Homo sapiens

111 known processes

ARFGAP1

ADP-ribosylation factor GTPase activating protein 1

(Aliases: HRIHFB2281,ARF1GAP,MGC39924)

ARFGAP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribonucleoside triphosphate metabolic process GO:0009199 412 0.195
glycosyl compound catabolic process GO:1901658 413 0.190
post embryonic development GO:0009791 2 0.189
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.179
gtp catabolic process GO:0006184 237 0.176
purine ribonucleotide catabolic process GO:0009154 404 0.155
purine nucleoside triphosphate catabolic process GO:0009146 392 0.153
organophosphate catabolic process GO:0046434 430 0.152
regulation of gtp catabolic process GO:0033124 180 0.145
mrna metabolic process GO:0016071 175 0.142
regulation of nucleotide catabolic process GO:0030811 205 0.136
cellular macromolecule catabolic process GO:0044265 380 0.136
membrane organization GO:0061024 292 0.121
Yeast
cell projection organization GO:0030030 252 0.121
positive regulation of gtp catabolic process GO:0033126 166 0.115
purine ribonucleoside metabolic process GO:0046128 437 0.114
nucleotide catabolic process GO:0009166 408 0.113
rho protein signal transduction GO:0007266 26 0.111
nucleoside phosphate catabolic process GO:1901292 412 0.108
nucleoside triphosphate catabolic process GO:0009143 394 0.104
positive regulation of catabolic process GO:0009896 310 0.096
purine containing compound catabolic process GO:0072523 411 0.095
protein ubiquitination GO:0016567 314 0.094
purine nucleoside catabolic process GO:0006152 398 0.093
single organism membrane organization GO:0044802 268 0.092
Yeast
rna processing GO:0006396 255 0.090
gtp metabolic process GO:0046039 239 0.090
positive regulation of nucleotide metabolic process GO:0045981 230 0.087
regulation of mapk cascade GO:0043408 262 0.087
endomembrane system organization GO:0010256 196 0.085
Yeast
postsynaptic membrane organization GO:0001941 2 0.079
purine nucleoside triphosphate metabolic process GO:0009144 412 0.075
regulation of gtpase activity GO:0043087 180 0.075
locomotory behavior GO:0007626 1 0.075
nervous system development GO:0007399 293 0.075
guanosine containing compound metabolic process GO:1901068 244 0.072
ribonucleoside triphosphate catabolic process GO:0009203 391 0.068
multicellular organismal aging GO:0010259 3 0.067
nucleoside catabolic process GO:0009164 408 0.067
positive regulation of gtpase activity GO:0043547 166 0.065
determination of adult lifespan GO:0008340 2 0.063
positive regulation of cellular catabolic process GO:0031331 284 0.063
guanosine containing compound catabolic process GO:1901069 239 0.062
negative regulation of phosphate metabolic process GO:0045936 267 0.061
protein localization to membrane GO:0072657 160 0.061
Yeast
regulation of cell cycle GO:0051726 393 0.059
regulation of cellular amino acid metabolic process GO:0006521 6 0.059
g protein coupled receptor signaling pathway GO:0007186 207 0.058
cell morphogenesis GO:0000902 296 0.057
neuromuscular junction development GO:0007528 3 0.057
regulation of map kinase activity GO:0043405 108 0.057
purine ribonucleoside catabolic process GO:0046130 398 0.056
regulation of transferase activity GO:0051338 355 0.055
secretion GO:0046903 254 0.054
cytoplasmic transport GO:0016482 379 0.053
Yeast
regulation of nucleoside metabolic process GO:0009118 209 0.051
mitotic cell cycle process GO:1903047 286 0.050
cellular component morphogenesis GO:0032989 314 0.050
cellular amino acid metabolic process GO:0006520 116 0.049
regulation of neural precursor cell proliferation GO:2000177 4 0.048
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.048
cell development GO:0048468 328 0.048
negative regulation of catalytic activity GO:0043086 335 0.047
regulation of nucleotide metabolic process GO:0006140 269 0.046
brain development GO:0007420 97 0.044
taxis GO:0042330 157 0.044
amine metabolic process GO:0009308 44 0.044
organonitrogen compound biosynthetic process GO:1901566 200 0.042
negative regulation of protein metabolic process GO:0051248 391 0.040
secretion by cell GO:0032940 226 0.040
nucleoside triphosphate metabolic process GO:0009141 422 0.040
cell adhesion GO:0007155 325 0.037
signal transduction by phosphorylation GO:0023014 297 0.037
cellular response to ammonium ion GO:0071242 4 0.037
