Homo sapiens

0 known processes

SPIB

Spi-B transcription factor (Spi-1/PU.1 related)

(Aliases: SPI-B)

SPIB biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of thyroid hormone generation GO:2000609 2 0.535
immune system development GO:0002520 195 0.441
Human Mouse
regulation of cell differentiation GO:0045595 393 0.403
Human
lymphocyte activation GO:0046649 133 0.380
immune response GO:0006955 307 0.361
hematopoietic or lymphoid organ development GO:0048534 186 0.314
Human Mouse
chromatin organization GO:0006325 351 0.294
Human
cytokine production GO:0001816 247 0.274
regulation of cellular amine metabolic process GO:0033238 11 0.253
leukocyte activation GO:0045321 164 0.245
cell activation GO:0001775 213 0.222
positive regulation of cell proliferation GO:0008284 301 0.209
negative regulation of multicellular organismal process GO:0051241 317 0.182
response to lipid GO:0033993 206 0.180
regulation of cytokine production GO:0001817 232 0.175
positive regulation of developmental process GO:0051094 314 0.174
regulation of cellular amino acid metabolic process GO:0006521 6 0.174
positive regulation of immune system process GO:0002684 283 0.173
covalent chromatin modification GO:0016569 254 0.166
Human
leukocyte differentiation GO:0002521 98 0.163
Mouse
cell development GO:0048468 328 0.163
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.158
regulation of cellular ketone metabolic process GO:0010565 50 0.153
negative regulation of programmed cell death GO:0043069 321 0.151
hemopoiesis GO:0030097 180 0.139
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.137
chemical homeostasis GO:0048878 306 0.134
cellular ketone metabolic process GO:0042180 80 0.128
positive regulation of protein phosphorylation GO:0001934 313 0.124
regulation of mapk cascade GO:0043408 262 0.124
response to other organism GO:0051707 261 0.123
cellular response to cytokine stimulus GO:0071345 181 0.118
response to cytokine GO:0034097 232 0.117
positive regulation of cellular amine metabolic process GO:0033240 7 0.115
ras protein signal transduction GO:0007265 73 0.104
regulation of immune response GO:0050776 201 0.097
defense response GO:0006952 315 0.097
epithelium development GO:0060429 227 0.092
positive regulation of mapk cascade GO:0043410 190 0.092
sequestering of calcium ion GO:0051208 17 0.091
response to bacterium GO:0009617 144 0.090
positive regulation of transport GO:0051050 336 0.089
negative regulation of developmental process GO:0051093 247 0.088
secretion by cell GO:0032940 226 0.087
negative regulation of cell death GO:0060548 345 0.086
regulation of cell cycle GO:0051726 393 0.085
positive regulation of phosphorylation GO:0042327 394 0.085
interleukin 8 mediated signaling pathway GO:0038112 2 0.085
positive regulation of cell differentiation GO:0045597 211 0.079
secretion GO:0046903 254 0.078
cell projection organization GO:0030030 252 0.078
amine metabolic process GO:0009308 44 0.078
chromatin modification GO:0016568 298 0.077
Human
cellular response to oxygen containing compound GO:1901701 276 0.077
positive regulation of immune response GO:0050778 159 0.077
negative regulation of apoptotic process GO:0043066 316 0.076
response to abiotic stimulus GO:0009628 336 0.072
positive regulation of cytokine production GO:0001819 167 0.072
regulation of cell development GO:0060284 161 0.071
glycosyl compound catabolic process GO:1901658 413 0.070
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.069
positive regulation of apoptotic process GO:0043065 246 0.068
cellular amino acid metabolic process GO:0006520 116 0.068
regulation of leukocyte activation GO:0002694 115 0.067
regulation of protein transport GO:0051223 213 0.067
cellular component morphogenesis GO:0032989 314 0.065
lipid metabolic process GO:0006629 381 0.064
determination of adult lifespan GO:0008340 2 0.064
anatomical structure formation involved in morphogenesis GO:0048646 284 0.063
cellular amine metabolic process GO:0044106 41 0.063
regulation of response to external stimulus GO:0032101 222 0.063
regulation of ion transport GO:0043269 189 0.062
positive regulation of dermatome development GO:0061184 3 0.062
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.061
negative regulation of cell differentiation GO:0045596 171 0.061
histone modification GO:0016570 251 0.061
Human
post embryonic development GO:0009791 2 0.061
