Homo sapiens

0 known processes

SIM2

single-minded homolog 2 (Drosophila)

(Aliases: MGC119447,bHLHe15,SIM)

SIM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron fate commitment GO:0048663 2 0.596
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.473
Mouse
organ morphogenesis GO:0009887 147 0.441
organ formation GO:0048645 3 0.405
extraocular skeletal muscle development GO:0002074 1 0.387
circulatory system development GO:0072359 262 0.364
epithelium development GO:0060429 227 0.347
endocrine system development GO:0035270 26 0.342
negative regulation of developmental process GO:0051093 247 0.340
regulation of cell differentiation GO:0045595 393 0.333
specification of organ identity GO:0010092 3 0.323
anatomical structure formation involved in morphogenesis GO:0048646 284 0.308
regulation of stem cell differentiation GO:2000736 56 0.301
cardiovascular system development GO:0072358 262 0.296
negative regulation of multicellular organismal process GO:0051241 317 0.291
regulation of hormone levels GO:0010817 125 0.270
Human
positive regulation of developmental process GO:0051094 314 0.263
cellular ketone metabolic process GO:0042180 80 0.253
regulation of cellular ketone metabolic process GO:0010565 50 0.248
system process GO:0003008 349 0.230
negative regulation of cell differentiation GO:0045596 171 0.210
cellular amine metabolic process GO:0044106 41 0.205
nerve development GO:0021675 4 0.205
embryonic morphogenesis GO:0048598 85 0.199
regulation of anatomical structure morphogenesis GO:0022603 286 0.199
nervous system development GO:0007399 293 0.197
Fly
epithelial cell differentiation GO:0030855 141 0.195
tissue morphogenesis GO:0048729 96 0.193
cell development GO:0048468 328 0.192
Fly
stem cell differentiation GO:0048863 93 0.188
amine metabolic process GO:0009308 44 0.187
vasculature development GO:0001944 181 0.185
nephron tubule formation GO:0072079 1 0.184
cellular amino acid metabolic process GO:0006520 116 0.182
skeletal system development GO:0001501 79 0.177
regulation of cellular amine metabolic process GO:0033238 11 0.174
inner ear morphogenesis GO:0042472 4 0.172
cell cell signaling GO:0007267 155 0.168
positive regulation of cellular amine metabolic process GO:0033240 7 0.166
secretion GO:0046903 254 0.166
muscle structure development GO:0061061 98 0.163
tube development GO:0035295 125 0.162
Mouse
regulation of cell motility GO:2000145 299 0.152
response to oxygen containing compound GO:1901700 369 0.150
regulation of thyroid hormone generation GO:2000609 2 0.149
negative regulation of cell death GO:0060548 345 0.144
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.133
hindbrain development GO:0030902 3 0.133
positive regulation of cell proliferation GO:0008284 301 0.132
regulation of cellular amino acid metabolic process GO:0006521 6 0.130
mesonephric duct development GO:0072177 3 0.130
negative regulation of apoptotic process GO:0043066 316 0.127
Human
segmentation GO:0035282 4 0.125
negative regulation of kidney development GO:0090185 2 0.123
regulation of locomotion GO:0040012 329 0.121
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.121
cranial nerve development GO:0021545 4 0.119
forelimb morphogenesis GO:0035136 4 0.119
cellular response to endogenous stimulus GO:0071495 336 0.119
digestive system development GO:0055123 75 0.117
gland development GO:0048732 48 0.115
negative regulation of programmed cell death GO:0043069 321 0.115
Human
urogenital system development GO:0001655 65 0.113
regulation of cellular component movement GO:0051270 334 0.113
regulation of cell development GO:0060284 161 0.108
secretion by cell GO:0032940 226 0.107
cellular response to oxygen containing compound GO:1901701 276 0.106
pattern specification involved in kidney development GO:0061004 1 0.106
hormone secretion GO:0046879 65 0.106
tube morphogenesis GO:0035239 95 0.106
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.105
embryonic forelimb morphogenesis GO:0035115 4 0.104
post embryonic development GO:0009791 2 0.104
generation of neurons GO:0048699 152 0.102
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.100
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.099
positive regulation of cell differentiation GO:0045597 211 0.099
