Homo sapiens

64 known processes

BRIP1

BRCA1 interacting protein C-terminal helicase 1

(Aliases: FLJ90232,OF,BACH1,MGC126523,MGC126521,FANCJ)

BRIP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna recombination GO:0006310 77 0.922
cellular response to dna damage stimulus GO:0006974 379 0.894
Worm
double strand break repair via homologous recombination GO:0000724 50 0.890
dna repair GO:0006281 198 0.854
Worm
meiotic chromosome separation GO:0051307 3 0.785
mismatch repair GO:0006298 15 0.689
somatic diversification of immune receptors via somatic mutation GO:0002566 1 0.687
double strand break repair GO:0006302 101 0.641
somatic hypermutation of immunoglobulin genes GO:0016446 1 0.610
double strand break repair via single strand annealing GO:0045002 4 0.603
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.560
recombinational repair GO:0000725 50 0.511
nuclear division GO:0000280 128 0.486
Worm
meiosis i GO:0007127 4 0.477
g2 dna damage checkpoint GO:0031572 26 0.448
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.423
meiotic cell cycle GO:0051321 13 0.336
Worm
male meiosis GO:0007140 1 0.329
chromosome segregation GO:0007059 114 0.320
Worm
organelle fission GO:0048285 149 0.316
Worm
non recombinational repair GO:0000726 14 0.313
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.310
immune system development GO:0002520 195 0.308
isotype switching GO:0045190 3 0.293
ribonucleoside triphosphate catabolic process GO:0009203 391 0.279
ribonucleoside monophosphate catabolic process GO:0009158 158 0.264
dna double strand break processing GO:0000729 10 0.258
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.247
dna synthesis involved in dna repair GO:0000731 6 0.246
nucleoside triphosphate catabolic process GO:0009143 394 0.246
purine containing compound catabolic process GO:0072523 411 0.241
regulation of double strand break repair via homologous recombination GO:0010569 11 0.239
nucleoside monophosphate catabolic process GO:0009125 159 0.232
ribonucleoside monophosphate metabolic process GO:0009161 187 0.216
sex determination GO:0007530 3 0.213
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.211
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.207
purine ribonucleoside metabolic process GO:0046128 437 0.187
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.186
ribonucleotide catabolic process GO:0009261 405 0.181
nucleoside triphosphate metabolic process GO:0009141 422 0.175
purine nucleotide catabolic process GO:0006195 405 0.174
dna catabolic process exonucleolytic GO:0000738 17 0.168
cellular macromolecular complex assembly GO:0034622 324 0.167
ribonucleoside catabolic process GO:0042454 406 0.167
purine nucleoside monophosphate catabolic process GO:0009128 158 0.162
negative regulation of thymocyte apoptotic process GO:0070244 1 0.161
purine ribonucleoside catabolic process GO:0046130 398 0.157
atp catabolic process GO:0006200 157 0.154
cell development GO:0048468 328 0.154
purine ribonucleotide catabolic process GO:0009154 404 0.152
somatic diversification of immunoglobulins GO:0016445 6 0.150
cell activation GO:0001775 213 0.143
positive regulation of cell proliferation GO:0008284 301 0.142
cellular macromolecule catabolic process GO:0044265 380 0.140
regulation of cell cycle GO:0051726 393 0.130
female gamete generation GO:0007292 2 0.130
mitotic recombination GO:0006312 8 0.130
nucleotide catabolic process GO:0009166 408 0.128
dna damage checkpoint GO:0000077 68 0.127
multicellular organismal aging GO:0010259 3 0.120
b cell activation GO:0042113 33 0.118
hemopoiesis GO:0030097 180 0.113
cell division GO:0051301 168 0.108
double strand break repair via nonhomologous end joining GO:0006303 10 0.108
meiotic nuclear division GO:0007126 10 0.107
Worm
rna catabolic process GO:0006401 71 0.104
leukocyte activation GO:0045321 164 0.102
rna processing GO:0006396 255 0.101
lymphocyte activation GO:0046649 133 0.101
cellular response to ionizing radiation GO:0071479 32 0.098
mrna processing GO:0006397 133 0.095
reciprocal dna recombination GO:0035825 4 0.089
nucleoside monophosphate metabolic process GO:0009123 191 0.088
regulation of cell cycle phase transition GO:1901987 126 0.087
nucleoside phosphate catabolic process GO:1901292 412 0.087
metaphase plate congression GO:0051310 18 0.087
purine nucleoside catabolic process GO:0006152 398 0.086
glycosyl compound catabolic process GO:1901658 413 0.086
regulation of dna metabolic process GO:0051052 153 0.084
Worm
negative regulation of double strand break repair GO:2000780 7 0.082
purine nucleoside monophosphate metabolic process GO:0009126 186 0.080
microtubule based process GO:0007017 210 0.079
leukocyte differentiation GO:0002521 98 0.079
reciprocal meiotic recombination GO:0007131 4 0.076