ribonucleoside catabolic process GO:0042454 406 0.037
regulation of secretion GO:0051046 194 0.036
mitotic nuclear division GO:0007067 119 0.036
central nervous system development GO:0007417 123 0.035
positive regulation of apoptotic process GO:0043065 246 0.035
protein catabolic process GO:0030163 325 0.034
regulation of nervous system development GO:0051960 88 0.034
cell projection morphogenesis GO:0048858 129 0.034
positive regulation of nucleoside metabolic process GO:0045979 186 0.034
cellular ketone metabolic process GO:0042180 80 0.034
cellular macromolecular complex assembly GO:0034622 324 0.034
positive regulation of hydrolase activity GO:0051345 331 0.034
oogenesis GO:0048477 2 0.033
establishment of protein localization to membrane GO:0090150 121 0.033
Yeast
regulation of response to external stimulus GO:0032101 222 0.033
synaptic transmission GO:0007268 61 0.033
mitotic cell cycle GO:0000278 326 0.032
female gamete generation GO:0007292 2 0.032
chemotaxis GO:0006935 157 0.032
positive regulation of proteolysis GO:0045862 142 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
regulation of secretion by cell GO:1903530 177 0.031
regulation of axon guidance GO:1902667 3 0.030
rna splicing GO:0008380 131 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
modification dependent protein catabolic process GO:0019941 209 0.029
mapk cascade GO:0000165 288 0.029
spermatid development GO:0007286 4 0.029
regulation of protein serine threonine kinase activity GO:0071900 179 0.029
positive regulation of cell death GO:0010942 263 0.028
negative regulation of phosphorylation GO:0042326 174 0.028
cellular amine metabolic process GO:0044106 41 0.028
organophosphate biosynthetic process GO:0090407 163 0.028
neuron death GO:0070997 65 0.028
vesicle mediated transport GO:0016192 371 0.028
Yeast
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
Fly
negative regulation of protein phosphorylation GO:0001933 140 0.028
negative regulation of protein modification process GO:0031400 200 0.027
chemical homeostasis GO:0048878 306 0.027
positive regulation of transferase activity GO:0051347 227 0.027
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
neuron projection development GO:0031175 106 0.026
neurogenesis GO:0022008 169 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
cell cell signaling GO:0007267 155 0.026
protein modification by small protein conjugation GO:0032446 342 0.025
single organism cellular localization GO:1902580 332 0.025
Yeast
nerve development GO:0021675 4 0.025
glycerolipid metabolic process GO:0046486 107 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
mitochondrion transport along microtubule GO:0047497 3 0.025
spermatid differentiation GO:0048515 4 0.025
regulation of establishment of protein localization GO:0070201 242 0.024
regulation of synaptic vesicle endocytosis GO:1900242 1 0.024
biological adhesion GO:0022610 331 0.024
regulation of protein transport GO:0051223 213 0.024
segmentation GO:0035282 4 0.023
regulation of neuron death GO:1901214 56 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.023
cellular protein catabolic process GO:0044257 261 0.023
small gtpase mediated signal transduction GO:0007264 78 0.023
Fly
purine nucleotide catabolic process GO:0006195 405 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.022
regulation of kinase activity GO:0043549 314 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
dermatan sulfate proteoglycan biosynthetic process GO:0050651 4 0.022
regulation of protein kinase activity GO:0045859 289 0.022
regulation of rho protein signal transduction GO:0035023 79 0.022
peptidyl lysine acetylation GO:0018394 101 0.022
positive regulation of kinase activity GO:0033674 204 0.022
intracellular protein transport GO:0006886 270 0.022
Yeast
brain morphogenesis GO:0048854 1 0.022
endothelial cell proliferation GO:0001935 65 0.021
negative regulation of protein kinase activity GO:0006469 98 0.021
organelle fission GO:0048285 149 0.021
regulation of protein catabolic process GO:0042176 155 0.021
dendritic spine morphogenesis GO:0060997 3 0.020
regulation of ras gtpase activity GO:0032318 128 0.020
cell part morphogenesis GO:0032990 137 0.020
apoptotic signaling pathway GO:0097190 268 0.020
microtubule based process GO:0007017 210 0.020
