Homo sapiens

12 known processes

SCN4A

sodium channel, voltage-gated, type IV, alpha subunit

(Aliases: NAC1A,Nav1.4,Na(V)1.4,HYKPP,HOKPP2,HYPP,SkM1)

SCN4A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle system process GO:0003012 81 0.452
Human
muscle contraction GO:0006936 73 0.397
Human
ion transmembrane transport GO:0034220 338 0.376
Human
system process GO:0003008 349 0.365
Human
transmembrane transport GO:0055085 399 0.310
Human
inorganic ion transmembrane transport GO:0098660 231 0.300
Human
cation transmembrane transport GO:0098655 238 0.246
Human
cation transport GO:0006812 331 0.232
Human Rat
cellular response to endogenous stimulus GO:0071495 336 0.226
cellular amine metabolic process GO:0044106 41 0.216
blood circulation GO:0008015 113 0.209
Human
regulation of ion transmembrane transport GO:0034765 132 0.173
Human
regulation of cellular amine metabolic process GO:0033238 11 0.160
amine metabolic process GO:0009308 44 0.158
regulation of cellular ketone metabolic process GO:0010565 50 0.142
regulation of ion transport GO:0043269 189 0.136
Human
metal ion transport GO:0030001 272 0.124
Human Rat
cellular ketone metabolic process GO:0042180 80 0.123
regulation of cellular amino acid metabolic process GO:0006521 6 0.123
heart contraction GO:0060047 62 0.123
Human
striated muscle contraction GO:0006941 52 0.120
Human
response to oxygen containing compound GO:1901700 369 0.118
regulation of transmembrane transport GO:0034762 139 0.116
Human
circulatory system process GO:0003013 113 0.102
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.100
regulation of system process GO:0044057 101 0.094
Human
chemical homeostasis GO:0048878 306 0.094
Human
cell development GO:0048468 328 0.089
actin filament based movement GO:0030048 17 0.086
cellular amino acid metabolic process GO:0006520 116 0.083
mapk cascade GO:0000165 288 0.082
heart process GO:0003015 62 0.080
Human
inorganic cation transmembrane transport GO:0098662 194 0.079
Human
secretion GO:0046903 254 0.078
cellular chemical homeostasis GO:0055082 180 0.074
ion homeostasis GO:0050801 230 0.073
Human
monovalent inorganic cation transport GO:0015672 128 0.072
Human Rat
circulatory system development GO:0072359 262 0.071
biological adhesion GO:0022610 331 0.070
response to abiotic stimulus GO:0009628 336 0.065
positive regulation of cellular amine metabolic process GO:0033240 7 0.063
calcium ion transport GO:0006816 147 0.061
cellular homeostasis GO:0019725 196 0.059
cardiovascular system development GO:0072358 262 0.058
muscle structure development GO:0061061 98 0.056
regulation of cellular component biogenesis GO:0044087 281 0.055
post embryonic development GO:0009791 2 0.055
cellular component morphogenesis GO:0032989 314 0.055
cell cell signaling GO:0007267 155 0.055
signal transduction by phosphorylation GO:0023014 297 0.053
negative regulation of multicellular organismal process GO:0051241 317 0.053
purine containing compound catabolic process GO:0072523 411 0.052
divalent metal ion transport GO:0070838 152 0.052
cellular response to organic cyclic compound GO:0071407 127 0.052
positive regulation of cellular component organization GO:0051130 376 0.052
positive regulation of developmental process GO:0051094 314 0.052
cellular ion homeostasis GO:0006873 168 0.052
negative regulation of protein metabolic process GO:0051248 391 0.051
organonitrogen compound biosynthetic process GO:1901566 200 0.051
negative regulation of cellular protein metabolic process GO:0032269 353 0.051
regulation of muscle system process GO:0090257 53 0.050
Human
regulation of muscle contraction GO:0006937 45 0.050
Human
cation homeostasis GO:0055080 189 0.050
organ morphogenesis GO:0009887 147 0.050
negative regulation of transport GO:0051051 176 0.049
negative regulation of phosphorus metabolic process GO:0010563 267 0.049
striated muscle tissue development GO:0014706 59 0.048
regulation of cellular component movement GO:0051270 334 0.048
anatomical structure formation involved in morphogenesis GO:0048646 284 0.048
positive regulation of phosphorylation GO:0042327 394 0.048
cyclic nucleotide metabolic process GO:0009187 82 0.047
negative regulation of catalytic activity GO:0043086 335 0.047