multicellular organismal aging GO:0010259 3 0.061
defense response to other organism GO:0098542 129 0.060
metal ion transport GO:0030001 272 0.060
female gamete generation GO:0007292 2 0.060
negative regulation of testosterone biosynthetic process GO:2000225 1 0.060
somatic stem cell maintenance GO:0035019 4 0.060
regulation of anatomical structure morphogenesis GO:0022603 286 0.059
cytoplasmic transport GO:0016482 379 0.059
oogenesis GO:0048477 2 0.059
single organism cellular localization GO:1902580 332 0.058
myeloid cell differentiation GO:0030099 117 0.058
Human Mouse
response to oxygen containing compound GO:1901700 369 0.057
peptidyl tyrosine modification GO:0018212 170 0.057
epithelial cell proliferation GO:0050673 128 0.057
response to external biotic stimulus GO:0043207 261 0.057
cellular response to lipid GO:0071396 127 0.056
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.056
positive regulation of cortisol biosynthetic process GO:2000066 1 0.056
response to biotic stimulus GO:0009607 276 0.056
regulation of myeloid cell differentiation GO:0045637 81 0.055
Human
ossification GO:0001503 121 0.054
nervous system development GO:0007399 293 0.054
neurogenesis GO:0022008 169 0.053
small gtpase mediated signal transduction GO:0007264 78 0.053
tube development GO:0035295 125 0.053
generation of neurons GO:0048699 152 0.052
cellular ion homeostasis GO:0006873 168 0.052
blood vessel development GO:0001568 172 0.052
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.052
lymphocyte differentiation GO:0030098 35 0.051
regulation of locomotion GO:0040012 329 0.051
regulation of protein kinase activity GO:0045859 289 0.051
metal ion homeostasis GO:0055065 169 0.050
positive regulation of cytoplasmic transport GO:1903651 82 0.050
nucleoside phosphate catabolic process GO:1901292 412 0.050
regulation of nucleotide metabolic process GO:0006140 269 0.050
regulation of lymphocyte activation GO:0051249 103 0.050
cell cell signaling GO:0007267 155 0.049
neuron projection development GO:0031175 106 0.049
positive regulation of cellular component organization GO:0051130 376 0.049
regulation of secretion GO:0051046 194 0.049
neuron differentiation GO:0030182 138 0.049
regulation of cytoplasmic transport GO:1903649 149 0.049
cellular homeostasis GO:0019725 196 0.048
regulation of homeostatic process GO:0032844 121 0.048
Human
positive regulation of cell death GO:0010942 263 0.048
activation of immune response GO:0002253 114 0.047
adaptive immune response GO:0002250 49 0.047
immune response activating signal transduction GO:0002757 90 0.047
negative regulation of male gonad development GO:2000019 1 0.046
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.046
regulation of peptidase activity GO:0052547 180 0.046
antigen receptor mediated signaling pathway GO:0050851 38 0.046
regulation of epithelial cell proliferation GO:0050678 113 0.044
regulation of leukocyte differentiation GO:1902105 61 0.044
positive regulation of glucocorticoid biosynthetic process GO:0031948 1 0.044
regulation of calcium ion transport into cytosol GO:0010522 33 0.044
regulation of transferase activity GO:0051338 355 0.044
cellular response to endogenous stimulus GO:0071495 336 0.043
regulation of cell cycle process GO:0010564 266 0.043
regulation of cellular response to stress GO:0080135 244 0.043
regulation of cellular component movement GO:0051270 334 0.043
myeloid leukocyte differentiation GO:0002573 60 0.043
Mouse
immune response regulating signaling pathway GO:0002764 97 0.042
positive regulation of programmed cell death GO:0043068 249 0.042
negative regulation of protein metabolic process GO:0051248 391 0.042
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.042
nucleotide catabolic process GO:0009166 408 0.042
positive regulation of stress activated mapk cascade GO:0032874 60 0.041
regulation of secretion by cell GO:1903530 177 0.041
cell morphogenesis involved in differentiation GO:0000904 144 0.041
cellular lipid metabolic process GO:0044255 303 0.041
calcium ion homeostasis GO:0055074 122 0.040
cation homeostasis GO:0055080 189 0.040
regulation of cell activation GO:0050865 125 0.040
regulation of kinase activity GO:0043549 314 0.040
immune effector process GO:0002252 159 0.040
protein processing GO:0016485 226 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
epithelial cell differentiation GO:0030855 141 0.039
