Homo sapiens

55 known processes

GOT2

glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)

(Aliases: KATIV,mitAAT,KAT4,FLJ40994)

GOT2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.626
aspartate metabolic process GO:0006531 4 0.544
glycerol metabolic process GO:0006071 4 0.538
alditol metabolic process GO:0019400 5 0.414
citrate metabolic process GO:0006101 2 0.387
generation of precursor metabolites and energy GO:0006091 68 0.306
dicarboxylic acid biosynthetic process GO:0043650 4 0.293
Fly
carbohydrate metabolic process GO:0005975 207 0.291
glutamate metabolic process GO:0006536 10 0.274
Fly
purine nucleoside monophosphate metabolic process GO:0009126 186 0.221
aspartate family amino acid catabolic process GO:0009068 5 0.211
cofactor metabolic process GO:0051186 87 0.189
cellular respiration GO:0045333 21 0.188
protein processing GO:0016485 226 0.188
cofactor biosynthetic process GO:0051188 31 0.176
tricarboxylic acid cycle GO:0006099 4 0.167
regulation of proteolysis GO:0030162 293 0.166
post embryonic development GO:0009791 2 0.148
single organism carbohydrate metabolic process GO:0044723 193 0.133
regulation of peptidase activity GO:0052547 180 0.132
polyol metabolic process GO:0019751 32 0.124
ribonucleoside monophosphate catabolic process GO:0009158 158 0.124
vesicle mediated transport GO:0016192 371 0.109
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.100
alcohol metabolic process GO:0006066 114 0.100
coenzyme metabolic process GO:0006732 65 0.098
nucleotide biosynthetic process GO:0009165 109 0.090
cellular carbohydrate metabolic process GO:0044262 84 0.085
purine ribonucleotide biosynthetic process GO:0009152 79 0.081
determination of adult lifespan GO:0008340 2 0.080
nucleocytoplasmic transport GO:0006913 176 0.077
endocytosis GO:0006897 159 0.075
cation transport GO:0006812 331 0.074
cytoplasmic transport GO:0016482 379 0.067
organic hydroxy compound metabolic process GO:1901615 147 0.067
regulation of endopeptidase activity GO:0052548 170 0.065
cation transmembrane transport GO:0098655 238 0.065
inorganic ion transmembrane transport GO:0098660 231 0.064
cell cell signaling GO:0007267 155 0.064
Fly
cellular amino acid metabolic process GO:0006520 116 0.064
dicarboxylic acid metabolic process GO:0043648 29 0.063
anatomical structure formation involved in morphogenesis GO:0048646 284 0.063
tricarboxylic acid metabolic process GO:0072350 4 0.059
protein maturation GO:0051604 233 0.059
inorganic cation transmembrane transport GO:0098662 194 0.059
embryo development GO:0009790 123 0.058
alpha amino acid metabolic process GO:1901605 72 0.057
ribose phosphate biosynthetic process GO:0046390 82 0.055
epithelium development GO:0060429 227 0.055
carboxylic acid catabolic process GO:0046395 71 0.055
purine ribonucleoside metabolic process GO:0046128 437 0.055
fatty acid metabolic process GO:0006631 115 0.054
dicarboxylic acid catabolic process GO:0043649 9 0.054
positive regulation of peptidase activity GO:0010952 88 0.053
nucleoside triphosphate metabolic process GO:0009141 422 0.051
monocarboxylic acid metabolic process GO:0032787 185 0.050
response to abiotic stimulus GO:0009628 336 0.050
cellular amino acid biosynthetic process GO:0008652 30 0.050
Fly
activation of cysteine type endopeptidase activity GO:0097202 57 0.049
protein localization to organelle GO:0033365 280 0.049
carbohydrate derivative biosynthetic process GO:1901137 207 0.048
multicellular organismal aging GO:0010259 3 0.047
ribonucleoside triphosphate metabolic process GO:0009199 412 0.047
glycosyl compound biosynthetic process GO:1901659 27 0.046
regulation of feeding behavior GO:0060259 3 0.045
energy derivation by oxidation of organic compounds GO:0015980 43 0.044
atp metabolic process GO:0046034 176 0.043
growth GO:0040007 202 0.043
ion transmembrane transport GO:0034220 338 0.043
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.043
protein targeting GO:0006605 187 0.042
spermatid development GO:0007286 4 0.041
positive regulation of developmental process GO:0051094 314 0.041
positive regulation of proteolysis GO:0045862 142 0.041
ribonucleotide biosynthetic process GO:0009260 81 0.040
zymogen activation GO:0031638 70 0.040
positive regulation of hydrolase activity GO:0051345 331 0.040
single organism cellular localization GO:1902580 332 0.039
coenzyme biosynthetic process GO:0009108 24 0.039
actin filament based process GO:0030029 224 0.039
dna catabolic process GO:0006308 49 0.039
cellular protein complex assembly GO:0043623 188 0.038
purine nucleoside triphosphate metabolic process GO:0009144 412 0.038
system process GO:0003008 349 0.038
spermatid differentiation GO:0048515 4 0.037
intracellular protein transport GO:0006886 270 0.036