cellular response to organonitrogen compound GO:0071417 124 0.076
purine nucleoside triphosphate catabolic process GO:0009146 392 0.075
purine nucleoside triphosphate metabolic process GO:0009144 412 0.074
negative regulation of apoptotic process GO:0043066 316 0.073
dna integrity checkpoint GO:0031570 71 0.073
mitotic cell cycle checkpoint GO:0007093 68 0.070
chromosome separation GO:0051304 23 0.067
atp metabolic process GO:0046034 176 0.065
production of molecular mediator of immune response GO:0002440 37 0.065
organophosphate catabolic process GO:0046434 430 0.064
post embryonic development GO:0009791 2 0.064
regulation of transferase activity GO:0051338 355 0.061
microtubule cytoskeleton organization GO:0000226 176 0.061
oogenesis GO:0048477 2 0.058
cell activation involved in immune response GO:0002263 30 0.058
mitotic cell cycle process GO:1903047 286 0.058
cell cycle phase transition GO:0044770 173 0.058
regulation of cellular protein catabolic process GO:1903362 96 0.056
negative regulation of protein processing GO:0010955 142 0.056
regulation of protein catabolic process GO:0042176 155 0.056
negative regulation of programmed cell death GO:0043069 321 0.056
regeneration GO:0031099 4 0.055
negative regulation of dna recombination GO:0045910 6 0.055
anatomical structure homeostasis GO:0060249 100 0.054
Worm
response to nitrogen compound GO:1901698 184 0.054
regulation of protein kinase activity GO:0045859 289 0.054
hematopoietic or lymphoid organ development GO:0048534 186 0.053
chemical homeostasis GO:0048878 306 0.053
response to organonitrogen compound GO:0010243 156 0.052
positive regulation of cell death GO:0010942 263 0.052
ribonucleoside triphosphate metabolic process GO:0009199 412 0.051
regulation of double strand break repair GO:2000779 22 0.051
biological adhesion GO:0022610 331 0.051
response to abiotic stimulus GO:0009628 336 0.050
response to organic cyclic compound GO:0014070 204 0.050
mitotic cell cycle phase transition GO:0044772 162 0.050
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.050
dna catabolic process GO:0006308 49 0.050
response to caffeine GO:0031000 3 0.050
replication fork processing GO:0031297 13 0.049
response to radiation GO:0009314 151 0.049
gene conversion GO:0035822 1 0.048
regulation of mitotic sister chromatid segregation GO:0033047 27 0.048
protein modification by small protein conjugation GO:0032446 342 0.048
cellular response to endogenous stimulus GO:0071495 336 0.047
response to inorganic substance GO:0010035 127 0.046
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.044
regulation of proteasomal protein catabolic process GO:0061136 87 0.044
regulation of protein maturation GO:1903317 150 0.044
response to light stimulus GO:0009416 87 0.043
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.043
immune effector process GO:0002252 159 0.043
mitotic cell cycle arrest GO:0071850 4 0.043
base excision repair GO:0006284 21 0.043
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.043
negative regulation of cell cycle phase transition GO:1901988 89 0.042
protein maturation GO:0051604 233 0.042
mitotic g2 dna damage checkpoint GO:0007095 7 0.042
negative regulation of cell cycle GO:0045786 193 0.041
negative regulation of chromosome segregation GO:0051985 18 0.041
embryo development GO:0009790 123 0.041
regulation of proteolysis GO:0030162 293 0.041
cellular ketone metabolic process GO:0042180 80 0.040
determination of adult lifespan GO:0008340 2 0.040
resolution of meiotic recombination intermediates GO:0000712 3 0.040
protein processing GO:0016485 226 0.039
reproduction GO:0000003 63 0.039
Worm
negative regulation of mitotic cell cycle GO:0045930 102 0.038
nucleotide excision repair GO:0006289 31 0.038
Worm
regulation of dna recombination GO:0000018 23 0.038
positive regulation of dna metabolic process GO:0051054 73 0.038
positive regulation of apoptotic process GO:0043065 246 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.037
nucleoside catabolic process GO:0009164 408 0.037
regulation of cell cycle process GO:0010564 266 0.036
apoptotic signaling pathway GO:0097190 268 0.036
dna geometric change GO:0032392 32 0.036
immune response GO:0006955 307 0.036
cellular response to radiation GO:0071478 65 0.035
negative regulation of protein maturation GO:1903318 142 0.034
meiotic chromosome segregation GO:0045132 4 0.034
Worm
cell adhesion GO:0007155 325 0.034
g2 m transition of mitotic cell cycle GO:0000086 41 0.033
cellular component morphogenesis GO:0032989 314 0.033
cell cycle checkpoint GO:0000075 117 0.032
embryo development ending in birth or egg hatching GO:0009792 34 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.031
regulation of kinase activity GO:0043549 314 0.030
negative regulation of protein metabolic process GO:0051248 391 0.029