positive regulation of intracellular transport GO:0032388 104 0.039
cell morphogenesis GO:0000902 296 0.039
negative regulation of testicular blood vessel morphogenesis GO:0061369 1 0.039
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.038
cellular response to abiotic stimulus GO:0071214 117 0.037
peptidyl lysine acetylation GO:0018394 101 0.037
Human
regulation of proteolysis GO:0030162 293 0.037
signal transduction by phosphorylation GO:0023014 297 0.037
positive regulation of catabolic process GO:0009896 310 0.037
gtp metabolic process GO:0046039 239 0.036
mapk cascade GO:0000165 288 0.036
positive regulation of hydrolase activity GO:0051345 331 0.036
regulation of t cell activation GO:0050863 77 0.036
cytokine mediated signaling pathway GO:0019221 109 0.036
cannabinoid signaling pathway GO:0038171 2 0.036
cellular response to dna damage stimulus GO:0006974 379 0.036
intracellular protein transport GO:0006886 270 0.036
positive regulation of transferase activity GO:0051347 227 0.036
cellular chemical homeostasis GO:0055082 180 0.036
positive regulation of aldosterone metabolic process GO:0032346 2 0.036
negative regulation of cellular component organization GO:0051129 235 0.035
Human
purine ribonucleotide catabolic process GO:0009154 404 0.035
regulation of ion homeostasis GO:2000021 73 0.035
nucleoside triphosphate metabolic process GO:0009141 422 0.035
cell fate determination GO:0001709 3 0.035
positive regulation of homeostatic process GO:0032846 47 0.035
regulation of establishment of protein localization GO:0070201 242 0.035
regulation of mononuclear cell proliferation GO:0032944 65 0.035
positive regulation of cellular component movement GO:0051272 181 0.034
negative regulation of androgen biosynthetic process GO:2000180 1 0.034
actin filament based process GO:0030029 224 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.034
apoptotic signaling pathway GO:0097190 268 0.034
segmentation GO:0035282 4 0.034
positive regulation of locomotion GO:0040017 186 0.034
bone mineralization GO:0030282 34 0.034
regulation of intracellular transport GO:0032386 195 0.033
cellular cation homeostasis GO:0030003 163 0.033
mitotic cell cycle GO:0000278 326 0.033
divalent metal ion transport GO:0070838 152 0.033
positive regulation of cellular catabolic process GO:0031331 284 0.033
divalent inorganic cation homeostasis GO:0072507 136 0.033
regulation of chromatin organization GO:1902275 56 0.032
Human
neuromuscular junction development GO:0007528 3 0.032
organophosphate catabolic process GO:0046434 430 0.032
regulation of jnk cascade GO:0046328 73 0.032
response to virus GO:0009615 126 0.032
circulatory system development GO:0072359 262 0.032
regulation of bone mineralization GO:0030500 29 0.032
regulation of cell migration GO:0030334 289 0.032
positive regulation of kinase activity GO:0033674 204 0.031
chemokine c c motif ligand 11 production GO:0071954 1 0.031
regulation of dermatome development GO:0061183 3 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.031
regulation of protein secretion GO:0050708 86 0.031
regulation of anatomical structure size GO:0090066 101 0.031
regulation of cellular component biogenesis GO:0044087 281 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
cardiovascular system development GO:0072358 262 0.030
protein acylation GO:0043543 138 0.030
Human
outflow tract septum morphogenesis GO:0003148 4 0.030
stem cell differentiation GO:0048863 93 0.030
blastoderm segmentation GO:0007350 2 0.030
cellular divalent inorganic cation homeostasis GO:0072503 128 0.030
head development GO:0060322 108 0.030
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
cloacal septation GO:0060197 1 0.030
organ formation GO:0048645 3 0.030
angiogenesis GO:0001525 147 0.030
endodermal cell fate specification GO:0001714 4 0.030
jnk cascade GO:0007254 80 0.030
regulation of cell projection organization GO:0031344 107 0.030
developmental programmed cell death GO:0010623 3 0.030
regulation of ras protein signal transduction GO:0046578 155 0.030
epidermis morphogenesis GO:0048730 3 0.030
maintenance of location GO:0051235 112 0.030
regulation of ras gtpase activity GO:0032318 128 0.030
nucleoside triphosphate catabolic process GO:0009143 394 0.030
negative regulation of immune system process GO:0002683 136 0.029
hair follicle morphogenesis GO:0031069 2 0.029
