Homo sapiens

55 known processes

DGCR8

DiGeorge syndrome critical region gene 8

(Aliases: C22orf12,pasha,DGCRK6,Gy1)

DGCR8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.755
gene silencing by mirna GO:0035195 23 0.620
primary mirna processing GO:0031053 3 0.535
dsrna fragmentation GO:0031050 13 0.437
response to dsrna GO:0043331 25 0.283
rna processing GO:0006396 255 0.244
cellular response to dsrna GO:0071359 19 0.225
ncrna metabolic process GO:0034660 108 0.214
posttranscriptional gene silencing by rna GO:0035194 25 0.205
defense response to bacterium GO:0042742 63 0.183
response to other organism GO:0051707 261 0.155
cellular response to organic cyclic compound GO:0071407 127 0.151
response to biotic stimulus GO:0009607 276 0.148
defense response to gram positive bacterium GO:0050830 29 0.140
posttranscriptional regulation of gene expression GO:0010608 213 0.137
production of small rna involved in gene silencing by rna GO:0070918 13 0.109
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.105
mitotic cell cycle GO:0000278 326 0.102
lipid metabolic process GO:0006629 381 0.098
defense response to gram negative bacterium GO:0050829 14 0.097
female gamete generation GO:0007292 2 0.092
Fly
defense response GO:0006952 315 0.090
ncrna processing GO:0034470 83 0.089
mitotic cell cycle process GO:1903047 286 0.088
response to external biotic stimulus GO:0043207 261 0.086
post embryonic development GO:0009791 2 0.081
regulation of mirna metabolic process GO:2000628 5 0.074
regulation of gene expression epigenetic GO:0040029 73 0.071
cell division GO:0051301 168 0.070
rna phosphodiester bond hydrolysis GO:0090501 35 0.070
microtubule based process GO:0007017 210 0.067
posttranscriptional gene silencing GO:0016441 25 0.066
blastoderm segmentation GO:0007350 2 0.062
response to organic cyclic compound GO:0014070 204 0.058
gene silencing GO:0016458 49 0.055
oocyte differentiation GO:0009994 2 0.054
Fly
multicellular organismal aging GO:0010259 3 0.054
determination of adult lifespan GO:0008340 2 0.049
anterior posterior axis specification embryo GO:0008595 2 0.043
regulation of cell cycle GO:0051726 393 0.043
response to nitrogen compound GO:1901698 184 0.042
microtubule cytoskeleton organization GO:0000226 176 0.042
mrna metabolic process GO:0016071 175 0.041
segmentation GO:0035282 4 0.041
mirna metabolic process GO:0010586 10 0.040
regeneration GO:0031099 4 0.040
cellular amino acid metabolic process GO:0006520 116 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.036
oocyte development GO:0048599 1 0.036
cell development GO:0048468 328 0.036
Fly
amine metabolic process GO:0009308 44 0.035
cellular amine metabolic process GO:0044106 41 0.035
anterior posterior axis specification GO:0009948 2 0.035
oogenesis GO:0048477 2 0.035
Fly
head development GO:0060322 108 0.033
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
single organism cellular localization GO:1902580 332 0.033
pre mirna processing GO:0031054 8 0.033
cytokinesis GO:0000910 96 0.032
actin filament based process GO:0030029 224 0.030
immune response GO:0006955 307 0.030
regulation of establishment of protein localization GO:0070201 242 0.030
embryo development GO:0009790 123 0.030
negative regulation of cell cycle GO:0045786 193 0.030
tripartite regional subdivision GO:0007351 2 0.029
regulation of cell cycle process GO:0010564 266 0.029
regulation of multi organism process GO:0043900 157 0.028
regulation of oocyte development GO:0060281 1 0.028
chemical homeostasis GO:0048878 306 0.028
regulation of cellular ketone metabolic process GO:0010565 50 0.027
nervous system development GO:0007399 293 0.027
Fly
neuromuscular junction development GO:0007528 3 0.026
regulation of cell maturation GO:1903429 3 0.026
mitochondrion organization GO:0007005 156 0.026
single organism membrane organization GO:0044802 268 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
positive regulation of organelle organization GO:0010638 195 0.024
brain development GO:0007420 97 0.024
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
intracellular protein transport GO:0006886 270 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