cellular response to nitrogen compound GO:1901699 144 0.046
regulation of metal ion transport GO:0010959 120 0.046
neurological system process GO:0050877 163 0.046
regulation of blood circulation GO:1903522 59 0.046
Human
nucleoside phosphate catabolic process GO:1901292 412 0.045
regulation of transferase activity GO:0051338 355 0.045
single organism cellular localization GO:1902580 332 0.045
multicellular organismal aging GO:0010259 3 0.045
cardiac muscle contraction GO:0060048 34 0.045
Human
regulation of hormone levels GO:0010817 125 0.045
regulation of cell differentiation GO:0045595 393 0.045
ribonucleoside catabolic process GO:0042454 406 0.044
cellular cation homeostasis GO:0030003 163 0.044
intracellular protein transport GO:0006886 270 0.044
carbohydrate derivative biosynthetic process GO:1901137 207 0.044
actin mediated cell contraction GO:0070252 12 0.044
response to hormone GO:0009725 175 0.043
secretion by cell GO:0032940 226 0.043
response to organonitrogen compound GO:0010243 156 0.043
segmentation GO:0035282 4 0.042
regulation of mapk cascade GO:0043408 262 0.042
divalent inorganic cation transport GO:0072511 158 0.041
immune response GO:0006955 307 0.041
heart development GO:0007507 95 0.041
nervous system development GO:0007399 293 0.041
regulation of heart rate GO:0002027 38 0.041
Human
protein localization to organelle GO:0033365 280 0.041
nitrogen compound transport GO:0071705 191 0.041
Rat
cell adhesion GO:0007155 325 0.041
heart morphogenesis GO:0003007 48 0.041
response to nitrogen compound GO:1901698 184 0.040
metal ion homeostasis GO:0055065 169 0.040
cellular response to organonitrogen compound GO:0071417 124 0.040
divalent inorganic cation homeostasis GO:0072507 136 0.040
membrane organization GO:0061024 292 0.039
cardiac muscle cell contraction GO:0086003 4 0.039
nucleoside phosphate biosynthetic process GO:1901293 109 0.039
regulation of secretion by cell GO:1903530 177 0.039
cell morphogenesis GO:0000902 296 0.038
cytoplasmic transport GO:0016482 379 0.038
regulation of locomotion GO:0040012 329 0.038
actin filament based process GO:0030029 224 0.037
hindbrain development GO:0030902 3 0.037
g protein coupled receptor signaling pathway GO:0007186 207 0.037
negative regulation of cellular amine metabolic process GO:0033239 3 0.037
purine ribonucleoside catabolic process GO:0046130 398 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
nucleoside catabolic process GO:0009164 408 0.036
locomotory behavior GO:0007626 1 0.036
purine nucleoside triphosphate catabolic process GO:0009146 392 0.036
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.036
muscle tissue development GO:0060537 62 0.036
regulation of cell cycle GO:0051726 393 0.036
positive regulation of transport GO:0051050 336 0.036
organophosphate biosynthetic process GO:0090407 163 0.036
determination of adult lifespan GO:0008340 2 0.036
ras protein signal transduction GO:0007265 73 0.035
single organism membrane organization GO:0044802 268 0.035
ribonucleoside triphosphate catabolic process GO:0009203 391 0.035
regulation of proteolysis GO:0030162 293 0.035
organophosphate catabolic process GO:0046434 430 0.035
regulation of nucleotide metabolic process GO:0006140 269 0.035
cellular response to oxygen containing compound GO:1901701 276 0.035
regulation of kinase activity GO:0043549 314 0.034
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.034
ribonucleotide catabolic process GO:0009261 405 0.034
cellular calcium ion homeostasis GO:0006874 117 0.033
purine ribonucleotide catabolic process GO:0009154 404 0.033
regulation of protein transport GO:0051223 213 0.033
response to organic cyclic compound GO:0014070 204 0.033
cellular divalent inorganic cation homeostasis GO:0072503 128 0.033
positive regulation of catabolic process GO:0009896 310 0.033
regulation of protein kinase activity GO:0045859 289 0.033
ribonucleoside monophosphate metabolic process GO:0009161 187 0.033
negative regulation of phosphate metabolic process GO:0045936 267 0.032
positive regulation of cell death GO:0010942 263 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