regulation of cell migration GO:0030334 289 0.097
locomotory behavior GO:0007626 1 0.097
Fly
mesenchyme development GO:0060485 59 0.097
cell morphogenesis GO:0000902 296 0.095
Fly
positive regulation of cell death GO:0010942 263 0.095
cellular component morphogenesis GO:0032989 314 0.093
Fly
cell fate determination GO:0001709 3 0.092
mapk cascade GO:0000165 288 0.092
regionalization GO:0003002 29 0.091
pattern specification process GO:0007389 43 0.091
Mouse
digestive tract development GO:0048565 75 0.087
blood vessel development GO:0001568 172 0.087
neurogenesis GO:0022008 169 0.087
Fly
heart development GO:0007507 95 0.086
somatic stem cell maintenance GO:0035019 4 0.086
central nervous system development GO:0007417 123 0.085
Fly
chemical homeostasis GO:0048878 306 0.084
Human
response to abiotic stimulus GO:0009628 336 0.083
Human
morphogenesis of an epithelium GO:0002009 60 0.082
neuron differentiation GO:0030182 138 0.082
Fly
stem cell development GO:0048864 69 0.082
cardiac cell fate determination GO:0060913 3 0.081
follicle stimulating hormone secretion GO:0046884 3 0.080
head development GO:0060322 108 0.079
Fly
positive regulation of programmed cell death GO:0043068 249 0.079
positive regulation of apoptotic process GO:0043065 246 0.078
regulation of secretion GO:0051046 194 0.078
embryonic epithelial tube formation GO:0001838 4 0.078
cell differentiation in spinal cord GO:0021515 1 0.078
menstrual cycle phase GO:0022601 2 0.077
cell morphogenesis involved in differentiation GO:0000904 144 0.077
Fly
regulation of cell cycle GO:0051726 393 0.076
spinal cord development GO:0021510 4 0.075
muscle tissue development GO:0060537 62 0.074
mesonephric tubule formation GO:0072172 1 0.074
embryonic organ development GO:0048568 36 0.073
renal system development GO:0072001 63 0.073
epithelial tube morphogenesis GO:0060562 38 0.073
brain development GO:0007420 97 0.072
Fly
behavior GO:0007610 112 0.071
Fly
regulation of kinase activity GO:0043549 314 0.070
forebrain regionalization GO:0021871 3 0.070
epithelial cell proliferation GO:0050673 128 0.069
thymus development GO:0048538 3 0.069
negative regulation of locomotion GO:0040013 118 0.068
response to lipid GO:0033993 206 0.068
kidney development GO:0001822 53 0.068
endodermal cell fate commitment GO:0001711 4 0.067
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.067
peptide hormone secretion GO:0030072 50 0.066
negative regulation of cell proliferation GO:0008285 228 0.065
positive regulation of cellular component organization GO:0051130 376 0.065
cellular response to hormone stimulus GO:0032870 125 0.064
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.063
regulation of proteolysis GO:0030162 293 0.063
positive regulation of phosphorylation GO:0042327 394 0.062
hormone transport GO:0009914 68 0.062
immune system development GO:0002520 195 0.062
cell projection organization GO:0030030 252 0.062
Fly
mesodermal cell fate specification GO:0007501 2 0.061
amide transport GO:0042886 76 0.061
chordate embryonic development GO:0043009 34 0.061
embryonic organ morphogenesis GO:0048562 24 0.060
response to organic cyclic compound GO:0014070 204 0.059
positive regulation of protein phosphorylation GO:0001934 313 0.059
mitotic cell cycle GO:0000278 326 0.059
reproductive process GO:0022414 106 0.059
regulation of metanephros size GO:0035566 1 0.059
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.059
small gtpase mediated signal transduction GO:0007264 78 0.058
peptide secretion GO:0002790 51 0.058
embryo development GO:0009790 123 0.058
Mouse
growth GO:0040007 202 0.058
regulation of mapk cascade GO:0043408 262 0.057
regulation of transferase activity GO:0051338 355 0.057
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.057
endodermal cell fate specification GO:0001714 4 0.056
angiogenesis GO:0001525 147 0.056
male genitalia development GO:0030539 1 0.056
blood vessel morphogenesis GO:0048514 162 0.055
female gamete generation GO:0007292 2 0.055
cell adhesion GO:0007155 325 0.055
negative regulation of stem cell differentiation GO:2000737 22 0.054
blastoderm segmentation GO:0007350 2 0.054
g protein coupled receptor signaling pathway GO:0007186 207 0.054
regulation of hormone secretion GO:0046883 57 0.053
ras protein signal transduction GO:0007265 73 0.053
