Homo sapiens

6 known processes

HARS

histidyl-tRNA synthetase

(Aliases: FLJ20491,HRS)

HARS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ncrna metabolic process GO:0034660 108 0.289
Yeast
post embryonic development GO:0009791 2 0.270
Worm
protein localization to organelle GO:0033365 280 0.117
system process GO:0003008 349 0.115
oogenesis GO:0048477 2 0.113
regulation of nucleoside metabolic process GO:0009118 209 0.100
purine nucleoside triphosphate catabolic process GO:0009146 392 0.095
positive regulation of gtpase activity GO:0043547 166 0.092
cell development GO:0048468 328 0.082
Worm
vesicle mediated transport GO:0016192 371 0.081
Worm
single organism cellular localization GO:1902580 332 0.076
purine nucleotide catabolic process GO:0006195 405 0.073
intracellular protein transport GO:0006886 270 0.072
female gamete generation GO:0007292 2 0.069
purine nucleoside catabolic process GO:0006152 398 0.069
oocyte differentiation GO:0009994 2 0.066
endocytosis GO:0006897 159 0.066
Worm
cellular protein complex assembly GO:0043623 188 0.063
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.063
purine ribonucleoside catabolic process GO:0046130 398 0.062
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.059
ribonucleoside catabolic process GO:0042454 406 0.058
regulation of purine nucleotide metabolic process GO:1900542 264 0.057
positive regulation of nucleotide metabolic process GO:0045981 230 0.057
purine ribonucleotide catabolic process GO:0009154 404 0.056
posttranscriptional regulation of gene expression GO:0010608 213 0.054
establishment of protein localization to organelle GO:0072594 172 0.053
ribosome biogenesis GO:0042254 48 0.052
multicellular organismal aging GO:0010259 3 0.051
positive regulation of nucleotide catabolic process GO:0030813 185 0.049
positive regulation of gtp catabolic process GO:0033126 166 0.049
translation GO:0006412 132 0.047
Yeast
reproductive process GO:0022414 106 0.046
Worm
single organism reproductive process GO:0044702 98 0.046
Worm
glycosyl compound catabolic process GO:1901658 413 0.045
nucleotide catabolic process GO:0009166 408 0.045
regulation of gtp catabolic process GO:0033124 180 0.045
cellular amino acid metabolic process GO:0006520 116 0.044
Yeast
oocyte development GO:0048599 1 0.044
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.043
organophosphate catabolic process GO:0046434 430 0.042
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.042
ncrna processing GO:0034470 83 0.042
mitotic cell cycle GO:0000278 326 0.041
purine ribonucleoside metabolic process GO:0046128 437 0.041
ribonucleoprotein complex biogenesis GO:0022613 116 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.040
photoreceptor cell differentiation GO:0046530 2 0.040
chromatin organization GO:0006325 351 0.040
nucleoside triphosphate catabolic process GO:0009143 394 0.040
positive regulation of hydrolase activity GO:0051345 331 0.039
cytoplasmic transport GO:0016482 379 0.038
actin filament based process GO:0030029 224 0.038
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
organelle fission GO:0048285 149 0.036
secretion by cell GO:0032940 226 0.035
nucleoside catabolic process GO:0009164 408 0.035
regulation of cell differentiation GO:0045595 393 0.035
gtp metabolic process GO:0046039 239 0.035
regulation of nucleotide catabolic process GO:0030811 205 0.035
guanosine containing compound catabolic process GO:1901069 239 0.035
positive regulation of nucleoside metabolic process GO:0045979 186 0.034
cellular amine metabolic process GO:0044106 41 0.034
regulation of gtpase activity GO:0043087 180 0.033
neurological system process GO:0050877 163 0.033
rrna metabolic process GO:0016072 40 0.033
nucleus localization GO:0051647 1 0.032
gtp catabolic process GO:0006184 237 0.032
ribonucleoside triphosphate catabolic process GO:0009203 391 0.032
rna processing GO:0006396 255 0.031
regulation of purine nucleotide catabolic process GO:0033121 205 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
protein import GO:0017038 130 0.030
biological adhesion GO:0022610 331 0.029
reproductive system development GO:0061458 56 0.029
amine metabolic process GO:0009308 44 0.029
defense response GO:0006952 315 0.029
positive regulation of developmental process GO:0051094 314 0.029
Worm
single organism membrane organization GO:0044802 268 0.029
chromosome segregation GO:0007059 114 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
cardiovascular system development GO:0072358 262 0.028
ribonucleoprotein complex subunit organization GO:0071826 81 0.028
response to biotic stimulus GO:0009607 276 0.028
microtubule based process GO:0007017 210 0.028
ribonucleotide catabolic process GO:0009261 405 0.028
nucleoside triphosphate metabolic process GO:0009141 422 0.028
developmental programmed cell death GO:0010623 3 0.027
