|
|
negative regulation of amyloid precursor protein catabolic process
|
GO:1902992 |
4 |
0.960
|
Human |
|
|
regulation of amyloid precursor protein catabolic process
|
GO:1902991 |
9 |
0.745
|
Human |
|
|
extracellular matrix disassembly
|
GO:0022617 |
16 |
0.683
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.605
|
|
|
|
amyloid precursor protein metabolic process
|
GO:0042982 |
17 |
0.595
|
Human |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.537
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.495
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.490
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.452
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.443
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.406
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.370
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.369
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.351
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.317
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.313
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.243
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.168
|
Mouse |
|
|
secretion
|
GO:0046903 |
254 |
0.148
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.140
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.117
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.108
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.103
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.094
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.094
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.092
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.087
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.087
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.081
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.080
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.077
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.076
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.074
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.074
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.073
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.072
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.071
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.070
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.069
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.068
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.067
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.065
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.063
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.062
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.060
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.060
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.058
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.058
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.057
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.056
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.056
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.056
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.054
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.054
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.053
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.051
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.051
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.050
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.050
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.049
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.049
|
Mouse |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.048
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.048
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.048
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.047
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.047
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.046
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.046
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.046
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.045
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.044
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.042
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.042
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.042
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.042
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.042
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.041
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.040
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.039
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.038
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.038
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.038
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.038
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.037
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.037
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.037
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.037
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.036
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.036
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.035
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.035
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.035
|
Mouse |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.035
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.034
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.033
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.033
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.033
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.032
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.032
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.032
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.032
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.032
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.031
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.031
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.031
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.031
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.031
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.031
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.030
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.030
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.030
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.030
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.030
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.030
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.030
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.029
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.029
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.029
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.029
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.029
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.029
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.029
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.029
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.029
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.028
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.028
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.028
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.028
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.028
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.027
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.027
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.026
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.026
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.026
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.026
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.026
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.025
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.025
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.025
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.025
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.025
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.025
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.025
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.025
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.025
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.024
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.024
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.024
|
Mouse |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.024
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.024
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.024
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.024
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.024
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.024
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.024
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.023
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.023
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.023
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.023
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.023
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.023
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.023
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.023
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.023
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.022
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.022
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.022
|
Mouse |
|
|
defense response
|
GO:0006952 |
315 |
0.022
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.022
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.022
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.022
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.022
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.022
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.022
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.022
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.022
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.021
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.021
|
Human |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.021
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.021
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.021
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.021
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.021
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.021
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.021
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.021
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.020
|
|
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.020
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.020
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.020
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.020
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.020
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.020
|
|
|
|
phospholipid transport
|
GO:0015914 |
23 |
0.020
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.020
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.020
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.020
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.020
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.020
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.019
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.019
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.019
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.019
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.019
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.019
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.019
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.019
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.019
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.019
|
|
|
|
memory
|
GO:0007613 |
3 |
0.019
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.019
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.019
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.018
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.018
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.018
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.018
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.018
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.018
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.018
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.018
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.018
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.018
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.018
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.018
|
|
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.018
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.017
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.017
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.017
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.017
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.017
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.017
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.017
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.017
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.017
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.017
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.017
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.017
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.017
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.017
|
|
|
|
lipid translocation
|
GO:0034204 |
2 |
0.017
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.017
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.017
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.017
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.017
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.016
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.016
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.016
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.016
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.016
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.016
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.016
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.016
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.016
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.016
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.016
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.016
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.016
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.016
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.016
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.016
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.016
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.016
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.016
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.016
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.016
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.016
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.016
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.016
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.015
|
|
|
|
phospholipid translocation
|
GO:0045332 |
2 |
0.015
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.015
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.015
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.015
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.015
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.015
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.015
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.015
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.015
|
|
|
|
organophosphate ester transport
|
GO:0015748 |
32 |
0.015
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.015
|
|
|
|
system process
|
GO:0003008 |
349 |
0.015
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.015
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.015
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.015
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.015
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.015
|
Mouse |
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.015
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.015
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.015
|
|
|
|
amino acid transport
|
GO:0006865 |
28 |
0.015
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.015
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.014
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.014
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.014
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.014
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.014
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.014
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.014
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.014
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.014
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.014
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.014
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.014
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.014
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.014
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.014
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.014
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.014
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.014
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.014
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.014
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.014
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.014
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.014
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.013
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.013
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.013
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.013
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.013
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.013
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.013
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.013
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.013
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.013
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.013
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.013
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.013
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.013
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.013
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.013
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.013
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
18 |
0.013
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.013
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.013
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.013
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.013
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.013
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.013
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.013
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.013
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.013
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.013
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.013
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.013
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.013
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.013
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.013
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.013
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.013
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.013
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.013
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.012
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.012
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.012
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.012
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.012
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.012
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.012
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.012
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.012
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.012
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.012
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.012
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.012
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.012
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.012
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.012
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.012
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.012
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.012
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.012
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.012
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.012
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.012
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.012
|
|
|
|
lipoprotein metabolic process
|
GO:0042157 |
42 |
0.012
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
38 |
0.012
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.012
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.012
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.012
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.012
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.012
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.012
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.012
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.012
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.012
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.012
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.012
|
Mouse |
|
|
spermatid development
|
GO:0007286 |
4 |
0.012
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.012
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.012
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.012
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.012
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.012
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.012
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.012
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.012
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.012
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.012
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.011
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.011
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.011
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.011
|
|
|
|
response to hyperoxia
|
GO:0055093 |
4 |
0.011
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.011
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.011
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.011
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.011
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.011
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.011
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.011
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.011
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.011
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.011
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.011
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.011
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.011
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.011
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.011
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.011
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.011
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.011
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.011
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.011
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.011
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.011
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.011
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.011
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.011
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.011
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.011
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.011
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.011
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.011
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.011
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.011
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.011
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.011
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.011
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.011
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.011
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.011
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.011
|
|
|
|
sterol homeostasis
|
GO:0055092 |
28 |
0.010
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.010
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.010
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.010
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.010
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.010
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.010
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.010
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.010
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.010
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.010
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.010
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.010
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.010
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.010
|
|