cellular response to dna damage stimulus GO:0006974 379 0.053
hormone metabolic process GO:0042445 61 0.053
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.052
heart morphogenesis GO:0003007 48 0.052
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.052
negative regulation of cell migration GO:0030336 102 0.052
response to hormone GO:0009725 175 0.051
skeletal system morphogenesis GO:0048705 24 0.051
signal transduction by phosphorylation GO:0023014 297 0.051
positive regulation of epithelial cell proliferation GO:0050679 65 0.051
embryonic camera type eye development GO:0031076 2 0.051
regulation of nucleotide metabolic process GO:0006140 269 0.051
mesenchymal cell development GO:0014031 50 0.051
regulation of male gonad development GO:2000018 4 0.050
negative regulation of cellular component movement GO:0051271 106 0.050
nitrogen compound transport GO:0071705 191 0.050
ureteric bud development GO:0001657 13 0.050
response to nitrogen compound GO:1901698 184 0.049
ion transmembrane transport GO:0034220 338 0.049
negative regulation of protein metabolic process GO:0051248 391 0.049
regulation of protein kinase activity GO:0045859 289 0.049
wnt signaling pathway GO:0016055 156 0.049
formation of primary germ layer GO:0001704 42 0.049
oogenesis GO:0048477 2 0.049
cation transmembrane transport GO:0098655 238 0.049
actin filament based process GO:0030029 224 0.048
immune response GO:0006955 307 0.048
muscle organ development GO:0007517 56 0.048
ameboidal type cell migration GO:0001667 135 0.048
multicellular organismal aging GO:0010259 3 0.047
positive regulation of transport GO:0051050 336 0.047
striated muscle tissue development GO:0014706 59 0.047
neural crest cell development GO:0014032 3 0.047
regulation of secretion by cell GO:1903530 177 0.047
nephron epithelium morphogenesis GO:0072088 15 0.047
positive regulation of transferase activity GO:0051347 227 0.047
regulation of peptidase activity GO:0052547 180 0.046
peripheral nervous system development GO:0007422 2 0.046
morphogenesis of a branching structure GO:0001763 21 0.046
regulation of protein localization GO:0032880 296 0.046
single organism reproductive process GO:0044702 98 0.046
positive regulation of hydrolase activity GO:0051345 331 0.046
nucleoside catabolic process GO:0009164 408 0.045
biological adhesion GO:0022610 331 0.045
transmembrane transport GO:0055085 399 0.045
positive regulation of mapk cascade GO:0043410 190 0.045
lipid metabolic process GO:0006629 381 0.045
regulation of cellular response to stress GO:0080135 244 0.044
Human
cell substrate adhesion GO:0031589 132 0.044
cell fate commitment GO:0045165 27 0.044
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.043
negative regulation of phosphate metabolic process GO:0045936 267 0.043
negative regulation of cell motility GO:2000146 104 0.043
positive regulation of protein kinase activity GO:0045860 190 0.043
regulation of cellular component biogenesis GO:0044087 281 0.043
taxis GO:0042330 157 0.043
Fly
positive regulation of immune system process GO:0002684 283 0.043
response to wounding GO:0009611 168 0.042
regulation of epithelial cell proliferation GO:0050678 113 0.042
nucleoside triphosphate metabolic process GO:0009141 422 0.042
purine ribonucleoside metabolic process GO:0046128 437 0.042
mesodermal cell fate commitment GO:0001710 2 0.042
ion homeostasis GO:0050801 230 0.042
anterior posterior axis specification GO:0009948 2 0.042
pancreas development GO:0031016 19 0.042
morphogenesis of a branching epithelium GO:0061138 20 0.042
developmental programmed cell death GO:0010623 3 0.042
ribonucleoside catabolic process GO:0042454 406 0.042
regulation of protein serine threonine kinase activity GO:0071900 179 0.042
cytoplasmic transport GO:0016482 379 0.042
peptide transport GO:0015833 74 0.042
positive regulation of cell development GO:0010720 92 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
regulation of organ morphogenesis GO:2000027 24 0.041
regulation of cytokine production GO:0001817 232 0.041
Human
regulation of cell cycle process GO:0010564 266 0.041
regulation of endopeptidase activity GO:0052548 170 0.041
regulation of mitotic cell cycle GO:0007346 189 0.041
negative regulation of cellular protein metabolic process GO:0032269 353 0.041