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.029
endodermal cell fate commitment GO:0001711 4 0.029
regulation of gtpase activity GO:0043087 180 0.029
regulation of gtp catabolic process GO:0033124 180 0.029
mitotic cell cycle process GO:1903047 286 0.029
positive regulation of leukocyte activation GO:0002696 80 0.029
cell projection morphogenesis GO:0048858 129 0.028
cellular metal ion homeostasis GO:0006875 146 0.028
embryonic forelimb morphogenesis GO:0035115 4 0.028
ion homeostasis GO:0050801 230 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
regulation of protein localization GO:0032880 296 0.028
histone acetylation GO:0016573 93 0.027
Human
regulation of metal ion transport GO:0010959 120 0.027
negative regulation of protein maturation GO:1903318 142 0.027
regulation of actin filament based process GO:0032970 141 0.027
negative regulation of homeostatic process GO:0032845 59 0.027
stress activated mapk cascade GO:0051403 93 0.027
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.027
negative regulation of protein modification process GO:0031400 200 0.027
Human
positive regulation of ion transport GO:0043270 87 0.027
positive regulation of calcium ion transport GO:0051928 51 0.027
neuron development GO:0048666 113 0.026
sex determination GO:0007530 3 0.026
cyclic nucleotide metabolic process GO:0009187 82 0.026
guanosine containing compound catabolic process GO:1901069 239 0.026
negative regulation of cell development GO:0010721 48 0.026
epithelium migration GO:0090132 119 0.026
internal peptidyl lysine acetylation GO:0018393 97 0.026
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.026
regulation of mitotic cell cycle GO:0007346 189 0.026
oocyte differentiation GO:0009994 2 0.026
b cell activation GO:0042113 33 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.026
positive regulation of proteolysis GO:0045862 142 0.026
positive regulation of cell motility GO:2000147 177 0.026
astrocyte chemotaxis GO:0035700 1 0.026
gtp catabolic process GO:0006184 237 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
purine containing compound catabolic process GO:0072523 411 0.026
positive regulation of protein transport GO:0051222 135 0.026
erythrocyte development GO:0048821 3 0.026
positive regulation of secretion by cell GO:1903532 108 0.025
internal protein amino acid acetylation GO:0006475 101 0.025
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
positive regulation of glucocorticoid metabolic process GO:0031945 1 0.025
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.025
aortic valve development GO:0003176 3 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
anterior posterior axis specification embryo GO:0008595 2 0.025
positive regulation of cell development GO:0010720 92 0.025
regulation of methylation dependent chromatin silencing GO:0090308 3 0.025
myeloid leukocyte activation GO:0002274 34 0.025
negative regulation of cell cycle GO:0045786 193 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
Human
biomineral tissue development GO:0031214 39 0.025
regulation of cellular component size GO:0032535 82 0.025
testosterone biosynthetic process GO:0061370 2 0.025
cellular defense response GO:0006968 2 0.025
negative regulation of endopeptidase activity GO:0010951 84 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.025
system process GO:0003008 349 0.024
negative regulation of locomotion GO:0040013 118 0.024
regulation of multi organism process GO:0043900 157 0.024
regulation of protein maturation GO:1903317 150 0.024
tube morphogenesis GO:0035239 95 0.024
growth GO:0040007 202 0.024
positive regulation of gtpase activity GO:0043547 166 0.024
regulation of male gonad development GO:2000018 4 0.024
positive regulation of hormone biosynthetic process GO:0046886 4 0.024
positive regulation of cell cycle GO:0045787 140 0.024
cell part morphogenesis GO:0032990 137 0.024
anterior posterior axis specification GO:0009948 2 0.024
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.024
innate immune response GO:0045087 178 0.024
positive regulation of nucleoside metabolic process GO:0045979 186 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
neuron fate commitment GO:0048663 2 0.024
blood vessel morphogenesis GO:0048514 162 0.024
negative regulation of epithelial cell proliferation GO:0050680 48 0.024
tripartite regional subdivision GO:0007351 2 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