positive regulation of cell proliferation GO:0008284 301 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
regulation of membrane potential GO:0042391 95 0.032
Human
response to lipid GO:0033993 206 0.032
oogenesis GO:0048477 2 0.032
mitotic cell cycle GO:0000278 326 0.032
regulation of secretion GO:0051046 194 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
negative regulation of developmental process GO:0051093 247 0.031
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.031
regulation of ion transmembrane transporter activity GO:0032412 72 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
neuromuscular junction development GO:0007528 3 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
female gamete generation GO:0007292 2 0.031
positive regulation of transferase activity GO:0051347 227 0.031
cyclic nucleotide biosynthetic process GO:0009190 61 0.031
regulation of cell motility GO:2000145 299 0.031
sodium ion transmembrane transport GO:0035725 59 0.031
Human
regulation of calcium ion transport GO:0051924 79 0.031
regulation of intracellular transport GO:0032386 195 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
purine nucleoside catabolic process GO:0006152 398 0.031
cytosolic calcium ion homeostasis GO:0051480 89 0.030
cardiac muscle tissue development GO:0048738 39 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.030
response to growth factor GO:0070848 205 0.030
anion transport GO:0006820 161 0.030
purine ribonucleotide biosynthetic process GO:0009152 79 0.030
sensory perception GO:0007600 103 0.030
purine nucleoside monophosphate catabolic process GO:0009128 158 0.030
positive regulation of cell differentiation GO:0045597 211 0.029
regulation of cytokine production GO:0001817 232 0.029
cellular response to hormone stimulus GO:0032870 125 0.029
negative regulation of protein modification process GO:0031400 200 0.029
regulation of cell cycle process GO:0010564 266 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
regulation of transmembrane transporter activity GO:0022898 74 0.029
calcium ion homeostasis GO:0055074 122 0.029
positive regulation of immune system process GO:0002684 283 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
single organism carbohydrate metabolic process GO:0044723 193 0.029
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.029
protein oligomerization GO:0051259 173 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.029
response to external biotic stimulus GO:0043207 261 0.029
vesicle mediated transport GO:0016192 371 0.029
nerve development GO:0021675 4 0.028
nucleoside monophosphate metabolic process GO:0009123 191 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
peptidyl serine phosphorylation GO:0018105 101 0.028
purine nucleoside monophosphate metabolic process GO:0009126 186 0.028
calcium ion transmembrane transport GO:0070588 76 0.028
reactive oxygen species metabolic process GO:0072593 75 0.028
regulation of actin filament based process GO:0032970 141 0.028
regulation of protein localization GO:0032880 296 0.028
organic hydroxy compound transport GO:0015850 63 0.028
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
reactive nitrogen species metabolic process GO:2001057 3 0.028
ossification GO:0001503 121 0.028
positive regulation of organelle organization GO:0010638 195 0.027
second messenger mediated signaling GO:0019932 78 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
ribonucleotide biosynthetic process GO:0009260 81 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.027
response to other organism GO:0051707 261 0.027
potassium ion transmembrane transport GO:0071805 60 0.027
cyclic purine nucleotide metabolic process GO:0052652 60 0.027
response to biotic stimulus GO:0009607 276 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.027
response to radiation GO:0009314 151 0.027
oxidation reduction process GO:0055114 396 0.026
glycosyl compound catabolic process GO:1901658 413 0.026
cytokine production GO:0001816 247 0.026
purine containing compound biosynthetic process GO:0072522 88 0.026
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.026
ribose phosphate biosynthetic process GO:0046390 82 0.026
anterior posterior axis specification GO:0009948 2 0.026
