Homo sapiens

40 known processes

FBXL5

F-box and leucine-rich repeat protein 5

(Aliases: FBL4,FBL5,FLR1)

FBXL5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.252
cellular protein catabolic process GO:0044257 261 0.227
cellular macromolecule catabolic process GO:0044265 380 0.182
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 15 0.179
modification dependent macromolecule catabolic process GO:0043632 212 0.154
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.128
determination of adult lifespan GO:0008340 2 0.082
post embryonic development GO:0009791 2 0.077
protein catabolic process GO:0030163 325 0.071
apoptotic signaling pathway GO:0097190 268 0.070
positive regulation of catabolic process GO:0009896 310 0.070
Mouse
modification dependent protein catabolic process GO:0019941 209 0.068
microtubule based process GO:0007017 210 0.067
dna replication GO:0006260 116 0.066
ubiquitin dependent protein catabolic process GO:0006511 206 0.063
metal ion transport GO:0030001 272 0.063
cytoplasmic transport GO:0016482 379 0.063
vesicle mediated transport GO:0016192 371 0.060
small gtpase mediated signal transduction GO:0007264 78 0.060
microtubule cytoskeleton organization GO:0000226 176 0.057
protein ubiquitination GO:0016567 314 0.055
regulation of protein stability GO:0031647 87 0.049
peptide transport GO:0015833 74 0.048
female gamete generation GO:0007292 2 0.046
multicellular organismal aging GO:0010259 3 0.045
locomotory behavior GO:0007626 1 0.040
single organism cellular localization GO:1902580 332 0.039
proteasomal protein catabolic process GO:0010498 176 0.038
regulation of cellular component biogenesis GO:0044087 281 0.036
segmentation GO:0035282 4 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
vesicle organization GO:0016050 62 0.033
protein localization to organelle GO:0033365 280 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.032
negative regulation of cell death GO:0060548 345 0.032
immune response GO:0006955 307 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.030
lipid localization GO:0010876 106 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
cellular macromolecular complex assembly GO:0034622 324 0.028
regulation of cell cycle process GO:0010564 266 0.028
regulation of cellular response to stress GO:0080135 244 0.028
maintenance of location GO:0051235 112 0.027
oogenesis GO:0048477 2 0.027
positive regulation of nucleotide metabolic process GO:0045981 230 0.026
membrane organization GO:0061024 292 0.026
posttranscriptional regulation of gene expression GO:0010608 213 0.026
regulation of cell cycle GO:0051726 393 0.026
single organism membrane organization GO:0044802 268 0.026
golgi vesicle transport GO:0048193 80 0.026
intracellular protein transport GO:0006886 270 0.025
cellular amino acid metabolic process GO:0006520 116 0.025
regulation of microtubule based process GO:0032886 74 0.025
regulation of protein localization GO:0032880 296 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
nervous system development GO:0007399 293 0.024
negative regulation of cellular component organization GO:0051129 235 0.024
cation transport GO:0006812 331 0.024
regulation of cytoskeleton organization GO:0051493 177 0.024
cellular lipid metabolic process GO:0044255 303 0.024
compound eye development GO:0048749 1 0.024
wnt signaling pathway GO:0016055 156 0.024
ras protein signal transduction GO:0007265 73 0.023
adult locomotory behavior GO:0008344 1 0.023
cellular homeostasis GO:0019725 196 0.023
nitrogen compound transport GO:0071705 191 0.023
positive regulation of cell cycle GO:0045787 140 0.023
organelle assembly GO:0070925 176 0.023
positive regulation of transport GO:0051050 336 0.023
system process GO:0003008 349 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
hindbrain development GO:0030902 3 0.022
regulation of gtpase activity GO:0043087 180 0.022
enzyme linked receptor protein signaling pathway GO:0007167 303 0.021
chromosome segregation GO:0007059 114 0.021
lipid metabolic process GO:0006629 381 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
circadian behavior GO:0048512 2 0.021
cellular amine metabolic process GO:0044106 41 0.021
cell cell signaling GO:0007267 155 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
Mouse
neuromuscular junction development GO:0007528 3 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
negative regulation of transport GO:0051051 176 0.020
regulation of protein catabolic process GO:0042176 155 0.019
Mouse
lipid biosynthetic process GO:0008610 177 0.019
post golgi vesicle mediated transport GO:0006892 36 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
protein stabilization GO:0050821 64 0.019
regulation of secretion GO:0051046 194 0.019
cell projection organization GO:0030030 252 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.018
response to nitrogen compound GO:1901698 184 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
organelle localization GO:0051640 84 0.018
negative regulation of protein modification process GO:0031400 200 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
regulation of centrosome cycle GO:0046605 15 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
mitotic cell cycle GO:0000278 326 0.018
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
cell development GO:0048468 328 0.017
response to oxygen containing compound GO:1901700 369 0.017
vacuole organization GO:0007033 44 0.017
organelle fission GO:0048285 149 0.017
amine metabolic process GO:0009308 44 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
reproductive process GO:0022414 106 0.017
regulation of protein ubiquitination GO:0031396 95 0.017
negative regulation of gliogenesis GO:0014014 3 0.017
regulation of cytoplasmic transport GO:1903649 149 0.016
negative regulation of cell cycle GO:0045786 193 0.016
organ formation GO:0048645 3 0.016
secretion GO:0046903 254 0.016
response to abiotic stimulus GO:0009628 336 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.016
regulation of organelle assembly GO:1902115 40 0.016
organophosphate catabolic process GO:0046434 430 0.016
sterol transport GO:0015918 39 0.016
regulation of kinase activity GO:0043549 314 0.016
stress activated protein kinase signaling cascade GO:0031098 94 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