regulation of hormone levels GO:0010817 125 0.024
forelimb morphogenesis GO:0035136 4 0.023
glycoprotein metabolic process GO:0009100 110 0.023
macromolecule methylation GO:0043414 97 0.023
Human
regulation of cell morphogenesis GO:0022604 153 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.023
regulation of testosterone biosynthetic process GO:2000224 2 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
stress activated protein kinase signaling cascade GO:0031098 94 0.023
vesicle mediated transport GO:0016192 371 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
hindbrain development GO:0030902 3 0.023
associative learning GO:0008306 1 0.023
cellular response to molecule of bacterial origin GO:0071219 62 0.023
response to decreased oxygen levels GO:0036293 96 0.023
regulation of growth GO:0040008 165 0.023
rho protein signal transduction GO:0007266 26 0.023
cell adhesion GO:0007155 325 0.023
response to lipopolysaccharide GO:0032496 70 0.023
positive regulation of cell cycle process GO:0090068 106 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
regulation of endopeptidase activity GO:0052548 170 0.023
regulation of protein processing GO:0070613 150 0.023
t cell activation GO:0042110 99 0.023
response to wounding GO:0009611 168 0.023
interleukin 13 secretion GO:0072611 2 0.023
protein maturation GO:0051604 233 0.023
skin development GO:0043588 76 0.023
positive regulation of protein kinase activity GO:0045860 190 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.022
regulation of vasculature development GO:1901342 97 0.022
positive regulation of secretion GO:0051047 116 0.022
wnt signaling pathway involved in wound healing spreading of epidermal cells GO:0035659 1 0.022
vasculature development GO:0001944 181 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
negative regulation of cell motility GO:2000146 104 0.022
protein localization to organelle GO:0033365 280 0.022
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.022
response to molecule of bacterial origin GO:0002237 82 0.022
positive regulation of cell migration GO:0030335 172 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
mononuclear cell proliferation GO:0032943 71 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
lymphocyte proliferation GO:0046651 70 0.022
heart morphogenesis GO:0003007 48 0.021
establishment of protein localization to organelle GO:0072594 172 0.021
cell growth GO:0016049 160 0.021
t cell differentiation in thymus GO:0033077 4 0.021
nucleoside catabolic process GO:0009164 408 0.021
eosinophil differentiation GO:0030222 2 0.021
neuroendocrine cell differentiation GO:0061101 2 0.021
paramesonephric duct development GO:0061205 2 0.021
regulation of ossification GO:0030278 58 0.021
regulation of stress activated mapk cascade GO:0032872 84 0.021
positive regulation of endothelial cell development GO:1901552 1 0.021
regulation of protein complex assembly GO:0043254 147 0.021
biological adhesion GO:0022610 331 0.021
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.021
stem cell development GO:0048864 69 0.021
regulation of epithelial cell migration GO:0010632 93 0.021
organ morphogenesis GO:0009887 147 0.021
regulation of neural precursor cell proliferation GO:2000177 4 0.021
single organism membrane organization GO:0044802 268 0.021
cellular macromolecular complex assembly GO:0034622 324 0.020
cell division GO:0051301 168 0.020
regulation of intracellular protein transport GO:0033157 123 0.020
cellular response to hormone stimulus GO:0032870 125 0.020
positive regulation of interleukin 13 production GO:0032736 4 0.020
jak stat cascade GO:0007259 46 0.020
regulation of response to wounding GO:1903034 101 0.020
muscle structure development GO:0061061 98 0.020
negative regulation of protein processing GO:0010955 142 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.020
epidermis development GO:0008544 59 0.020
memory GO:0007613 3 0.020
g protein coupled receptor signaling pathway GO:0007186 207 0.020
negative regulation of ossification GO:0030279 21 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
positive regulation of t cell activation GO:0050870 54 0.020
cellular calcium ion homeostasis GO:0006874 117 0.020
microtubule based process GO:0007017 210 0.019
regeneration GO:0031099 4 0.019
positive regulation of cell division GO:0051781 59 0.019