purine nucleotide biosynthetic process GO:0006164 84 0.026
reactive oxygen species biosynthetic process GO:1903409 4 0.026
negative regulation of cell death GO:0060548 345 0.026
regulation of transporter activity GO:0032409 82 0.026
regeneration GO:0031099 4 0.026
positive regulation of cellular component biogenesis GO:0044089 158 0.026
regulation of protein serine threonine kinase activity GO:0071900 179 0.025
protein targeting GO:0006605 187 0.025
carbohydrate metabolic process GO:0005975 207 0.025
cellular lipid metabolic process GO:0044255 303 0.025
regulation of cell migration GO:0030334 289 0.025
regulation of growth GO:0040008 165 0.025
cellular potassium ion transport GO:0071804 60 0.025
protein catabolic process GO:0030163 325 0.024
cellular metal ion homeostasis GO:0006875 146 0.024
chromatin organization GO:0006325 351 0.024
regulation of synaptic plasticity GO:0048167 3 0.024
camp metabolic process GO:0046058 61 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
atp metabolic process GO:0046034 176 0.024
immune system development GO:0002520 195 0.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.024
dephosphorylation GO:0016311 209 0.024
positive regulation of cytokine production GO:0001819 167 0.024
nucleotide catabolic process GO:0009166 408 0.024
positive regulation of cell cycle GO:0045787 140 0.024
negative regulation of immune system process GO:0002683 136 0.024
mitotic cell cycle process GO:1903047 286 0.024
circadian behavior GO:0048512 2 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.023
potassium ion transport GO:0006813 62 0.023
Rat
negative regulation of secretion GO:0051048 58 0.023
positive regulation of secretion by cell GO:1903532 108 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
protein localization to nucleus GO:0034504 136 0.023
nucleotide biosynthetic process GO:0009165 109 0.023
regulation of multi organism process GO:0043900 157 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
positive regulation of hydrolase activity GO:0051345 331 0.022
covalent chromatin modification GO:0016569 254 0.022
blastoderm segmentation GO:0007350 2 0.022
maintenance of location GO:0051235 112 0.022
regulation of camp biosynthetic process GO:0030817 45 0.022
epithelium development GO:0060429 227 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
regulation of reactive oxygen species metabolic process GO:2000377 41 0.022
peptidyl serine modification GO:0018209 106 0.022
nuclear transport GO:0051169 179 0.022
positive regulation of ion transport GO:0043270 87 0.022
rho protein signal transduction GO:0007266 26 0.021
histone modification GO:0016570 251 0.021
protein homooligomerization GO:0051260 100 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
multicellular organismal response to stress GO:0033555 1 0.021
lipid metabolic process GO:0006629 381 0.021
cell division GO:0051301 168 0.021
blood vessel development GO:0001568 172 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
hair follicle morphogenesis GO:0031069 2 0.021
growth GO:0040007 202 0.020
nucleoside monophosphate catabolic process GO:0009125 159 0.020
regulation of heart contraction GO:0008016 50 0.020
Human
regulation of cytoplasmic transport GO:1903649 149 0.020
signal release GO:0023061 70 0.020
regulation of lipid metabolic process GO:0019216 96 0.020
negative regulation of cell proliferation GO:0008285 228 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
positive regulation of cell cycle process GO:0090068 106 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
organelle assembly GO:0070925 176 0.020
action potential GO:0001508 34 0.020
rhythmic behavior GO:0007622 2 0.020
positive regulation of secretion GO:0051047 116 0.020
positive regulation of kinase activity GO:0033674 204 0.020
hemopoiesis GO:0030097 180 0.019
response to light stimulus GO:0009416 87 0.019
sequestering of calcium ion GO:0051208 17 0.019
cell activation GO:0001775 213 0.019
skeletal system development GO:0001501 79 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
adult locomotory behavior GO:0008344 1 0.019
regulation of cellular response to stress GO:0080135 244 0.019