chemotaxis GO:0006935 157 0.041
Fly
cardiac muscle tissue development GO:0048738 39 0.041
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
negative regulation of cell development GO:0010721 48 0.041
neuron development GO:0048666 113 0.040
Fly
neurological system process GO:0050877 163 0.040
positive regulation of cardioblast differentiation GO:0051891 2 0.039
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.039
purine containing compound catabolic process GO:0072523 411 0.039
heart formation GO:0060914 2 0.039
negative regulation of transport GO:0051051 176 0.039
membrane organization GO:0061024 292 0.039
nucleoside phosphate catabolic process GO:1901292 412 0.038
organophosphate catabolic process GO:0046434 430 0.038
kidney morphogenesis GO:0060993 19 0.038
chromatin organization GO:0006325 351 0.038
regulation of mesonephros development GO:0061217 3 0.038
determination of adult lifespan GO:0008340 2 0.038
purine nucleotide catabolic process GO:0006195 405 0.037
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.037
metal ion homeostasis GO:0055065 169 0.037
epidermis morphogenesis GO:0048730 3 0.037
canonical wnt signaling pathway GO:0060070 116 0.037
mesenchymal cell differentiation GO:0048762 52 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.036
positive regulation of kinase activity GO:0033674 204 0.036
response to organonitrogen compound GO:0010243 156 0.036
purine nucleoside catabolic process GO:0006152 398 0.036
forebrain generation of neurons GO:0021872 3 0.036
negative regulation of catalytic activity GO:0043086 335 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
gastrulation GO:0007369 51 0.036
ribonucleoside triphosphate metabolic process GO:0009199 412 0.036
cellular chemical homeostasis GO:0055082 180 0.036
negative regulation of cell cycle GO:0045786 193 0.035
cation transport GO:0006812 331 0.035
organic hydroxy compound metabolic process GO:1901615 147 0.035
foramen ovale closure GO:0035922 1 0.035
epidermis development GO:0008544 59 0.035
protein localization to organelle GO:0033365 280 0.035
signal release GO:0023061 70 0.035
cellular homeostasis GO:0019725 196 0.035
cardiac right ventricle morphogenesis GO:0003215 3 0.035
response to cytokine GO:0034097 232 0.035
Human
connective tissue development GO:0061448 39 0.035
regulation of purine nucleotide metabolic process GO:1900542 264 0.034
wound healing GO:0042060 115 0.034
nephron morphogenesis GO:0072028 15 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.034
protein processing GO:0016485 226 0.034
negative regulation of cellular component organization GO:0051129 235 0.034
nucleotide catabolic process GO:0009166 408 0.034
cartilage condensation GO:0001502 1 0.034
nucleoside triphosphate catabolic process GO:0009143 394 0.034
nuclear transport GO:0051169 179 0.034
chromatin modification GO:0016568 298 0.033
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.033
regulation of cell adhesion GO:0030155 166 0.033
cell type specific apoptotic process GO:0097285 125 0.033
Human
epithelium migration GO:0090132 119 0.033
ectodermal placode development GO:0071696 1 0.033
neuromuscular junction development GO:0007528 3 0.033
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.033
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.032
sensory organ development GO:0007423 52 0.032
cell projection morphogenesis GO:0048858 129 0.032
Fly
positive regulation of cell cycle GO:0045787 140 0.032
tissue migration GO:0090130 119 0.032
cellular macromolecule catabolic process GO:0044265 380 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.032
cell part morphogenesis GO:0032990 137 0.032
Fly
single organism cellular localization GO:1902580 332 0.032
adult locomotory behavior GO:0008344 1 0.032
Fly
positive regulation of catabolic process GO:0009896 310 0.032
reactive oxygen species metabolic process GO:0072593 75 0.032
regulation of nervous system development GO:0051960 88 0.032
neuron projection development GO:0031175 106 0.032
Fly
photoreceptor cell differentiation GO:0046530 2 0.031
regulation of multi organism process GO:0043900 157 0.031
memory GO:0007613 3 0.031
rho protein signal transduction GO:0007266 26 0.031
nephric duct development GO:0072176 4 0.031
