Homo sapiens

73 known processes

E4F1

E4F transcription factor 1

(Aliases: E4F,MGC99614)

E4F1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 393 0.246
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.113
regulation of cellular ketone metabolic process GO:0010565 50 0.103
regulation of cellular amino acid metabolic process GO:0006521 6 0.089
cellular ketone metabolic process GO:0042180 80 0.080
post embryonic development GO:0009791 2 0.063
regulation of cellular amine metabolic process GO:0033238 11 0.057
cellular amino acid metabolic process GO:0006520 116 0.056
positive regulation of cell death GO:0010942 263 0.053
cellular macromolecular complex assembly GO:0034622 324 0.052
negative regulation of protein metabolic process GO:0051248 391 0.052
positive regulation of programmed cell death GO:0043068 249 0.049
positive regulation of apoptotic process GO:0043065 246 0.048
rna processing GO:0006396 255 0.046
amine metabolic process GO:0009308 44 0.044
cellular amine metabolic process GO:0044106 41 0.044
regulation of kinase activity GO:0043549 314 0.044
ras protein signal transduction GO:0007265 73 0.043
ribonucleoside triphosphate catabolic process GO:0009203 391 0.043
negative regulation of catalytic activity GO:0043086 335 0.042
regulation of cell differentiation GO:0045595 393 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.040
regulation of protein kinase activity GO:0045859 289 0.039
regulation of transferase activity GO:0051338 355 0.039
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
negative regulation of developmental process GO:0051093 247 0.035
protein ubiquitination GO:0016567 314 0.034
negative regulation of cell cycle GO:0045786 193 0.034
negative regulation of cellular amine metabolic process GO:0033239 3 0.033
apoptotic signaling pathway GO:0097190 268 0.033
cell fate determination GO:0001709 3 0.033
cellular component morphogenesis GO:0032989 314 0.032
positive regulation of phosphorylation GO:0042327 394 0.032
regulation of protein transport GO:0051223 213 0.032
protein localization to organelle GO:0033365 280 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.032
protein localization to membrane GO:0072657 160 0.031
intracellular protein transport GO:0006886 270 0.031
secretion by cell GO:0032940 226 0.030
protein modification by small protein conjugation GO:0032446 342 0.030
hematopoietic or lymphoid organ development GO:0048534 186 0.030
regulation of cytoskeleton organization GO:0051493 177 0.029
cellular macromolecule catabolic process GO:0044265 380 0.029
microtubule based process GO:0007017 210 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
positive regulation of cellular component organization GO:0051130 376 0.028
female gamete generation GO:0007292 2 0.028
protein maturation GO:0051604 233 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
meiosis i GO:0007127 4 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
membrane organization GO:0061024 292 0.027
spermatid development GO:0007286 4 0.027
regulation of gene expression epigenetic GO:0040029 73 0.027
chromatin modification GO:0016568 298 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.026
multicellular organismal aging GO:0010259 3 0.026
determination of adult lifespan GO:0008340 2 0.026
rna interference GO:0016246 4 0.025
positive regulation of cell differentiation GO:0045597 211 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
protein acetylation GO:0006473 116 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
locomotory behavior GO:0007626 1 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
regulation of proteolysis GO:0030162 293 0.024
negative regulation of cell death GO:0060548 345 0.024
response to abiotic stimulus GO:0009628 336 0.024
regulation of cell cycle process GO:0010564 266 0.024
organophosphate catabolic process GO:0046434 430 0.024
negative regulation of phosphorylation GO:0042326 174 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.023
cell morphogenesis GO:0000902 296 0.023
peptidyl tyrosine phosphorylation GO:0018108 170 0.023
atp metabolic process GO:0046034 176 0.023
vesicle mediated transport GO:0016192 371 0.023
ncrna processing GO:0034470 83 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
compound eye development GO:0048749 1 0.023
nervous system development GO:0007399 293 0.022
neuromuscular junction development GO:0007528 3 0.022
protein catabolic process GO:0030163 325 0.022
response to oxygen containing compound GO:1901700 369 0.022
regeneration GO:0031099 4 0.022
positive regulation of cell development GO:0010720 92 0.022
long term memory GO:0007616 2 0.022
cell projection organization GO:0030030 252 0.021
regulation of mitotic cell cycle GO:0007346 189 0.021
Mouse
single organism membrane organization GO:0044802 268 0.021
positive regulation of transport GO:0051050 336 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.020