lipid metabolic process GO:0006629 381 0.027
carbohydrate derivative biosynthetic process GO:1901137 207 0.027
establishment of nucleus localization GO:0040023 1 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
rna interference GO:0016246 4 0.026
developmental process involved in reproduction GO:0003006 66 0.026
Worm
purine containing compound catabolic process GO:0072523 411 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.025
oligodendrocyte development GO:0014003 6 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
positive regulation of catabolic process GO:0009896 310 0.024
organelle assembly GO:0070925 176 0.024
memory GO:0007613 3 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
circulatory system development GO:0072359 262 0.023
regulation of chromosome organization GO:0033044 103 0.023
sex differentiation GO:0007548 45 0.022
regulation of cellular component movement GO:0051270 334 0.022
behavior GO:0007610 112 0.022
purine nucleoside monophosphate metabolic process GO:0009126 186 0.022
reproductive structure development GO:0048608 55 0.022
protein catabolic process GO:0030163 325 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.021
cell adhesion GO:0007155 325 0.021
protein acylation GO:0043543 138 0.021
rna splicing GO:0008380 131 0.021
mitotic cell cycle process GO:1903047 286 0.021
anatomical structure formation involved in morphogenesis GO:0048646 284 0.020
cell cell signaling GO:0007267 155 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
neurogenesis GO:0022008 169 0.020
nuclear division GO:0000280 128 0.019
stem cell differentiation GO:0048863 93 0.019
reproduction GO:0000003 63 0.019
Worm
dephosphorylation GO:0016311 209 0.019
protein targeting GO:0006605 187 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
cellular component morphogenesis GO:0032989 314 0.019
mitotic nuclear division GO:0007067 119 0.019
spermatid development GO:0007286 4 0.019
regulation of cell migration GO:0030334 289 0.019
cellular protein catabolic process GO:0044257 261 0.018
growth GO:0040007 202 0.018
Worm
guanosine containing compound metabolic process GO:1901068 244 0.018
toxin transport GO:1901998 4 0.018
positive regulation of transport GO:0051050 336 0.018
trna metabolic process GO:0006399 35 0.018
Yeast
regulation of transferase activity GO:0051338 355 0.018
regulation of locomotion GO:0040012 329 0.018
response to external biotic stimulus GO:0043207 261 0.018
rna splicing via transesterification reactions GO:0000375 90 0.018
purine nucleoside monophosphate catabolic process GO:0009128 158 0.018
atp catabolic process GO:0006200 157 0.017
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.017
spermatid differentiation GO:0048515 4 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
regulation of response to external stimulus GO:0032101 222 0.017
chromatin modification GO:0016568 298 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
translational initiation GO:0006413 48 0.017
oxidation reduction process GO:0055114 396 0.017
maintenance of location GO:0051235 112 0.017
cell projection organization GO:0030030 252 0.016
regulation of membrane potential GO:0042391 95 0.016
neuron differentiation GO:0030182 138 0.016
nuclear migration GO:0007097 1 0.016
regulation of meiosis GO:0040020 3 0.016
inclusion body assembly GO:0070841 17 0.016
protein polymerization GO:0051258 71 0.016
locomotory behavior GO:0007626 1 0.016
response to other organism GO:0051707 261 0.016
sister chromatid segregation GO:0000819 54 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
lipid biosynthetic process GO:0008610 177 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
cell division GO:0051301 168 0.015
small molecule biosynthetic process GO:0044283 157 0.015
gonad development GO:0008406 34 0.015
cellular response to lipid GO:0071396 127 0.015
protein dephosphorylation GO:0006470 81 0.015
response to virus GO:0009615 126 0.015
regulation of kinase activity GO:0043549 314 0.015
regulation of translation GO:0006417 89 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
trachea development GO:0060438 1 0.015
immune system development GO:0002520 195 0.014
embryonic eye morphogenesis GO:0048048 2 0.014
regulation of cell cycle process GO:0010564 266 0.014
histone modification GO:0016570 251 0.014
regulation of dna metabolic process GO:0051052 153 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
peripheral nervous system development GO:0007422 2 0.014
adult locomotory behavior GO:0008344 1 0.014
negative regulation of developmental process GO:0051093 247 0.014
protein targeting to nucleus GO:0044744 104 0.014
protein localization to membrane GO:0072657 160 0.014
actin cytoskeleton organization GO:0030036 207 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
tissue morphogenesis GO:0048729 96 0.014
embryonic morphogenesis GO:0048598 85 0.014