cellular response to oxygen containing compound GO:1901701 276 0.029
response to alkaloid GO:0043279 20 0.029
cellular divalent inorganic cation homeostasis GO:0072503 128 0.029
modification dependent protein catabolic process GO:0019941 209 0.028
negative regulation of cell death GO:0060548 345 0.028
dna dependent dna replication GO:0006261 44 0.028
Worm
protein ubiquitination GO:0016567 314 0.028
negative regulation of cell division GO:0051782 31 0.028
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.028
immunoglobulin production GO:0002377 12 0.028
ubiquitin dependent protein catabolic process GO:0006511 206 0.028
regulation of cytokine production GO:0001817 232 0.028
actin filament based process GO:0030029 224 0.027
somatic diversification of immune receptors GO:0002200 8 0.027
cytokinesis GO:0000910 96 0.027
response to purine containing compound GO:0014074 40 0.027
proteasomal protein catabolic process GO:0010498 176 0.027
oocyte maturation GO:0001556 1 0.027
adaptive immune response GO:0002250 49 0.027
calcium ion homeostasis GO:0055074 122 0.027
peripheral nervous system development GO:0007422 2 0.026
oocyte development GO:0048599 1 0.026
response to oxygen containing compound GO:1901700 369 0.026
negative regulation of catalytic activity GO:0043086 335 0.025
cytokine production GO:0001816 247 0.025
response to ionizing radiation GO:0010212 65 0.025
protein catabolic process GO:0030163 325 0.025
response to dietary excess GO:0002021 2 0.024
cellular response to abiotic stimulus GO:0071214 117 0.024
multicellular organism reproduction GO:0032504 42 0.024
negative regulation of cell cycle process GO:0010948 121 0.024
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.024
regulation of cell division GO:0051302 116 0.024
intrinsic apoptotic signaling pathway GO:0097193 127 0.024
cellular response to purine containing compound GO:0071415 3 0.023
negative regulation of mitosis GO:0045839 24 0.023
lymphocyte activation involved in immune response GO:0002285 20 0.023
thymocyte apoptotic process GO:0070242 2 0.023
cellular amino acid metabolic process GO:0006520 116 0.023
lymphocyte proliferation GO:0046651 70 0.022
cell cycle arrest GO:0007050 71 0.022
cellular protein catabolic process GO:0044257 261 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.022
mononuclear cell proliferation GO:0032943 71 0.021
response to uv GO:0009411 73 0.021
dephosphorylation GO:0016311 209 0.021
negative regulation of protein catabolic process GO:0042177 59 0.021
interstrand cross link repair GO:0036297 3 0.021
cellular amine metabolic process GO:0044106 41 0.021
mitotic dna integrity checkpoint GO:0044774 30 0.021
histone modification GO:0016570 251 0.021
blastocyst development GO:0001824 3 0.020
b cell mediated immunity GO:0019724 10 0.020
negative regulation of proteolysis GO:0045861 132 0.020
protein dephosphorylation GO:0006470 81 0.020
leukocyte mediated immunity GO:0002443 59 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
response to metal ion GO:0010038 84 0.020
postreplication repair GO:0006301 12 0.020
positive regulation of programmed cell death GO:0043068 249 0.019
cofactor metabolic process GO:0051186 87 0.019
meiotic cell cycle process GO:1903046 8 0.019
Worm
chromatin mediated maintenance of transcription GO:0048096 2 0.019
negative regulation of developmental process GO:0051093 247 0.019
mitotic sister chromatid separation GO:0051306 18 0.019
regulation of dna replication GO:0006275 68 0.019
Worm
cell type specific apoptotic process GO:0097285 125 0.019
hindbrain development GO:0030902 3 0.019
positive regulation of kinase activity GO:0033674 204 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
dna catabolic process endonucleolytic GO:0000737 37 0.018
growth GO:0040007 202 0.018
cellular protein complex assembly GO:0043623 188 0.018
cell morphogenesis GO:0000902 296 0.018
regulation of lymphocyte proliferation GO:0050670 64 0.018
cellular response to nitrogen compound GO:1901699 144 0.018
telomere maintenance via recombination GO:0000722 4 0.017
negative regulation of dna metabolic process GO:0051053 57 0.017
synaptic transmission cholinergic GO:0007271 2 0.017
tissue regeneration GO:0042246 3 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
neural tube closure GO:0001843 3 0.017
mitotic cell cycle GO:0000278 326 0.017
protein oligomerization GO:0051259 173 0.017
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.017
positive regulation of gtpase activity GO:0043547 166 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
mrna metabolic process GO:0016071 175 0.016
negative regulation of transferase activity GO:0051348 124 0.016
maintenance of location GO:0051235 112 0.016
establishment of chromosome localization GO:0051303 20 0.016
muscle cell differentiation GO:0042692 63 0.016