cranial nerve development GO:0021545 4 0.020
regulation of synaptic vesicle recycling GO:1903421 1 0.020
neuron differentiation GO:0030182 138 0.020
negative regulation of cellular component organization GO:0051129 235 0.019
regulation of rab gtpase activity GO:0032313 39 0.019
regulation of cellular response to growth factor stimulus GO:0090287 76 0.019
regulation of proteolysis GO:0030162 293 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
cell morphogenesis involved in differentiation GO:0000904 144 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
positive regulation of rab gtpase activity GO:0032851 39 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
positive regulation of rho protein signal transduction GO:0035025 4 0.019
neurotransmitter secretion GO:0007269 4 0.019
negative regulation of catabolic process GO:0009895 104 0.019
regulation of protein localization GO:0032880 296 0.019
generation of neurons GO:0048699 152 0.019
protein processing GO:0016485 226 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
rna splicing via transesterification reactions GO:0000375 90 0.019
histone modification GO:0016570 251 0.018
protein maturation GO:0051604 233 0.018
negative regulation of cell death GO:0060548 345 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
receptor mediated endocytosis GO:0006898 84 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
cellular response to oxidative stress GO:0034599 85 0.018
protein localization to organelle GO:0033365 280 0.017
negative regulation of cellular catabolic process GO:0031330 83 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
response to abiotic stimulus GO:0009628 336 0.017
regulation of neuron projection development GO:0010975 57 0.017
head development GO:0060322 108 0.017
behavior GO:0007610 112 0.017
purine nucleotide biosynthetic process GO:0006164 84 0.017
rna catabolic process GO:0006401 71 0.017
forebrain neuron differentiation GO:0021879 3 0.016
regulation of protein ubiquitination GO:0031396 95 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
neuron development GO:0048666 113 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.016
negative regulation of protein transport GO:0051224 75 0.016
neuron projection morphogenesis GO:0048812 50 0.016
positive regulation of transport GO:0051050 336 0.016
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.016
anion transport GO:0006820 161 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
regulation of cell differentiation GO:0045595 393 0.015
maintenance of location GO:0051235 112 0.015
regulation of cell projection organization GO:0031344 107 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.015
mrna catabolic process GO:0006402 56 0.015
oocyte development GO:0048599 1 0.015
mrna splicing via spliceosome GO:0000398 89 0.015
histone acetylation GO:0016573 93 0.015
cell growth GO:0016049 160 0.015
cell projection assembly GO:0030031 126 0.015
metencephalon development GO:0022037 2 0.015
response to reactive oxygen species GO:0000302 61 0.015
cellular response to dna damage stimulus GO:0006974 379 0.014
cellular homeostasis GO:0019725 196 0.014
vasodilation GO:0042311 4 0.014
protein acetylation GO:0006473 116 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
mrna processing GO:0006397 133 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.013
dna repair GO:0006281 198 0.013
regulation of dna metabolic process GO:0051052 153 0.013
nitrogen compound transport GO:0071705 191 0.013
rab protein signal transduction GO:0032482 4 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
endosomal transport GO:0016197 129 0.013
golgi vesicle transport GO:0048193 80 0.013
Yeast
exocytosis GO:0006887 71 0.013
cdc42 protein signal transduction GO:0032488 4 0.013
cell division GO:0051301 168 0.013
cell type specific apoptotic process GO:0097285 125 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
negative regulation of developmental process GO:0051093 247 0.013
forebrain generation of neurons GO:0021872 3 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
regulation of intracellular transport GO:0032386 195 0.013
hindbrain development GO:0030902 3 0.013
positive regulation of organelle organization GO:0010638 195 0.013
system process GO:0003008 349 0.012
negative regulation of transport GO:0051051 176 0.012
