|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.299
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.285
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.206
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.191
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.180
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.171
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.150
|
Human Yeast Worm |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.148
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.146
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.140
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.139
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.138
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.138
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.133
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.131
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.131
|
Human Yeast Worm |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.127
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.127
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.122
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.120
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.119
|
Human Yeast Worm |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.117
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.117
|
Human Yeast Worm |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.115
|
Human Yeast Worm |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.114
|
Human Yeast Worm |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.113
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.112
|
Human Yeast Worm |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.108
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.107
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.105
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.105
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.104
|
Human Yeast Worm |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.102
|
Worm |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.101
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.098
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.094
|
Human Yeast Worm |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.094
|
Human Yeast |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.093
|
Yeast |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.093
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.092
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.091
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.090
|
Human Yeast Worm |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.088
|
Human Yeast Worm |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.088
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.088
|
Human Yeast Worm |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.085
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.084
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.083
|
Human Yeast Worm |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.082
|
Worm |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.081
|
Yeast |
|
|
immune system development
|
GO:0002520 |
195 |
0.080
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.080
|
Human Yeast Worm |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.080
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.080
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.077
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.077
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.077
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.075
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.074
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.074
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.073
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.072
|
Human Yeast Worm |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.072
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.070
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.069
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.067
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.067
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.066
|
Human Yeast Worm |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.065
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.065
|
Yeast |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.065
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.065
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.064
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.062
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.062
|
Human Yeast Worm |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.062
|
Human Yeast Worm |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.061
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.061
|
Yeast |
|
|
defense response
|
GO:0006952 |
315 |
0.061
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.060
|
Human Yeast Worm |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.060
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.059
|
Human Yeast Worm |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.059
|
Human Yeast Worm |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.059
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.058
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.058
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.058
|
Human Yeast Worm |
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.057
|
Human Yeast Worm |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.057
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.057
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.057
|
Yeast |
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.056
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.056
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.055
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.054
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.054
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.054
|
Yeast |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.054
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.053
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.052
|
Human Yeast Worm |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.052
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.051
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.051
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.050
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.050
|
Worm |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.050
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.050
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.050
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.049
|
Fly |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.049
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.049
|
Yeast |
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.048
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.048
|
Yeast |
|
|
innate immune response
|
GO:0045087 |
178 |
0.048
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.048
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.047
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.046
|
Human |
|
|
protein deacylation
|
GO:0035601 |
39 |
0.046
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.045
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.045
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.045
|
Yeast |
|
|
cytokine production
|
GO:0001816 |
247 |
0.045
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.044
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.044
|
Human Yeast Worm |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.044
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.044
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.044
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.044
|
Yeast |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.044
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.044
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.044
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.044
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.044
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.044
|
Worm |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.043
|
Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.043
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.043
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.042
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.042
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.042
|
Yeast |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.042
|
Worm |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.042
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.041
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.041
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.040
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.040
|
Worm |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.040
|
Human Yeast Worm |
|
|
membrane organization
|
GO:0061024 |
292 |
0.040
|
Yeast |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.040
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.039
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.039
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.038
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.038
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.038
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.037
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.037
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.037
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.036
|
Human Yeast Worm |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.036
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.036
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.036
|
Human |
|
|
taxis
|
GO:0042330 |
157 |
0.035
|
Fly |
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.035
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.035
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.034
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.034
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.034
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.034
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.034
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.034
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.034
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.034
|
Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.034
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.034
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.034
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.033
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.033
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.033
|
Yeast |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.033
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.033
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.032
|
Human Yeast Worm |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.032
|
Human Yeast Worm |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.032
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.031
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.031
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.031
|
Fly |
|
|
cell development
|
GO:0048468 |
328 |
0.031
|
Fly |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.031
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.030
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.030
|
Yeast |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.030
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.030
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.030
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.030
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.030
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.029
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.029
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.029
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.029
|
Fly |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.029
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.029
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.029
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.029
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.029
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.029
|
Yeast |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.029
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.029
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.028
|
Human Yeast Worm |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.028
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.028
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.028
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.028
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.028
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.027
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.027
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.027
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.027
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.027
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.027
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.027
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.027
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.026
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.026
|
Yeast |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.026
|
Human Yeast Worm |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.026
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.026
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.026
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.026
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.026
|
|
|
|
system process
|
GO:0003008 |
349 |
0.026
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.026
|
Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.025
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.025
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.025
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.025
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.025
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.025
