Homo sapiens

120 known processes

RTEL1

regulator of telomere elongation helicase 1

(Aliases: RTEL,NHL,C20orf41,bK3184A7.3,KIAA1088,DKFZp434C013)

RTEL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.077
carbohydrate derivative biosynthetic process GO:1901137 207 0.074
ribonucleoside triphosphate metabolic process GO:0009199 412 0.074
nucleoside triphosphate metabolic process GO:0009141 422 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.067
purine ribonucleoside metabolic process GO:0046128 437 0.065
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.062
purine containing compound catabolic process GO:0072523 411 0.061
purine ribonucleotide catabolic process GO:0009154 404 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.057
organonitrogen compound biosynthetic process GO:1901566 200 0.052
purine nucleoside triphosphate catabolic process GO:0009146 392 0.052
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.052
nucleoside catabolic process GO:0009164 408 0.051
oogenesis GO:0048477 2 0.051
purine ribonucleoside catabolic process GO:0046130 398 0.049
organophosphate catabolic process GO:0046434 430 0.049
positive regulation of catabolic process GO:0009896 310 0.049
nucleotide catabolic process GO:0009166 408 0.048
cell development GO:0048468 328 0.047
purine nucleoside triphosphate metabolic process GO:0009144 412 0.046
positive regulation of nucleotide catabolic process GO:0030813 185 0.046
purine nucleoside catabolic process GO:0006152 398 0.045
nucleoside phosphate catabolic process GO:1901292 412 0.045
membrane organization GO:0061024 292 0.045
purine nucleotide catabolic process GO:0006195 405 0.045
nucleoside triphosphate catabolic process GO:0009143 394 0.044
small gtpase mediated signal transduction GO:0007264 78 0.043
positive regulation of hydrolase activity GO:0051345 331 0.042
glycosyl compound catabolic process GO:1901658 413 0.042
regulation of gtp catabolic process GO:0033124 180 0.042
positive regulation of cellular catabolic process GO:0031331 284 0.041
cellular macromolecule catabolic process GO:0044265 380 0.041
cell morphogenesis GO:0000902 296 0.041
cellular response to dna damage stimulus GO:0006974 379 0.040
determination of adult lifespan GO:0008340 2 0.039
gtp catabolic process GO:0006184 237 0.038
cellular amino acid metabolic process GO:0006520 116 0.038
regulation of nucleotide metabolic process GO:0006140 269 0.038
mitotic cell cycle GO:0000278 326 0.037
positive regulation of nucleotide metabolic process GO:0045981 230 0.037
cell projection organization GO:0030030 252 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.036
apoptotic signaling pathway GO:0097190 268 0.036
positive regulation of apoptotic process GO:0043065 246 0.035
negative regulation of cell death GO:0060548 345 0.035
ribonucleoside catabolic process GO:0042454 406 0.034
female gamete generation GO:0007292 2 0.033
regulation of cell cycle GO:0051726 393 0.033
positive regulation of nucleoside metabolic process GO:0045979 186 0.032
positive regulation of gtp catabolic process GO:0033126 166 0.032
multicellular organismal aging GO:0010259 3 0.031
single organism cellular localization GO:1902580 332 0.030
vesicle mediated transport GO:0016192 371 0.030
segmentation GO:0035282 4 0.029
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
regulation of nucleoside metabolic process GO:0009118 209 0.029
guanosine containing compound metabolic process GO:1901068 244 0.028
cellular amine metabolic process GO:0044106 41 0.028
amine metabolic process GO:0009308 44 0.028
dephosphorylation GO:0016311 209 0.028
actin filament based process GO:0030029 224 0.026
neuromuscular junction development GO:0007528 3 0.026
epithelium migration GO:0090132 119 0.026
negative regulation of cell cycle GO:0045786 193 0.026
single organism membrane organization GO:0044802 268 0.026
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
negative regulation of apoptotic process GO:0043066 316 0.026
positive regulation of transferase activity GO:0051347 227 0.026
establishment of protein localization to membrane GO:0090150 121 0.026
oocyte differentiation GO:0009994 2 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
protein catabolic process GO:0030163 325 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
cellular response to cytokine stimulus GO:0071345 181 0.024
ribonucleotide catabolic process GO:0009261 405 0.024
positive regulation of cell death GO:0010942 263 0.024
protein localization to membrane GO:0072657 160 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
cell growth GO:0016049 160 0.023
cellular ketone metabolic process GO:0042180 80 0.023
response to abiotic stimulus GO:0009628 336 0.023