epithelium development GO:0060429 227 0.012
ras protein signal transduction GO:0007265 73 0.012
Fly
regulation of cellular component movement GO:0051270 334 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
hemopoiesis GO:0030097 180 0.012
chromatin modification GO:0016568 298 0.012
covalent chromatin modification GO:0016569 254 0.012
regulation of cellular response to stress GO:0080135 244 0.012
single organism reproductive process GO:0044702 98 0.012
meiosis i GO:0007127 4 0.012
anatomical structure homeostasis GO:0060249 100 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
negative regulation of nucleotide metabolic process GO:0045980 29 0.012
mitochondrion organization GO:0007005 156 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
regulation of chromosome organization GO:0033044 103 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
protein targeting GO:0006605 187 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
cellular cation homeostasis GO:0030003 163 0.012
actin cytoskeleton organization GO:0030036 207 0.012
Yeast
regulation of dephosphorylation GO:0035303 96 0.012
innate immune response GO:0045087 178 0.012
regulation of body fluid levels GO:0050878 99 0.012
mitochondrion localization GO:0051646 10 0.012
negative regulation of kinase activity GO:0033673 106 0.011
detection of mechanical stimulus GO:0050982 4 0.011
neuroblast proliferation GO:0007405 4 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
positive regulation of g protein coupled receptor protein signaling pathway GO:0045745 9 0.011
vesicle organization GO:0016050 62 0.011
internal peptidyl lysine acetylation GO:0018393 97 0.011
response to oxygen containing compound GO:1901700 369 0.011
activation of cysteine type endopeptidase activity GO:0097202 57 0.011
regulation of neurogenesis GO:0050767 82 0.011
organelle assembly GO:0070925 176 0.011
cardiovascular system development GO:0072358 262 0.011
mitochondrion distribution GO:0048311 3 0.011
oxidation reduction process GO:0055114 396 0.011
cellular ion homeostasis GO:0006873 168 0.011
ribonucleoprotein complex biogenesis GO:0022613 116 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
regulation of kidney size GO:0035564 2 0.011
oocyte differentiation GO:0009994 2 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
dendritic spine organization GO:0097061 4 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
circulatory system development GO:0072359 262 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
regulation of endopeptidase activity GO:0052548 170 0.010
response to oxidative stress GO:0006979 121 0.010
sulfur compound metabolic process GO:0006790 101 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
regulation of ion transport GO:0043269 189 0.010
regulation of mitotic cell cycle phase transition GO:1901990 118 0.010
cation homeostasis GO:0055080 189 0.010
internal protein amino acid acetylation GO:0006475 101 0.010
endocytosis GO:0006897 159 0.010
neurological system process GO:0050877 163 0.010
establishment of organelle localization GO:0051656 59 0.010
negative regulation of organelle organization GO:0010639 126 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.010
regulation of proteasomal protein catabolic process GO:0061136 87 0.010
regulation of peroxidase activity GO:2000468 2 0.010
dephosphorylation GO:0016311 209 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
protein targeting to membrane GO:0006612 42 0.010
glycosaminoglycan biosynthetic process GO:0006024 27 0.010
cell chemotaxis GO:0060326 112 0.010
regulation of peptidase activity GO:0052547 180 0.010
positive regulation of protein ubiquitination GO:0031398 53 0.010
actin filament based process GO:0030029 224 0.010
Yeast
proteoglycan metabolic process GO:0006029 29 0.010

ARFGAP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.190
nervous system disease DOID:863 431 0.190
immune system disease DOID:2914 155 0.033
musculoskeletal system disease DOID:17 223 0.028
connective tissue disease DOID:65 109 0.021
disease of metabolism DOID:0014667 295 0.019
carbohydrate metabolic disorder DOID:2978 55 0.019
inherited metabolic disorder DOID:655 242 0.019
neurodegenerative disease DOID:1289 102 0.017
bone disease DOID:0080001 88 0.012
disease of mental health DOID:150 70 0.011