cellular response to external stimulus GO:0071496 111 0.016
lipid metabolic process GO:0006629 381 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
response to wounding GO:0009611 168 0.015
mrna 3 end processing GO:0031124 24 0.015
centrosome organization GO:0051297 58 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
metal ion transport GO:0030001 272 0.015
negative regulation of protein modification process GO:0031400 200 0.015
response to hypoxia GO:0001666 96 0.015
protein homooligomerization GO:0051260 100 0.015
mitotic dna damage checkpoint GO:0044773 28 0.015
cation homeostasis GO:0055080 189 0.015
regulation of meiotic cell cycle GO:0051445 4 0.015
amine metabolic process GO:0009308 44 0.014
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.014
response to cytokine GO:0034097 232 0.014
cellular response to alkaloid GO:0071312 11 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
axoneme assembly GO:0035082 3 0.014
system process GO:0003008 349 0.014
peptidyl lysine modification GO:0018205 144 0.014
developmental process involved in reproduction GO:0003006 66 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
negative regulation of response to dna damage stimulus GO:2001021 33 0.014
chromatin modification GO:0016568 298 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.014
actin filament based movement GO:0030048 17 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
mitotic nuclear division GO:0007067 119 0.013
positive regulation of organelle organization GO:0010638 195 0.013
cell projection organization GO:0030030 252 0.013
regulation of leukocyte activation GO:0002694 115 0.013
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.013
generation of precursor metabolites and energy GO:0006091 68 0.013
chromatin organization GO:0006325 351 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
cellular response to organic cyclic compound GO:0071407 127 0.012
leukocyte activation involved in immune response GO:0002366 30 0.012
sexual reproduction GO:0019953 37 0.012
behavior GO:0007610 112 0.012
stem cell maintenance GO:0019827 19 0.012
response to drug GO:0042493 81 0.012
multi organism reproductive process GO:0044703 54 0.012
cytoplasmic transport GO:0016482 379 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
positive regulation of mitotic cell cycle GO:0045931 60 0.012
organelle assembly GO:0070925 176 0.012
cellular homeostasis GO:0019725 196 0.012
spermatid development GO:0007286 4 0.011
dna replication GO:0006260 116 0.011
Worm
regulation of endopeptidase activity GO:0052548 170 0.011
cellular cation homeostasis GO:0030003 163 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
positive regulation of mononuclear cell proliferation GO:0032946 47 0.011
positive regulation of meiotic cell cycle GO:0051446 2 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
regulation of nucleocytoplasmic transport GO:0046822 98 0.011
male gamete generation GO:0048232 22 0.011
regulation of sister chromatid segregation GO:0033045 27 0.011
response to hormone GO:0009725 175 0.011
secretion by cell GO:0032940 226 0.011
leukocyte proliferation GO:0070661 74 0.011
myosin filament organization GO:0031033 2 0.011
secretion GO:0046903 254 0.011
regulation of cell shape GO:0008360 48 0.011
positive regulation of response to dna damage stimulus GO:2001022 43 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
head development GO:0060322 108 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010
locomotory behavior GO:0007626 1 0.010
negative regulation of cellular protein catabolic process GO:1903363 38 0.010
oocyte differentiation GO:0009994 2 0.010
cellular component disassembly GO:0022411 92 0.010
organelle localization GO:0051640 84 0.010
vesicle mediated transport GO:0016192 371 0.010
positive regulation of leukocyte activation GO:0002696 80 0.010
mrna catabolic process GO:0006402 56 0.010
cell fate commitment GO:0045165 27 0.010
neuroblast division GO:0055057 1 0.010
response to transition metal nanoparticle GO:1990267 29 0.010
primary neural tube formation GO:0014020 3 0.010

BRIP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.181
disease of cellular proliferation DOID:14566 174 0.153
breast cancer DOID:1612 21 0.079
thoracic cancer DOID:5093 21 0.079
cancer DOID:162 167 0.079
organ system cancer DOID:0050686 164 0.079
endocrine gland cancer DOID:170 26 0.021
aplastic anemia DOID:12449 30 0.021
bone marrow disease DOID:4961 31 0.021
anemia DOID:2355 55 0.021
hematopoietic system disease DOID:74 100 0.021
pancreatic cancer DOID:1793 8 0.018
reproductive organ cancer DOID:193 23 0.016
physical disorder DOID:0080015 41 0.011
congenital nervous system abnormality DOID:2490 21 0.011
congenital hypoplastic anemia DOID:1342 26 0.006
fanconi s anemia DOID:13636 16 0.006