negative regulation of growth GO:0045926 97 0.019
cell growth GO:0016049 160 0.019
camp biosynthetic process GO:0006171 47 0.019
regulation of protein catabolic process GO:0042176 155 0.019
regulation of striated muscle contraction GO:0006942 37 0.019
Human
organic acid transport GO:0015849 65 0.019
stem cell differentiation GO:0048863 93 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.019
syncytium formation by plasma membrane fusion GO:0000768 2 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
cerebellum development GO:0021549 2 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
detection of stimulus GO:0051606 85 0.018
response to disaccharide GO:0034285 1 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
response to sucrose GO:0009744 1 0.018
somatic muscle development GO:0007525 1 0.018
anterior posterior axis specification embryo GO:0008595 2 0.018
positive regulation of cell motility GO:2000147 177 0.018
regulation of protein complex assembly GO:0043254 147 0.018
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
regulation of cardiac muscle contraction GO:0055117 33 0.018
Human
cellular response to dna damage stimulus GO:0006974 379 0.018
atp catabolic process GO:0006200 157 0.018
response to decreased oxygen levels GO:0036293 96 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
memory GO:0007613 3 0.018
startle response GO:0001964 3 0.018
cellular protein catabolic process GO:0044257 261 0.017
cell projection organization GO:0030030 252 0.017
protein localization to membrane GO:0072657 160 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
central nervous system development GO:0007417 123 0.017
rna processing GO:0006396 255 0.017
cardiac chamber morphogenesis GO:0003206 26 0.017
atrial cardiac muscle tissue morphogenesis GO:0055009 1 0.017
negative regulation of secretion by cell GO:1903531 52 0.017
gamma aminobutyric acid signaling pathway GO:0007214 3 0.017
regulation of chromosome organization GO:0033044 103 0.017
cell substrate adhesion GO:0031589 132 0.017
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.017
establishment of protein localization to organelle GO:0072594 172 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.017
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.017
tripartite regional subdivision GO:0007351 2 0.017
regulation of protein secretion GO:0050708 86 0.017
regulation of cell adhesion GO:0030155 166 0.017
oocyte differentiation GO:0009994 2 0.017
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.017
hormone secretion GO:0046879 65 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
negative regulation of synaptic transmission GO:0050805 2 0.016
response to cytokine GO:0034097 232 0.016
protein ubiquitination GO:0016567 314 0.016
protein maturation GO:0051604 233 0.016
positive regulation of hormone biosynthetic process GO:0046886 4 0.016
hormone transport GO:0009914 68 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
muscle organ morphogenesis GO:0048644 19 0.016
wound healing GO:0042060 115 0.016
metencephalon development GO:0022037 2 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
cell cycle phase transition GO:0044770 173 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
negative regulation of organelle organization GO:0010639 126 0.016
oocyte development GO:0048599 1 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
defense response GO:0006952 315 0.016
sensory perception of pain GO:0019233 4 0.016
response to activity GO:0014823 0 0.016
synaptic transmission GO:0007268 61 0.016
amide transport GO:0042886 76 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
leukocyte migration GO:0050900 107 0.016
positive regulation of proteolysis GO:0045862 142 0.016
neurogenesis GO:0022008 169 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.015
regulation of dna metabolic process GO:0051052 153 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of homeostatic process GO:0032844 121 0.015
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.015
response to virus GO:0009615 126 0.015
immune effector process GO:0002252 159 0.015
positive regulation of cellular component movement GO:0051272 181 0.015
