Homo sapiens

29 known processes

PDS5B

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

(Aliases: AS3,FLJ23236,APRIN,KIAA0979,CG008)

PDS5B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic chromosome segregation GO:0045132 4 0.905
reciprocal meiotic recombination GO:0007131 4 0.854
mitotic sister chromatid cohesion GO:0007064 12 0.802
sister chromatid cohesion GO:0007062 24 0.700
chromosome segregation GO:0007059 114 0.696
regulation of dna endoreduplication GO:0032875 5 0.670
negative regulation of dna replication GO:0008156 29 0.655
Human
sister chromatid segregation GO:0000819 54 0.619
negative regulation of dna endoreduplication GO:0032876 5 0.461
mitotic cell cycle GO:0000278 326 0.423
organelle assembly GO:0070925 176 0.420
regulation of protein localization GO:0032880 296 0.356
cell development GO:0048468 328 0.346
protein localization to chromatin GO:0071168 11 0.341
cohesin localization to chromatin GO:0071921 4 0.335
vesicle mediated transport GO:0016192 371 0.335
regulation of cell differentiation GO:0045595 393 0.294
double strand break repair GO:0006302 101 0.293
post embryonic development GO:0009791 2 0.276
spermatid development GO:0007286 4 0.267
oogenesis GO:0048477 2 0.241
negative regulation of dna metabolic process GO:0051053 57 0.239
Human
regulation of cell cycle process GO:0010564 266 0.227
regulation of cell cycle GO:0051726 393 0.226
regulation of dna replication GO:0006275 68 0.223
Human
reproductive process GO:0022414 106 0.222
regulation of cohesin localization to chromatin GO:0071922 4 0.221
regulation of dna dependent dna replication GO:0090329 19 0.217
regulation of sister chromatid cohesion GO:0007063 9 0.216
organelle fission GO:0048285 149 0.214
dna dependent dna replication GO:0006261 44 0.210
negative regulation of developmental process GO:0051093 247 0.208
dna packaging GO:0006323 77 0.207
oocyte differentiation GO:0009994 2 0.207
male meiosis GO:0007140 1 0.199
stem cell differentiation GO:0048863 93 0.198
negative regulation of dna dependent dna replication GO:2000104 9 0.195
meiosis i GO:0007127 4 0.189
single organism cellular localization GO:1902580 332 0.187
regulation of dna metabolic process GO:0051052 153 0.179
Human
nuclear division GO:0000280 128 0.178
female gamete generation GO:0007292 2 0.172
negative regulation of cell differentiation GO:0045596 171 0.170
negative regulation of multicellular organismal process GO:0051241 317 0.153
dna replication GO:0006260 116 0.153
Human
positive regulation of cellular component organization GO:0051130 376 0.141
regulation of chromosome organization GO:0033044 103 0.139
dna recombination GO:0006310 77 0.137
receptor mediated endocytosis GO:0006898 84 0.137
mitotic nuclear division GO:0007067 119 0.135
endocytosis GO:0006897 159 0.130
cytokinesis GO:0000910 96 0.129
mitotic sister chromatid segregation GO:0000070 53 0.127
sex differentiation GO:0007548 45 0.125
spermatid differentiation GO:0048515 4 0.121
microtubule cytoskeleton organization GO:0000226 176 0.116
stem cell development GO:0048864 69 0.115
meiotic cell cycle GO:0051321 13 0.113
recombinational repair GO:0000725 50 0.113
ubiquitin dependent protein catabolic process GO:0006511 206 0.111
protein localization to organelle GO:0033365 280 0.109
dna repair GO:0006281 198 0.101
gonad development GO:0008406 34 0.095
cytokinesis completion of separation GO:0007109 3 0.094
single organism reproductive process GO:0044702 98 0.092
oocyte development GO:0048599 1 0.086
negative regulation of cell cycle GO:0045786 193 0.085
developmental process involved in reproduction GO:0003006 66 0.083
regulation of cellular amino acid metabolic process GO:0006521 6 0.082
regulation of binding GO:0051098 111 0.080
reproductive structure development GO:0048608 55 0.080
positive regulation of apoptotic process GO:0043065 246 0.079
chromosome condensation GO:0030261 15 0.079
embryo development GO:0009790 123 0.078
microtubule based process GO:0007017 210 0.074
meiotic nuclear division GO:0007126 10 0.072
system process GO:0003008 349 0.070
mitotic cell cycle process GO:1903047 286 0.067
dna conformation change GO:0071103 113 0.066
generation of neurons GO:0048699 152 0.065
negative regulation of protein metabolic process GO:0051248 391 0.065
cellular ketone metabolic process GO:0042180 80 0.065
endothelial cell migration GO:0043542 86 0.064
cell division GO:0051301 168 0.062
regulation of anatomical structure morphogenesis GO:0022603 286 0.062
central nervous system development GO:0007417 123 0.061
positive regulation of immune system process GO:0002684 283 0.060
negative regulation of cell cycle process GO:0010948 121 0.059
organelle localization GO:0051640 84 0.059
cellular amino acid metabolic process GO:0006520 116 0.058
reproductive system development GO:0061458 56 0.057
peptidyl lysine modification GO:0018205 144 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
nervous system development GO:0007399 293 0.054
ameboidal type cell migration GO:0001667 135 0.054
regulation of cellular amine metabolic process GO:0033238 11 0.052
brain development GO:0007420 97 0.052
double strand break repair via homologous recombination GO:0000724 50 0.052
mrna metabolic process GO:0016071 175 0.051
protein modification by small protein conjugation GO:0032446 342 0.050
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.050
purine nucleoside triphosphate catabolic process GO:0009146 392 0.049
anatomical structure formation involved in morphogenesis GO:0048646 284 0.047