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
cellular component morphogenesis GO:0032989 314 0.032
translation GO:0006412 132 0.032
maintenance of location GO:0051235 112 0.031
neurological system process GO:0050877 163 0.031
cell development GO:0048468 328 0.031
actin cytoskeleton organization GO:0030036 207 0.031
ribonucleoside monophosphate metabolic process GO:0009161 187 0.030
small molecule catabolic process GO:0044282 92 0.030
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.029
ion homeostasis GO:0050801 230 0.029
establishment of protein localization to organelle GO:0072594 172 0.029
carboxylic acid biosynthetic process GO:0046394 97 0.028
Fly
oogenesis GO:0048477 2 0.028
monovalent inorganic cation transport GO:0015672 128 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.027
organic acid biosynthetic process GO:0016053 97 0.027
Fly
biological adhesion GO:0022610 331 0.027
receptor mediated endocytosis GO:0006898 84 0.027
regulation of cellular amine metabolic process GO:0033238 11 0.027
secretion by cell GO:0032940 226 0.027
organonitrogen compound biosynthetic process GO:1901566 200 0.026
Fly
adult locomotory behavior GO:0008344 1 0.025
regulation of generation of precursor metabolites and energy GO:0043467 27 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
endoplasmic reticulum unfolded protein response GO:0030968 16 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
locomotory behavior GO:0007626 1 0.025
nucleoside monophosphate catabolic process GO:0009125 159 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
myosin filament assembly GO:0031034 2 0.023
female gamete generation GO:0007292 2 0.023
cellular ion homeostasis GO:0006873 168 0.023
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
oxidoreduction coenzyme metabolic process GO:0006733 19 0.022
glutamine family amino acid metabolic process GO:0009064 17 0.021
Fly
sulfur compound metabolic process GO:0006790 101 0.021
regulation of transferase activity GO:0051338 355 0.021
organic hydroxy compound biosynthetic process GO:1901617 71 0.021
small molecule biosynthetic process GO:0044283 157 0.021
Fly
epithelial cell differentiation GO:0030855 141 0.020
response to hormone GO:0009725 175 0.020
regulation of ion transport GO:0043269 189 0.020
intracellular receptor signaling pathway GO:0030522 104 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
striated muscle myosin thick filament assembly GO:0071688 2 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
chemical homeostasis GO:0048878 306 0.020
organelle assembly GO:0070925 176 0.019
positive regulation of organelle organization GO:0010638 195 0.019
tissue homeostasis GO:0001894 63 0.019
behavior GO:0007610 112 0.019
response to peptide GO:1901652 65 0.019
mitochondrial membrane organization GO:0007006 40 0.018
lipid homeostasis GO:0055088 39 0.018
nuclear transport GO:0051169 179 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
cell adhesion GO:0007155 325 0.018
protein tetramerization GO:0051262 47 0.018
neuron differentiation GO:0030182 138 0.018
negative regulation of proteolysis GO:0045861 132 0.018
myosin filament organization GO:0031033 2 0.017
nucleoside triphosphate biosynthetic process GO:0009142 20 0.017
protein autoprocessing GO:0016540 4 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
regulation of developmental growth GO:0048638 30 0.017
detection of stimulus GO:0051606 85 0.017
positive regulation of cell death GO:0010942 263 0.017
microtubule based process GO:0007017 210 0.017
phototransduction GO:0007602 3 0.017
muscle cell differentiation GO:0042692 63 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
cell projection organization GO:0030030 252 0.017
2 oxoglutarate metabolic process GO:0006103 4 0.016
cellular ketone metabolic process GO:0042180 80 0.016
dephosphorylation GO:0016311 209 0.016
amino acid activation GO:0043038 12 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
cellular component disassembly GO:0022411 92 0.016
protein homooligomerization GO:0051260 100 0.016
regulation of behavior GO:0050795 82 0.016
alcohol biosynthetic process GO:0046165 52 0.016
hydrogen transport GO:0006818 23 0.016
single organism membrane organization GO:0044802 268 0.016
ventral spinal cord development GO:0021517 1 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
negative regulation of protein modification process GO:0031400 200 0.015
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.015
reproductive structure development GO:0048608 55 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
regulation of membrane potential GO:0042391 95 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
ribonucleoside biosynthetic process GO:0042455 25 0.015