oogenesis GO:0048477 2 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
regulation of protein localization GO:0032880 296 0.020
regulation of intracellular transport GO:0032386 195 0.020
spermatid differentiation GO:0048515 4 0.020
metencephalon development GO:0022037 2 0.020
positive regulation of developmental process GO:0051094 314 0.020
meiotic chromosome segregation GO:0045132 4 0.020
mitochondrion organization GO:0007005 156 0.019
protein processing GO:0016485 226 0.019
embryonic digestive tract morphogenesis GO:0048557 2 0.019
cell cell signaling GO:0007267 155 0.019
regulation of cell development GO:0060284 161 0.018
single organism cellular localization GO:1902580 332 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.017
purine containing compound catabolic process GO:0072523 411 0.017
system process GO:0003008 349 0.017
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
positive regulation of protein transport GO:0051222 135 0.017
histone modification GO:0016570 251 0.017
growth GO:0040007 202 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
cytoplasmic transport GO:0016482 379 0.017
organelle fission GO:0048285 149 0.017
cell growth GO:0016049 160 0.017
hindbrain development GO:0030902 3 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
positive regulation of nervous system development GO:0051962 54 0.017
photoreceptor cell differentiation GO:0046530 2 0.017
cell development GO:0048468 328 0.016
segmentation GO:0035282 4 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
response to lipid GO:0033993 206 0.016
synaptic transmission GO:0007268 61 0.016
cellular protein catabolic process GO:0044257 261 0.016
regulation of secretion GO:0051046 194 0.016
collateral sprouting GO:0048668 2 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
response to external biotic stimulus GO:0043207 261 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
neural tube formation GO:0001841 3 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
chromatin organization GO:0006325 351 0.016
glycoprotein metabolic process GO:0009100 110 0.016
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
cell cycle checkpoint GO:0000075 117 0.015
neurogenesis GO:0022008 169 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
protein oligomerization GO:0051259 173 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
cell projection morphogenesis GO:0048858 129 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
methylation dependent chromatin silencing GO:0006346 3 0.015
gtp metabolic process GO:0046039 239 0.015
mrna metabolic process GO:0016071 175 0.015
innate immune response GO:0045087 178 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
positive regulation of apoptotic signaling pathway GO:2001235 70 0.015
generation of neurons GO:0048699 152 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
regulation of secretion by cell GO:1903530 177 0.015
protein acylation GO:0043543 138 0.015
cell part morphogenesis GO:0032990 137 0.014
positive regulation of catabolic process GO:0009896 310 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
ribonucleoprotein complex biogenesis GO:0022613 116 0.014
organic acid biosynthetic process GO:0016053 97 0.014
regulation of cell division GO:0051302 116 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.014
tissue regeneration GO:0042246 3 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.014
defense response GO:0006952 315 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
neurotransmitter secretion GO:0007269 4 0.014
hemopoiesis GO:0030097 180 0.014
negative regulation of growth GO:0045926 97 0.014
nucleotide catabolic process GO:0009166 408 0.014
reproductive process GO:0022414 106 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.013
response to fungus GO:0009620 4 0.013
positive regulation of cell projection organization GO:0031346 64 0.013
endomembrane system organization GO:0010256 196 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
peptidyl lysine modification GO:0018205 144 0.013
covalent chromatin modification GO:0016569 254 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
mitotic cell cycle process GO:1903047 286 0.013
cell division GO:0051301 168 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
protein polyubiquitination GO:0000209 110 0.013
negative regulation of kinase activity GO:0033673 106 0.013
negative regulation of transferase activity GO:0051348 124 0.013
positive regulation of proteolysis GO:0045862 142 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
cellular homeostasis GO:0019725 196 0.013
mitochondrial membrane organization GO:0007006 40 0.013
small molecule biosynthetic process GO:0044283 157 0.013
secretion GO:0046903 254 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
regulation of response to external stimulus GO:0032101 222 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