regulation of kinase activity GO:0043549 314 0.023
rho protein signal transduction GO:0007266 26 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
regulation of ras protein signal transduction GO:0046578 155 0.023
immune response GO:0006955 307 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
epithelial cell migration GO:0010631 119 0.022
regulation of transferase activity GO:0051338 355 0.022
gtp metabolic process GO:0046039 239 0.022
rna processing GO:0006396 255 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
tissue migration GO:0090130 119 0.021
regulation of gtpase activity GO:0043087 180 0.021
cell projection morphogenesis GO:0048858 129 0.021
oocyte development GO:0048599 1 0.021
regulation of protein localization GO:0032880 296 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
regulation of cellular response to stress GO:0080135 244 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
regulation of proteolysis GO:0030162 293 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
ameboidal type cell migration GO:0001667 135 0.020
growth GO:0040007 202 0.020
ras protein signal transduction GO:0007265 73 0.020
regulation of phosphatase activity GO:0010921 81 0.020
positive regulation of immune system process GO:0002684 283 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
cell cycle phase transition GO:0044770 173 0.019
regulation of dephosphorylation GO:0035303 96 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
biological adhesion GO:0022610 331 0.019
regulation of cell differentiation GO:0045595 393 0.019
positive regulation of phosphorylation GO:0042327 394 0.018
cellular component morphogenesis GO:0032989 314 0.018
nervous system development GO:0007399 293 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
nucleoside phosphate biosynthetic process GO:1901293 109 0.018
cytoplasmic transport GO:0016482 379 0.018
positive regulation of gtpase activity GO:0043547 166 0.018
spermatid development GO:0007286 4 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
plasma membrane organization GO:0007009 115 0.018
cell cycle checkpoint GO:0000075 117 0.017
microtubule based process GO:0007017 210 0.017
blastoderm segmentation GO:0007350 2 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
protein localization to organelle GO:0033365 280 0.017
negative regulation of developmental process GO:0051093 247 0.017
organelle fission GO:0048285 149 0.017
macromolecule methylation GO:0043414 97 0.017
peptidyl tyrosine modification GO:0018212 170 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
intracellular protein transport GO:0006886 270 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
regulation of response to external stimulus GO:0032101 222 0.017
regulation of cell migration GO:0030334 289 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
locomotory behavior GO:0007626 1 0.017
covalent chromatin modification GO:0016569 254 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
dna replication GO:0006260 116 0.016
neurogenesis GO:0022008 169 0.016
regulation of cellular component size GO:0032535 82 0.016
response to oxidative stress GO:0006979 121 0.016
cell adhesion GO:0007155 325 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
glycoprotein metabolic process GO:0009100 110 0.016
positive regulation of ras gtpase activity GO:0032320 117 0.016
memory GO:0007613 3 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
spermatid differentiation GO:0048515 4 0.016
organ formation GO:0048645 3 0.016
protein maturation GO:0051604 233 0.015
mapk cascade GO:0000165 288 0.015
purine nucleotide biosynthetic process GO:0006164 84 0.015
regulation of rho protein signal transduction GO:0035023 79 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
ribonucleotide biosynthetic process GO:0009260 81 0.015
response to radiation GO:0009314 151 0.015
response to cytokine GO:0034097 232 0.015
anterior posterior axis specification GO:0009948 2 0.015
protein localization to plasma membrane GO:0072659 93 0.015
actin cytoskeleton organization GO:0030036 207 0.015
regulation of cell cycle process GO:0010564 266 0.015
regulation of cell motility GO:2000145 299 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
endomembrane system organization GO:0010256 196 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.015
atp metabolic process GO:0046034 176 0.015
response to inorganic substance GO:0010035 127 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.014
mitotic cell cycle process GO:1903047 286 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
blood vessel morphogenesis GO:0048514 162 0.014
purine containing compound biosynthetic process GO:0072522 88 0.014
positive regulation of proteolysis GO:0045862 142 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