dephosphorylation GO:0016311 209 0.047
intracellular protein transport GO:0006886 270 0.046
g1 s transition of mitotic cell cycle GO:0000082 78 0.045
positive regulation of catabolic process GO:0009896 310 0.045
development of primary sexual characteristics GO:0045137 35 0.042
tube development GO:0035295 125 0.041
negative regulation of cellular component organization GO:0051129 235 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.041
centrosome organization GO:0051297 58 0.040
reciprocal dna recombination GO:0035825 4 0.040
reproduction GO:0000003 63 0.039
regulation of mitotic cell cycle GO:0007346 189 0.038
amine metabolic process GO:0009308 44 0.036
regulation of nucleocytoplasmic transport GO:0046822 98 0.036
chemotaxis GO:0006935 157 0.034
regulation of meiotic cell cycle GO:0051445 4 0.034
mrna processing GO:0006397 133 0.033
negative regulation of organelle organization GO:0010639 126 0.033
organ morphogenesis GO:0009887 147 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
protein localization to chromosome GO:0034502 30 0.032
cellular macromolecular complex assembly GO:0034622 324 0.032
neuromuscular junction development GO:0007528 3 0.031
neuroblast proliferation GO:0007405 4 0.031
response to abiotic stimulus GO:0009628 336 0.031
regulation of gene expression epigenetic GO:0040029 73 0.031
meiotic cell cycle process GO:1903046 8 0.030
regulation of chromatin modification GO:1903308 51 0.030
cytoplasmic transport GO:0016482 379 0.030
positive regulation of hydrolase activity GO:0051345 331 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
multicellular organismal reproductive process GO:0048609 40 0.029
protein targeting to nucleus GO:0044744 104 0.029
regulation of locomotion GO:0040012 329 0.029
cellular homeostasis GO:0019725 196 0.029
mitotic sister chromatid separation GO:0051306 18 0.029
cellular response to oxygen containing compound GO:1901701 276 0.029
cellular component morphogenesis GO:0032989 314 0.029
regulation of growth GO:0040008 165 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.028
negative regulation of protein processing GO:0010955 142 0.028
regulation of intracellular transport GO:0032386 195 0.027
skeletal system development GO:0001501 79 0.027
embryo development ending in birth or egg hatching GO:0009792 34 0.027
negative regulation of cell proliferation GO:0008285 228 0.027
multi organism reproductive process GO:0044703 54 0.026
neurological system process GO:0050877 163 0.026
ribonucleoprotein complex subunit organization GO:0071826 81 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
circulatory system development GO:0072359 262 0.026
regulation of protein processing GO:0070613 150 0.026
cell cycle g1 s phase transition GO:0044843 80 0.026
sensory perception of mechanical stimulus GO:0050954 37 0.025
regulation of protein transport GO:0051223 213 0.025
purine containing compound catabolic process GO:0072523 411 0.025
sensory perception of sound GO:0007605 37 0.025
positive regulation of programmed cell death GO:0043068 249 0.024
epithelium development GO:0060429 227 0.024
cell morphogenesis GO:0000902 296 0.024
cell projection organization GO:0030030 252 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.023
nucleoside catabolic process GO:0009164 408 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
protein targeting GO:0006605 187 0.023
hindbrain development GO:0030902 3 0.023
nucleotide catabolic process GO:0009166 408 0.023
apoptotic signaling pathway GO:0097190 268 0.023
negative regulation of chromosome organization GO:2001251 48 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.023
negative regulation of chromosome segregation GO:0051985 18 0.022
cellular amine metabolic process GO:0044106 41 0.022
nuclear transport GO:0051169 179 0.022
angiogenesis GO:0001525 147 0.022
blastocyst development GO:0001824 3 0.022
embryonic forelimb morphogenesis GO:0035115 4 0.022
regulation of cell migration GO:0030334 289 0.022
head development GO:0060322 108 0.021
rna interference GO:0016246 4 0.021
tissue migration GO:0090130 119 0.021
response to radiation GO:0009314 151 0.021
cell cycle dna replication GO:0044786 11 0.021
multicellular organism reproduction GO:0032504 42 0.021
cell part morphogenesis GO:0032990 137 0.020
regulation of neurogenesis GO:0050767 82 0.020
embryonic viscerocranium morphogenesis GO:0048703 1 0.020
positive regulation of mitotic cell cycle GO:0045931 60 0.020
ribonucleoprotein complex assembly GO:0022618 78 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
mating GO:0007618 1 0.019
response to light stimulus GO:0009416 87 0.019
regulation of cell motility GO:2000145 299 0.019
ribonucleoprotein complex biogenesis GO:0022613 116 0.019
segmentation GO:0035282 4 0.019
purine nucleotide catabolic process GO:0006195 405 0.019
spermatogenesis GO:0007283 22 0.019
epithelial cell differentiation GO:0030855 141 0.019
spindle organization GO:0007051 53 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
protein import into nucleus GO:0006606 104 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
negative regulation of cell death GO:0060548 345 0.018
response to uv GO:0009411 73 0.018
locomotory behavior GO:0007626 1 0.018
stem cell maintenance GO:0019827 19 0.018
regulation of intracellular protein transport GO:0033157 123 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
biological adhesion GO:0022610 331 0.017