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.025
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.024
|
Human Yeast Worm |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.024
|
Yeast |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.024
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.024
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.024
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.024
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.024
|
Yeast |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.024
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.024
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.023
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.023
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.023
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.023
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.023
|
Yeast |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.023
|
Yeast |
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.023
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.023
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.023
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.022
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.022
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.022
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.022
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.022
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.022
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.022
|
Human |
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.022
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.022
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.021
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.021
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.021
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.021
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.021
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.021
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.021
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.021
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.021
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.021
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.021
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.020
|
Fly |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.020
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.020
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.020
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.020
|
Fly |
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.020
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
4 |
0.020
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.020
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.020
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.020
|
Yeast |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.020
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.019
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.019
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.019
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.019
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.019
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.019
|
Human |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.019
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.019
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.019
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.019
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.019
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.019
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.019
|
Human |
|
|
signal release
|
GO:0023061 |
70 |
0.019
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.019
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.019
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.019
|
Yeast |
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.019
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.019
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.019
|
Fly |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.018
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.018
|
Fly |
|
|
hormone secretion
|
GO:0046879 |
65 |
0.018
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.018
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.018
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.018
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.018
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.018
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.018
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.018
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.018
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.018
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.018
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.018
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.018
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.018
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.018
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.018
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.018
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.018
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.018
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.017
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.017
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.017
|
Fly |
|
|
spermatid development
|
GO:0007286 |
4 |
0.017
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.017
|
Fly |
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.017
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.017
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.017
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.017
|
Human |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.017
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.017
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.017
|
Worm |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.017
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.017
|
Worm |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.017
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.017
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.017
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.017
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.016
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.016
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.016
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.016
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.016
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.016
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.016
|
Worm |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.016
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.016
|
Worm |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.016
|
|
|
|
aging
|
GO:0007568 |
66 |
0.016
|
Worm |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.016
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.016
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.016
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.016
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.016
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.016
|
Yeast |
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.016
|
Yeast |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.016
|
|
|
|
growth
|
GO:0040007 |
202 |
0.016
|
Human |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.016
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.016
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.016
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.015
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.015
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.015
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.015
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.015
|
Yeast |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.015
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.015
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.015
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.015
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.015
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.015
|
Yeast |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.015
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.015
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.015
|
Human |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.015
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.015
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.015
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.015
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.015
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.014
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.014
|
Human |
|
|
neuron development
|
GO:0048666 |
113 |
0.014
|
Fly |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.014
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.014
|
Yeast |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.014
|
Worm |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.014
|
Worm |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.014
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.014
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.014
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.014
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.014
|
Yeast Worm Fly |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.014
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.014
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.014
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.014
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.014
|
Worm |
|
|
double strand break repair
|
GO:0006302 |
101 |
0.014
|
|
|
|
mrna catabolic process
|
GO:0006402 |
56 |
0.014
|
Human |
|
|
protein folding
|
GO:0006457 |
38 |
0.014
|
|
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.014
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.014
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.014
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.014
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.014
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.014
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.014
|
Fly |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.013
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.013
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
4 |
0.013
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.013
|
|
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
0.013
|
Yeast |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.013
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.013
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.013
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.013
|
Worm |
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.013
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.013
|
|
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.013
|
Yeast |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.013
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.013
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.013
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.013
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.013
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.013
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.013
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.013
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.013
|
Human |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.013
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.013
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.013
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.013
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.013
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.013
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.013
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.013
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.013
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.013
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.013
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.013
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.013
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.013
|
Human |
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.013
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.013
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.013
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.013
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.013
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.013
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.013
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.013
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.013
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.013
|
Worm Fly |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.013
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.013
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.013
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.013
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.013
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.012
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.012
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.012
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.012
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.012
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.012
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.012
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.012
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.012
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.012
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.012
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.012
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.012
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.012
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.012
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.012
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.012
|
|