muscle cell differentiation GO:0042692 63 0.015
response to fungus GO:0009620 4 0.015
positive regulation of protein transport GO:0051222 135 0.015
renal system development GO:0072001 63 0.015
negative regulation of catabolic process GO:0009895 104 0.015
tissue morphogenesis GO:0048729 96 0.015
aortic valve development GO:0003176 3 0.015
endomembrane system organization GO:0010256 196 0.015
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.015
response to wounding GO:0009611 168 0.015
inorganic anion transport GO:0015698 60 0.015
regulation of response to external stimulus GO:0032101 222 0.015
regulation of cell growth GO:0001558 135 0.015
response to transforming growth factor beta GO:0071559 94 0.015
apoptotic signaling pathway GO:0097190 268 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
negative regulation of cell cycle GO:0045786 193 0.015
osteoblast differentiation GO:0001649 92 0.015
regulation of carbohydrate metabolic process GO:0006109 54 0.015
myeloid cell differentiation GO:0030099 117 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
blood vessel morphogenesis GO:0048514 162 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
tissue regeneration GO:0042246 3 0.014
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.014
organic anion transport GO:0015711 103 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
negative regulation of transferase activity GO:0051348 124 0.014
cell part morphogenesis GO:0032990 137 0.014
regulation of camp metabolic process GO:0030814 52 0.014
multicellular organismal signaling GO:0035637 34 0.014
Human
positive regulation of cell migration GO:0030335 172 0.014
carboxylic acid transport GO:0046942 63 0.014
cranial nerve development GO:0021545 4 0.014
regulation of cell activation GO:0050865 125 0.014
anion transmembrane transport GO:0098656 76 0.014
positive regulation of camp biosynthetic process GO:0030819 35 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.014
skeletal muscle contraction GO:0003009 16 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
organelle fission GO:0048285 149 0.014
brain development GO:0007420 97 0.014
mitochondrion organization GO:0007005 156 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
cellular protein complex assembly GO:0043623 188 0.014
cellular response to lipid GO:0071396 127 0.014
post embryonic organ development GO:0048569 1 0.014
positive regulation of locomotion GO:0040017 186 0.014
negative regulation of ion transport GO:0043271 39 0.014
vasculature development GO:0001944 181 0.014
sequestering of metal ion GO:0051238 24 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
spermatid development GO:0007286 4 0.013
generation of neurons GO:0048699 152 0.013
small molecule biosynthetic process GO:0044283 157 0.013
protein acylation GO:0043543 138 0.013
regulation of calcium ion transmembrane transport GO:1903169 28 0.013
response to peptide GO:1901652 65 0.013
positive regulation of lipid metabolic process GO:0045834 50 0.013
regulation of acrosome reaction GO:0060046 4 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.013
visual behavior GO:0007632 2 0.013
response to inorganic substance GO:0010035 127 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
organ formation GO:0048645 3 0.013
motor neuron axon guidance GO:0008045 2 0.013
lipid biosynthetic process GO:0008610 177 0.013

SCN4A disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.232
myopathy DOID:423 104 0.197
muscular disease DOID:0080000 114 0.197
muscle tissue disease DOID:66 113 0.197
cardiovascular system disease DOID:1287 106 0.123
sensory system disease DOID:0050155 203 0.053
nervous system disease DOID:863 431 0.053
Human
retinal disease DOID:5679 118 0.029
eye and adnexa disease DOID:1492 150 0.029
eye disease DOID:5614 149 0.029
heart disease DOID:114 68 0.028
cardiomyopathy DOID:0050700 50 0.028
intrinsic cardiomyopathy DOID:0060036 50 0.028
disease of metabolism DOID:0014667 295 0.020
central nervous system disease DOID:331 186 0.020
Human
inherited metabolic disorder DOID:655 242 0.019
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
organ system cancer DOID:0050686 164 0.014
neurodegenerative disease DOID:1289 102 0.014