negative regulation of protein modification process GO:0031400 200 0.013
actin filament based process GO:0030029 224 0.012
nucleosome organization GO:0034728 66 0.012
epidermis morphogenesis GO:0048730 3 0.012
lipid metabolic process GO:0006629 381 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
salivary gland morphogenesis GO:0007435 4 0.012
response to other organism GO:0051707 261 0.012
cell cycle phase transition GO:0044770 173 0.012
histone methylation GO:0016571 60 0.012
memory GO:0007613 3 0.012
convergent extension GO:0060026 1 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
negative regulation of protein deubiquitination GO:0090086 3 0.012
circadian behavior GO:0048512 2 0.012
regulation of mitochondrial membrane permeability GO:0046902 25 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
positive regulation of neural precursor cell proliferation GO:2000179 2 0.012
nucleoside catabolic process GO:0009164 408 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
regulation of protein catabolic process GO:0042176 155 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
dna packaging GO:0006323 77 0.012
oocyte development GO:0048599 1 0.012
mitotic cell cycle GO:0000278 326 0.012
Mouse
oocyte differentiation GO:0009994 2 0.012
regulation of growth GO:0040008 165 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
peptidyl tyrosine modification GO:0018212 170 0.011
lens development in camera type eye GO:0002088 2 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
neuron differentiation GO:0030182 138 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.011
inner ear morphogenesis GO:0042472 4 0.011
regulation of peptidase activity GO:0052547 180 0.011
carbohydrate metabolic process GO:0005975 207 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
chromatin remodeling GO:0006338 55 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
neurological system process GO:0050877 163 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
forebrain neuron differentiation GO:0021879 3 0.011
forebrain generation of neurons GO:0021872 3 0.011
response to ionizing radiation GO:0010212 65 0.011
biological adhesion GO:0022610 331 0.011
establishment of tissue polarity GO:0007164 3 0.011
ameboidal type cell migration GO:0001667 135 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
thymus development GO:0048538 3 0.011
positive regulation of organelle organization GO:0010638 195 0.011
regulation of protein deubiquitination GO:0090085 4 0.011
cellular lipid metabolic process GO:0044255 303 0.011
rna splicing GO:0008380 131 0.011
positive regulation of neuron differentiation GO:0045666 40 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
negative regulation of catabolic process GO:0009895 104 0.011
regulation of nervous system development GO:0051960 88 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
response to nutrient levels GO:0031667 81 0.011
regulation of mapk cascade GO:0043408 262 0.011
regulation of cell growth GO:0001558 135 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
positive regulation of transferase activity GO:0051347 227 0.010
defense response to fungus GO:0050832 4 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010
nuclear division GO:0000280 128 0.010
positive regulation of neurogenesis GO:0050769 49 0.010
mrna processing GO:0006397 133 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
neuron fate commitment GO:0048663 2 0.010
chemical homeostasis GO:0048878 306 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
protein dna complex subunit organization GO:0071824 80 0.010
dna conformation change GO:0071103 113 0.010
internal peptidyl lysine acetylation GO:0018393 97 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
regulation of cell projection organization GO:0031344 107 0.010
regulation of anatomical structure size GO:0090066 101 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010
rostrocaudal neural tube patterning GO:0021903 1 0.010
gonad development GO:0008406 34 0.010
regulation of neurogenesis GO:0050767 82 0.010
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 16 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
neuron death GO:0070997 65 0.010
regulation of receptor activity GO:0010469 47 0.010
cellular protein complex assembly GO:0043623 188 0.010
positive regulation of cytoskeleton organization GO:0051495 83 0.010
fatty acid metabolic process GO:0006631 115 0.010

E4F1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.043
cancer DOID:162 167 0.042
organ system cancer DOID:0050686 164 0.042
musculoskeletal system disease DOID:17 223 0.018
connective tissue disease DOID:65 109 0.015
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
nervous system disease DOID:863 431 0.014
eye disease DOID:5614 149 0.014
disease of metabolism DOID:0014667 295 0.014
gastrointestinal system cancer DOID:3119 52 0.011