calcium ion transport GO:0006816 147 0.019
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.019
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.019
positive regulation of cell activation GO:0050867 81 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
digestive tract development GO:0048565 75 0.019
negative regulation of establishment of endothelial barrier GO:1903141 1 0.019
regulation of biomineral tissue development GO:0070167 31 0.019
single organismal cell cell adhesion GO:0016337 148 0.019
response to growth factor GO:0070848 205 0.019
androgen biosynthetic process GO:0006702 3 0.019
cation transport GO:0006812 331 0.019
salivary gland morphogenesis GO:0007435 4 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
positive regulation of organelle organization GO:0010638 195 0.018
cellular response to biotic stimulus GO:0071216 71 0.018
cartilage condensation GO:0001502 1 0.018
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.018
membrane organization GO:0061024 292 0.018
motor neuron axon guidance GO:0008045 2 0.018
actin cytoskeleton organization GO:0030036 207 0.018
positive regulation of ras gtpase activity GO:0032320 117 0.018
cardiac right ventricle morphogenesis GO:0003215 3 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
lipid biosynthetic process GO:0008610 177 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.018
regulation of cell motility GO:2000145 299 0.018
regulation of camp metabolic process GO:0030814 52 0.018
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.018
regulation of interleukin 13 secretion GO:2000665 2 0.018
limb bud formation GO:0060174 1 0.018
positive regulation of interleukin 5 production GO:0032754 3 0.018
regulation of protein targeting GO:1903533 91 0.018
negative regulation of growth GO:0045926 97 0.018
neurological system process GO:0050877 163 0.018
regulation of calcium ion transport GO:0051924 79 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
response to alcohol GO:0097305 64 0.018
hindlimb morphogenesis GO:0035137 2 0.018
locomotory behavior GO:0007626 1 0.018
osteoblast differentiation GO:0001649 92 0.018
positive regulation of odontogenesis GO:0042482 3 0.018
neuron projection morphogenesis GO:0048812 50 0.018
peptidyl lysine modification GO:0018205 144 0.018
Human
protein localization to nucleus GO:0034504 136 0.018
response to tumor necrosis factor GO:0034612 76 0.018
sequestering of metal ion GO:0051238 24 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
regulation of neurogenesis GO:0050767 82 0.017
sphingosine 1 phosphate signaling pathway GO:0003376 1 0.017
metencephalon development GO:0022037 2 0.017
monocarboxylic acid metabolic process GO:0032787 185 0.017
myeloid dendritic cell chemotaxis GO:0002408 3 0.017
regulation of chromatin modification GO:1903308 51 0.017
Human
actin filament organization GO:0007015 128 0.017
antigen processing and presentation of lipid antigen via mhc class ib GO:0048003 1 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.017
negative regulation of peptidase activity GO:0010466 91 0.017
heart formation GO:0060914 2 0.017
peptide secretion GO:0002790 51 0.017
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.017
regulation of defense response GO:0031347 154 0.017
oxidation reduction process GO:0055114 396 0.017
negative regulation of organelle organization GO:0010639 126 0.017
Human
apoptotic process involved in morphogenesis GO:0060561 3 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
cellular response to organic cyclic compound GO:0071407 127 0.017
regulation of canonical wnt signaling pathway GO:0060828 88 0.017
reactive nitrogen species metabolic process GO:2001057 3 0.017
protein ubiquitination GO:0016567 314 0.017

SPIB disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.510
hematopoietic system disease DOID:74 100 0.232
primary immunodeficiency disease DOID:612 36 0.073
blood protein disease DOID:620 16 0.063
b cell deficiency DOID:2115 17 0.050
agammaglobulinemia DOID:2583 16 0.042
musculoskeletal system disease DOID:17 223 0.037
common variable immunodeficiency DOID:12177 10 0.034
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
connective tissue disease DOID:65 109 0.021
central nervous system disease DOID:331 186 0.019
nervous system disease DOID:863 431 0.019
organ system cancer DOID:0050686 164 0.018