negative regulation of phosphatase activity GO:0010923 61 0.014
cell projection assembly GO:0030031 126 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
purine ribonucleotide biosynthetic process GO:0009152 79 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
regulation of protein kinase activity GO:0045859 289 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
positive regulation of developmental process GO:0051094 314 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of locomotion GO:0040012 329 0.014
cell part morphogenesis GO:0032990 137 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
defense response GO:0006952 315 0.014
cellular protein catabolic process GO:0044257 261 0.014
regulation of mitotic cell cycle GO:0007346 189 0.013
protein ubiquitination GO:0016567 314 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
positive regulation of transport GO:0051050 336 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
neurotransmitter secretion GO:0007269 4 0.013
cellular homeostasis GO:0019725 196 0.013
cell activation GO:0001775 213 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
positive regulation of organelle organization GO:0010638 195 0.013
regulation of rho gtpase activity GO:0032319 66 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
regulation of vasculature development GO:1901342 97 0.013
glycoprotein biosynthetic process GO:0009101 91 0.012
mitochondrion organization GO:0007005 156 0.012
activation of protein kinase activity GO:0032147 90 0.012
histone modification GO:0016570 251 0.012
hemopoiesis GO:0030097 180 0.012
response to uv GO:0009411 73 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.012
cell morphogenesis involved in differentiation GO:0000904 144 0.012
protein processing GO:0016485 226 0.012
positive regulation of kinase activity GO:0033674 204 0.012
nitrogen compound transport GO:0071705 191 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
cilium assembly GO:0042384 63 0.012
regulation of angiogenesis GO:0045765 92 0.012
regulation of intracellular transport GO:0032386 195 0.012
protein oligomerization GO:0051259 173 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
cilium morphogenesis GO:0060271 75 0.012
nuclear division GO:0000280 128 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
single organism reproductive process GO:0044702 98 0.012
meiosis i GO:0007127 4 0.012
epithelium development GO:0060429 227 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
chromosome segregation GO:0007059 114 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
actin filament organization GO:0007015 128 0.011
golgi vesicle transport GO:0048193 80 0.011
cellular protein complex assembly GO:0043623 188 0.011
regulation of anatomical structure size GO:0090066 101 0.011
vasculature development GO:0001944 181 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
neuron differentiation GO:0030182 138 0.011
regulation of epithelial cell migration GO:0010632 93 0.011
endothelial cell migration GO:0043542 86 0.011
regulation of multi organism process GO:0043900 157 0.011
developmental process involved in reproduction GO:0003006 66 0.011
protein modification by small protein conjugation GO:0032446 342 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
response to external biotic stimulus GO:0043207 261 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
regulation of protein transport GO:0051223 213 0.011
organelle assembly GO:0070925 176 0.011
positive regulation of cellular component movement GO:0051272 181 0.010
response to oxygen containing compound GO:1901700 369 0.010
endocytosis GO:0006897 159 0.010
regulation of microtubule based process GO:0032886 74 0.010
associative learning GO:0008306 1 0.010
embryonic viscerocranium morphogenesis GO:0048703 1 0.010
regulation of protein catabolic process GO:0042176 155 0.010
regulation of immune response GO:0050776 201 0.010
negative regulation of dephosphorylation GO:0035305 63 0.010
regulation of mapk cascade GO:0043408 262 0.010
response to other organism GO:0051707 261 0.010
blood vessel development GO:0001568 172 0.010
meiotic chromosome segregation GO:0045132 4 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
peptidyl serine modification GO:0018209 106 0.010

RTEL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
organ system cancer DOID:0050686 164 0.016
bone disease DOID:0080001 88 0.015
musculoskeletal system disease DOID:17 223 0.015
connective tissue disease DOID:65 109 0.015
central nervous system disease DOID:331 186 0.013
nervous system disease DOID:863 431 0.013
sensory system disease DOID:0050155 203 0.011
disease of metabolism DOID:0014667 295 0.011