regulation of transferase activity GO:0051338 355 0.016
oocyte development GO:0048599 1 0.016
neuron remodeling GO:0016322 2 0.016
cell part morphogenesis GO:0032990 137 0.016
small molecule biosynthetic process GO:0044283 157 0.016
immune effector process GO:0002252 159 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
memory GO:0007613 3 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
regulation of mapk cascade GO:0043408 262 0.015
dephosphorylation GO:0016311 209 0.015
epidermis morphogenesis GO:0048730 3 0.015
mitotic cell cycle process GO:1903047 286 0.015
oocyte differentiation GO:0009994 2 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.015
positive regulation of cell death GO:0010942 263 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
regulation of intracellular transport GO:0032386 195 0.015
regulation of microtubule cytoskeleton organization GO:0070507 61 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
actin filament based process GO:0030029 224 0.015
mapk cascade GO:0000165 288 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
developmental programmed cell death GO:0010623 3 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
glycerolipid metabolic process GO:0046486 107 0.014
neurogenesis GO:0022008 169 0.014
response to metal ion GO:0010038 84 0.014
protein dna complex assembly GO:0065004 64 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
mitochondrion organization GO:0007005 156 0.014
regulation of ion transmembrane transport GO:0034765 132 0.014
chemical homeostasis GO:0048878 306 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
establishment of organelle localization GO:0051656 59 0.014
chromatin modification GO:0016568 298 0.014
lipid transport GO:0006869 90 0.014
steroid metabolic process GO:0008202 94 0.014
long term memory GO:0007616 2 0.013
rho protein signal transduction GO:0007266 26 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
neural tube closure GO:0001843 3 0.013
regulation of protein kinase activity GO:0045859 289 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
mitotic nuclear division GO:0007067 119 0.013
defense response GO:0006952 315 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
innate immune response GO:0045087 178 0.013
organic hydroxy compound transport GO:0015850 63 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
response to radiation GO:0009314 151 0.013
cellular component disassembly GO:0022411 92 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
protein dephosphorylation GO:0006470 81 0.013
morphogenesis of a polarized epithelium GO:0001738 3 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
regulation of secretion by cell GO:1903530 177 0.012
vacuolar transport GO:0007034 34 0.012
cellular cation homeostasis GO:0030003 163 0.012
cell morphogenesis GO:0000902 296 0.012
viral life cycle GO:0019058 132 0.012
anion transport GO:0006820 161 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
prostate gland development GO:0030850 3 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
cellular ion homeostasis GO:0006873 168 0.012
response to organonitrogen compound GO:0010243 156 0.012
cellular protein complex assembly GO:0043623 188 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
mammary gland morphogenesis GO:0060443 2 0.012
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
cytoskeleton dependent intracellular transport GO:0030705 21 0.012
response to biotic stimulus GO:0009607 276 0.012
cation transmembrane transport GO:0098655 238 0.012
neuron development GO:0048666 113 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of protein targeting GO:1903533 91 0.012
cerebral cortex radially oriented cell migration GO:0021799 1 0.012
regulation of proteolysis GO:0030162 293 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
nuclear transport GO:0051169 179 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
microtubule based transport GO:0010970 21 0.011
blastoderm segmentation GO:0007350 2 0.011
protein polyubiquitination GO:0000209 110 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
regulation of growth rate GO:0040009 1 0.011
glycoprotein metabolic process GO:0009100 110 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
regulation of autophagy GO:0010506 52 0.011
meiosis i GO:0007127 4 0.011
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.011
early endosome to golgi transport GO:0034498 3 0.011
gtp metabolic process GO:0046039 239 0.011
regulation of multi organism process GO:0043900 157 0.011
inner ear morphogenesis GO:0042472 4 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
signal transduction by p53 class mediator GO:0072331 72 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
protein localization to synapse GO:0035418 2 0.011
lysosomal transport GO:0007041 33 0.011
organic anion transport GO:0015711 103 0.011
endocytosis GO:0006897 159 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
microtubule organizing center organization GO:0031023 62 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
response to inorganic substance GO:0010035 127 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of glycoprotein metabolic process GO:1903018 19 0.011
positive regulation of protein transport GO:0051222 135 0.011
regulation of mitosis GO:0007088 63 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
negative regulation of multi organism process GO:0043901 92 0.010
ion homeostasis GO:0050801 230 0.010
cation homeostasis GO:0055080 189 0.010
divalent inorganic cation transport GO:0072511 158 0.010
primary neural tube formation GO:0014020 3 0.010
nucleoside triphosphate catabolic process GO:0009143 394 0.010
vasculature development GO:0001944 181 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
regulation of cell division GO:0051302 116 0.010
positive regulation of protein ubiquitination GO:0031398 53 0.010
negative regulation of meiotic cell cycle GO:0051447 2 0.010
cellular response to external stimulus GO:0071496 111 0.010

FBXL5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.111
musculoskeletal system disease DOID:17 223 0.047
inherited metabolic disorder DOID:655 242 0.035
muscular disease DOID:0080000 114 0.029
muscle tissue disease DOID:66 113 0.026
myopathy DOID:423 104 0.015
muscular dystrophy DOID:9884 51 0.015