single organism membrane organization GO:0044802 268 0.031
soft palate development GO:0060023 3 0.031
apoptotic signaling pathway GO:0097190 268 0.030
Human
negative regulation of hydrolase activity GO:0051346 182 0.030
response to biotic stimulus GO:0009607 276 0.030
regulation of protein transport GO:0051223 213 0.030
positive regulation of dermatome development GO:0061184 3 0.030
regulation of cysteine type endopeptidase activity GO:2000116 127 0.030
positive regulation of locomotion GO:0040017 186 0.030
cranial nerve morphogenesis GO:0021602 1 0.030
protein catabolic process GO:0030163 325 0.030
positive regulation of cytokine production GO:0001819 167 0.030
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.029
limbic system development GO:0021761 3 0.029
paramesonephric duct development GO:0061205 2 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
hemopoiesis GO:0030097 180 0.029
regulation of response to external stimulus GO:0032101 222 0.029
intracellular protein transport GO:0006886 270 0.029
response to hypoxia GO:0001666 96 0.029
Human
defense response GO:0006952 315 0.029
ribonucleotide catabolic process GO:0009261 405 0.029
renal tubule development GO:0061326 19 0.029
metencephalon development GO:0022037 2 0.029
regulation of growth GO:0040008 165 0.029
ectodermal placode formation GO:0060788 1 0.029
epidermal cell differentiation GO:0009913 45 0.029
neural tube formation GO:0001841 3 0.029
regulation of angiogenesis GO:0045765 92 0.029
metal ion transport GO:0030001 272 0.029
protein maturation GO:0051604 233 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
embryonic camera type eye morphogenesis GO:0048596 2 0.028
peptidyl tyrosine modification GO:0018212 170 0.028
branching morphogenesis of an epithelial tube GO:0048754 19 0.028
positive regulation of cell migration GO:0030335 172 0.028
receptor metabolic process GO:0043112 81 0.028
Human
axis elongation GO:0003401 4 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.028
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.028
gtp metabolic process GO:0046039 239 0.028
cellular response to cytokine stimulus GO:0071345 181 0.028
Human
cell activation GO:0001775 213 0.028
bmp signaling pathway involved in heart development GO:0061312 3 0.028
regulation of vasculature development GO:1901342 97 0.028
pharynx development GO:0060465 1 0.028
epithelial cell migration GO:0010631 119 0.028
cation homeostasis GO:0055080 189 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.027
pituitary gland development GO:0021983 2 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.027
positive regulation of hormone biosynthetic process GO:0046886 4 0.027
Human
positive regulation of map kinase activity GO:0043406 80 0.027
positive regulation of stem cell differentiation GO:2000738 29 0.027
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
kidney epithelium development GO:0072073 25 0.027
hindlimb morphogenesis GO:0035137 2 0.027
skin development GO:0043588 76 0.027
covalent chromatin modification GO:0016569 254 0.027
metanephros development GO:0001656 16 0.027
positive regulation of cell motility GO:2000147 177 0.027
vesicle mediated transport GO:0016192 371 0.027
regulation of purine nucleotide catabolic process GO:0033121 205 0.027
anterior posterior axis specification embryo GO:0008595 2 0.026
mesonephros development GO:0001823 17 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
cytokine production GO:0001816 247 0.026
Human
regulation of nucleoside metabolic process GO:0009118 209 0.026
positive regulation of cellular component movement GO:0051272 181 0.026
regeneration GO:0031099 4 0.026
interspecies interaction between organisms GO:0044419 156 0.026
organonitrogen compound biosynthetic process GO:1901566 200 0.026
somitogenesis GO:0001756 2 0.026
activation of protein kinase activity GO:0032147 90 0.026
hard palate development GO:0060022 1 0.026
mitotic cell cycle process GO:1903047 286 0.026
protein ubiquitination GO:0016567 314 0.026
glycosyl compound catabolic process GO:1901658 413 0.026
branching involved in ureteric bud morphogenesis GO:0001658 9 0.026
regulation of nucleotide catabolic process GO:0030811 205 0.026
regulation of cell morphogenesis GO:0022604 153 0.026
sensory perception GO:0007600 103 0.025