regulation of protein transport GO:0051223 213 0.022
positive regulation of cell death GO:0010942 263 0.022
ras protein signal transduction GO:0007265 73 0.022
apoptotic signaling pathway GO:0097190 268 0.021
cytoplasmic transport GO:0016482 379 0.021
spindle organization GO:0007051 53 0.021
rna splicing via transesterification reactions GO:0000375 90 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
regulation of immune response GO:0050776 201 0.020
regulation of cellular response to stress GO:0080135 244 0.020
chromosome segregation GO:0007059 114 0.020
positive regulation of protein transport GO:0051222 135 0.020
regulation of meiotic cell cycle GO:0051445 4 0.020
multi organism cellular process GO:0044764 156 0.020
neurogenesis GO:0022008 169 0.019
membrane organization GO:0061024 292 0.019
organophosphate catabolic process GO:0046434 430 0.019
chromatin organization GO:0006325 351 0.019
regulation of cell differentiation GO:0045595 393 0.019
regulation of cell cycle phase transition GO:1901987 126 0.019
cellular ketone metabolic process GO:0042180 80 0.019
small gtpase mediated signal transduction GO:0007264 78 0.019
reproductive process GO:0022414 106 0.019
Fly
rna catabolic process GO:0006401 71 0.019
purine nucleoside catabolic process GO:0006152 398 0.019
neurotransmitter secretion GO:0007269 4 0.019
protein localization to organelle GO:0033365 280 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
morphogenesis of embryonic epithelium GO:0016331 4 0.019
response to fungus GO:0009620 4 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.018
protein targeting GO:0006605 187 0.018
regulation of intracellular transport GO:0032386 195 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
mrna processing GO:0006397 133 0.018
rna splicing GO:0008380 131 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
Fly
negative regulation of cell cycle process GO:0010948 121 0.018
rho protein signal transduction GO:0007266 26 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
endocytosis GO:0006897 159 0.018
glycosyl compound catabolic process GO:1901658 413 0.017
negative regulation of cell death GO:0060548 345 0.017
regulation of rna splicing GO:0043484 62 0.017
dephosphorylation GO:0016311 209 0.017
mitotic nuclear division GO:0007067 119 0.017
locomotory behavior GO:0007626 1 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
somitogenesis GO:0001756 2 0.017
organelle assembly GO:0070925 176 0.017
chromatin modification GO:0016568 298 0.017
organelle fission GO:0048285 149 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
regulation of viral process GO:0050792 103 0.016
primary neural tube formation GO:0014020 3 0.016
purine containing compound catabolic process GO:0072523 411 0.016
histone modification GO:0016570 251 0.016
cellular protein complex assembly GO:0043623 188 0.016
cell cycle phase transition GO:0044770 173 0.016
rna interference GO:0016246 4 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
secretion by cell GO:0032940 226 0.015
meiotic chromosome segregation GO:0045132 4 0.015
peptidyl lysine modification GO:0018205 144 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
compound eye development GO:0048749 1 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.014
nucleoside catabolic process GO:0009164 408 0.014
actin cytoskeleton organization GO:0030036 207 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
viral life cycle GO:0019058 132 0.014
regulation of transferase activity GO:0051338 355 0.014
establishment of tissue polarity GO:0007164 3 0.014
mrna splicing via spliceosome GO:0000398 89 0.014
nitrogen compound transport GO:0071705 191 0.014
cellular homeostasis GO:0019725 196 0.014
protein localization to nucleus GO:0034504 136 0.014
dna replication GO:0006260 116 0.014
vesicle mediated transport GO:0016192 371 0.014
hindbrain development GO:0030902 3 0.014
establishment of protein localization to organelle GO:0072594 172 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
regulation of secretion by cell GO:1903530 177 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
positive regulation of transport GO:0051050 336 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