generation of neurons GO:0048699 152 0.015
secretion GO:0046903 254 0.015
metal ion transport GO:0030001 272 0.015
cellular amine metabolic process GO:0044106 41 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
nadh metabolic process GO:0006734 1 0.015
transmembrane transport GO:0055085 399 0.015
neuromuscular junction development GO:0007528 3 0.015
reproduction GO:0000003 63 0.015
Worm
cellular component assembly involved in morphogenesis GO:0010927 73 0.015
embryo development ending in birth or egg hatching GO:0009792 34 0.015
anion transport GO:0006820 161 0.015
positive regulation of growth GO:0045927 58 0.015
microtubule cytoskeleton organization GO:0000226 176 0.014
protein homotetramerization GO:0051289 28 0.014
cellular cation homeostasis GO:0030003 163 0.014
response to nitrogen compound GO:1901698 184 0.014
regulation of growth GO:0040008 165 0.014
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.014
response to other organism GO:0051707 261 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
positive regulation of endopeptidase activity GO:0010950 84 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
multi organism cellular process GO:0044764 156 0.013
sodium ion transmembrane transport GO:0035725 59 0.013
nucleoside biosynthetic process GO:0009163 26 0.013
cellular lipid metabolic process GO:0044255 303 0.013
cellular chemical homeostasis GO:0055082 180 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
amine metabolic process GO:0009308 44 0.013
nucleotide catabolic process GO:0009166 408 0.013
regulation of kinase activity GO:0043549 314 0.013
single organism nuclear import GO:1902593 104 0.013
purine ribonucleoside biosynthetic process GO:0046129 23 0.013
apoptotic nuclear changes GO:0030262 13 0.013
coenzyme a metabolic process GO:0015936 6 0.012
muscle structure development GO:0061061 98 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
spinal cord development GO:0021510 4 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
mitochondrion organization GO:0007005 156 0.012
immune response GO:0006955 307 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
regulation of oxidative phosphorylation GO:0002082 3 0.012
defense response GO:0006952 315 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
nucleoside catabolic process GO:0009164 408 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.012
organophosphate catabolic process GO:0046434 430 0.012
response to oxidative stress GO:0006979 121 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
negative regulation of transferase activity GO:0051348 124 0.012
negative regulation of catalytic activity GO:0043086 335 0.011
single organism reproductive process GO:0044702 98 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.011
reproductive process GO:0022414 106 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
ribonucleoside bisphosphate metabolic process GO:0033875 7 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
muscle cell development GO:0055001 29 0.011
response to oxygen containing compound GO:1901700 369 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
response to hypoxia GO:0001666 96 0.011
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
cilium morphogenesis GO:0060271 75 0.010
response to peptide hormone GO:0043434 61 0.010
purine containing compound catabolic process GO:0072523 411 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
regulation of hormone levels GO:0010817 125 0.010
actomyosin structure organization GO:0031032 59 0.010
neuroblast proliferation GO:0007405 4 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010
nucleobase containing compound transport GO:0015931 51 0.010
nervous system development GO:0007399 293 0.010
Fly
reproductive system development GO:0061458 56 0.010
protein acylation GO:0043543 138 0.010
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.010

GOT2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.787
inherited metabolic disorder DOID:655 242 0.787
carbohydrate metabolic disorder DOID:2978 55 0.257
amino acid metabolic disorder DOID:9252 50 0.074
sensory system disease DOID:0050155 203 0.069
eye and adnexa disease DOID:1492 150 0.069
nervous system disease DOID:863 431 0.069
central nervous system disease DOID:331 186 0.056
neurodegenerative disease DOID:1289 102 0.053
immune system disease DOID:2914 155 0.052
hematopoietic system disease DOID:74 100 0.019
neuromuscular disease DOID:440 38 0.017
neuropathy DOID:870 52 0.017
retinal disease DOID:5679 118 0.016
retinal degeneration DOID:8466 89 0.016
eye disease DOID:5614 149 0.016
retinitis pigmentosa DOID:10584 51 0.015
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
organ system cancer DOID:0050686 164 0.015