nervous system development GO:0007399 293 0.014
regulation of ion transport GO:0043269 189 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
protein dna complex subunit organization GO:0071824 80 0.013
regulation of cell motility GO:2000145 299 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
organelle localization GO:0051640 84 0.013
single organismal cell cell adhesion GO:0016337 148 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
ameboidal type cell migration GO:0001667 135 0.013
neuronal action potential GO:0019228 9 0.013
microtubule polymerization GO:0046785 18 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
neuron development GO:0048666 113 0.013
response to lipid GO:0033993 206 0.013
regulation of cell cycle GO:0051726 393 0.013
vasculature development GO:0001944 181 0.013
establishment of protein localization to mitochondrion GO:0072655 22 0.013
cellular response to external stimulus GO:0071496 111 0.013
positive regulation of protein complex assembly GO:0031334 86 0.013
single organism cell adhesion GO:0098602 179 0.013
cellular lipid metabolic process GO:0044255 303 0.013
associative learning GO:0008306 1 0.013
cell morphogenesis GO:0000902 296 0.013
rna modification GO:0009451 27 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
negative regulation of protein modification process GO:0031400 200 0.013
regulation of meiotic cell cycle GO:0051445 4 0.012
rna catabolic process GO:0006401 71 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
covalent chromatin modification GO:0016569 254 0.012
multi organism cellular process GO:0044764 156 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
cell part morphogenesis GO:0032990 137 0.012
defense response to other organism GO:0098542 129 0.012
embryo development GO:0009790 123 0.012
Worm
anterior posterior axis specification embryo GO:0008595 2 0.012
coenzyme metabolic process GO:0006732 65 0.012
action potential GO:0001508 34 0.012
metal ion transport GO:0030001 272 0.012
positive regulation of cytokine production GO:0001819 167 0.012
regulation of protein localization GO:0032880 296 0.012
response to growth factor GO:0070848 205 0.012
sexual reproduction GO:0019953 37 0.012
Worm
organophosphate biosynthetic process GO:0090407 163 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
alcohol metabolic process GO:0006066 114 0.011
negative regulation of cell death GO:0060548 345 0.011
regulation of binding GO:0051098 111 0.011
cellular response to nutrient levels GO:0031669 69 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
regulation of protein complex assembly GO:0043254 147 0.011
ras protein signal transduction GO:0007265 73 0.011
generation of neurons GO:0048699 152 0.011
response to hormone GO:0009725 175 0.011
regulation of cell division GO:0051302 116 0.011
determination of adult lifespan GO:0008340 2 0.011
regulation of protein transport GO:0051223 213 0.011
atp metabolic process GO:0046034 176 0.011
regulation of growth GO:0040008 165 0.011
Worm
positive regulation of organelle organization GO:0010638 195 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
blastoderm segmentation GO:0007350 2 0.011
blastocyst development GO:0001824 3 0.011
eye photoreceptor cell differentiation GO:0001754 2 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
apoptotic signaling pathway GO:0097190 268 0.011
establishment or maintenance of cell polarity GO:0007163 31 0.011
response to nutrient levels GO:0031667 81 0.011
negative regulation of immune system process GO:0002683 136 0.011
single organism nuclear import GO:1902593 104 0.011
modification dependent protein catabolic process GO:0019941 209 0.010
sperm egg recognition GO:0035036 3 0.010
multicellular organismal reproductive process GO:0048609 40 0.010
Worm
positive regulation of cell death GO:0010942 263 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
response to wounding GO:0009611 168 0.010
maintenance of protein location in cell GO:0032507 56 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
anterior posterior axis specification GO:0009948 2 0.010
protein import into nucleus GO:0006606 104 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
alcohol biosynthetic process GO:0046165 52 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
rrna processing GO:0006364 35 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.010
response to abiotic stimulus GO:0009628 336 0.010
regulation of cell development GO:0060284 161 0.010
mrna splicing via spliceosome GO:0000398 89 0.010
secretion GO:0046903 254 0.010

HARS disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.016
nervous system disease DOID:863 431 0.016
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.011
retinal disease DOID:5679 118 0.010
retinal degeneration DOID:8466 89 0.010
usher syndrome DOID:0050439 12 0.001