sperm egg recognition GO:0035036 3 0.013
protein acetylation GO:0006473 116 0.013
inner ear morphogenesis GO:0042472 4 0.013
cellular component morphogenesis GO:0032989 314 0.013
metencephalon development GO:0022037 2 0.013
protein autophosphorylation GO:0046777 123 0.013
tissue regeneration GO:0042246 3 0.013
regulation of protein localization GO:0032880 296 0.013
intracellular receptor signaling pathway GO:0030522 104 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
neural tube closure GO:0001843 3 0.013
mitotic sister chromatid segregation GO:0000070 53 0.013
regulation of secretion GO:0051046 194 0.013
neuron differentiation GO:0030182 138 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
neuron projection regeneration GO:0031102 1 0.013
cation homeostasis GO:0055080 189 0.013
mapk cascade GO:0000165 288 0.013
spermatid development GO:0007286 4 0.012
ion homeostasis GO:0050801 230 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
myosin filament assembly GO:0031034 2 0.012
interspecies interaction between organisms GO:0044419 156 0.012
memory GO:0007613 3 0.012
protein import GO:0017038 130 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
response to oxygen containing compound GO:1901700 369 0.012
cardiovascular system development GO:0072358 262 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
defense response to fungus GO:0050832 4 0.012
positive regulation of immune system process GO:0002684 283 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
adult locomotory behavior GO:0008344 1 0.012
spermatid differentiation GO:0048515 4 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
cell morphogenesis GO:0000902 296 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.012
viral process GO:0016032 146 0.011
g1 s transition of mitotic cell cycle GO:0000082 78 0.011
regulation of protein targeting GO:1903533 91 0.011
neural tube formation GO:0001841 3 0.011
negative regulation of viral process GO:0048525 66 0.011
cellular chemical homeostasis GO:0055082 180 0.011
organ morphogenesis GO:0009887 147 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
nuclear transport GO:0051169 179 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
regulation of cell motility GO:2000145 299 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
intracellular mrna localization GO:0008298 1 0.011
regulation of protein kinase activity GO:0045859 289 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
sister chromatid segregation GO:0000819 54 0.011
protein oligomerization GO:0051259 173 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
cell projection morphogenesis GO:0048858 129 0.011
gtp metabolic process GO:0046039 239 0.011
sexual reproduction GO:0019953 37 0.011
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
protein localization to membrane GO:0072657 160 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
reproduction GO:0000003 63 0.010
Fly
cellular cation homeostasis GO:0030003 163 0.010
mrna catabolic process GO:0006402 56 0.010
myosin filament organization GO:0031033 2 0.010
endomembrane system organization GO:0010256 196 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
autophagy GO:0006914 88 0.010
methylation dependent chromatin silencing GO:0006346 3 0.010
regulation of neurotransmitter secretion GO:0046928 3 0.010
regulation of kinase activity GO:0043549 314 0.010
secretion GO:0046903 254 0.010
mitochondrial membrane organization GO:0007006 40 0.010
endochondral bone morphogenesis GO:0060350 3 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
meiosis i GO:0007127 4 0.010
multi organism reproductive process GO:0044703 54 0.010
Fly

DGCR8 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.040
cancer DOID:162 167 0.027
disease of cellular proliferation DOID:14566 174 0.027
organ system cancer DOID:0050686 164 0.027
muscular disease DOID:0080000 114 0.021
gastrointestinal system cancer DOID:3119 52 0.021
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
muscle tissue disease DOID:66 113 0.017
myopathy DOID:423 104 0.015
muscular dystrophy DOID:9884 51 0.015
central nervous system disease DOID:331 186 0.014
eye and adnexa disease DOID:1492 150 0.010