|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.998
|
Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.894
|
Fly |
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.826
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.803
|
Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.801
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.634
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.552
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.524
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.512
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.509
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.498
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.486
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.457
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.398
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.368
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.347
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.301
|
|
|
|
memory
|
GO:0007613 |
3 |
0.295
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.293
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.281
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.262
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.245
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.238
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.233
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.219
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.216
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.215
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.209
|
Mouse |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.207
|
Mouse Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.190
|
Mouse |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.188
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.182
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.181
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.174
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.173
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.172
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.169
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.153
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.151
|
Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.147
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.139
|
Mouse |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.138
|
Mouse |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.120
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.117
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.110
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.109
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.108
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.108
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.100
|
Mouse Fly |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.098
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.096
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.094
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.092
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.092
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.090
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.090
|
Mouse |
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.090
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.088
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.086
|
Mouse Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.084
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.084
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.084
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.083
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.082
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.080
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.080
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.079
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.078
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.078
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.076
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.076
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.075
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.072
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.070
|
|
|
|
growth
|
GO:0040007 |
202 |
0.070
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.068
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.068
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.068
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.066
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.064
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.064
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.063
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.063
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.062
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.061
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.061
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.061
|
Mouse |
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.059
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.058
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.057
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.057
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.056
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.055
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.054
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.054
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.053
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.053
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.053
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.052
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.051
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.051
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.050
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.050
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.050
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.050
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.050
|
Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.050
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.048
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.048
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.047
|
Mouse |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.047
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.047
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.047
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.047
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.046
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.045
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.045
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.044
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.044
|
Mouse |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.044
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.044
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.043
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.043
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.043
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.042
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.042
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.042
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.042
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.041
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.041
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.040
|
Mouse |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.040
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.040
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.040
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.039
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.039
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.039
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.039
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.038
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.038
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.038
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.038
|
Mouse |
|
|
cell division
|
GO:0051301 |
168 |
0.038
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.038
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.038
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.037
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.037
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.037
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.037
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.037
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.037
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.037
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.037
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.036
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.036
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.036
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.036
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.035
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.035
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.035
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.035
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
233 |
0.035
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.034
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.034
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.034
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.034
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.033
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.033
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.033
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.033
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.033
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.032
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.032
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.032
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.031
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.031
|
Human |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.031
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.031
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.030
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.030
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.030
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.030
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.030
|
|
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
4 |
0.030
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.030
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.029
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.029
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.029
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.029
|
|
|
|
head development
|
GO:0060322 |
108 |
0.029
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.029
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.029
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.029
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.029
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.029
|
|
|
|
wnt signaling pathway calcium modulating pathway
|
GO:0007223 |
2 |
0.028
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.028
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.028
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.028
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.027
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.027
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.027
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.027
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.026
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.026
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.026
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.026
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.026
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.025
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.025
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.025
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.025
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.025
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.025
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.024
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.024
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.024
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.024
|
Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.024
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.024
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.024
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.023
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.023
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.023
|
Mouse |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.023
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.023
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.023
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.023
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.023
|
Human |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.022
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.022
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.022
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.022
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.022
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.022
|
Mouse |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.022
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.022
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.021
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.021
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.021
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.021
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.021
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.021
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.021
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.021
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.021
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.021
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.021
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.021
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.020
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.020
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.020
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.020
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.020
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.020
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.020
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.020
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.020
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.020
|
Mouse |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.020
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.020
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.019
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.019
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.019
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.019
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.019
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.019
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.019
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.019
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.019
|
Mouse |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.019
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.018
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.018
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.018
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.018
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.018
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.018
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.018
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.018
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.018
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.017
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.017
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.017
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.017
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.017
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.017
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.017
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.017
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.017
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.017
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.017
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.017
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.017
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.017
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.016
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.016
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.016
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.016
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.016
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.016
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.016
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.016
|
Fly |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.016
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.016
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.016
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.016
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.016
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.016
|
|
|
|
system process
|
GO:0003008 |
349 |
0.016
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.016
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.016
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.015
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.015
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.015
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.015
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.015
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.015
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.015
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.015
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.015
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.015
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.015
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.015
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.015
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.015
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.015
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.015
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.015
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.015
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.015
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.014
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.014
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.014
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.014
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.014
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.014
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.014
|
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.014
|
|
|
|
cellular response to misfolded protein
|
GO:0071218 |
2 |
0.014
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.014
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.014
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.014
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.014
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.014
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.014
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.013
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.013
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.013
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.013
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.013
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.013
|
Mouse |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.013
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.013
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.013
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.013
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.013
|
|
|
|
serine phosphorylation of stat protein
|
GO:0042501 |
4 |
0.013
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.013
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.013
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.013
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.013
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.013
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.013
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.013
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
4 |
0.013
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.013
|
Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.013
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.013
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.013
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.013
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.013
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.013
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.013
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.013
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.013
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.013
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.013
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.012
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.012
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.012
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.012
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.012
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.012
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.012
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.012
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.012
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.012
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.012
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.012
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.012
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.012
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.012
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.012
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.012
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.012
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.012
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.012
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.011
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.011
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.011
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.011
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.011
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.011
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.011
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.011
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.011
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.011
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.011
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.011
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.011
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.011
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.011
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.011
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.011
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.011
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.011
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.011
|
|
|
|
viral release from host cell
|
GO:0019076 |
21 |
0.011
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.011
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.011
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.011
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.011
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.010
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.010
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.010
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.010
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.010
|
Mouse |
|
|
secretion
|
GO:0046903 |
254 |
0.010
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.010
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.010
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.010
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.010
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.010
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.010
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.010
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.010
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.010
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.010
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.010
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.010
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.010
|
|