pulmonary vein morphogenesis GO:0060577 1 0.025
response to growth factor GO:0070848 205 0.025
cellular response to lipid GO:0071396 127 0.025
regulation of canonical wnt signaling pathway GO:0060828 88 0.025
intracellular receptor signaling pathway GO:0030522 104 0.025
cellular cation homeostasis GO:0030003 163 0.025
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 1 0.025
peptidyl tyrosine phosphorylation GO:0018108 170 0.025
positive regulation of proteolysis GO:0045862 142 0.025
luteinizing hormone secretion GO:0032275 1 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
inorganic ion transmembrane transport GO:0098660 231 0.025
regulation of intracellular transport GO:0032386 195 0.024
cellular metal ion homeostasis GO:0006875 146 0.024
anion transport GO:0006820 161 0.024
digestive tract morphogenesis GO:0048546 56 0.024
regulation of cardioblast differentiation GO:0051890 4 0.024
reproductive system development GO:0061458 56 0.024
oocyte development GO:0048599 1 0.024
cell aggregation GO:0098743 1 0.024
gtp catabolic process GO:0006184 237 0.024
muscle system process GO:0003012 81 0.024
forebrain neuron differentiation GO:0021879 3 0.024
positive regulation of mesonephros development GO:0061213 2 0.024
neural tube patterning GO:0021532 2 0.024
hair follicle morphogenesis GO:0031069 2 0.024
tripartite regional subdivision GO:0007351 2 0.024
sensory perception of pain GO:0019233 4 0.024
nucleocytoplasmic transport GO:0006913 176 0.024
regulation of kidney size GO:0035564 2 0.024
motor neuron axon guidance GO:0008045 2 0.024
positive regulation of secretion by cell GO:1903532 108 0.024
multi organism cellular process GO:0044764 156 0.024
nephron epithelium development GO:0072009 23 0.024
negative regulation of protein modification process GO:0031400 200 0.023
protein oligomerization GO:0051259 173 0.023
outflow tract septum morphogenesis GO:0003148 4 0.023
developmental process involved in reproduction GO:0003006 66 0.023
mesonephric tubule development GO:0072164 14 0.023
regulation of body fluid levels GO:0050878 99 0.023
regulation of gtp catabolic process GO:0033124 180 0.023
positive regulation of neural precursor cell proliferation GO:2000179 2 0.023
embryonic eye morphogenesis GO:0048048 2 0.023
spemann organizer formation GO:0060061 1 0.023
branch elongation involved in ureteric bud branching GO:0060681 2 0.023
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
primary neural tube formation GO:0014020 3 0.023
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.023
endocrine pancreas development GO:0031018 11 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.023
cerebellum development GO:0021549 2 0.023
regulation of peptide transport GO:0090087 62 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.022
Human
positive regulation of organelle organization GO:0010638 195 0.022
leukocyte differentiation GO:0002521 98 0.022
blastocyst development GO:0001824 3 0.022
epithelial cell development GO:0002064 34 0.022
ureteric bud morphogenesis GO:0060675 10 0.022
single organism cell adhesion GO:0098602 179 0.022
salivary gland morphogenesis GO:0007435 4 0.022
regulation of peptide hormone secretion GO:0090276 41 0.022
epithelial to mesenchymal transition GO:0001837 48 0.022
cellular ion homeostasis GO:0006873 168 0.022
regulation of neurogenesis GO:0050767 82 0.022
dna repair GO:0006281 198 0.022
regulation of cardiac muscle cell proliferation GO:0060043 4 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
leukocyte migration GO:0050900 107 0.022
response to oxygen levels GO:0070482 100 0.022
Human
otic vesicle development GO:0071599 1 0.022
protein localization to nucleus GO:0034504 136 0.022
ventral spinal cord development GO:0021517 1 0.022

SIM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.046
Human
musculoskeletal system disease DOID:17 223 0.044
disease of cellular proliferation DOID:14566 174 0.033
cancer DOID:162 167 0.030
sensory system disease DOID:0050155 203 0.030
nervous system disease DOID:863 431 0.030
urinary system disease DOID:18 40 0.028
eye and adnexa disease DOID:1492 150 0.026
eye disease DOID:5614 149 0.025
organ system cancer DOID:0050686 164 0.024
bone disease DOID:0080001 88 0.023
connective tissue disease DOID:65 109 0.023
kidney disease DOID:557 36 0.022