:0048599 |
1 |
0.997
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.997
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.997
|
Mouse |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.997
|
Mouse |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.997
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.997
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.996
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.996
|
Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.995
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.994
|
Zebrafish Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.994
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.994
|
Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.994
|
Fly |
|
|
viral process
|
GO:0016032 |
146 |
0.994
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.994
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.994
|
Fly |
|
|
nuclear division
|
GO:0000280 |
128 |
0.993
|
Worm Fly |
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.993
|
Mouse |
|
|
protein stabilization
|
GO:0050821 |
64 |
0.993
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.993
|
Mouse |
|
|
embryo development
|
GO:0009790 |
123 |
0.993
|
Mouse Worm |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.993
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.992
|
Human Zebrafish Mouse Fly |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.992
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.992
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.992
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.991
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.991
|
Mouse Worm Fly |
|
|
multicellular organism growth
|
GO:0035264 |
8 |
0.991
|
Mouse Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.991
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.991
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.990
|
Fly |
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.990
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.989
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.989
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.988
|
Zebrafish Fly |
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.988
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.988
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.987
|
|
|
|
aging
|
GO:0007568 |
66 |
0.984
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.984
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.984
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.983
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.982
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.982
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.982
|
Zebrafish |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.981
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.981
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.980
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.979
|
Mouse |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.979
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.978
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.978
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.978
|
Fly |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.977
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.977
|
Mouse |
|
|
viral life cycle
|
GO:0019058 |
132 |
0.977
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.976
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.976
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.976
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.975
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.974
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.973
|
Mouse |
|
|
reproductive process
|
GO:0022414 |
106 |
0.972
|
Zebrafish Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.971
|
Mouse Fly |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.969
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.965
|
Mouse Worm |
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.963
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.961
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.961
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.960
|
Zebrafish |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.960
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.959
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.958
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.958
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.954
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.951
|
Zebrafish Fly |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.951
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.951
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.949
|
Fly |
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.949
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.949
|
Mouse Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.948
|
Fly |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.947
|
Zebrafish Mouse |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.946
|
Mouse |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.946
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.945
|
Zebrafish Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.943
|
Fly |
|
|
response to hormone
|
GO:0009725 |
175 |
0.939
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.938
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.937
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.936
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.936
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.936
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.935
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.932
|
Zebrafish Mouse Rat Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.932
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.930
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.930
|
Zebrafish Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.928
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.921
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.920
|
Zebrafish Mouse Rat Fly |
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.919
|
Zebrafish |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.919
|
Rat |
|
|
developmental growth
|
GO:0048589 |
48 |
0.918
|
Human Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.917
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.916
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.916
|
Mouse |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.916
|
Fly |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.915
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.913
|
Fly |
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.910
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.908
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.908
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.906
|
Zebrafish Mouse Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.906
|
Mouse |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.900
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.899
|
Zebrafish Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.899
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.897
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.895
|
Fly |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.894
|
Mouse |
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.893
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.891
|
Zebrafish Mouse |
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.890
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.886
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.885
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.885
|
Mouse Fly |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.879
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.879
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.879
|
Zebrafish |
|
|
response to drug
|
GO:0042493 |
81 |
0.878
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.876
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.871
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.866
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.864
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.863
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.858
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.858
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.857
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.851
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.848
|
Rat |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.846
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.844
|
Mouse |
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.844
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.842
|
Zebrafish |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.839
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.838
|
Human Zebrafish |
|
|
metencephalon development
|
GO:0022037 |
2 |
0.833
|
Mouse |
|
|
eye development
|
GO:0001654 |
42 |
0.832
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.830
|
Fly |
|
|
cell fate specification
|
GO:0001708 |
8 |
0.827
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.826
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.824
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.821
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.820
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.811
|
Zebrafish Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.809
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.806
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.790
|
|
|
|
carbon catabolite activation of transcription from rna polymerase ii promoter
|
GO:0000436 |
3 |
0.786
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.785
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.783
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
31 |
0.780
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.780
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.773
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.772
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.772
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.768
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.767
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.764
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.756
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.756
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.750
|
Zebrafish Mouse |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.749
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.747
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.743
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.730
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.726
|
Rat |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.722
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.721
|
Mouse |
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.719
|
Mouse |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.718
|
Mouse |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.718
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.718
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.717
|
Rat |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.715
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.715
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.714