regulation of protein targeting GO:1903533 91 0.017
protein ubiquitination GO:0016567 314 0.017
determination of adult lifespan GO:0008340 2 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
behavior GO:0007610 112 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
protein oligomerization GO:0051259 173 0.017
cellular protein catabolic process GO:0044257 261 0.016
response to growth factor GO:0070848 205 0.016
epithelial cell migration GO:0010631 119 0.016
establishment of organelle localization GO:0051656 59 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
regulation of epithelial cell proliferation GO:0050678 113 0.016
retinal ganglion cell axon guidance GO:0031290 2 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
response to other organism GO:0051707 261 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
positive regulation of cell death GO:0010942 263 0.016
regulation of cellular component movement GO:0051270 334 0.016
rna splicing GO:0008380 131 0.016
positive regulation of transport GO:0051050 336 0.016
innate immune response GO:0045087 178 0.015
memory GO:0007613 3 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
mrna splicing via spliceosome GO:0000398 89 0.015
taxis GO:0042330 157 0.015
protein acetylation GO:0006473 116 0.015
neural tube patterning GO:0021532 2 0.015
histone modification GO:0016570 251 0.015
glycerolipid metabolic process GO:0046486 107 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
associative learning GO:0008306 1 0.015
modification dependent protein catabolic process GO:0019941 209 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
sexual reproduction GO:0019953 37 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
regulation of multicellular organism growth GO:0040014 8 0.014
tissue morphogenesis GO:0048729 96 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
organophosphate catabolic process GO:0046434 430 0.014
negative regulation of protein modification process GO:0031400 200 0.014
forelimb morphogenesis GO:0035136 4 0.014
response to gamma radiation GO:0010332 14 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
regulation of cell development GO:0060284 161 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
positive regulation of dna metabolic process GO:0051054 73 0.013
cellular response to nitrogen compound GO:1901699 144 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
neuron development GO:0048666 113 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
actin filament based process GO:0030029 224 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.013
protein maturation GO:0051604 233 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
sensory perception GO:0007600 103 0.013
cell adhesion GO:0007155 325 0.012
growth GO:0040007 202 0.012
regulation of chromosome segregation GO:0051983 44 0.012
circadian sleep wake cycle sleep GO:0050802 2 0.012
response to decreased oxygen levels GO:0036293 96 0.012
methylation GO:0032259 106 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
regulation of angiogenesis GO:0045765 92 0.012
positive regulation of cell division GO:0051781 59 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
positive regulation of proteolysis GO:0045862 142 0.012
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
atp metabolic process GO:0046034 176 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
actin cytoskeleton organization GO:0030036 207 0.012
neurogenesis GO:0022008 169 0.012
epithelial cell proliferation GO:0050673 128 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
negative regulation of growth GO:0045926 97 0.012
regulation of mitotic sister chromatid separation GO:0010965 27 0.012
protein catabolic process GO:0030163 325 0.012
pattern specification process GO:0007389 43 0.011
regulation of cellular response to stress GO:0080135 244 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
negative regulation of protein transport GO:0051224 75 0.011
multicellular organismal aging GO:0010259 3 0.011
tube morphogenesis GO:0035239 95 0.011
glial cell migration GO:0008347 4 0.011
cell activation GO:0001775 213 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
immune response GO:0006955 307 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
protein dephosphorylation GO:0006470 81 0.011
mitotic metaphase plate congression GO:0007080 14 0.011
regulation of cell division GO:0051302 116 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
cellular response to organonitrogen compound GO:0071417 124 0.010
cilium assembly GO:0042384 63 0.010
mapk cascade GO:0000165 288 0.010
extrinsic apoptotic signaling pathway GO:0097191 119 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
gtp metabolic process GO:0046039 239 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
regulation of meiosis GO:0040020 3 0.010
rostrocaudal neural tube patterning GO:0021903 1 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
positive regulation of cell proliferation GO:0008284 301 0.010

PDS5B disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.085
disease of cellular proliferation DOID:14566 174 0.085
organ system cancer DOID:0050686 164 0.085
endocrine gland cancer DOID:170 26 0.045
immune system disease DOID:2914 155 0.015
anemia DOID:2355 55 0.015
hematopoietic system disease DOID:74 100 0.015
breast cancer DOID:1612 21 0.015
thoracic cancer DOID:5093 21 0.015
central nervous system disease DOID:331 186 0.012
nervous system disease DOID:863 431 0.012