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.705
|
Mouse Fly |
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.702
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.700
|
Mouse Fly |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.698
|
Mouse |
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.696
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.695
|
Human Zebrafish |
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.694
|
Human |
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.693
|
Zebrafish Mouse |
|
|
response to antibiotic
|
GO:0046677 |
15 |
0.692
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.692
|
Mouse |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.690
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.689
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.680
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.674
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.668
|
Zebrafish Fly |
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
7 |
0.666
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.664
|
Mouse |
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.662
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.656
|
Zebrafish Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.655
|
Rat |
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.653
|
Worm Fly |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.651
|
Mouse |
|
|
meiosis i
|
GO:0007127 |
4 |
0.643
|
Fly |
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.641
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.641
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.634
|
Zebrafish |
|
|
pml body organization
|
GO:0030578 |
2 |
0.631
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.627
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.627
|
Mouse Fly |
|
|
female gonad development
|
GO:0008585 |
10 |
0.626
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.625
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.621
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.620
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.608
|
Mouse Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.599
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.598
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.593
|
Rat |
|
|
autophagy
|
GO:0006914 |
88 |
0.590
|
Mouse Fly |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.587
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.584
|
Fly |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.584
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.581
|
Zebrafish Mouse |
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.581
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.570
|
Zebrafish Mouse |
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.569
|
Zebrafish |
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.566
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.561
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.561
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.559
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.550
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.544
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.543
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.543
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.540
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.539
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
14 |
0.539
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.532
|
Zebrafish Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.530
|
Rat |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.523
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.522
|
Rat |
|
|
sensory organ development
|
GO:0007423 |
52 |
0.520
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.517
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.507
|
Mouse |
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.503
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.501
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.498
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.498
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.497
|
Human |
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.491
|
Rat |
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.485
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.479
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.473
|
Zebrafish Worm Fly |
|
|
gastrulation
|
GO:0007369 |
51 |
0.471
|
Mouse |
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.467
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.467
|
Fly |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.466
|
Mouse Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.457
|
Mouse Worm Fly |
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.453
|
Zebrafish |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.453
|
Fly |
|
|
neuron death
|
GO:0070997 |
65 |
0.450
|
Zebrafish Mouse |
|
|
skin development
|
GO:0043588 |
76 |
0.449
|
Zebrafish |
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.449
|
Human |
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.447
|
Mouse |
|
|
ossification
|
GO:0001503 |
121 |
0.445
|
Human |
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.442
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.440
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.439
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.427
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.426
|
|
|
|
carbon catabolite regulation of transcription from rna polymerase ii promoter
|
GO:0000429 |
3 |
0.420
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.410
|
Mouse |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.406
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.404
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.403
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.401
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.397
|
Mouse |
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.396
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.393
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.392
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.389
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.389
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.383
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.383
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.381
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.374
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
1 |
0.372
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.371
|
Rat |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.371
|
Mouse Fly |
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.364
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.359
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.357
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.356
|
Rat |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.356
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.350
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.350
|
|
|
|
cellular response to alkaloid
|
GO:0071312 |
11 |
0.348
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.345
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.344
|
Fly |
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.342
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.340
|
Zebrafish Fly |
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.338
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.337
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.336
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.335
|
Mouse |
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.333
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.332
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.332
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.330
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.329
|
Fly |
|
|
regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043516 |
20 |
0.317
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.315
|
Mouse |
|
|
histone h4 k5 acetylation
|
GO:0043981 |
15 |
0.307
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.303
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.301
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.299
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.295
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.294
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.294
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.291
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
29 |
0.288
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.287
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.286
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.285
|
Fly |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.281
|
Zebrafish Fly |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.279
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.273
|
Fly |
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.272
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.272
|
|
|
|
positive regulation of gluconeogenesis
|
GO:0045722 |
1 |
0.268
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.265
|
|
|
|
chromatin mediated maintenance of transcription
|
GO:0048096 |
2 |
0.265
|
|
|
|
cellular response to drug
|
GO:0035690 |
27 |
0.264
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.264
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.262
|
Zebrafish |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.262
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
8 |
0.255
|
Worm Fly |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.254
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.250
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.244
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.243
|
Mouse Fly |
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.238
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.238
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.236
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.236
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.234
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.233
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.233
|
Mouse |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.232
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.228
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.224
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.221
|
Mouse |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.216
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.214
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.210
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.210
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.208
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.208
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.208
|
Fly |
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.206
|
Mouse |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.205
|
Fly |
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.205
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.203
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.199
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.197
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.197
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.197
|
|
